Anesthesiology and Pain Medicine最新文献

{"title":"Effectiveness of Pulse Intravenous Infusion of Methylprednisolone on Pain in Patients with Lumbar Disc Herniation: A Randomized Controlled Trial.","authors":"Hassan Reza Mohammadi, Yousef Asadoola, Ali Erfani, Nazila Ghoreishi Amin, Hosein Karimiyarandi, Sohrab Sadeghi, Mohammad Abiri","doi":"10.5812/aapm-149442","DOIUrl":"10.5812/aapm-149442","url":null,"abstract":"<p><strong>Background: </strong>Lumbar disc herniation (LDH) can cause pain in the lower back and leg, as well as numbness or weakness in the affected area. Various steroids, including methylprednisolone, are currently used for treatment.</p><p><strong>Objectives: </strong>This study aimed to compare the effectiveness of pulse intravenous infusion of 500 mg methylprednisolone with common non-steroidal anti-inflammatory drugs (NSAIDs) in relieving pain and improving the clinical condition of patients with lumbar disc herniation.</p><p><strong>Methods: </strong>This clinical trial, registered under code IRCT20211116053077N1, included an experimental group (37 patients) and a control group (35 patients). Pain assessments were conducted before treatment, and at one, two, and three weeks, as well as one and six months after treatment. The control group received common painkillers (diclofenac sodium tablets 100 mg), while the experimental group received a single dose of 500 mg methylprednisolone sodium succinate (intravenous injection in 500 cc normal saline). Pain scores were analyzed using SPSS 16 and statistical tests such as ANOVA, independent <i>t</i>-tests, and repeated measures ANOVA.</p><p><strong>Results: </strong>Prior to intervention, the mean (SD) pain score was 8.7 (3.57) in the experimental group and 8.17 (0.66) in the control group (P > 0.76). Six months after methylprednisolone injection, the mean (SD) pain score in the experimental group was 1.56 (0.83), compared to 6.48 (0.91) in the control group (P = 0.000). Analysis of variance indicated that methylprednisolone significantly reduced pain in patients with LDH (P = 0.000, F = 660.668).</p><p><strong>Conclusions: </strong>Given the effectiveness of intravenous pulse infusion of 500 mg methylprednisolone compared to common NSAIDs in relieving pain and improving clinical outcomes for patients with lumbar disc herniation, the use of this drug is recommended for pain reduction in these patients.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 4","pages":"e149442"},"PeriodicalIF":0.0,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Efficacy of Electroacupuncture Compared to Physiotherapy in Reducing Pain and Disability in Soldiers Diagnosed with Chondromalacia Patella: A Randomized Clinical Trial.","authors":"Reza Kazempour Mofrad, Afsaneh Dadarkhah, Zahra Rezasoltani, Sharif Najafi","doi":"10.5812/aapm-143688","DOIUrl":"10.5812/aapm-143688","url":null,"abstract":"<p><strong>Background: </strong>One of the most prevalent causes of anterior knee pain is chondromalacia patella (CMP), particularly among young populations, including soldiers. Although various treatments have been suggested to relieve the symptoms and improve the functioning of patients with CMP, none have proven to be adequately effective.</p><p><strong>Objectives: </strong>This study assessed the effectiveness of electroacupuncture as a complementary treatment for CMP, noting its minimal complications.</p><p><strong>Methods: </strong>In this randomized clinical trial, soldiers diagnosed with CMP who met the inclusion criteria and referred to Imam Reza Hospital in Tehran in 2023 were assigned to one of two treatment groups. The electroacupuncture group received treatment at specific acupuncture points combined with an electrical current. The physical therapy group underwent treatment consisting of 10 sessions of routine physical therapy modalities. The Visual Analog Scale (VAS) for pain and disability and the knee injury and osteoarthritis outcome score (KOOS) questionnaire were used to assess the outcomes before the intervention and three months after the intervention.</p><p><strong>Results: </strong>Twenty participants were analyzed in each group. The VAS for pain and disability reduced in both groups during the study; however, the difference between the two groups was not significant (P = 0.999 for pain and P = 0.873 for disability). No significant difference was observed in the KOOS symptom score either during the study or between the two groups (P = 0.423). The changes in the \"pain\" scores of the KOOS questionnaire were significant both in the electroacupuncture group (P = 0.003) and in the physical therapy group (P = 0.038); however, the difference was not significant between the two groups. The \"activities of daily living\" scores of the patients were significant both during the study and between the two groups (P = 0.042), with a steeper improvement in the electroacupuncture group. The patients' \"sports and recreational activities\" scores were significant in the electroacupuncture group (P = 0.001) and between the two groups (P = 0.023). The \"knee-related quality-of-life\" scores were significant in both groups, and the comparison of the two groups indicated that the slope of the changes was higher in the electroacupuncture group than in the physical therapy group (P = 0.001).