Annales De Dermatologie Et De Venereologie最新文献

{"title":"Eruptive pyogenic granulomas of the proximal nail folds as a complication of cast immobilization","authors":"M. Aboudourib, O. Khadiri, M. Abid, O. Hocar, S. Amal","doi":"10.1016/j.annder.2025.103384","DOIUrl":"10.1016/j.annder.2025.103384","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 3","pages":"Article 103384"},"PeriodicalIF":3.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144124731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of eosinophilic dermatosis of hematologic malignancy with omalizumab","authors":"E. Hassan, B. Papouin, K. Belhadj, S. Ingen-Housz-Oro","doi":"10.1016/j.annder.2025.103383","DOIUrl":"10.1016/j.annder.2025.103383","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 3","pages":"Article 103383"},"PeriodicalIF":3.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144125283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"French national protocol for diagnosis and management of drug reaction with eosinophilia and systemic symptoms (DRESS) in adults and children","authors":"S. Ingen-Housz-Oro , C. Bernier , H. Assier , F. Tétart , F. Dezoteux , A. Gaillet , B. Bensaid , A. Welfringer-Morin , N. de Prost , D. Staumont-Sallé , M. Tauber , K. Bel Hareth , P. Sanchez , S. Guendouz , C. Hua , S. Fourati , F. Schlemmer , G. Gourier , L. Nakad , C. Hoffmann , V. Descamps","doi":"10.1016/j.annder.2025.103381","DOIUrl":"10.1016/j.annder.2025.103381","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 3","pages":"Article 103381"},"PeriodicalIF":3.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144106353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of intramatricial triamcinolone acetonide injections in nail lichen planus: A retrospective data analysis","authors":"C. Grover,&nbsp;B. Aggawal","doi":"10.1016/j.annder.2025.103382","DOIUrl":"10.1016/j.annder.2025.103382","url":null,"abstract":"<div><h3>Background</h3><div>Nail lichen planus (NLP) impacts 10–15% of patients with lichen planus and is characterized by discomfort and the potential for permanent damage. Intralesional triamcinolone acetonide (TA) is a first-line treatment; however, comprehensive efficacy data is lacking.</div></div><div><h3>Objective</h3><div>To evaluate and compare changes in nail lichen planus severity using the Nail Lichen Planus Severity Index (NALSI) in affected fingernails and toenails treated with intramatricial TA (5 mg/ml) injections at 4-weekly and 8-weekly intervals, respectively.</div></div><div><h3>Methods</h3><div>A retrospective analysis was done for 17 NLP patients treated over 11 years with intramatricial TA (5 mg/ml). Photographic records from each visit were analysed to score disease severity using NALSI. Comparison was made of the percentage of fingernails versus toenails achieving NALSI-50 (50% reduction in NALSI over baseline) at the 3rd and 6th injections.</div></div><div><h3>Results</h3><div>These 17 patients had 232 nails (68.2%) affected by lichen planus, of which 130 (56%) were fingernails and 102 (44%) were toenails. The mean baseline NALSI of 7.4 ± 2.7 for fingernails, decreased to 6.6 ± 2.7 at the 3rd session, and 4.2 ± 3.2 at 6th session, while for toenails it dropped from 7.02 ± 2.6 to 6.6 ± 2.5 and 5.9 ± 3.0, respectively. By the treatment endpoint (4/8 weeks after fifth injection, respectively, for fingernails and toenails), NALSI-50 reduction was achieved in 40.7% fingernails and 10.8% toenails; while NALSI-75 reduction was achieved in 21.5% fingernails and 4.9% toenails, respectively. Throughout the course of the therapeutic intervention, the proportion of fingernails exhibiting irreversible alterations remained stable at 11.5%. However, a notable increase was observed for toenails, rising from 11.7% at baseline to 13.7% by the conclusion of the study. The adverse effects included pain (23.5% of patients), proximal nail-fold hyperpigmentation and atrophy (23.5%), and subungual hematoma (17.6%).</div></div><div><h3>Conclusion</h3><div>Intramatricial TA (5 mg/ml) injections are safe and effective in the treatment of NLP, with greater efficacy being noted in fingernails.</div></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 3","pages":"Article 103382"},"PeriodicalIF":3.1,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143937487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immune checkpoint inhibitors induced subcutaneous panniculitis-like T-cell lymphoma","authors":"S. Idoudi,&nbsp;A. De Masson,&nbsp;C. Gandon,&nbsp;M. Battistella,&nbsp;S. Caillat-Zucman,&nbsp;S. Pinel,&nbsp;L. Vercellino,&nbsp;F. Jouenne,&nbsp;S. Mourah,&nbsp;B. Baroudjian,&nbsp;C. Lebbe","doi":"10.1016/j.annder.2025.103366","DOIUrl":"10.1016/j.annder.2025.103366","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 3","pages":"Article 103366"},"PeriodicalIF":3.1,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143905842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apremilast: Real-life efficacy and safety in psoriasis limited to the nails","authors":"M. Iorizzo ,&nbsp;G. Damiani ,&nbsp;S.R. Lipner ,&nbsp;A. Pacifico ,&nbsp;D. Rigopoulos ,&nbsp;A. Sechi ,&nbsp;A. Villani ,&nbsp;I. Zaraa ,&nbsp;B. Richert","doi":"10.1016/j.annder.2025.103377","DOIUrl":"10.1016/j.annder.2025.103377","url":null,"abstract":"<div><h3>Background</h3><div>Apremilast, an oral phosphodiesterase inhibitor, offers advantages in psoriasis patients in whom biologics are not approved or accepted and where topical treatments have failed. Psoriasis involving the nails, scalp, and genitals is difficult to treat and is associated with a significant decrease in quality of life, requiring an effective treatment.