Revista argentina de endocrinologia y metabolismo最新文献_第2页

Inclusion of avocado (Persea americana) seeds in the diet to improve carbohydrate and lipid metabolism in rats 在饮食中加入鳄梨种子以改善大鼠的碳水化合物和脂质代谢

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-07-01 Epub Date: 2017-08-12 DOI: 10.1016/j.raem.2017.07.005

Uzukwu Emmanuel Uchenna , Amal Bakr Shori , Ahmad Salihin Baba

引用次数: 18

Incidentalomas paratiroideos: un nuevo diagnóstico, un nuevo problema. Prevalencia en Argentina 甲状旁腺偶然瘤:新诊断，新问题。阿根廷流行率

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-07-01 Epub Date: 2017-08-12 DOI: 10.1016/j.raem.2017.07.003

José Luis Mansur, Laura Ivankovic, Fabricio Torchiari

{"title":"Incidentalomas paratiroideos: un nuevo diagnóstico, un nuevo problema. Prevalencia en Argentina","authors":"José Luis Mansur, Laura Ivankovic, Fabricio Torchiari","doi":"10.1016/j.raem.2017.07.003","DOIUrl":"10.1016/j.raem.2017.07.003","url":null,"abstract":"<div><p>Parathyroid incidentalomas (PI) were first described as intraoperative findings and then in ultrasound thyroid scan studies. Few studies have been performed to investigate this, so their incidence is unclear. Moreover, the presence of a hypo-echogenic image in parathyroid topography may also be thyroid or lymphatic tissue. A retrospective evaluation was performed on the seven-year clinical records of patients in whom a PI was diagnosed during a thyroid ultrasound scan. PI was diagnosed in 24 patients (4.0%). Twenty one patients had autoimmune hypothyroidism and 3 patients had thyroid nodules. In 10 cases the lesion was unique, and in 14 cases there were two or more lesions. During follow-up, ultrasound was repeated in 13 patients, and all showed findings. Serum calcium and PTH were normal in 23 patients, but in one of them, with an image of a lesion of 6mm, PTH was slightly elevated, with normal serum calcium. Later, hypercalcaemia was detected and a parathyroid adenoma was diagnosed. The incidence of PI seems to be increasing, with our rate of 4% of compatible images (without confirming the parathyroid origin of the lesion) is higher than that reported in the few existing publications on the subject. Many patients with PI may not present with biochemical abnormalities, but as our experience shows, these lesions may represent the first stage of primary hyperparathyroidism; therefore careful follow-up is advisable.</p></div>","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"54 3","pages":"Pages 136-139"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.raem.2017.07.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46442610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fe de errores de “Polimorfismos del receptor D2” “D2受体多态性”错误Fe

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-07-01 Epub Date: 2017-08-13 DOI: 10.1016/j.raem.2017.07.008

María Eugenia Céspedes

引用次数: 0

Métodos de tiroglobulina de primera y segunda generación: su utilidad en pacientes con cáncer diferenciado de tiroides 第一代和第二代甲状腺球蛋白的方法:它在分化型甲状腺癌患者中的应用

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-07-01 Epub Date: 2017-07-06 DOI: 10.1016/j.raem.2017.05.002

Isabel Teres , Graciela Astarita , Viviana Mesch , Graciela Mosquera Filoso , María Paula Esteban , Andrea Kozac , Natalia Blanco Hirota , Mirta Gurfinkiel , Ana María Sequera , Patricia Pagano , Mónica Saavedra , María José Iparraguirre , Marta Torres , Patricia Rodríguez , Patricia Otero , Patricia Glikman