</p><p><strong>Conclusions: </strong>According to the results of the current research, electroacupuncture can improve the symptoms and function of patients with CMP, and its efficacy is equivalent to that of physical therapy.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 4","pages":"e143688"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcutaneous Pulsed Radiofrequency Treatment in Patients with Osteoarthritis of the Upper Extremity.","authors":"Pleun Janssens, Iris Koenraadt-van Oost, Leonieke van Boekel, Denise Eygendaal, Annechien Beumer, Miriam van der Velden, Bertram The","doi":"10.5812/aapm-146816","DOIUrl":"10.5812/aapm-146816","url":null,"abstract":"<p><strong>Background: </strong>Non-invasive treatment options are preferred for managing upper extremity pain due to osteoarthritis (OA). Transcutaneous pulsed radiofrequency (TcPRF) is a promising technique and appears effective in managing knee and shoulder pain.</p><p><strong>Objectives: </strong>To investigate whether TcPRF treatment is effective in reducing pain and safe to use among patients with OA of the upper extremity.</p><p><strong>Methods: </strong>In this retrospective study, patients with painful OA of the upper extremity who underwent TcPRF treatment from February 2021 to February 2022 were included. The primary outcome measure was the change in NRS pain scores between baseline and 1, 2, and 6 weeks of follow-up. Secondary outcome measures included adverse events. Data were extracted from electronic medical records and via telephone consultation after the 6-week follow-up.</p><p><strong>Results: </strong>A total of 41 initial TcPRF treatments were performed among 37 patients. The NRS score at rest showed a statistically significant improvement at 6 weeks [median = 5 [interquartile range (IQR) 2 - 8)] compared with baseline [median = 6 (IQR 4 - 8)], P = 0.023, with a moderate effect size, r = -0.44. For NRS scores during activity, all follow-up moments had lower NRS scores [median = 7 (IQR 5 - 8)] than before TcPRF [median = 8 (IQR 7 - 9)], P = 0.002 - 0.006, with moderate to large effect sizes, r = -0.45 to r = -0.51. No adverse events were reported.</p><p><strong>Conclusions: </strong>Transcutaneous pulsed radiofrequency treatment is effective in reducing pain and is safe to use among patients with upper extremity pain due to OA.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 4","pages":"e146816"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Power of Color Flow Doppler Ultrasonography Versus Blind Technique in Localization of Epidural Catheter: A Randomized Prospective Study.","authors":"Atef Mohamed Mahmoud, Safaa Gaber Ragab, Taha Mohamed Agamy, Abeer Shaban Goda","doi":"10.5812/aapm-147828","DOIUrl":"https://doi.org/10.5812/aapm-147828","url":null,"abstract":"<p><strong>Background: </strong>The success of epidural analgesia hinges on the precise insertion of the needle within the epidural space; failure rates have been reported to reach 32%.</p><p><strong>Objectives: </strong>We report a new method using color Doppler to help verify the accurate location of the epidural needle tip.</p><p><strong>Methods: </strong>This is a randomized prospective study. Sixty patients undergoing hysterectomy were enrolled, with 30 patients in each group. Color flow Doppler (CFD) ultrasonography was employed to guide epidural catheter placement. The ultrasound-guided epidural technique was used for patients where challenges in identifying traditional landmarks for epidural space localization were anticipated. The procedure commenced with a spinal epidural technique. After sterile preparation and draping of the area, a curvilinear ultrasound transducer, encased in a sterile sheath, was used to locate the interspinous space. The primary outcome measure focused on flow visualization at different insertion levels. Secondary outcome measures included the duration of catheter implantation, intervertebral level of insertion, and dermatome sensory levels. The study also assessed the quality of epidural analgesia and patients' assessment of analgesic quality using a Verbal Numerical Rating Scale.</p><p><strong>Results: </strong>The study reported a successful and predominantly safe outcome, with high success rates in flow visualization and effective anesthesia coverage. Flow visualization at the insertion and surrounding levels demonstrated a 100% success rate at all observed points. The Visual Numeric Rating Scale (VNRS) results indicated a median pain score of 2 with an interquartile range (IQR) of 2 - 3, showcasing a generally low level of post-procedural pain among the subjects, reflecting good quality post-operative analgesia. Regarding dermatome sensory levels after 2 hours, the distribution across various levels, including T4, T6, T7, T8, T10, and T12, exhibited a favorable outcome. The highest proportion was observed at T10 (68.3%), suggesting effective anesthesia coverage in the targeted areas. The study demonstrated comparable efficiency between the CFD-guided and blind techniques in terms of procedural aspects. However, notable distinctions were observed in patients' reported pain levels, with the CFD group experiencing lower pain compared to the blind technique group. Additionally, the study highlighted the association between CFD and improved procedural accuracy and safety.