{"title":"Combothérapie par rituximab et anakinra dans le traitement d'une péricardite chronique compliquant une polyarthrite rhumatoïde","authors":"Nabil Belfeki , Nouha Ghriss , Houssem Hamrouni , Sonia Kammoun , Mazen Alloujami , Cyrus Moini","doi":"10.1016/j.ancard.2025.101865","DOIUrl":"10.1016/j.ancard.2025.101865","url":null,"abstract":"<div><div>Pericarditis is often an asymptomatic complication of rheumatoid arthritis. It rarely progresses towards tamponade or chronicity. There is little data on the therapeutic management of this serious complication. Recently, some rare data evaluating the place of biotherapy in rheumatoid pericarditis have been published. We report the observation of a patient with immunopositive rheumatoid arthritis escaping several lines of treatment who developed tamponade which recurred after surgical drainage. Only combotherapy with rituximab and anakinra allowed the induction of rheumatological remission and the disappearance of pericarditis<strong>.</strong></div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 2","pages":"Article 101865"},"PeriodicalIF":0.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Ait Mokhtar , A. Azaza , A. Azzouz , M. Kara , M. Salem , M. Saidane , A. Sik , S. Benkhedda
{"title":"Caractéristiques et mortalité intrahospitalières des patients âgés, admis pour syndrome coronaire aigu avec sus décalage du segment ST et traités par angioplastie primaire dans un centre tertiaire en Algerie","authors":"O. Ait Mokhtar , A. Azaza , A. Azzouz , M. Kara , M. Salem , M. Saidane , A. Sik , S. Benkhedda","doi":"10.1016/j.ancard.2024.101857","DOIUrl":"10.1016/j.ancard.2024.101857","url":null,"abstract":"<div><div>Actually, elderly patients are always admitted to the hospital for acute coronary syndrome with ST-segment elevation myocardial infarction (STEMI), and primary percutaneous coronary intervention (PPCI) is done in this setting. No specific recommendations were available for this population of octogenarians and nonagenarians because they were excluded from randomized trials. For these reasons, it is important to assess their clinical and prognostic characteristics. Our registry includes 1057 STEMI patients treated by PPCI, we analyzed data from 884 patients and divided them into 2 groups, the first one, aged more than 80 years (G1), and the second one below 80 years old(G2). We find more comorbidities and lower mal sex predominance in G1. Typical angina chest pain was the most common presentation symptom in both groups; however, atypical presentation was significantly more frequent in the elderly. Interestingly patients in G1 have lower ST regression than G2, despite this; intra-hospital mortality remains acceptable.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 2","pages":"Article 101857"},"PeriodicalIF":0.3,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thibaut Renotte , Théophile Tamakloe , Jean-Louis Mariage , Xavier Michel , Baudry Gubin , Philippe Oriot , Emmanuelle Paternotte
{"title":"Approche diagnostique et prise en charge d'un thrombus intraventriculaire gauche compliqué par une embolie inattendue : un cas clinique","authors":"Thibaut Renotte , Théophile Tamakloe , Jean-Louis Mariage , Xavier Michel , Baudry Gubin , Philippe Oriot , Emmanuelle Paternotte","doi":"10.1016/j.ancard.2025.101863","DOIUrl":"10.1016/j.ancard.2025.101863","url":null,"abstract":"<div><div>Left ventricular thrombus (LVT) is a serious complication of both ischemic and non-ischemic cardiomyopathies, with a high risk of morbidity and mortality due to systemic embolism. We present the case of a 73-year-old man with a history of myocardial infarction who subsequently developed an apical thrombus. Seven years after the initial event, this thrombus caused a splenic infarction complicated by an abscessed hematoma. This case underlines the critical role of advanced medical imaging in the diagnosis of LVT and highlights the emerging therapeutic potential of direct oral anticoagulants. It also highlights the challenges of diagnosing and managing LVT and the importance of reviewing the latest evidence to refine and optimize therapeutic strategies.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 2","pages":"Article 101863"},"PeriodicalIF":0.3,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Les faux anévrismes carotidiens au cours de la maladie de Behçet : nouveau cas inaugural de la maladie","authors":"Y. Lyazidi","doi":"10.1016/j.ancard.2025.101864","DOIUrl":"10.1016/j.ancard.2025.101864","url":null,"abstract":"<div><div>Arterial affection in Behçet's disease is serious and can be aneurysmal or thrombotic.