Annales De Dermatologie Et De Venereologie最新文献

{"title":"Hobnail hemangioma","authors":"A. Cuypers , S. Blaise","doi":"10.1016/j.annder.2025.103343","DOIUrl":"10.1016/j.annder.2025.103343","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103343"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A giant patch of dermatoporosis secondary to inappropriate topical corticosteroid use","authors":"N. Kluger","doi":"10.1016/j.annder.2025.103348","DOIUrl":"10.1016/j.annder.2025.103348","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103348"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lacosamide-induced nodulocystic acne with keloid scarring","authors":"G. Gasparini, C. Cabona, B. Piazza, I. Pappalardo, F. Villani, E. Cozzani","doi":"10.1016/j.annder.2025.103361","DOIUrl":"10.1016/j.annder.2025.103361","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103361"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of the time-of-day in the administration of immunotherapy and its efficacy in patients with advanced melanoma: A retrospective observational study","authors":"M. Amici ,&nbsp;E. Neveu ,&nbsp;F. Poizeau ,&nbsp;J. Edeline ,&nbsp;T. Lesimple ,&nbsp;E. Oger ,&nbsp;G. Danton ,&nbsp;A. Dupuy ,&nbsp;M. Fouchard","doi":"10.1016/j.annder.2025.103371","DOIUrl":"10.1016/j.annder.2025.103371","url":null,"abstract":"<div><h3>Background</h3><div>Certain publications suggest that immunotherapy would be more effective if it were synchronised with the circadian oscillations of the immune system. We hypothesised that late treatment delivery in melanoma patients would correlate with worse survival outcomes.</div></div><div><h3>Patients and methods</h3><div>We conducted a monocentric retrospective study in patients with advanced cutaneous melanoma receiving immune checkpoint inhibitors as first-line therapy. We used the median clock time of all infusions (11:00) as the cut-off point to differentiate morning from afternoon. Patients were allocated to the morning or afternoon group depending on whether they had received &gt;50% of their infusions before or after 11:00. A propensity score was calculated. Timing groups were assessed for association with overall and progression-free survival using a Cox proportional hazards model, survival curves were compared, and treatment-related adverse events (AEs) were analysed.</div></div><div><h3>Results</h3><div>We included 154 patients treated with frontline immunotherapy in a metastatic setting from 1 January 2013 to 1 January 2022, with a median age of 67 years (interquartile range: 56–75). Late treatment delivery was associated neither with worse overall survival (median not reached [34.9-not estimable] vs. 70.8 months; hazard ratio (HR) = 0.94 [0.63–1.39]) nor worse progression-free survival (22.3 vs. 26.5; HR = 0.99 [0.71–1.38]), and there were no differences in survival outcomes between the groups. Severe treatment-related AEs were significantly more frequent in the afternoon group than in the morning group (33 [34%] vs. 6 [11%] respectively, weighted <em>p</em>-value = 0.004).</div></div><div><h3>Conclusion</h3><div>Timing was not associated with worse efficacy outcomes, but morning administration appears to improve safety.</div></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103371"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leser-Trélat sign on BRAF inhibitors","authors":"C. Decaestecker ,&nbsp;R. Levard ,&nbsp;J.-M. L’Orphelin","doi":"10.1016/j.annder.2025.103368","DOIUrl":"10.1016/j.annder.2025.103368","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103368"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paradoxical erosive oral lichen planus possibly induced by abatacept","authors":"J. Boo,&nbsp;B. Mille,&nbsp;M. Boileau,&nbsp;E. Ledoult,&nbsp;M. Aho-Stichelbout,&nbsp;F. Dezoteux,&nbsp;D. Staumont-Salle","doi":"10.1016/j.annder.2025.103346","DOIUrl":"10.1016/j.annder.2025.103346","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103346"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143562085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acrodermatitis continua of Hallopeau successfully treated with