</p><p><strong>Conclusions: </strong>This study advocates for the integration of CFD into routine clinical practice to enhance procedural outcomes and patient safety during hysterectomy surgeries.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 3","pages":"e147828"},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11480820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal Anesthesia Management in a 30-Year-Old Patient with Progeria Syndrome: A Case Report.","authors":"Maryam Vosoughian, Faramarz Mosaffa, Shide Dabir, Mastaneh Dahi Taleghani","doi":"10.5812/aapm-147344","DOIUrl":"https://doi.org/10.5812/aapm-147344","url":null,"abstract":"<p><p>Progeria syndrome is a rare genetic disorder resulting in premature aging. General anesthesia is very challenging in these patients due to difficult intubation and age-related comorbidities. We describe spinal anesthesia management in a 30-year-old man with progeria syndrome. To our knowledge, this is the first report on using spinal anesthesia in this group of patients.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 3","pages":"e147344"},"PeriodicalIF":0.0,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11480815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic Pediatric Urologic Surgery-Clinical Anesthetic Considerations: A Comprehensive Review.","authors":"Nazih Khater, Seth Swinney, Joseph Fitz-Gerald, Ahmad S Abdelrazek, Natalie M Domingue, Sahar Shekoohi, Farnad Imani, Tahereh Chavoshi, Ali Moshki, Kimberly L Skidmore, Alan D Kaye","doi":"10.5812/aapm-146438","DOIUrl":"https://doi.org/10.5812/aapm-146438","url":null,"abstract":"<p><p>Minimally invasive robotic approaches have become standard in many institutions over the last decade for various pediatric urological procedures. The anesthetic considerations for common laparoscopic and robotic-assisted surgeries are similar since both require the insufflation of CO₂ to adequately visualize the operative area. However, few studies exist regarding anesthesia for robotic procedures in children. We hypothesized that pediatric patients undergoing robotic urologic surgeries would require specific anesthetic strategies, especially given the inherently longer durations of these procedures. This study aimed to evaluate anesthetic considerations, current robotic procedures, optimal patient positioning, and port placement for robotic-assisted surgery in pediatric patients. A comprehensive literature review of all published manuscripts from PubMed, EMBASE database, and Google Scholar was performed, focusing on robotic procedures involving pediatric patients, anesthesia for pediatric urology patients, and related topics from 1996 to 2023. Forty published manuscripts were identified and reviewed in depth. In pediatric cases, insufflation pressures and volumes are lower due to the laxity of the abdominal wall. However, the increase in intra-abdominal pressure and absorption of CO₂ may result in disproportionate changes in cardiopulmonary function. Specific patient positioning for robotic approaches may further compound these physiological changes. Correct patient positioning is essential to facilitate surgery optimally and safely. Understanding the physiological changes that can occur during a pediatric patient's robotic urologic surgery allows for safer anesthesia management.</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 3","pages":"e146438"},"PeriodicalIF":0.0,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11473995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthetic Management Recommendations Using a Machine Learning Algorithm to Reduce the Risk of Acute Kidney Injury After Cardiac Surgeries","authors":"A. A. Abin, Ahmad Molla, Azar Ejmalian, Shahabedin Nabavi, Behnaz Memari, Kamal Fani, Ali Dabbagh","doi":"10.5812/aapm-143853","DOIUrl":"https://doi.org/10.5812/aapm-143853","url":null,"abstract":"Background: Open heart surgeries are a common surgical approach among patients with heart disease. Acute kidney injury (AKI) is one of the most common postoperative complications following cardiac surgeries, with an average incidence of 6 - 10%. Additionally, AKI has a mortality rate of 5 - 10%. One of the challenges of cardiac surgeries is selecting the appropriate anesthetic approaches to reduce the risk of AKI. Objectives: This study presents a machine learning-based method that consists of two regression models. These models can inform the anesthesiologist about the risk of AKI resulting from the improper selection of anesthetic parameters. Methods: In this cohort study, the medical records of 998 patients who underwent cardiac surgery were collected. The proposed method includes two regression models. The first regression model recommends optimal anesthesia parameters to minimize the risk of AKI. The second model provides the anesthesiologist with the safest margin for deciding on anesthetic parameters during surgery, including cardiopulmonary bypass (CPB) time, anesthesia time, crystalloid dose, diuretic dose, and transfusion of packed red cells (PC) and fresh frozen plasma (FFP). Using this method, the specialist can evaluate the anesthetic parameters and assess the potential AKI risk. Additionally, the proposed method can also provide the treatment team with anesthetic