{"title":"Métodos de tiroglobulina de primera y segunda generación: su utilidad en pacientes con cáncer diferenciado de tiroides","authors":"Isabel Teres , Graciela Astarita , Viviana Mesch , Graciela Mosquera Filoso , María Paula Esteban , Andrea Kozac , Natalia Blanco Hirota , Mirta Gurfinkiel , Ana María Sequera , Patricia Pagano , Mónica Saavedra , María José Iparraguirre , Marta Torres , Patricia Rodríguez , Patricia Otero , Patricia Glikman","doi":"10.1016/j.raem.2017.05.002","DOIUrl":"10.1016/j.raem.2017.05.002","url":null,"abstract":"<div><p>Differentiated thyroid cancer (DTC) is the most common endocrine cancer (tumour) and its incidence has risen in the past decades. Its follow-up includes measuring serum thyroglobulin (Tg), performing neck ultrasound and a diagnostic whole-body scan. Tg assays have evolved with time. At present immunoassays for Tg are classified as 1st and 2nd generation assays (1st G and 2nd G). 2nd G assays show an adequate (good) precision at levels close to 0.1ng/ml and 1st G assays at levels close to 1ng/ml. The literature shows that for low risk patients on levothyroxine treatment, who undetectable levels by 2ªG assays can avoid the stimulation test performed by thyroid hormone withdrawal or after recombinant human TSH, due to better sensitivity. However, due to lower specificity, detectable levels do not confirm the presence of disease (tumour), and should be confirmed. To optimise the clinical usefulness of the test, cut-off values specific for population and method should be used, instead of functional sensitivity or quantification limit. Critical issues for measuring Tg are discussed, such as non-harmonisation of methods, and interferences, mainly by anti-thyroglobulin antibodies (ATg). 1st and 2nd G assays are less useful in presence of ATg, and follow up of such patients is limited. Consensus between physicians and the laboratory on technical issues and interpretation criteria of Tg values is of outmost importance in the follow-up of DTC patients.</p></div>","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"54 3","pages":"Pages 101-108"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.raem.2017.05.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48852744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

La tormentosa relación entre las grasas y el desarrollo de la diabetes mellitus de tipo 2: actualizado. Parte 1 脂肪与2型糖尿病发展之间的风暴关系:更新。第1部分

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-07-01 Epub Date: 2017-07-02 DOI: 10.1016/j.raem.2017.06.001

José Esteban Costa Gil , Eduardo Spinedi

{"title":"La tormentosa relación entre las grasas y el desarrollo de la diabetes mellitus de tipo 2: actualizado. Parte 1","authors":"José Esteban Costa Gil , Eduardo Spinedi","doi":"10.1016/j.raem.2017.06.001","DOIUrl":"https://doi.org/10.1016/j.raem.2017.06.001","url":null,"abstract":"<div><p>A review is presented on a functional relationship between fat and carbohydrate metabolism and inter-dependence from the traditional concepts of glucose-fatty acids cycle (Randle), and from the insulin resistance portal hypothesis up to the new aspects on brown and beige adipocytes. Emphasis is placed on the normal function of an endocrine pattern, in which its malfunction is the key in the pathophysiology of these conditions: the adipoinsular axis, with a functional link with the hypothalamic-pituitary-adrenal axis, which involves 2adipogenic hormones (insulin and glucocorticoid). This has an influence on the development of omental peri-visceral fat, with severe metabolic consequences. A discussion is also presented on the concept of ectopic fat on non-adipose tissues that results in the incapacity of fatty tissue for storing lipids and the considerations about the endocrine activity of adipocyte producing substances that influence several mechanisms that could result in insulin resistance (leptin, adiponectin, TNF-α, resistin, etc.). New aspects are considered regarding the decrease in the oxidative capacity in the mitochondrial respiratory chain, and the re-birth of the concept of <em>de novo</em> lipogenesis that increases the storing of intra-cellular fat. In non-adipose tissues there are small intra-cellular fat quantities for essential functions, but lipid overloading leads to cell dysfunction (lipo-toxicity) and death (lipo-apoptosis). The stormy relationship between fat and Langerhans’ Islets goes beyond the functional effort as consequence of peripheral insulin-resistance and the pancreatic beta cell suffers a direct lipid (or derivatives) functional effect. Without insulin deficiency diabetes does not appear.</p></div>","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"54 3","pages":"Pages 109-123"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.raem.2017.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136901263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Riesgo dinámico en pacientes con cáncer diferenciado de tiroides no ablacionados 非消融性分化甲状腺癌患者的动态风险

