American Journal of Physical Medicine & Rehabilitation最新文献

Women in Rehabilitation Research: What We Need for Progress. 康复研究中的女性：我们需要什么来取得进展。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-08-27 DOI: 10.1097/PHM.0000000000003148

Ahmad J Abdulsalam, Sarah Y Alkandari, Mariam Al-Oraify, Diaa Shehab

引用次数: 0

Bayesian Thinking in Rehabilitation Research. 康复研究中的贝叶斯思维。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-06-29 DOI: 10.1097/PHM.0000000000003080

Farhaan S Vahidy

{"title":"Bayesian Thinking in Rehabilitation Research.","authors":"Farhaan S Vahidy","doi":"10.1097/PHM.0000000000003080","DOIUrl":"10.1097/PHM.0000000000003080","url":null,"abstract":"Objective: To describe key conceptual differences between frequentist and Bayesian statistical approaches and illustrate their relevance to rehabilitation research, where treatment effects are often modest and clinical decision-making occurs under uncertainty.Design: Perspective article comparing inferential frameworks with emphasis on interpretation rather than mathematical formulation. Illustrative examples include neuromodulation studies and a Bayesian reanalysis of the MISTIE III trial.Results: Frequentist methods, centered on P values and confidence intervals, provide established tools for indirect assessment of treatment effects and remain central to trial interpretation, but do not directly estimate the probability that a treatment is beneficial. Bayesian approaches combine prior evidence with observed data to estimate posterior probabilities, including the probability of any benefit or benefit exceeding a clinically meaningful threshold. In illustrative examples, Bayesian interpretation provided a complementary lens for characterizing uncertainty beyond binary significant/nonsignificant conclusions.Conclusion: Bayesian methods complement traditional analyses by providing directly interpretable probabilities of treatment benefit and supporting decision-making under uncertainty. Their conclusions depend on prior assumptions and do not replace rigorous trial design, frequentist inference, or replication.","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"S913-S916"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148343846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond Only Statistical Significance: Understanding and Applying the Minimal Clinically Important Difference in Clinical Research-A Review. 超越统计学意义：理解和应用临床研究中最小的临床重要差异-综述。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-06-22 DOI: 10.1097/PHM.0000000000003068

Seyed Hassan Saneii, Julio Cesar Furlan, Mohammad Alavinia

{"title":"Beyond Only Statistical Significance: Understanding and Applying the Minimal Clinically Important Difference in Clinical Research-A Review.","authors":"Seyed Hassan Saneii, Julio Cesar Furlan, Mohammad Alavinia","doi":"10.1097/PHM.0000000000003068","DOIUrl":"10.1097/PHM.0000000000003068","url":null,"abstract":"Clinically meaningful outcomes require more than statistical significance; they must also represent an actual benefit to patients. The minimum clinically important difference (MCID) is the smallest change in a patient-reported outcome measure (PROM) that is clinically significant to the patient. Despite the growing use of PROMs in clinical research, considerable variability exists in how MCID is defined, calculated, and interpreted across populations and clinical contexts. The objective of this review is to provide a comprehensive summary of the various methods for estimating and interpreting MCID, including distribution-based, anchor-based, and Delphi approaches, and to discuss their relationship with statistical significance in clinical practice. A literature search was conducted using Web of Science, MEDLINE, Embase, PubMed, and Google Scholar. MCID values may vary depending on the patient population, clinical context, and the PROM administered. Each calculation methodology has its strengths and limitations in evaluating clinically meaningful change from baseline to post-treatment. It is recommended to report both a statistically significant difference, defined as P < 0.05, or equivalently a 95% CI that excludes the null value (ie, does not include 0 for mean differences or 1 for odds ratios), and a clinically meaningful difference, defined as an effect size meeting or exceeding the established MCID for the outcome measure. Reporting the effect estimate alongside its 95% CI is encouraged as the primary approach, as this conveys both the magnitude and precision of the finding.","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1080-1088"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148283022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Redefining Spasticity: The Spasticity X Working Group Consensus Statement. 重新定义痉挛：痉挛X工作组共识声明。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-07-02 DOI: 10.1097/PHM.0000000000003082

Gerard E Francisco, Anand Pandyan, Sheng Li, Alberto Esquenazi, Thierry Deltombe, Marjolaine Baude, Alessandro Picelli, Ian Baguley, Stefano Carda, Alessio Baricich, Moon-Suk Bang, Bo Biering-Sørensen, Dirk Dressler, François Genet, Jorge Jacinto, Ryuji Kaji, Patricia Khan, Tiffany Knowlton, Michael C Munin, Preeti Raghavan, Rajiv Reebye, Raymond Rosales, Andrea Santamato, David M Simpson, Areerat Suputtitada, Lynne Turner-Stokes, Jörg Wissel

