CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130155
S Henry, M M Cohen, D T Karzon
{"title":"Cytogenetic effects of measles virus fusion factor (FF) on human leukocytes.","authors":"S Henry, M M Cohen, D T Karzon","doi":"10.1159/000130155","DOIUrl":"https://doi.org/10.1159/000130155","url":null,"abstract":"In human leukocyte cultures, extensive chromosome changes (pulverization, uncoiling, or a combination of these) induced by UV-inactivated measles virus (fusion factor or FF) (1) wer","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 5","pages":"367-76"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130155","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16242951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130136
D H Wurster, J R Snapper, K Benirschke
{"title":"Unusually large sex chromosomes: new methods of measuring and description of karyotypes of six rodents (Myomorpha and Hystricomorpha) and one lagomorph (Ochontonidae).","authors":"D H Wurster, J R Snapper, K Benirschke","doi":"10.1159/000130136","DOIUrl":"https://doi.org/10.1159/000130136","url":null,"abstract":"Chromosome studies of six rodents, of which three have unusually large X chromosomes, and one lagomorph have been made. Two new methods of measuring unusually large sex chromosomes are presented. Comp","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 3","pages":"153-76"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130136","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16242988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130143
R M Kitchin, M W Shaw
{"title":"The association pattern of the Ph chromosome.","authors":"R M Kitchin, M W Shaw","doi":"10.1159/000130143","DOIUrl":"https://doi.org/10.1159/000130143","url":null,"abstract":"A total of 951 Ph1+ cells and 364 Ph1–cells from a female patient with chronic myelogenous leukemia was scored for acrocentric associations. The Ph1+ and Ph1-cells differed significantly in their association patterns. The average number of association groups per cell, the average size of the groups, and the total number of chromosomes involved in associations per cell were significantly lower in the Ph1+ cells. Although the Ph1 chromosome itself tended to be found in association more often than expected by chance, it appeared to associate at random with the other acrocentrics.","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 4","pages":"235-43"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130143","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16375273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130131
W. Engel, W. Vogel, H. Reinwein
{"title":"[Autoradiographic studies on X-autosomal translocation in man: 45,X.15-,tan(15qZq+)+].","authors":"W. Engel, W. Vogel, H. Reinwein","doi":"10.1159/000130131","DOIUrl":"https://doi.org/10.1159/000130131","url":null,"abstract":"In a female infant exhibiting cleft palate, hydrocephalus communicans, vitium cordis congenitum, and other anomalies, chromosome analysis revealed a C/D translocation. According to its replication pat","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 2 1","pages":"87-98"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64617019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130127
B Padeh, M Wyskoki, M Soller
{"title":"Further studies on a Robertsonian translocation in the Saanen dairy goat.","authors":"B Padeh, M Wyskoki, M Soller","doi":"10.1159/000130127","DOIUrl":"https://doi.org/10.1159/000130127","url":null,"abstract":"Additional observations on a Robertsonian translocation segregating in the Saanen goat are reported. All of the animals born in this series of matings had balanced karyotypes, and all were phenotypica","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 1","pages":"61-9"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130127","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16196558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sex-chromosome mosaicism in pouch young of marsupials Perameles and Isoodon.","authors":"S M Walton","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 2","pages":"115-20"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16185107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130162
H E Wyandt, F Hecht, E W Lovrien, R E Stewart
{"title":"Study of a patient with apparent monosomy 21 owing to translocation: 45,XX,21-,t(18q+).","authors":"H E Wyandt, F Hecht, E W Lovrien, R E Stewart","doi":"10.1159/000130162","DOIUrl":"https://doi.org/10.1159/000130162","url":null,"abstract":"A five-year-old girl with mild mental retardation and dyschondrosteosis was found to have 45 chromosomes. A G (21-22) chromosome was missing. The parents were chromosomally normal. Measurements confirmed the presence of an unusually long chromosome No. 17 or 18 in the girl’s karyotypes. Late labeling with 3H-thymidine and autoradiography showed it to be No. 18. By quinacrine fluoromicroscopy the apparently missing G chromosome proved to be No. 21. Thus, the apparent autosomal monosomy was the result of a de novo 18/21 translocation with loss of the short arm and centromere of No. 21 and of material from the long arms of No. 18 or No. 21 or both equivalent to two thirds of a G long arm. Although no evidence was found for deletion of a genetic marker, heterozygosity at five gene loci (MNSs, Jk, Hp, PGM, and AcP) excluded their deletion. We suggest that other instances of apparent autosomal monosomy may on careful study be found to be the result of similarly subtle chromosome rearrangements.","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 6","pages":"413-26"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16233339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130163
A De Capoa, A Rocchi, D A Miller, O J Miller
{"title":"Autoradiographic study of DNA synthesis in homologous chromosomes distinguishable by morphology.","authors":"A De Capoa, A Rocchi, D A Miller, O J Miller","doi":"10.1159/000130163","DOIUrl":"https://doi.org/10.1159/000130163","url":null,"abstract":"Autoradiographic terminal labeling studies performed on leukocyte cultures of a man (A. de J.) and his son (H. de J.), both carriers of an enlarged satellite on a D-group chromosome, demonstrated that the morphological marker was a No. 15. Counts of grains on the long arms of the two chromosomes 15 showed that the marker chromosome was less heavily labeled than its normal homolog. This difference was highly significant in both cases. The marker chromosome was also shorter than its homolog, though not significantly so in one case. Possible interpretations of these findings, i.e., chromosomal polymorphism or autosomal lyonization, were discussed.","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 6","pages":"427-35"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16233340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130145
N S Ma, C E Gilmore
{"title":"Chromosomal abnormality in a phenotypically and clinically normal dog.","authors":"N S Ma, C E Gilmore","doi":"10.1159/000130145","DOIUrl":"https://doi.org/10.1159/000130145","url":null,"abstract":"A seven-month-old black female setter-retriever cross was found to have a modal chromosome number of 77 and an apparent centric fusion of two autosomes. Extensive clinical examinations were performed,","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 4","pages":"254-9"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130145","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16252594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytogeneticsPub Date : 1971-01-01DOI: 10.1159/000130148
A Iino
{"title":"Observations on human somatic chromosomes treated with hyaluronidase.","authors":"A Iino","doi":"10.1159/000130148","DOIUrl":"https://doi.org/10.1159/000130148","url":null,"abstract":"By means of hyaluronidase (1 mg in 100 ml of distilled water), the spiral structure of human somatic chromsomes was studied in cultured leukocytes. The number of chromonemata forming a chromatid is tw","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 4","pages":"286-94"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130148","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16213872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}