</div><div>The literature on the characteristics of arterial aneurysms in Behçet's disease remains scarce.</div><div>This is a case report of a 19-year-old young male who was operated on for a false aneurysm of the left carotid bulb Aneurysm whose etiological investigation revealed Behçet's disease immediately complicated by the arterial localization.</div><div>The false aneurysm was excised and the carotid bulb was repaired with polytetrafluoroethylene prosthesis</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 2","pages":"Article 101864"},"PeriodicalIF":0.3,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hennebicq Sophie , Joly Emmanuel , Haberman David , Unger Philippe , De Cannière Didier , Leone Attilio
{"title":"Pseudo-anévrisme du trigone mitro-aortique : cas clinique et revue de littérature","authors":"Hennebicq Sophie , Joly Emmanuel , Haberman David , Unger Philippe , De Cannière Didier , Leone Attilio","doi":"10.1016/j.ancard.2024.101853","DOIUrl":"10.1016/j.ancard.2024.101853","url":null,"abstract":"<div><h3>Case Report</h3><div>We report the case of a 63-year-old patient who underwent aortic valve replacement with a biological valve for a bicuspid aortic stenosis, and LIMA-IVA single-bypass surgery. Two weeks later, he presented with <em>Enterococcus faecillis bacteremia</em>, attributed to left pyelonephritis and successfully treated with Amoxicillin. Two months after his surgery, he had a new bacteremia due to <em>Enterococcus faecalis</em> and we discovered a pseudo-aneurysm of the mitro-aortic trigone. Our patient is treated medically at first, before benefiting from the \"Hemi-Commando\" procedure.</div></div><div><h3>Discussion</h3><div>The mitro-aortic trigone is a fibrous area, located between the left half of the noncoronary cusp and the left coronary cusp of the aortic valve and the anterior leaflet of the mitral valve [<span><span>1</span></span>]. This area, important in the maintenance of mitral and aortic functions, [ii] is poorly vascularized and therefore very susceptible to infections and trauma [<span><span>2</span></span>]. Erosion of the aortic ring leads to the formation of a subvalvular abcess, secondarily detergated en then leads to the destruction of the trigone.</div></div><div><h3>Conclusions</h3><div>Pseudoaneurysm is a rare complication of aortic valve surgery and endocarditis. Given the risk of rupture, early surgery is recommended.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"Article 101853"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Origanum vulgare et risque hémorragique, à propos d'un cas","authors":"Imene Beghriche , Abdelaali Belhachem , Imene Hamidene , Allaoua Hicham Fendri","doi":"10.1016/j.ancard.2024.101856","DOIUrl":"10.1016/j.ancard.2024.101856","url":null,"abstract":"<div><h3>Introduction</h3><div>The use of medicinal plants in Algeria is an ancestral practice that remains relevant today. The population relies on plants to treat various diseases and everyday ailments, which can be dangerous, especially when taking medication [<span><span>1</span></span>,<span><span>2</span></span>]. The interaction between plants and medication can lead to a modification of the plasma concentrations of the latter, which can impact its therapeutic effectiveness and be responsible for toxicity or therapeutic failure [<span><span>1</span></span>,<span><span>2</span></span>]. The interaction can also be pharmacodynamic, resulting in the potentiation of the effect or its antagonism. The risk is even higher when the medication has a narrow therapeutic range or presents high inter- or intra-individual variability, such as with vitamin K antagonist anticoagulants.</div></div><div><h3>Clinical Case</h3><div>We report the case of patient B.Z., aged 77, who is suffering from complete atrial fibrillation (ACFA). The patient has been under antivitamin K (AVK) treatment with acenocoumarol for 8 years and has been followed at the central laboratory of Didouche Mourad Hospital since August 2019.