Algal Research-Biomass Biofuels and Bioproducts最新文献

{"title":"Compliance assessment oriented microcystin prediction: A Bayesian adaptive LASSO Tobit quantile regression approach","authors":"Fan Qu ,&nbsp;Lingjing Lin ,&nbsp;Changbo Qin ,&nbsp;Fuli Peng ,&nbsp;Runzi Wang ,&nbsp;Nengwang Chen ,&nbsp;Gang Zhao ,&nbsp;Wentao Lu ,&nbsp;Zhongyao Liang","doi":"10.1016/j.algal.2025.104026","DOIUrl":"10.1016/j.algal.2025.104026","url":null,"abstract":"<div><div>Microcystin has been one of major contaminants impacting health of aquatic ecosystems and threatening human health. The development of drivers-microcystin relationship is of vital importance to microcystin management. However, current practices often focused on the mean response of microcystin concentration and cannot meet the requirement of percentile-based compliance assessment. Despite of many informative studies on the development of drivers–microcystin relationship, there remains a gap between the relationship development and the percentile-based compliance assessment of microcystin concentration. In this study, Bayesian adaptive LASSO Tobit quantile regression (BALTQR) model was introduced to environmental and ecological studies for the first time. The model is specially designed for the prediction of left-censored response variable. We applied the BALTQR model to develop the drivers–microcystin relationship of lakes across the US continent. Based on the results of parameters estimation, Chlorophyll <em>a</em> (CHL), pH, and water temperature (WT) were identified as key drivers to the microcystin concentration. We found that CHL was approximate the same important as pH and both of them had positive effects on the microcystin concentration at all the five regression quantiles. WT was relatively less important and had a surprisingly negative effect at the 0.7, 0.8, and 0.9 regression quantiles. We demonstrated that the BALTQR model successfully established the linkage between the development of drivers–microcystin relationship and the compliance assessment of microcystin concentration. We further revealed important implications of these findings to microcystin management. We believed that the BALTQR model has great potential of generalization to model other left-censored response variable in environmental and ecological studies.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104026"},"PeriodicalIF":4.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microwave-assisted depolymerization of hydrothermally extracted carrageenan from Chondrus crispus","authors":"Milena Álvarez-Viñas,&nbsp;María Dolores Torres,&nbsp;Herminia Domínguez","doi":"10.1016/j.algal.2025.104046","DOIUrl":"10.1016/j.algal.2025.104046","url":null,"abstract":"<div><div>Carrageenans, extracted from red macroalgae, have demonstrated to present a wide variety of biological activities, such as antitumor activity, which could be enhanced upon depolymerization techniques. For that reason, this work dealt with the extraction of oligocarrageenans and carrageenan from <em>Chondrus crispus</em> by autohydrolysis, and the evaluation of microwave-assisted depolymerization to evaluate the improvement of its antitumor activity. This activity may be conditioned by the extraction method, the degree of sulfation, or the degree of depolymerization. Hence, these parameters were assessed, revealing an increase on the soluble sulfate content and lower molecular weight after 25 min of processing at 140 or 160 °C. In addition, the extract viscosity was lowered from 10,000 to 100 Pa·s, suggesting a positive effect of the microwave-assisted depolymerization and an enhanced bioavailability. The antitumor activity of the depolymerized oligocarrageenan and carrageenan was studied against human ovarian carcinoma cell line, reaching up to 92 % of cell growth inhibition (IC₅₀ = 84 mg/L).</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104046"},"PeriodicalIF":4.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Sargassum beds on carbon sequestration and microbial community structure in the adjacent sediment cores","authors":"Lili Xu ,&nbsp;Xian Sun ,&nbsp;Zhiwei Liu ,&nbsp;Ligong Zou ,&nbsp;Zhili He ,&nbsp;Juan Ling ,&nbsp;Linjian Ou ,&nbsp;Bin Jiang ,&nbsp;Yufeng Yang ,&nbsp;Qing Wang","doi":"10.1016/j.algal.2025.104045","DOIUrl":"10.1016/j.algal.2025.104045","url":null,"abstract":"<div><div>Seaweed detritus transported to the deep sea is an important component of marine carbon sequestration. However, the impacts of seaweed decomposition on adjacent sediments and the response mechanisms of microbial communities are still unclear. In this study, we analyzed the changes in carbon and nitrogen contents, the molecular composition of dissolved organic matter (DOM), and microbial communities in three sediment cores at different distances (1, 2, and 3 km, respectively) from <em>Sargassum</em> beds in Weizhou Island coastal waters, China. The results show that the impact of <em>Sargassum</em> on sediment cores exhibits strong spatial heterogeneity, with more aromatic-like and tannin molecules found at the nearest site (S1). Compared to the other two sediment cores, the microbial community composition of S1 is significantly different. The homogeneous selection dominates the assembly of the microbial community at S1. In addition, the input of decomposing organic matter from <em>Sargassum</em> contributed to a significant increase in the abundance of functional genes related to carbon and nitrogen decomposition at S1, leading to a significant decrease in TOC and TN content in the sediments. Our study demonstrated that the decomposition of <em>Sargassum</em> increased the sources and molecular species of organic matter in the adjacent sediments and stimulated microbial decomposition of organic matter. Strengthening the protection of <em>Sargassum</em> beds contributes to improving biodiversity and promoting the marine carbon and nitrogen cycles.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104045"},"PeriodicalIF":4.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collection of rich microalgae from textile wastewater and utilized for hydrogen production via hydrothermal gasification route: Performance study","authors":"Manzoore Elahi M. Soudagar ,&nbsp;Aman Sharma ,&nbsp;R. Srinivasan ,&nbsp;Nagabhooshanam Nagarajan ,&nbsp;Vinayagam Mohanavel ,&nbsp;M. Ravichandran ,&nbsp;Manikandan Ayyar ,&nbsp;Sami Al Obaid ,&nbsp;Sulaiman Ali Alharbi","doi":"10.1016/j.algal.2025.104052","DOIUrl":"10.1016/j.algal.2025.104052","url":null,"abstract":"<div><div>In this investigation, textile wastewater was treated in an open raceway pond to promote algae growth for biomass production. Various environmental factors initially hindered the growth of algae. However, the growth rate was improved by integrating titanium dioxide (TiO₂) nanoparticles at different concentrations. The concentrations tested included 0, 2, 4, and 6 % by weight in the wastewater. The study analyzed specific growth rates and biomass production resulting from these variations. Additionally, the cultivated algae were utilized in hydrothermal gasification for hydrogen production. This gasification process was conducted under a residence time of 30 min and a pressure of 200 bar, with gasification temperatures of 350, 450, 550, and 650 °C. Gasification efficiency was further enhanced using a potassium hydroxide (KOH) catalyst. At a higher TiO₂ nanoparticle concentration of 6 %, the specific growth rate and biomass production achieved were approximately 67.9 % and 75.3 %, respectively. In the hydrothermal gasification process, the gasification efficiency (GE), hydrogen selectivity, and higher heating value (HHV) were measured at about 81.5 %, 94.6 %, and 31.5 MJ/Nm³ at 650 °C with the 5 % of KOH catalyst, showing a significant improvement compared to conditions without a catalyst.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104052"},"PeriodicalIF":4.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indigenous microalgae consortium for producing safe reclaimed water and bio-fertilisers. Batch tests for replication, scale-up and legislative analysis","authors":"J. González-Camejo ,&nbsp;A.L. Eusebi ,&nbsp;F. Fatone ,&nbsp;M. Pachés","doi":"10.1016/j.algal.2025.104043","DOIUrl":"10.1016/j.algal.2025.104043","url":null,"abstract":"<div><div>This study aimed to assess the potential of using indigenous microalgae to treat sewage and produce safe reclaimed water and bio-fertilisers. Cultivation tests were conducted using sole or mixed sewage streams combining primary effluent (PSE), secondary effluent (SSE), and centrate (CEN) to identify the most suitable substrate. Overall, higher nitrogen removal rates, biomass productivity, and carbon biofixation were observed when microalgae were cultivated in PSE compared to SSE, with values ranging from 2.1 to 12.1 mgN·L⁻¹·d⁻¹, 18 to 52 mgVSS·L⁻¹·d⁻¹ (20–53 mgTSS·L⁻¹·d⁻¹), and 10.7 to 27.0 mgCO₂·L⁻¹·d⁻¹, respectively. Adding centrate improved microalgae performance by increasing the availability of nutrients and inorganic carbon, but when 30 % centrate was added, detrimental effects were observed. The costs of the microalgae-based treatment process ranged from 0.081 to 0.098 €·m⁻³, which is significantly lower than those of conventional activated sludge (CAS) processes. The reclaimed water obtained during the tests demonstrated high-quality in terms of pathogen and metal levels, making it suitable (in Spain) for agricultural, recreational, industrial and environmental uses. However, some legal gaps were identified regarding the use of reclaimed water and microalgae biomass for bio-fertiliser production.