{"title":"Platelet-rich Plasma for Baker's Cysts: Methodological and Mechanistic Considerations.","authors":"Timur Ekiz","doi":"10.1097/PHM.0000000000003142","DOIUrl":"10.1097/PHM.0000000000003142","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"e153-e154"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148808089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predicting Complete Injury in Spinal Cord Injury Patients by Applying Machine Learning Methods to Heart Rate Variability.","authors":"Azharmadani Syed, Bowen Yang, Argyrios Stampas, Tianfu Wu","doi":"10.1097/PHM.0000000000002991","DOIUrl":"10.1097/PHM.0000000000002991","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to develop a model using machine learning algorithms for diagnosing complete and incomplete injury from heart rate variation (HRV) parameters and other easily obtained demographics.</p><p><strong>Methods: </strong>Random Forest, Decision Tree, KNN Classifier, Gradient Boost, Bagging Classifier, Support Vector Machine, Voting Classifier, XGB Classifier, MLP Classifier and feedforward neural networks were trained on 296 sets of patient data, including 11 HRV parameters. Feature selection methods were used to improve models and identify parameters with high contribution to model predictions.</p><p><strong>Results: </strong>The feature selected MLP Classifier achieved an accuracy of 85.33%, with an AUC of 0.8590, while the neural network model had an accuracy of 86.67% with an AUC of 0.9608. Location of spinal injury, age, mean heart rate and mean R-R interval were the greatest contributors to the machine learning models.</p><p><strong>Conclusions: </strong>This study demonstrated that machine learning algorithms trained on HRV data could be an invaluable tool for diagnosing and monitoring people with SCI and overall improving their quality of life.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1014-1021"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147669875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brainstem Symptoms With Unexpected Motor Deficits: A Clinical Vignette.","authors":"Vyvan Nguyen, Eric Altschuler, Neil Jasey","doi":"10.1097/PHM.0000000000003000","DOIUrl":"10.1097/PHM.0000000000003000","url":null,"abstract":"<p><p>Clinical Vignettes published in the Resident Fellow Section (RFS) do not require abstracts. Attached is the link that this guidance was obtained from: https://journals.lww.com/ajpmr/Pages/informationforauthors.aspx.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"e166-e168"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147969830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prakash Jayabalan, Yelyzaveta Merenzon, Audrey Lazar, Sanchita Sen, Vikram Darbhe, Elizabeth Gray, Thomas Schnitzer, Leah Welty
{"title":"Lower Positive Body Pressure Walking Significantly Improves Pain and Function In Individuals With Knee Osteoarthritis: A Pilot Randomized Clinical Trial.","authors":"Prakash Jayabalan, Yelyzaveta Merenzon, Audrey Lazar, Sanchita Sen, Vikram Darbhe, Elizabeth Gray, Thomas Schnitzer, Leah Welty","doi":"10.1097/PHM.0000000000003007","DOIUrl":"10.1097/PHM.0000000000003007","url":null,"abstract":"<p><strong>Objectives: </strong>Body weight-supported (BWS) walking therapies, lower-body positive pressure (LBPP) treadmills, or aquatic pool walking could provide a treatment to reduce pain in individuals with knee osteoarthritis (OA). Our objective was to examine the potential benefits of BWS for individuals with knee OA.</p><p><strong>Design: </strong>Parallel group randomized clinical trial. Forty-nine (n=49) participants, aged above 50 with knee OA, were randomly assigned to 1 of 3 groups: (1) control (n=16), (2) aquatic (n=17), and (3) LBPP (n=16). Interventional groups had two 30-minute walking sessions for 8 weeks. The control group received no active treatment. The primary outcome was the change in Knee Injury and Osteoarthritis Outcome Score (KOOS)-Pain from baseline to 8 weeks. Secondary outcomes included other KOOS subscales, 6-minute walk test (6-MWT), joint kinematics, and serum cytokine concentration.