</div><div>The patient has been stable with an INR within the therapeutic target range of <strong>2-3</strong> for 4 years. She is compliant and adheres to the dietary regimen. The dosage of acenocoumarol is alternated between <strong>1/2 tablet</strong> and <strong>1/4 tablet</strong>. On September 6, 2023, during a routine check-up, the patient's INR was <strong>6.42</strong>, and the PT was <strong>17.9%</strong>. The recommendation was to stop AVK and perform a control the following day. The interview revealed that the patient had started taking an infusion of oregano (<em>Origanum vulgare</em>), and occasionally verbena, at a rate of one <strong>200 ml cup</strong> per day for a week. On September 7, 2023, the INR decreased to <strong>3.80</strong> and the PT to <strong>26.9%</strong>, so the recommendation was to resume AVK at a dosage of <strong>1/4 tablet</strong> to <strong>1/2 tablet</strong>, with discontinuation of the herbal tea intake and an INR check after 72 hours. On the fourth day after resuming the anticoagulant, the INR was <strong>2.5</strong>. Despite being informed of the risk of interaction, the patient resumed taking the freshly picked oregano herbal tea from her garden. Given the patient's determination to continue her infusion, the recommendation was made to limit her intake, to prepare much more diluted infusions, and to reduce the dose of acenocoumarol to <strong>1/4 tablet</strong>; this allowed the stabilization of the patient's INR. The last check-up was performed on April 7, 2024, with an INR value of <strong>2.3</strong>.</div></div><div><h3>Results</h3><div>Oregano, a plant from the <em>Lamiaceae</em> family, is used in herbal tea to treat a wide range of diseases, including joint pain, respiratory conditions, and di","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"Article 101856"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimisation du traitement de l'insuffisance cardiaque à l'institut de cardiologie d'Abidjan","authors":"Marie Nina Koffi , Anicet Kassi Adoubi , Fatouma Sall , Loa Ambroise Gnaba , Florent Diby , Serge Armel Dakoi , Esaïe Soya","doi":"10.1016/j.ancard.2024.101854","DOIUrl":"10.1016/j.ancard.2024.101854","url":null,"abstract":"<div><h3>Introduction</h3><div>The aim of the study was to assess the level of treatment optimization after follow-up at discharge.</div></div><div><h3>Methods</h3><div>We conducted a retrospective study carried out from January 1st, 2016 to December 31st, 2018 in Abidjan Heart Institute with patients hospitalized for heart failure and reviewed in consultation.</div></div><div><h3>Results</h3><div>The study involved 350 patients with an average age of 53.53 ± 16.38 years (54% were males). The prescription of diuretics (92%) after optimization was at the mean and with maximum doses of 29.1% and 7.7%. ACEIs/ARBs (77.1%) had optimal and mean doses for ACEIs of 14.3% and 29.7%. With beta-blockers (72.6%) there was an improvement in doses at 35.4% for the average doses and 3.1%. for the maximum dose. Spironolactone (44.3%) kept the same average dose at 5.7% The median time of optimization was 287.05 days with a median of 140 days. Only 13.4% of patients were receiving optimal treatment at optimal doses. By logistic regression, the presence of LVEF ≤ 0,40 or LVEF= 0.41–0.49 or global heart failure (<em>P</em> < 0.001) favored drug optimization (OR = 24.68[7.15–82.22], <em>P</em> < 0.001); (OR = 11.39[3.25–39.86], <em>P</em> < 0.001) on the other hand, a high serum creatinine level was an obstacle for treatment optimization (OR = 0.92[0.88–0.96], <em>P</em> < 0.001).</div></div><div><h3>Conclusion</h3><div>The optimization of the treatment of heart failure is insufficient with too long delays in our context. The optimization time was so long. It could be improved by setting up a clinic to optimize the treatment of heart failure.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"Article 101854"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Soufiani , Z. Agoumy , M. Tribak , S. El Mhadi , Z. Fassi Fehri , H. Chraibi , L. Bakamel , O. Soussi , H. El Assili , K. Berrag , J. Raoui , FZ Hattab , Z. Idrissi , S. Essebany , H. Leghlimi , F. Lachhab , N. Fellat , R. Fellat , A. Bensouda , A. Chaib , S. Moughil