{"title":"Redefining Spasticity: The Spasticity X Working Group Consensus Statement.","authors":"Gerard E Francisco, Anand Pandyan, Sheng Li, Alberto Esquenazi, Thierry Deltombe, Marjolaine Baude, Alessandro Picelli, Ian Baguley, Stefano Carda, Alessio Baricich, Moon-Suk Bang, Bo Biering-Sørensen, Dirk Dressler, François Genet, Jorge Jacinto, Ryuji Kaji, Patricia Khan, Tiffany Knowlton, Michael C Munin, Preeti Raghavan, Rajiv Reebye, Raymond Rosales, Andrea Santamato, David M Simpson, Areerat Suputtitada, Lynne Turner-Stokes, Jörg Wissel","doi":"10.1097/PHM.0000000000003082","DOIUrl":"10.1097/PHM.0000000000003082","url":null,"abstract":"Inconsistent and variably interpreted definitions of spasticity, alongside evolving mechanistic understanding, highlight the need for a clear, clinically relevant consensus definition. An international expert panel used a modified Delphi process to develop a concise, clinically applicable definition that reflects current understanding and supports consistent assessment and management. Participants reviewed existing definitions, completed a pre‑meeting survey, and engaged in structured discussions, with draft definitions iteratively refined through successive rounds of voting to achieve consensus. Key components identified included disordered sensorimotor control, central nervous system involvement, and velocity‑dependent and length‑dependent resistance to passive stretch, whereas existing definitions were considered either overly narrow or insufficiently relevant to clinical practice. The consensus definition characterizes spasticity as \"A disorder of sensorimotor control resulting from upper motor neuron disease. It is characterized by velocity- and length-dependent involuntary muscle overactivity, which is intermittent or sustained, during passive stretch.\" This definition integrates contemporary mechanistic concepts with clinical applicability and is intended to improve conceptual clarity, facilitate communication, and promote consistency in diagnosis, measurement, and treatment.","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"S926-S931"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148417851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Task-Oriented Training on Health Outcomes in Multiple Sclerosis: A Systematic Review and Meta-Analysis. 任务导向训练对多发性硬化症患者健康结局的影响：一项系统综述和荟萃分析。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-05-05 DOI: 10.1097/PHM.0000000000003028

Alba Navas-Otero, Araceli Ortiz Rubio, Julia Raya-Benítez, Alejandro Heredia-Ciuró, María Granados-Santiago, Laura López-López, Maria Del Carmen Rodríguez-Martínez

{"title":"Impact of Task-Oriented Training on Health Outcomes in Multiple Sclerosis: A Systematic Review and Meta-Analysis.","authors":"Alba Navas-Otero, Araceli Ortiz Rubio, Julia Raya-Benítez, Alejandro Heredia-Ciuró, María Granados-Santiago, Laura López-López, Maria Del Carmen Rodríguez-Martínez","doi":"10.1097/PHM.0000000000003028","DOIUrl":"10.1097/PHM.0000000000003028","url":null,"abstract":"Objective: This systematic review aims to evaluate the impact of TOT on health outcomes in MS individuals.Design: Electronic research was conducted between March and April 2025 among Cochrane, EMBASE, PEDro, SCOPUS PubMed/MEDLINE, REHABDATA, OTseeker, WOS, and Scopus. Studies were systematically selected according to our PICOS strategy: adults with MS, TOT interventions versus no TOT interventions, usual care or no intervention, health outcomes, and randomized controlled trials. This systematic review was previously registered in the PROSPERO database with ID number CRD42025526170. Information about authorship, year of publication, study design, sample size, gender, mean age, MS type, interventions, and outcome measures was extracted from included studies. Methodological quality and risk of bias were also assessed.Results: A total of 385 participants were included. Sessions lasted an average of 55 minutes. The intervention period spanned ~10 weeks and included around 19 sessions. The control groups received treatment of similar duration.Conclusions: TOT shows promise as an effective intervention for improving functional mobility, manual ability, fatigue, walking ability, and walking endurance in MS individuals. However, inconsistencies in training intensity, outcome measures, and study designs highlight the need for standardized protocols and long-term research to determine optimal practices.","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1046-1055"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147939935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does Leucine Supplementation Impact Poststroke Sarcopenia?: A Review of Evidence and Clinical Implications. 补充亮氨酸对中风后肌肉减少症有影响吗？证据和临床意义综述。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-06-19 DOI: 10.1097/PHM.0000000000003074

Mara S Martinez-Santori, Gerard E Francisco

引用次数: 0

Efficacy of Immersive Virtual Reality for Improving Upper Limb Motor Function in Patients With Central Nervous System Disorders: A Systematic Review and Meta-Analysis. 沉浸式虚拟现实改善中枢神经系统疾病患者上肢运动功能的疗效：系统综述和荟萃分析。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-05-08 DOI: 10.1097/PHM.0000000000003032