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104043"},"PeriodicalIF":4.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Effect of temperature, nitrate concentration, pH and bicarbonate addition on biomass and lipid accumulation in the sporulating green alga PW95.” [Algal. Res. 53: 102148]","authors":"L. Corredor ,&nbsp;E.P. Barnhart ,&nbsp;A.E. Parker ,&nbsp;R. Gerlach ,&nbsp;M.W. Fields","doi":"10.1016/j.algal.2025.104036","DOIUrl":"10.1016/j.algal.2025.104036","url":null,"abstract":"","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"88 ","pages":"Article 104036"},"PeriodicalIF":4.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and activity assay in vivo and in vitro of novel antioxidant and anti-aging peptides from C-phycocyanin of Limnospira platensis","authors":"Chen Zhao ,&nbsp;Fuqiang Li ,&nbsp;Shigan Yan ,&nbsp;Liping Zhu ,&nbsp;Shunan Ma ,&nbsp;Tingxin Zhang ,&nbsp;Nan Zhang ,&nbsp;Haiyan Fang ,&nbsp;Guohui Du","doi":"10.1016/j.algal.2025.104042","DOIUrl":"10.1016/j.algal.2025.104042","url":null,"abstract":"<div><div>C-phycocyanin of <em>Limnospira platensis</em> is a safe and nutritious protein with various activities, including antioxidant and anti-aging, indicating it is a potential protein source for preparation of antioxidant and anti-aging peptides. In this study, C-phycocyanin was purified, enzymatically hydrolyzed by seven commercial proteases, and ultrafiltered to obtain ultra-fractions with molecular weights of &lt;3, 3–10, and &gt;10 kDa. Their antioxidant and anti-aging activities were then evaluated <em>in vitro</em> and <em>in vivo</em>. The results demonstrated that the ultrafraction with a molecular weight of &lt;3 kDa from C-PC hydrolysate by Papain (CPCPH-F3) exhibited high antioxidant and anti-aging activities <em>in vitro</em> and in <em>Caenorhabditis elegans</em>. Subsequently, a batch of peptides was identified from the ultrafractions using UPLC-MS/MS, and their toxicity and activities were predicted through bioinformatics analysis. Among these high antioxidant peptides, three novel antioxidant peptides (FPPWVL, FPPWF, and GW) were selected to be synthesized chemically, and their antioxidation and anti-aging activities were assessed <em>in vitro</em> and in <em>Caenorhabditis elegans</em>. Experimental results showed the three novel peptides exhibited significant antioxidant and anti-aging activities both <em>in vitro</em> and <em>in vivo</em>. These findings are beneficial for the development of bio-peptides and high-value utilization of <em>Limnospira platensis</em>.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104042"},"PeriodicalIF":4.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consequential life cycle assessment of pretreatment strategies for a microalgae-based wastewater treatment pilot unit in a circular livestock industry bioeconomy","authors":"Anaid López-Sánchez ,&nbsp;Carlos Daniel García-López ,&nbsp;Gary Ossmar Lara-Topete ,&nbsp;Juan Daniel Castanier-Rivas ,&nbsp;Paloma Barajas-Álvarez ,&nbsp;Martín Esteban González-López ,&nbsp;Ana Laura Silva-Gálvez ,&nbsp;Hongying Zhou ,&nbsp;Christopher Q. Lan ,&nbsp;Carlos Eduardo Robles-Rodriguez ,&nbsp;Samir Meramo-Hurtado ,&nbsp;Misael Sebastián Gradilla-Hernández","doi":"10.1016/j.algal.2025.104041","DOIUrl":"10.1016/j.algal.2025.104041","url":null,"abstract":"<div><div>This study presents a Consequential Life Cycle Assessment (CLCA) of a microalgae-based wastewater treatment system for the livestock industry, integrated with a circular bioeconomy approach through biofertilizer production and biogas generation through anaerobic digestion (AD). Three treatment scenarios were evaluated, each employing different combinations of pretreatment technologies, including bioflocculation with chitosan. A scaled-up process model was developed using SuperPro Designer, and the environmental performance was assessed using SimaPro 9.7. Results indicate that scenario with a previous pretreatment using a centrifugation and UV radiation achieved the lowest global warming potential (8129 kg CO₂-eq per ton of dried microalgae), reduced fine particulate matter emissions (38.55 kg PM₂.₅-eq), and required less water consumption (114.29 m³) due to minimal chitosan usage compared to the other scenarios. Sensitivity analysis revealed significant variations in environmental impacts based on microalgae yield and biofertilizer application rates. A 20 % increase in biofertilizer application led to a 27.68 % additional reduction in global warming potential. This research provides compelling evidence for the environmental feasibility and economic viability of large-scale microalgae-based wastewater treatment systems, offering a promising pathway towards sustainable livestock practices and a circular bioeconomy within the agricultural sector.