{"title":"Promising long-term surgical outcomes of aortic valve replacement in patients with important isolated aortic regurgitation and severe left ventricular dysfunction","authors":"A. Soufiani , Z. Agoumy , M. Tribak , S. El Mhadi , Z. Fassi Fehri , H. Chraibi , L. Bakamel , O. Soussi , H. El Assili , K. Berrag , J. Raoui , FZ Hattab , Z. Idrissi , S. Essebany , H. Leghlimi , F. Lachhab , N. Fellat , R. Fellat , A. Bensouda , A. Chaib , S. Moughil","doi":"10.1016/j.ancard.2024.101859","DOIUrl":"10.1016/j.ancard.2024.101859","url":null,"abstract":"<div><h3>Background</h3><div>Surgical management of patients with severe aortic regurgitation (AR) in the setting of significantly impaired left ventricle (LV) function generally carries very high operative risk. The aim of this study is to assess the short and long-term outcomes of aortic valve replacement (AVR) in a selected young Moroccan population.</div></div><div><h3>Materiel and methods</h3><div>This is a retrospective study between January 2008 and June 2022 including all patients who underwent AVR for massive isolated AR with an LV ejection fraction EF ≤35%.</div></div><div><h3>Results</h3><div>In this center, a total of 3820 patients were operated for valvular disease, from which 110 had important AR. Overall, 42 patients of 110 patients had an LV ejection fraction≤35%, and benefited from AVR. Rheumatic cause was predominant (50%). Preoperative characteristics find an average age of 46.3 ±14.4 years with male prevalence. Only two deaths are noted in the immediate postoperative period. At the 15 years follow-up, the survival was 86.8%. Clinical improvement was present in the majority of patients. The mean LVEF post-AVR has increased by an average of 16% with proof of reverse remodeling.</div></div><div><h3>Conclusions</h3><div>In this series, patients benefited largely from AVR with good postoperative outcomes. The global operative mortality was acceptable (4.7%). The long-term survival (86.8%) was better than that described in the western series. Therefore, our results should encourage a surgical approach for those patients.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"Article 101859"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yassine Rabab, Ndao Serigne Cheikh Tidiane, Ka Mame Madjiguene, Mboup Waly Niang, Fall Aissatou, Dia Khadidiatou, Mboup Mouhamed Chérif
{"title":"Coronarographie et étiologies de l'insuffisance cardiaque à fraction d’éjection ventriculaire gauche altérée au Sénégal","authors":"Yassine Rabab, Ndao Serigne Cheikh Tidiane, Ka Mame Madjiguene, Mboup Waly Niang, Fall Aissatou, Dia Khadidiatou, Mboup Mouhamed Chérif","doi":"10.1016/j.ancard.2024.101860","DOIUrl":"10.1016/j.ancard.2024.101860","url":null,"abstract":"<div><h3>Introduction</h3><div>Heart failure is a major public health problem because of the number and duration of hospitalizations. Patients with heart failure may have mixed etiologies that are not mutually exclusive, and etiologies vary between high-income and developing countries. The aim of our work was to study the contribution of coronary angiography in the etiological investigation of heart failure with impaired LVEF in the cardiology department of HPD.</div></div><div><h3>Methodology</h3><div>This was a descriptive and analytical cross-sectional study with retrospective data collection on 103 patients hospitalized in the cardiology department of DAKAR's Hospital Principal presenting with heart failure with impaired LVEF and who underwent coronary angiography from January 2019 to December 2022.</div></div><div><h3>Results</h3><div>Our study included 103 patients with a clear male predominance 79.6% and a sex ratio of 3.7. Their mean age was 64±13.5 years. Diabetes was prevalent at 24.3% (<em>p</em>=0.033). All patients had impaired segmental and/or global left ventricular kinetics. Mean ejection fraction was 28.1±6.8. The right radial route was predominantly used 83.7% of the time, and there were no procedural incidents or accidents. Diabetes was significantly associated with coronary involvement (<em>p</em>=0.033). Coronary angiography was normal in 37.8% of patients and showed tri-truncular lesions in 19.4% of patients and bi-truncular lesions in 17.4%.</div><div>We found 91 significant lesion and 67 non-significant lesion. A total of 41 patients had ischemic heart disease, equivalent to 39.8%.</div></div><div><h3>Conclusion</h3><div>Our study shows that ischemic heart disease plays an important role in the etiology of heart failure with impaired LVEF, and that coronary angiography should be performed routinely.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"Article 101860"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sommaire","authors":"","doi":"10.1016/S0003-3928(25)00010-1","DOIUrl":"10.1016/S0003-3928(25)00010-1","url":null,"abstract":"","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"Article 101871"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}