Masoumeh ZoghAli, Naser Amini, Arash Babaei-Ghazani, Bijan Forogh, Mohammad Taghi Joghataei, Mohammad Reza Babaei, Masih Rikhtehgar, Khatereh Abdolmaleki
{"title":"The Effects of Ultrasound-guided Corticosteroid Injection Compared to Mesenchymal Stem Cell Injection in Patients with Grade II and III Knee Osteoarthritis: A Randomized Double-blind Controlled Trial.","authors":"Masoumeh ZoghAli, Naser Amini, Arash Babaei-Ghazani, Bijan Forogh, Mohammad Taghi Joghataei, Mohammad Reza Babaei, Masih Rikhtehgar, Khatereh Abdolmaleki","doi":"10.1097/PHM.0000000000002691","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002691","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the effects of a single dose injection of mesenchymal stem cells (MSCs) under ultrasound guidance for knee osteoarthritis (KOA).</p><p><strong>Design: </strong>The study included 30 subjects in the intervention group, who received the MSC injection and 27 in the control group who received triamcinolone. Various outcome measures, including pain levels, range of motion (ROM), and MRI parameters, were evaluated before the intervention and at different time points after treatment.</p><p><strong>Result: </strong>The results showed that the MSC group experienced more effective improvements in outcome measures compared to the control group. Pain improvement was significantly different in the MSC group at 2 weeks, 4 weeks, and 24 weeks after the treatment. ROM in extension improved significantly in the MSC group after 4 weeks. Physical function improved significantly in both groups at different time points. Furthermore, the MSC group showed some positive changes in MRI parameters, but it can't be said definitively that they led to an increase in cartilage thickness.</p><p><strong>Conclusion: </strong>In conclusion, the study suggests that a single dose injection of MSCs is safe and holds promise for long-term treatment of KOA. No significant negative effects were reported in either group as a result of the study.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association Between Average Daily Activity Counts and Knee Osteoarthritis Progression.","authors":"Xiaozhen Tang, Dongze Li, Haishan Yao, Xuanchen Chen, Liangquan Fan, Zhenhai Hou","doi":"10.1097/PHM.0000000000002697","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002697","url":null,"abstract":"<p><strong>Objective: </strong>To explore the relationship between daily activity counts and knee osteoarthritis (OA) progression.</p><p><strong>Design: </strong>A cohort study using Osteoarthritis Initiative (OAI) data included 610 participants aged 45-79 years with knee OA or at risk. Daily activity counts were measured using ActiGraph GT1M accelerometers. OA progression was assessed via Kellgren-Lawrence (KL) grade and joint space narrowing (JSN) scores over two years. Cox proportional hazard and Restricted Cubic Spline models identified the dose-response relationship and optimal activity threshold.</p><p><strong>Results: </strong>The average age of participants was 63.7 years, with 44.8% male. A U-shaped relationship was observed between daily activity counts and OA progression. Moderate activity levels could be associated with a reduced risk of KL-grade (adjusted HR: 0.33; 95% CI: 0.24-0.44) and JSN-score progression (HR: 0.31; 95% CI: 0.25-0.38) for activity below 3263.3 counts/min. However, higher activity levels may increase KL-grade (HR: 1.57; 95% CI: 1.40-2.75) and JSN-score progression risk (HR: 1.27; 95% CI: 1.13-1.43).</p><p><strong>Conclusion: </strong>Moderate activity may protect against knee OA progression, while low and high levels may increase risk. Tailored activity recommendations are needed for individuals with or at risk for OA. Future research should investigate the mechanisms and refine activity thresholds for OA management.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hans E Anderson, Alexandra O Polovneff, Matthew J Durand
{"title":"Predicting Discharge Destination from Inpatient Rehabilitation Using Machine Learning.","authors":"Hans E Anderson, Alexandra O Polovneff, Matthew J Durand","doi":"10.1097/PHM.0000000000002680","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002680","url":null,"abstract":"<p><strong>Abstract: </strong>Predicting discharge destination for patients at inpatient rehabilitation facilities is important as it facilitates transitions of care and can improve healthcare resource utilization. This study aims to build on previous studies investigating discharges from inpatient rehabilitation by employing machine learning models to predict discharge disposition to home versus non-home and explore related factors. Fifteen machine learning models were tested. A total of 4922 patient encounters from 4401 patients undergoing