</p><p><strong>Results: </strong>Forty-one participants completed the trial. Changes in KOOS-Pain from baseline to 8 weeks were statistically significant and clinically relevant in the LBPP group (15.3, 95% CI: 5.0, 25.6). Changes in the other groups were not statistically significant [aquatic 0.9 (95% CI: -7.8, 9.6); and control -3.3 (95% CI: -12.3, 5.7). Post hoc analyses indicated improvements were significantly larger with LBPP. This group improved in 6-MWT (58.9 m, 95% CI: 26.1, 91.7) and most KOOS subscales. Improvements in KOOS-Pain at 8 weeks in the LBPP group were associated with increased knee flexion ( P =0.02). Only the control group had significant increases in IL-1β ( P =0.04) and IL-1RA ( P =0.02) concentration at 8 weeks.</p><p><strong>Conclusions: </strong>This is the first randomized controlled trial of BWS for knee OA and showed the benefits of LBPP treadmill walking. Future, larger studies should assess the effect size, sustained benefits, and cost-effectiveness.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1030-1038"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hao Meng, Michael Houston, Ahmad Z Rao, Jinsook Rho, Gerard E Francisco, Sheng Li
{"title":"Effects of Single-Session High-Definition Transcranial Alternating Current Stimulation (HD-tACS) Combined with Robot-Assisted Hand Exercises on Corticospinal Excitability in Chronic Stroke.","authors":"Hao Meng, Michael Houston, Ahmad Z Rao, Jinsook Rho, Gerard E Francisco, Sheng Li","doi":"10.1097/PHM.0000000000003108","DOIUrl":"10.1097/PHM.0000000000003108","url":null,"abstract":"<p><strong>Objective: </strong>This preliminary study investigated whether a single session of high-definition transcranial alternating current stimulation (HD-tACS) could improve corticospinal tract (CST) excitability compared with sham stimulation in healthy individuals and individuals with chronic stroke.</p><p><strong>Design: </strong>Twelve healthy adults and 7 individuals with chronic stroke received active and sham HD-tACS over the primary motor cortex (M1) flexor digitorum superficialis (FDS) hotspot, ipsilesional in stroke subjects, for 30 minutes at 2mA and 21 Hz in a randomized crossover design. All subjects performed robot-assisted grasp-and-open hand exercises during active and sham stimulation.</p><p><strong>Results: </strong>HD-tACS significantly increased FDS MEP amplitudes in the healthy group (15.3%). In the stroke group, FDS MEP amplitudes were increased by ∼22.3% after HD-tACS, but this change was not statistically significant. When MEP amplitudes were normalized as percentage change, HD-tACS significantly increased FDS MEP amplitudes in both groups compared with the sham condition. No significant extensor digitorum communis (EDC) modulation was observed in either group.</p><p><strong>Conclusion: </strong>HD-tACS combined with robot-assisted hand exercises may enhance CST excitability compared with robot-assisted hand exercises alone after a single session in both healthy and stroke subjects. However, larger studies are needed to confirm these findings.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":"105 11S Suppl 4","pages":"S906-S912"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriela Ruiz-Castro, Roger De la Cerna-Luna, Midori Chacon-Cruzado, Paula Arnillas Brigneti, Rajiv N Reebye
{"title":"A Novel Spasticity Education Without Borders Platform: Impact of the Spasticity Education and Clinical Translation (SPECTRA) Summer School International Curriculum.","authors":"Gabriela Ruiz-Castro, Roger De la Cerna-Luna, Midori Chacon-Cruzado, Paula Arnillas Brigneti, Rajiv N Reebye","doi":"10.1097/PHM.0000000000003145","DOIUrl":"10.1097/PHM.0000000000003145","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"e154-e156"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148824012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Momentum Lab: The Interim Spasticity X Symposium.","authors":"","doi":"10.1097/PHM.0000000000003162","DOIUrl":"https://doi.org/10.1097/PHM.0000000000003162","url":null,"abstract":"","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":"105 11S Suppl 4","pages":"S937-S945"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter D Vu, Radha Korupolu, Cindy B Ivanhoe, Sheng Li, Gerard E Francisco