parameters that carry the lowest risk of AKI. Results: This method was evaluated using data from 526 patients who suffered from postoperative AKI (AKI+) and 472 who did not suffer any injury (AKI-). The accuracy of the proposed method is 80.6%. Additionally, the evaluation of the proposed method by three experienced cardiac anesthesiologists shows a high correlation between the results of the proposed method and the opinions of the anesthesiologists. Conclusions: The results indicated that the outputs of the proposed models and the designed software could help reduce the risk of postoperative AKI.","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"21 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141383685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Note: The Effect of Dexmedetomidine and Esmolol on Early Postoperative Cognitive Dysfunction After Middle Ear Surgery Under Hypotensive Technique: A Comparative, Randomized, Double-blind Study.","authors":"Mahmood-Reza Alebouyeh","doi":"10.5812/aapm.149456","DOIUrl":"https://doi.org/10.5812/aapm.149456","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.5812/aapm.107659.].</p>","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"14 3","pages":"e149456"},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11480816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Narrative Review on Pain Management in Head and Neck Cancer: Integrating Multimodal Analgesia and Interventional Procedures","authors":"F. Imani, Saleh Mohebbi, Masoud Mohseni, Behnaz Karimi, Saeid Rahimi, Gholamali Dikafraz Shokooh","doi":"10.5812/aapm-146825","DOIUrl":"https://doi.org/10.5812/aapm-146825","url":null,"abstract":": Surgical interventions and radiotherapy for head and neck cancer frequently result in substantial instances of acute and chronic discomfort. Optimizing pain management techniques stands as a pivotal factor in enhancing the well-being and overall quality of life for patients. This comprehensive review discusses various pain conditions encountered after head and neck cancer and explores a multidimensional approach to pain management. The review highlights the significance of incorporating multimodal analgesia, physical therapy, psychological support, palliative care, and emerging techniques including nerve blocks to achieve efficacious pain control. Such an endeavor necessitates cooperation among head and neck surgeons, radiotherapists, and pain specialists.","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141279080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexmedetomidine Versus Fentanyl on Time to Extubation in Patients with Morbid Obesity Undergoing Laparoscopic Sleeve Gastrectomy","authors":"Doha Mohammed Bakr, Rasha Behery Youssef, Maged Salah Mohamed, M. S. Khalil","doi":"10.5812/aapm-144776","DOIUrl":"https://doi.org/10.5812/aapm-144776","url":null,"abstract":"Background: Sleeve gastrectomy (SG) is an effective method for managing obesity. While opioids are used for their hemodynamic stability and their ability to reduce intraoperative stress, they also have reported side effects. Dexmedetomidine (DEX), an α2 adrenergic receptor agonist, is noted for its analgesic and anesthetic-sparing effects, leading to a higher quality of recovery. Objectives: The study aims to compare the effects of fentanyl and dexmedetomidine (DEX) on the recovery of morbidly obese patients following laparoscopic sleeve gastrectomy (SG). Methods: This randomized, double-blind study involved 64 patients, equally divided into two groups. The Dexmedetomidine group (Group D) received an intravenous (IV) loading dose of dexmedetomidine (1 μg/kg) over 15 minutes before anesthesia induction, followed by a 10 ml saline 0.9% infusion over 60 seconds during induction. Post-intubation, dexmedetomidine was administered at 0.5 μg/kg/h. The Fentanyl group (Group F) received a volume-matched saline 0.9% IV over 15 minutes pre-induction and fentanyl (1 μg/kg) diluted in 10 ml saline 0.9% IV over 60 seconds during induction. After intubation, a continuous fentanyl infusion was maintained at a rate of 1 μg/kg/hr. Results: Extubation time was significantly shorter in the Dexmedetomidine group (Group D) at 8.25 ± 2.7 minutes compared to the Fentanyl group (Group F) at 10.47 ± 2.17 minutes, with a P value of 0.001. Intraoperative heart rate and mean arterial blood pressure were also significantly lower in Group D than in Group F. Visual analogue scale (VAS) pain scores were significantly lower in Group D compared to Group F upon arrival at the post-anesthesia care unit and at 2 hours postoperatively (P-value < 0.05). Additionally, the morphine dose consumed in the first 12 hours after surgery was significantly lower in Group D (5.75 ± 2.20 mg) compared to Group F (8 ± 2.38 mg), with a P-value of 0.001. Conclusions: For morbidly obese patients undergoing laparoscopic sleeve gastrectomy, dexmedetomidine (DEX) proves to be an effective anesthetic choice. It not only reduces extubation time but also lowers early postoperative visual analogue scale (VAS) pain scores and opioid consumption within the first 12 hours following surgery.","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"45 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140975738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}