inpatient rehabilitation at a Midwestern academic center's inpatient rehabilitation facilities were included. Input variables included demographic and hospital encounter-specific data. The total dataset contained 3687 discharges to home, and 1235 discharges to non-home destinations. A bagging classifier utilizing a decision tree base classifier utilizing random undersampling and without feature selection performed the best in terms of area under the receiver operating characteristic curve with a score of 0.722. Shapley value analysis suggested that length of stay, intravenous medication administration, urinary dysfunction, age, abnormalities white blood cell count or plasma sodium, and fatigue were the factors with the greatest impact on model output. Machine learning can help predict inpatient rehabilitation discharge disposition and identify factors associated with home or non-home discharges.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observational comparison of fatigue and sleep disturbance after traumatic injury, in those with and without concomitant mild traumatic brain injury.","authors":"Jacqueline F I Anderson, Jeong In Park","doi":"10.1097/PHM.0000000000002682","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002682","url":null,"abstract":"<p><strong>Objective: </strong>Fatigue and subjective sleep disturbance are elevated after mild traumatic brain injury (mTBI), raising the question of whether mTBI-specific factors contribute to the experience of fatigue and subjective sleep disturbance after mTBI.</p><p><strong>Design: </strong>110 premorbidly healthy individuals who had suffered a traumatic injury during an accident approximately 8 weeks prior were examined and assessed with subjective measures of fatigue and sleep disturbance, psychological distress and pain.</p><p><strong>Results: </strong>Individuals with a traumatic injury reported significant elevations in most fatigue and all subjective sleep disruption components compared to community-based control participants (n = 45). After controlling for pain, psychological status, sex and premorbid intellectual functioning, those individuals experiencing a mTBI at time of traumatic injury (n = 64) had equivalent levels of fatigue and subjective sleep disruption as those who had experienced no head injury at time of traumatic injury (n = 46). Trauma group membership did not significantly predict fatigue or subjective sleep disturbance. In contrast, psychological distress consistently predicted fatigue and subjective sleep disturbance, with pain also inconsistently predicting some fatigue and subjective sleep disturbance variables.</p><p><strong>Conclusion: </strong>This study suggests it is the experience of suffering traumatic injury, rather than mTBI-specific factors, that is associated with elevations in fatigue and subjective sleep disturbance, approximately 8 weeks after injury.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carl Froilan D Leochico, Angelo S Marasigan, Edmon O Fernandez, Nilo M Arago, Sharon D Ignacio, Jose Alvin P Mojica
{"title":"Telerehabilitation of the shoulder using a low-cost locally developed motion-tracking wearable device from the Philippines: A clinical vignette.","authors":"Carl Froilan D Leochico, Angelo S Marasigan, Edmon O Fernandez, Nilo M Arago, Sharon D Ignacio, Jose Alvin P Mojica","doi":"10.1097/PHM.0000000000002683","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002683","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should we add McKenzie exercises to current guidelines for the treatment of (sub)acute non-specific low back pain? A Cochrane Review summary with commentary.","authors":"Carlotte Kiekens, Stefano Negrini","doi":"10.1097/PHM.0000000000002695","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002695","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dr. Augusta Strongman Alba 1924-2024, Homage to a PM&R.","authors":"John R Bach","doi":"10.1097/PHM.0000000000002696","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002696","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How Effective are Current Interventions to Prevent and Reduce the Use of Physical Restraints for Older People in Long-Term Care Settings? A Cochrane Review Summary with Commentary.","authors":"Sakinah Sabirin, Julia Patrick Engkasan","doi":"10.1097/PHM.0000000000002693","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002693","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Non-Athletic Tear of the Semitendinosus in a Woman: A Visual Vignette.","authors":"Raktim Swarnakar, Menhaj Ahmed, Sohini Datta, Ankit Sarkar","doi":"10.1097/PHM.0000000000002688","DOIUrl":"https://doi.org/10.1097/PHM.0000000000002688","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}