Natalia Comino-Suárez, Vanesa Herrera, Javier Albusac, Julia Martín-de-Vidales, Ana de Los Reyes

{"title":"Efficacy of Immersive Virtual Reality for Improving Upper Limb Motor Function in Patients With Central Nervous System Disorders: A Systematic Review and Meta-Analysis.","authors":"Natalia Comino-Suárez, Vanesa Herrera, Javier Albusac, Julia Martín-de-Vidales, Ana de Los Reyes","doi":"10.1097/PHM.0000000000003032","DOIUrl":"10.1097/PHM.0000000000003032","url":null,"abstract":"Objectives: To evaluate the effectiveness of immersive virtual reality (VR) on upper extremity (UE) motor function, gross motor dexterity, hand grip strength, and activities of daily living (ADLs) in individuals with central nervous system disorders (CNSDs).Design: A search was conducted in PubMed, PEDro, Cochrane Library, Scopus, and Web of Science. A random-effects meta-analysis with subgroup analyses (comparator, follow-up, intervention type, and number of sessions) was performed.Results: Ten RCTs (n=367) met inclusion criteria. Immersive VR significantly improved UE motor function [SMD=0.56; 95% CI: 0.17-0.95; I2 =67%] compared with conventional or mirror therapy. Gross motor dexterity improved significantly [MD=7.52 blocks/min; 95% CI: 2.22-12.82; I2 =92%]. No significant effect was observed for hand grip strength [MD=1.79 kgf; 95% CI: -13.24, 16.81; I2 =73%]. For ADLs, immersive VR showed a statistically significant benefit [SMD=0.74; 95% CI: 0.44-1.05; I2 =9%].Conclusions: Immersive VR may be a promising intervention for enhancing UE motor function and improving ADLs in individuals with stroke and spinal cord injury. Future research should focus on larger, high-quality clinical trials to optimize intervention protocols and ensure their safety in patients with central nervous system disorders.","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1056-1065"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147969872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preadmission Medication Data Completeness in External Referrals to a Rehabilitation Unit: An Observational Study. 外部转介到康复单位的入院前用药数据完整性：一项观察性研究。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-03-26 DOI: 10.1097/PHM.0000000000002990

Steven Bou, Heide Klumpp, Amanda Kozlowski, Sharon Espinoza

{"title":"Preadmission Medication Data Completeness in External Referrals to a Rehabilitation Unit: An Observational Study.","authors":"Steven Bou, Heide Klumpp, Amanda Kozlowski, Sharon Espinoza","doi":"10.1097/PHM.0000000000002990","DOIUrl":"10.1097/PHM.0000000000002990","url":null,"abstract":"Objective: Medical records are used to facilitate preadmission screening in external referrals to inpatient rehabilitation facilities (IRFs). This study aimed to assess structured medication data completeness in documentation received in these referrals.Design: Eligible medical records faxed from referring hospitals (due to lack of interoperability) to a Veterans Affairs (VA) hospital for potential rehabilitation unit admission were examined for structured medication data completeness. Medication data elements and formats (eg, standalone reports with and without lookback periods and lists in progress notes) were evaluated. Subgroup analyses were performed for high-risk medications and data from the most frequently referring hospital. χ 2 analysis was used to evaluate associations between data format and completeness.Results: Of 105 referrals, 103 contained structured medication data. All data formats had gaps in medication data completeness. Standalone reports with lookback periods had the highest degree of completeness. χ 2 results demonstrated significant associations between data format and completeness across all elements assessed. Subgroup analyses for high-risk medications and data from the most frequently referring hospital showed similar findings, except for nonsignificant associations between data format and dose element completeness.Conclusions: Standalone reports with lookback periods have greater medication data completeness compared with other formats used for conveying medication data.","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1006-1013"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147643525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Letter to Editor on "Ultrasound-guided Aspiration of Baker's Cyst Combined With Intracystic Platelet-rich Plasma Injection in Knee Osteoarthritis: A Randomized Controlled Trial". 关于“超声引导下贝克囊肿穿刺联合囊内富血小板血浆注射治疗膝骨关节炎：一项随机对照试验”的回复。

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-08-21 DOI: 10.1097/PHM.0000000000003141

Oğuz Akarsu, Ayhan Aşkın, Korhan Barış Bayram, Dilek Mert, İlker Şengül

引用次数: 0

Causal Claims Linking Sleep Duration With Sarcopenia-Related Phenotypes. 睡眠时间与肌少症相关表型的因果关系

IF 2.3 4区医学

American Journal of Physical Medicine & Rehabilitation Pub Date : 2026-11-01 Epub Date: 2026-07-10 DOI: 10.1097/PHM.0000000000003093

Zongyuan Tang, Xu Hu, Siwang Zhao, Jun Tao

引用次数: 0