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104041"},"PeriodicalIF":4.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonic assisted enzymatic extraction, structural characterization, and tyrosinase inhibition mechanism of phlorotannins from Sargassum horneri","authors":"Yongqi Tian ,&nbsp;Ding Deng ,&nbsp;Haitao Luo ,&nbsp;Mingfeng He ,&nbsp;Shaoyun Wang","doi":"10.1016/j.algal.2025.104038","DOIUrl":"10.1016/j.algal.2025.104038","url":null,"abstract":"<div><div>Phlorotannins, recognized for their efficacy and safety as natural tyrosinase in<em>hibitors, have posed challenges</em> due to their limited extraction efficiency and the elusive nature of their mechanism of action. Here, we developed an ultrasonic-assisted enzymatic extraction (UAEE) protocol that significantly enhanced phlorotannin recovery from Sargassum horneri, achieving a total phenolic content (TPC) of 21.51 mg PGE/g DW. Subsequent purification using solvent extraction and Sephadex LH-20 yielded high-purity alginate phlorotannins (SHP), exhibiting potent DPPH radical scavenging and tyrosinase inhibitory activities, with IC₅₀ values of 22.71 and 26.90 μg/mL, respectively. Structural elucidation based on NMR and MS data suggested that SHP predominantly comprises fucophloroethols, with a degree of polymerization ranging from 3 to 8. Reciprocal plot analysis indicated that SHP inhibits tyrosinase activity through a competitive inhibition mechanism, while fluorescence spectroscopy revealed a dynamic quenching effect of SHP on tyrosinase. Molecular docking studies further elucidated t<em>hat van der Waals forces and</em> hydrophobic interactions are the primary forces governing the interaction between SHP and tyrosinase. Cellular experiments demonstrated the significant inhibitory effects of SHP on both melanin production and tyrosinase activity in B16-F10 cells. This research presents promising lead compounds for the development of novel tyrosinase inhibitors, while also providing theoretical and methodological foundations for the comprehensive utilization of Sargassum horneri.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"88 ","pages":"Article 104038"},"PeriodicalIF":4.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143845155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mild sulfonation process of food grade algae for removal of methyl violet and methylene blue toxic dyes: Statistical modelling and desirability function optimization","authors":"Hasan M. Agha ,&nbsp;Ali H. Jawad ,&nbsp;Lee D. Wilson ,&nbsp;Zeid A. ALOthman","doi":"10.1016/j.algal.2025.104040","DOIUrl":"10.1016/j.algal.2025.104040","url":null,"abstract":"<div><div>In this study, food-grade algae (FGA) underwent a mild sulfonation process via hydrothermal process-assisted activation in 1 M sulfuric acid (H₂SO₄) for 4 h at 100 °C. The sulfonated FGA (S-FGA) was applied to be a potential biosorbent for removal of two structural types of cationic dyes, namely, methyl violet (MV) and methylene blue (MB) from aqueous media. Thus, the physicochemical properties of S-FGA biosorbent were investigated using several analytical methods including XRD, FTIR, SEM-EDX, and pH_pzc. Moreover, the adsorptive performance of S-FGA towards MV and MB dyes was statistically optimized using the Box-Benken design (BBD) with desirability functions. In this process, the key biosorption parameters including S-FGA biosorbent dose (A: 0.02–0.1 g/100 mL), pH of the dye's solution (B: 4–10), and the contact time (C: 10–120 min) were optimized. Thus, the desirability function results indicate the best removal of MV (94.9 %) was achieved using 0.09 g/100 mL of S-FGA dose, pH of 8.2, and contact time of 119 min, while MB removal (74 %) was reached using 0.09 g/100 mL of the S-FGA, pH of 9.5, and 109 min of contact time. The kinetic and isotherm profiles of the biosorption process for MV and MB dyes onto the S-FGA surface followed the pseudo-second order (PSO) kinetic and Freundlich isotherm models, respectively. The estimated biosorption dye capacity (Langmuir model) for MV and MB dyes by S-FGA was 224.6 mg/g and 406.1 mg/g, respectively. The thermodynamic analysis indicates a spontaneous and exothermic-driven biosorption process with decreased randomness at the solid-liquid interface (Δ<em>S°</em> &lt; 0). The biosorption of MV and MB dyes by S-FGA was likely governed by contributions due to hydrogen bonding, Yoshida-H bonding, and electrostatic attractions. Hence, the sulfonation of food algae biomass-based biosorbent shows promising potential for the effective removal of these toxic cationic dyes from contaminated water.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"89 ","pages":"Article 104040"},"PeriodicalIF":4.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}