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-04-01 Epub Date: 2017-05-18 DOI: 10.1016/j.raem.2017.04.001

Erika Abelleira, Fernanda Bueno, Anabella Smulever, Fabián Pitoia

{"title":"Riesgo dinámico en pacientes con cáncer diferenciado de tiroides no ablacionados","authors":"Erika Abelleira, Fernanda Bueno, Anabella Smulever, Fabián Pitoia","doi":"10.1016/j.raem.2017.04.001","DOIUrl":"10.1016/j.raem.2017.04.001","url":null,"abstract":"<div><p>The therapeutic approach and the follow-up of patients with differentiated thyroid cancer (DTC) is currently individualised according to the risk of recurrence, with a lower tendency to perform remnant ablation (RA) in patients with low risk of recurrence. While response to therapy assessment has been validated for DTC patients treated by total thyroidectomy (TT) and RA, it has not been widely confirmed in patients treated with TT without RA. The aims of this study were to describe the characteristics of the population of patients treated with TT without RA, and to validate the response to therapy. The study included 88 patients followed-up for at least 12 months after surgery. In the entire cohort, 87.9% were female and the mean age was 47.5 years old. Based on the Argentine Intersociety Consensus, 97.7% and 2.3% were classified as low risk and intermediate risk of recurrence, respectively. Patients had an initial excellent response to treatment in 73% of cases, with a disease-free status at the end of follow-up of 85.5%. A minority of patients (1%) presented with an initial structural incomplete response, which was similar at the end of follow-up (1%). On the other hand, 26% of the patients had an initial indeterminate response, although only 13.5% remained with this response at the end of follow-up. These results validate the responses to treatment in DTC patients treated with TT without RA as an effective tool for the dynamic risk stratification. Patients appropriately selected who did not receive RA have an excellent outcome, with a low frequency of structural incomplete response, even lower than that observed in low risk ablated patients.</p></div>","PeriodicalId":78598,"journal":{"name":"Revista argentina de endocrinologia y metabolismo","volume":"54 2","pages":"Pages 69-75"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.raem.2017.04.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41943591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Hipofisitis linfoplasmocitaria con expresión de IgG4 淋巴浆细胞性脑下垂体炎伴IgG4表达

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-04-01 Epub Date: 2017-02-22 DOI: 10.1016/j.raem.2017.01.001

Gabriela Alejandra Sosa

引用次数: 2

Metástasis a distancia en cáncer diferenciado de tiroides: diagnóstico y tratamiento 分化甲状腺癌的远程转移:诊断与治疗

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-04-01 Epub Date: 2017-06-03 DOI: 10.1016/j.raem.2017.05.001

Angelica Schmidt, Graciela Cross, Fabián Pitoia

引用次数: 4

Enfermedad no tiroidea 非甲状腺疾病

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-04-01 Epub Date: 2017-04-28 DOI: 10.1016/j.raem.2017.03.002

Johanna Rosenfarb, M. Cristina Faingold, Gabriela Brenta

引用次数: 2

Masa selar, no siempre un adenoma: presentación de 3 casos clínicos 闭塞肿块，并不总是腺瘤:3例临床病例的呈现

Revista argentina de endocrinologia y metabolismo Pub Date : 2017-04-01 Epub Date: 2017-05-30 DOI: 10.1016/j.raem.2017.03.001

Noelia Barrera Olarte, Romina Esparza, Cecilia Hurtado, Nicole Lemaitre, Mariela Luna, Ronaldo Oliszewski, Mariel Soto, Teresa Torrado

引用次数: 0