Incidentalomas paratiroideos: un nuevo diagnóstico, un nuevo problema. Prevalencia en Argentina

José Luis Mansur, Laura Ivankovic, Fabricio Torchiari
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Abstract

Parathyroid incidentalomas (PI) were first described as intraoperative findings and then in ultrasound thyroid scan studies. Few studies have been performed to investigate this, so their incidence is unclear. Moreover, the presence of a hypo-echogenic image in parathyroid topography may also be thyroid or lymphatic tissue. A retrospective evaluation was performed on the seven-year clinical records of patients in whom a PI was diagnosed during a thyroid ultrasound scan. PI was diagnosed in 24 patients (4.0%). Twenty one patients had autoimmune hypothyroidism and 3 patients had thyroid nodules. In 10 cases the lesion was unique, and in 14 cases there were two or more lesions. During follow-up, ultrasound was repeated in 13 patients, and all showed findings. Serum calcium and PTH were normal in 23 patients, but in one of them, with an image of a lesion of 6 mm, PTH was slightly elevated, with normal serum calcium. Later, hypercalcaemia was detected and a parathyroid adenoma was diagnosed. The incidence of PI seems to be increasing, with our rate of 4% of compatible images (without confirming the parathyroid origin of the lesion) is higher than that reported in the few existing publications on the subject. Many patients with PI may not present with biochemical abnormalities, but as our experience shows, these lesions may represent the first stage of primary hyperparathyroidism; therefore careful follow-up is advisable.

甲状旁腺偶然瘤:新诊断,新问题。阿根廷流行率
甲状旁腺偶发瘤(PI)首先被描述为术中发现,然后在超声甲状腺扫描研究。很少有研究对此进行调查,因此其发病率尚不清楚。此外,甲状旁腺地形上的低回声图像也可能是甲状腺或淋巴组织。对甲状腺超声扫描中诊断为PI的患者的7年临床记录进行回顾性评估。24例(4.0%)被诊断为PI。自身免疫性甲状腺功能减退21例,甲状腺结节3例。10例病变是独特的,14例有两个或两个以上的病变。在随访中,13例患者重复超声检查,均有发现。23例患者血清钙、甲状旁腺素正常,其中1例病变图像为6mm,甲状旁腺素轻度升高,血清钙正常。后来发现高钙血症,并诊断为甲状旁腺瘤。PI的发病率似乎在增加,我们的4%的相容图像(未确认病变的甲状旁腺起源)的发生率高于少数现有出版物中关于该主题的报道。许多PI患者可能不存在生化异常,但根据我们的经验,这些病变可能代表原发性甲状旁腺功能亢进的第一阶段;因此,建议仔细跟进。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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