spesolimab","authors":"M. Descos,&nbsp;C. Girard,&nbsp;M. Girod,&nbsp;G. Boursier,&nbsp;D. Bessis","doi":"10.1016/j.annder.2025.103347","DOIUrl":"10.1016/j.annder.2025.103347","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103347"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of spesolimab in the treatment of generalized pustular psoriasis in elderly patients","authors":"G. Russo ,&nbsp;S. Dumont ,&nbsp;S. Menzinger,&nbsp;L. Rocher,&nbsp;E. Laffitte","doi":"10.1016/j.annder.2025.103363","DOIUrl":"10.1016/j.annder.2025.103363","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103363"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic screening for skin cancers: Is it a good idea?","authors":"X. Humbert,&nbsp;J. Dupouy,&nbsp;V. Renard,&nbsp;D. Pouchain,&nbsp;B. Tudrej,&nbsp;H. Partouche,&nbsp;N. Rousselot,&nbsp;Y.-M. Vincent,&nbsp;G. Ibanez,&nbsp;A. Malmartel,&nbsp;M. Jego,&nbsp;S. Gilberg,&nbsp;M. Francois,&nbsp;E. Ferrat,&nbsp;O. Saint-Lary,&nbsp;R. Boussageon,&nbsp;Scientific Council of the French College of Academic General Practitioners (Collège national des généralistes enseignants, Conseil scientifique)","doi":"10.1016/j.annder.2025.103350","DOIUrl":"10.1016/j.annder.2025.103350","url":null,"abstract":"","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103350"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of the proportion of skin cancers attributable to occupational sun exposure in Reunion Island","authors":"C. Fera ,&nbsp;A. Pausé ,&nbsp;C. Louacheni ,&nbsp;C. Kwan ,&nbsp;C. Scalbert ,&nbsp;E. Chirpaz ,&nbsp;A. Bertolotti","doi":"10.1016/j.annder.2025.103351","DOIUrl":"10.1016/j.annder.2025.103351","url":null,"abstract":"<div><h3>Background</h3><div>The increasing prevalence of cutaneous malignancies has led to their categorization as a public health concern. The main risk factor is ultraviolet (UV) radiation, which can be particularly high in certain overseas territories. As a result, outdoor workers constitute a high-risk population.</div></div><div><h3>Objectives</h3><div>The aim of this study was to determine the proportion of skin cancers potentially attributable to occupational sun exposure in Reunion Island.</div><div>The increasing prevalence of skin cancer in recent years has led to its recognition as a significant public health concern. The primary risk factor is ultraviolet (UV) radiation, which has been observed to reach elevated levels in certain overseas territories. Consequently, individuals engaged in outdoor work are considered a high-risk population. The objectives of this study were to determine the proportion of skin cancers potentially attributable to occupational sun exposure in Reunion Island and to identify factors associated with such exposure.</div></div><div><h3>Methods</h3><div>This study covers all melanomas, cutaneous squamous cell carcinomas and a representative sample of basal cell carcinomas, diagnosed over one year in subjects who had worked for at least 3 years on the island. Telephone interviews were conducted with each subject to gather data on their exposure to sunlight during childhood, leisure activities and work. Cancers were classified as potentially attributable to work if the time spent in the sun at work was greater than the time spent in the sun during leisure time, taking into account sun protection data and the site of the skin cancer (areas exposed during work).</div></div><div><h3>Results</h3><div>Of the 329 people included, 37.7% had skin cancer(s) attributable to occupational UV exposure. Several high-risk professions were identified, including farmers. Among people surveyed, 93% reported that their employers had taken any steps to prevent sun exposure and 73% had never used sunscreen at work.</div></div><div><h3>Conclusion</h3><div>The percentage of people with skin cancer potentially attributable to occupational sun exposure in Reunion Island is considerable. Prevention and education on photoprotection in the workplace are essential. Recognition of skin cancer in exposed workers as an occupational disease should be considered in Reunion Island.</div></div>","PeriodicalId":7900,"journal":{"name":"Annales De Dermatologie Et De Venereologie","volume":"152 2","pages":"Article 103351"},"PeriodicalIF":3.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}