</div></div><div><h3>Objectives</h3><div>This study aimed to retrospectively assess the efficacy and safety of apremilast 30 mg twice daily in treating psoriasis limited to the nails.</div></div><div><h3>Methods</h3><div>The charts of 55 adult patients with nail psoriasis treated with apremilast were retrospectively evaluated. Baseline characteristics, including the nail psoriasis severity index (NAPSI) and dermatology life quality index (DLQI), were recorded.</div></div><div><h3>Results</h3><div>At 6 months of treatment, a statistically significant decrease in both the NAPSI score (44.7 ± 26.9 vs. 19.03 ± 14.2) and the DLQI score (14.5 ± 5 vs. 7.2 ± 4.1) was observed (<em>p</em> &lt; 0.01). None of the patients discontinued the treatment due to side effects.</div></div><div><h3>Conclusions</h3><div>This study shows improvements in nail psoriasis severity and quality of life with apremilast treatment. Despite potential confounders like psoriatic arthritis, smoking, and manual work, consistent improvements were observed. Apremilast appears to be a valuable treatment option for nail psoriasis. However, further prospective studies are necessary to address the limitations of this retrospective analysis and explore additional endpoints.</div></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103377"},"PeriodicalIF":3.1,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143898928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the French version of the hidradenitis suppurativa quality of life (HiSQOL) questionnaire","authors":"S. Berros ,&nbsp;A.-S. Ficheux ,&nbsp;L. Misery ,&nbsp;N. Jouan ,&nbsp;E. Brenaut","doi":"10.1016/j.annder.2025.103379","DOIUrl":"10.1016/j.annder.2025.103379","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103379"},"PeriodicalIF":3.1,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143898994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse molluscum contagiosum associated with GATA2 deficiency","authors":"C. Bourseau-Quetier,&nbsp;M.-S. Doutre","doi":"10.1016/j.annder.2025.103378","DOIUrl":"10.1016/j.annder.2025.103378","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103378"},"PeriodicalIF":3.1,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of excess weight on clinical features of psoriasis and efficacy of biologic therapies in children with severe psoriasis: Analysis of data from the BiPe cohorts","authors":"E. Mahé ,&nbsp;V. di Lernia ,&nbsp;A.-C. Bursztejn ,&nbsp;S. Hadj-Rabia ,&nbsp;N. Quiles-Tsimaratos ,&nbsp;A. Belloni Fortina ,&nbsp;I. Neri ,&nbsp;A. Lasek ,&nbsp;A. Maruani ,&nbsp;G. Chaby ,&nbsp;J. Gottlieb ,&nbsp;S. Barbarot ,&nbsp;H. Aubert ,&nbsp;C. Droitcourt ,&nbsp;S. Mallet ,&nbsp;A. Phan ,&nbsp;M. Severino-Freire ,&nbsp;F. Boralévi ,&nbsp;H. Barthélémy ,&nbsp;C. Girard ,&nbsp;A. Beauchet","doi":"10.1016/j.annder.2025.103376","DOIUrl":"10.1016/j.annder.2025.103376","url":null,"abstract":"<div><h3>Background</h3><div>Being overweight or obese is associated with both the occurrence of childhood psoriasis and increased severity thereof. We evaluated the impact of being overweight or obese on the clinical features of severe psoriasis in children treated with etanercept, adalimumab, or ustekinumab, and on the therapeutic effectiveness of these treatments using data from the BiPe cohorts.</div></div><div><h3>Patients and methods</h3><div>Children from the BiPe cohorts with available baseline body mass index data were included. Data from two groups, “normal weight” and “overweight-to-obese” (OTO), and from two OTO subgroups, overweight and obese, were analyzed.</div></div><div><h3>Results</h3><div>Of the 134 children included, 98 (73.1%) were of normal weight, and 36 (26.9%) were OTO, including 21 (15.7%) overweight and 15 (11.2%) obese children. There were no between-group differences in age at psoriasis onset, family history, clinical features, or severity. Compared to the normal weight group, psoriatic arthritis was more frequent in the OTO group (5.1% versus 16.7% respectively; <em>P</em> = 0.03) and in the overweight and obese subgroups (5.1% versus 14.3% and 20.0%, respectively; <em>P</em> = 0.08). Analysis of PASI scores after 3 months of treatment suggested that biologic therapy efficacy was higher for the OTO group than the normal weight group. Drug continuation rates tended to be lower for the OTO group, particularly for adalimumab (<em>P</em> = 0.0002).</div></div><div><h3>Discussion</h3><div>OTO status was associated with a higher frequency of psoriatic arthritis in children with psoriasis. Except for lower rates of adalimumab continuation, overall biologic therapy efficacy was similar in the normal and OTO groups. Studies involving larger cohorts are needed to confirm these findings.</div></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103376"},"PeriodicalIF":3.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bullous pemphigoid following radiotherapy combined with ipilimumab-nivolumab therapy","authors":"A. Pankakoski,&nbsp;J. Panelius,&nbsp;N. Kluger","doi":"10.1016/j.annder.2025.103367","DOIUrl":"10.1016/j.annder.2025.103367","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103367"},"PeriodicalIF":3.1,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}