I. Taleb, A. Dozier, H. Raddaoui, K. Hembert, A. Sghaier, S. Mainil, F. Favata, J. Fleuriet, C. Seunes, A. Ouadah, C. Le Goffic, M. Meghnem, M. Verhaeghe, P. Le Tadic, J. Cardot, C. Diharce, L. Velain, M. Dangbegnon, E. Bearez, M. Randriamora, G. Hannebicque
{"title":"Registre Endocarras : incidence, profil et mortalité de l’endocardite infectieuse entre 2013 et 2024 dans un hôpital français sans service de chirurgie cardiaque sur site","authors":"I. Taleb, A. Dozier, H. Raddaoui, K. Hembert, A. Sghaier, S. Mainil, F. Favata, J. Fleuriet, C. Seunes, A. Ouadah, C. Le Goffic, M. Meghnem, M. Verhaeghe, P. Le Tadic, J. Cardot, C. Diharce, L. Velain, M. Dangbegnon, E. Bearez, M. Randriamora, G. Hannebicque","doi":"10.1016/j.ancard.2026.102051","DOIUrl":"10.1016/j.ancard.2026.102051","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite improvements in diagnostic and therapeutic strategies, infective endocarditis (IE) remains a life-threatening disease with high in-hospital mortality. However, most contemporary data originate from tertiary referral centres with on-site cardiac surgery. The recruitment bias may lead to an underestimation of the true morbidity and mortality of IE in general hospitals.</div></div><div><h3>Objective</h3><div>The ENDOCARRAS register aimed to determine the epidemiological characteristics and prognosis of patients with IE admitted to the Arras hospital center, French care facility with 1600 beds including a cardiology and intensive care service without on-site cardiac surgery.</div></div><div><h3>Method</h3><div>From January 1st, 2003, to December 31st, 2024, all pts with a definite or possible diagnosis of IE according to modified Duke criteria (applicable at the time of admission) were included. Demographic characteristics, comorbidities, microbiology, imaging modalities, therapeutic strategies, and quality-of-care indicators were collected. Primary endpoints were in-hospital and one-year all-cause mortality. Multivariable logistic regression analyses were performed to identify independent predictors of in-hospital death.</div></div><div><h3>Results</h3><div>Three hundred and six pts were included. The mean age was 71<!--> <!-->±<!--> <!-->13 years, and 59.5% were male. IE was definite in 75% of cases, involving native valves (68.3%), prosthetic valves (20.6%), or intracardiac devices (12.7%). The most frequently identified pathogens were <em>aureus Staphylococci</em> (40.2%), oral streptococci (13%), and enterococci (12.7%). Transoesophagal echocardiography, positron-emission tomography and cardiac CT were performed respectively in 74%, 36.4%, and 4.6% of points. Embolic events occurred in 46.7% of points. Comorbidities included heart failure (36.6%), chronic kidney disease stage 4/5 (19.3%), and bedridden status (17.6%). Cardiac surgery was performed in only 22.9% of pts and contraindicated in 34%. In-hospital and 1-year mortality rates were 27.8 and 40%, respectively. In hospital mortality rise dramatically to 41.5% in patients older than 75 years, compared to 18.6% in younger patients (<em>P</em> <!--><<!--> <!-->0.001). Age<!--> <!-->><!--> <!-->75 years and the absence of advanced cardiac imaging independently predicted mortality. Over time, IE incidence increased while surgical rates declined.</div></div><div><h3>Conclusion</h3><div>In this real-world monocentric registry spanning 11 years, IE appears increasingly frequent, with persistently high in-hospital mortality and low utilization of cardiac surgery, particularly among older points with severe comorbidities.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102051"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148560762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Roussel, T. Cuisset, J. Boyer, E. Bressollette, B. Seguy, B. Honton, N. Amabile, P. Deharo
{"title":"Réactivité plaquettaire intracoronaire lors d’une angioplastie coronaire assistée par athérectomie : une étude prospective","authors":"T. Roussel, T. Cuisset, J. Boyer, E. Bressollette, B. Seguy, B. Honton, N. Amabile, P. Deharo","doi":"10.1016/j.ancard.2026.102058","DOIUrl":"10.1016/j.ancard.2026.102058","url":null,"abstract":"<div><h3>Background</h3><div>Rotational atherectomy (RA) and orbital atherectomy (OA) are widely used for plaque modification in severely calcified coronary lesions. Historical concerns have suggested that high rotational speeds may induce platelet activation during percutaneous coronary intervention (PCI), but data in the context of contemporary procedural strategies and dual antiplatelet therapy (DAPT) remain limited.</div></div><div><h3>Methods</h3><div>In this prospective single-centre study, 59 patients with chronic coronary syndrome undergoing atherectomy-assisted PCI were enrolled. RA was performed with high-speed runs (≈180,000<!--> <!-->rpm) combined with low-speed exploratory runs (≈110,000<!