{"title":"Factors Influencing the Selection of Botulinum Toxin Preparations for the Management of Spasticity.","authors":"Peter D Vu, Radha Korupolu, Cindy B Ivanhoe, Sheng Li, Gerard E Francisco","doi":"10.1097/PHM.0000000000002861","DOIUrl":"10.1097/PHM.0000000000002861","url":null,"abstract":"<p><strong>Objective: </strong>To identify and prioritize key factors influencing clinicians' selection of BoNT formulations for chronic spasticity treatment to inform future guidelines and standardize decision-making.</p><p><strong>Design: </strong>Modified two-round Delphi study with international spasticity management experts.</p><p><strong>Setting: </strong>International survey involving clinicians from various practice settings.</p><p><strong>Participants: </strong>Round 1: 108 clinicians rating decision factors; Round 2: 55 respondents ranking factors. Convenience sampling of international spasticity experts.</p><p><strong>Main outcome measures: </strong>Importance ratings of seven decision-making categories using 5-point Likert scales (Round 1) and factor ranking (Round 2). Inter-rater agreement assessed using Kendall's coefficient of concordance.</p><p><strong>Results: </strong>Respondents primarily used onabotulinumtoxinA, abobotulinumtoxinA, and incobotulinumtoxinA. Round 1 identified economic factors as most important (mean 3.74 points), followed by hospital/system factors (3.53 points) and toxin-specific factors (3.27 points). Round 2 revealed disease-specific factors as highest priority (14 first-place votes, mean rank 3.42 points), followed by injector expertise and toxin characteristics. Kendall's coefficient was 0.35, indicating moderate agreement.</p><p><strong>Conclusions: </strong>BoNT formulation selection involves multiple factors with significant practice variability. While economic and institutional considerations influence decisions, clinicians prioritize disease characteristics, clinical expertise, and toxin properties when ranking options. Evidence-based guidelines are needed to reduce practice variation and improve BoNT-based spasticity management.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"S897-S903"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148270010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karen P Barr, Kalie Webb, Haylie Kromer Lecker, Paige Matijasich, Matthew Mesoros, Kerry DeLuca
{"title":"An Initiative to Assess Frailty and Functional Status in Cardiac Transplant Candidates.","authors":"Karen P Barr, Kalie Webb, Haylie Kromer Lecker, Paige Matijasich, Matthew Mesoros, Kerry DeLuca","doi":"10.1097/PHM.0000000000003015","DOIUrl":"10.1097/PHM.0000000000003015","url":null,"abstract":"<p><p>The systematic evaluation of frailty is recommended as best practice in heart transplantation, but can be challenging to implement. This initiative assesses the implementation of frailty assessment for heart transplant candidates in the inpatient setting and describes frailty characteristics and content of prehabilitation plans in this population. All patients assessed for heart transplantation while hospitalized at our institution between October 30, 2023 and January 6, 2025, in whom PM&R was consulted, were reviewed. Objective frailty measures, their correlation to listing for transplantation, and the content of prehabilitation plans were assessed. All 56 inpatient consults included completed frailty assessments performed by a multidisciplinary team and interpreted by a PM&R physician. About 32% had mFFP scores in the frail range, and 25% had SPPBs in the frail range. No patients with SPPB in the frail range were listed for transplantation during the review period. All patients received prehabilitation plans with multiple recommendations in the areas of therapy/exercise, nutrition, and enhancing resilience. We conclude it is feasible to implement a sustainable, coordinated multidisciplinary frailty evaluation for hospitalized patients undergoing assessment for heart transplantation under PM&R physician leadership to inform the selection committee for risk stratification and created prehabilitation plans designed to improve patients' functional status.</p>","PeriodicalId":7850,"journal":{"name":"American Journal of Physical Medicine & Rehabilitation","volume":" ","pages":"1089-1093"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147939829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}