--> <!-->rpm) while OA used systematic low-speed runs (80,000<!--> <!-->rpm) and selective high-speed runs (120,000<!--> <!-->rpm). All patients received aspirin and a P2Y12 inhibitor before PCI. Platelet reactivity was assessed at predefined procedural time points using the VASP (vasodilator-stimulated phosphoprotein) assay and aggregation tests with arachidonic acid (AA) and adenosine diphosphate (ADP).</div></div><div><h3>Results</h3><div>Among 60 patients (mean age 74.1 years, 72.8% male), 38 underwent RA and 22 OA. No significant increase in platelet reactivity was observed between baseline and final measurements for any test (AA: <em>P</em> <!-->=<!--> <!-->0.174; ADP: <em>P</em> <!-->=<!--> <!-->0.437; VASP: <em>P</em> <!-->=<!--> <!-->0.071), with values remaining stable or slightly decreased. Subgroup analyses showed consistent results for RA and OA, with no significant variation by technique. Procedural kinetics over four time points showed no transient elevation of platelet reactivity at any stage. All procedures were angiographically successful.</div></div><div><h3>Conclusion</h3><div>Under contemporary DAPT, atherectomy-assisted PCI with RA or OA does not induce platelet hyperreactivity. These results support the biological safety of modern atherectomy strategies, although their mechanistic nature warrants confirmation in larger outcome-driven studies.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102058"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148766551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Une nouvelle ère pour les Annales de cardiologie","authors":"H. Benamer","doi":"10.1016/j.ancard.2026.102056","DOIUrl":"10.1016/j.ancard.2026.102056","url":null,"abstract":"","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102056"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La stimulation cardiaque physiologique : vers un nouvel eldorado de la stimulation cardiaque ?","authors":"C. Coquard","doi":"10.1016/j.ancard.2026.102060","DOIUrl":"10.1016/j.ancard.2026.102060","url":null,"abstract":"","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102060"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Barsoum, D. Bazin, B. Grine, R. Geha, F. Walylo, H. Colboc
{"title":"Structural degradation of a rotational atherectomy burr following treatment of a massively calcified coronary lesion: Insights from scanning electron microscopy","authors":"P. Barsoum, D. Bazin, B. Grine, R. Geha, F. Walylo, H. Colboc","doi":"10.1016/j.ancard.2026.102057","DOIUrl":"10.1016/j.ancard.2026.102057","url":null,"abstract":"<div><h3>Background</h3><div>Rotational atherectomy is an established strategy for the treatment of severely calcified coronary lesions. Although reduced burr efficiency is not uncommon during complex procedures, the structural changes responsible for this phenomenon have not been investigated following rotational atherectomy of native coronary lesions.</div></div><div><h3>Case</h3><div>In a patient undergoing rotational atherectomy for a massively calcified native coronary lesion, we encountered failure of the burr to cross the lesion despite preserved rotational speed. Macroscopic examination suggested surface alteration of the burr. Replacement with a new burr resulted in immediate lesion crossing. To investigate the underlying mechanism, the surface of a new burr was compared with that of a clinically used burr using high-resolution field-emission scanning electron microscopy (FE-SEM).</div></div><div><h3>Findings</h3><div>FE-SEM demonstrated marked thinning of the cobalt binding matrix and multiple cavities indicating loss of diamond particles. In contrast, the remaining exposed diamond particles showed no obvious structural damage. These observations indicate that progressive degradation of the cobalt matrix, rather than damage of the diamond particles themselves, is the most likely mechanism responsible for reduced abrasive performance of the rotational atherectomy burr.</div></div><div><h3>Conclusions</h3><div>This report provides the first ultrastructural evidence of rotational atherectomy burr degradation following treatment of a severely calcified native coronary lesion. FE-SEM provides novel mechanistic insight into the progressive loss of the burr's abrasive performance, offering a plausible explanation for a situation frequently encountered by interventional cardiologists in which plaque modification becomes ineffective. Recognition of this mechanism may help operators identify burr wear and consider its replacement.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102057"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sommaire","authors":"","doi":"10.1016/S0003-3928(26)00074-0","DOIUrl":"10.1016/S0003-3928(26)00074-0","url":null,"abstract":"","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102069"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Weizman, T. Dejean, G. Prati, M. Hauguel-Moreau
{"title":"Ballon actif : une véritable révolution dans le traitement des lésions coronaires ?","authors":"O. Weizman, T. Dejean, G. Prati, M. Hauguel-Moreau","doi":"10.1016/j.ancard.2026.102054","DOIUrl":"10.1016/j.ancard.2026.102054","url":null,"abstract":"","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102054"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148629196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Angoran Regnier, M.P. N’Cho-Mottoh, A. Ekou, I. Garba, A. Coulibaly, A.R. N’Guetta
{"title":"Apport de l’angiographie coronaire par tomodensitométrie dans le dépistage des anomalies de naissance des artères coronaires : étude rétrospective de 422 examens dans un pays de l’Afrique de l’Ouest","authors":"I. Angoran Regnier, M.P. N’Cho-Mottoh, A. Ekou, I. Garba, A. Coulibaly, A.R. N’Guetta","doi":"10.1016/j.ancard.2026.102053","DOIUrl":"10.1016/j.ancard.2026.102053","url":null,"abstract":"<div><h3>Introduction</h3><div>Anomalous origins of coronary arteries (AOCA) represent the second leading cause of sudden cardiac death in young individuals. Diagnosis is challenging because symptoms often mimic classic ischemia or present as MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries). This study aimed to evaluate the prevalence and malignancy criteria of AOCA in patients undergoing coronary angiography in Abidjan.</div></div><div><h3>Materials and methods</h3><div>A retrospective study was conducted in Abidjan, Côte d’Ivoire, analyzing 422 coronary CT angiograms performed between May 2023 and December 2025. The protocol included calcium scoring and angiographic acquisition to analyze the arterial course and wall. Post-processing was performed on a dedicated workstation. Investigated malignancy criteria included ectopic origin, inter-arterial course, acute ostial angulation, intramural course, and the presence of a slit-like ostium.</div></div><div><h3>Results</h3><div>The prevalence of AOCA was 1.65% (7 cases). The mean age was 51.4<!--> <!-->±<!--> <!-->12 years. Chest pain was the primary reason for consultation (85.71% of cases). Calcium scores were zero in 85.71% of patients. The most frequent anomaly was the right coronary artery arising from the left sinus (<em>n</em> <!-->=<!--> <!-->3; 42.85%). There were also two (2) cases (28.57%) of ectopic right coronary origin from the aorta and two (2) cases of ectopic origin of the left anterior descending artery. A high-risk inter-arterial course was identified in 85.71% of patients.</div></div><div><h3>Conclusion</h3><div>Coronary CT angiography is essential for the anatomical characterization and risk stratification of AOCA. In the African context, the increasing accessibility of coronary CT scanning provides a major opportunity for early detection and primary prevention of sudden cardiac death.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102053"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148468464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PCI for in-stent restenosis of an anomalous right coronary artery","authors":"Z. Laraichi, H. Benamer","doi":"10.1016/j.ancard.2026.102061","DOIUrl":"10.1016/j.ancard.2026.102061","url":null,"abstract":"<div><div>Coronary angioplasty for congenital anomalies of the coronary arteries (ANOCOR) remains a technically demanding procedure due to the difficulties associated with selective cannulation of the coronary ostium and achieving adequate support for the guide catheter. We report a case of in-stent restenosis in a proximal connection anomaly of the right coronary artery arising from the left coronary sinus, which was successfully treated using an innovative telescopic technique. A 63-year-old female patient, presenting with multiple cardiovascular risk factors and having previously undergone angioplasty of this right coronary artery, was referred for recurrent angina and exertional dyspnea. Myocardial scintigraphy revealed ischemia of the inferior wall, and coronary angiography demonstrated significant in-stent restenosis of the proximal and middle segments of the right coronary artery. Angioplasty was performed via the right femoral approach using a 7 Fr introducer. Selective intubation of the coronary ostium was achieved using a telescopic configuration consisting of inserting a 5 Fr internal mammary guide catheter within a 7 Fr 3.5 Extra Backup (EBU) guide catheter, allowing for optimal coaxial alignment and satisfactory support. This strategy allowed for lesion preparation followed by the implantation of two drug-eluting stents, resulting in an excellent angiographic outcome and significant clinical improvement.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"75 4","pages":"Article 102061"},"PeriodicalIF":0.3,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}