Cytogenetics最新文献

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The quinacrine fluorescence karyotype of Mus musculus and demonstration of strain differences in secondary constrictions. 小家鼠的醌荧光核型及继发性收缩的品系差异论证。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130164
V G Dev, M S Grewal, D A Miller, R E Kouri, J J Hutton, O J Miller
{"title":"The quinacrine fluorescence karyotype of Mus musculus and demonstration of strain differences in secondary constrictions.","authors":"V G Dev, M S Grewal, D A Miller, R E Kouri, J J Hutton, O J Miller","doi":"10.1159/000130164","DOIUrl":"https://doi.org/10.1159/000130164","url":null,"abstract":"In the mouse, virtually every autosome pair, and the X and Y, was identified by its distinctive fluorescent banding pattern after staining with quinacrine mustard. The karyotype was characterized further by measurement of orcein-stained chromosomes and autoradiographic analysis of terminal DNA replication. The autoradiographic identification of the X and Y chromosomes was confirmed by this technique. Fluorescent karyotype analysis of inbred strains and a series of Fx hybrids involving C57BL/6J revealed a polymorphism, the presence or absence of a prominent secondary constriction on any of four different chromosomes, which was probably inherited in a simple Mendelian fashion.","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 6","pages":"436-51"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130164","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15221804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Observations on the incidence of Robertsonian translocations and associated testicular changes in a flock of New Zealand Romney sheep. 观察罗伯逊易位的发生率和相关的睾丸变化在一群新西兰罗姆尼羊。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130146
A N Bruère, R A Mills
{"title":"Observations on the incidence of Robertsonian translocations and associated testicular changes in a flock of New Zealand Romney sheep.","authors":"A N Bruère, R A Mills","doi":"10.1159/000130146","DOIUrl":"https://doi.org/10.1159/000130146","url":null,"abstract":"In the present paper preliminary observations are described on the incidence of the Massey I Robertsonian translocation in Romney sheep. In the established “M” pedigree flock an incidence of 4.6% of translocation heterozygotes was found in 152 animals examined randomly, compared with no such translocation in 246 sheep of varying breed from several countries. From pedigree follow-up a total of 25 translocation animals were found in an overall total of 180 animals studied. The origin of the translocation can be traced to two other popular pedigree flocks, “BH” and “MDW”, so that it could be distributed extensively in the Romney breed in New Zealand. Five rams with the translocation found in the “M” pedigree flock also had testicular abnormalities. Only three rams with the translocation from the same flock had normal testes. It is suggested that a “sterility” gene, which manifests itself by incomplete testicular development, may be associated in some cases with the translocation chromosome or its homologues and be present in either translocation heterozygotes or nontranslocation-carrying animals. Ewes heterozygous for the translocation appeared phenotypically normal. From leukocyte cultures one translocation heterozygote ewe was shown to be a normal translocation mosaic. A phenotypically normal ewe was found also from the present survey with a second type of Robertsonian translocation (Massey II), involving two of the larger acrocentric chromsomes and distinct from the Massey I translocation.","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 4","pages":"260-72"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16213870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Autoradiographic studies of cytogenetic effects induced by UV-inactivated measles virus (fusion factor) in human cells. 紫外线灭活麻疹病毒(融合因子)诱导人细胞细胞遗传学效应的放射自显影研究。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130156
S Henry, M M Cohen, D T Karzon
{"title":"Autoradiographic studies of cytogenetic effects induced by UV-inactivated measles virus (fusion factor) in human cells.","authors":"S Henry, M M Cohen, D T Karzon","doi":"10.1159/000130156","DOIUrl":"https://doi.org/10.1159/000130156","url":null,"abstract":"Two types of extensive chromosome changes (pulverization and uncoiling) as well as a combination of these phenomena in the same cell were induced by exposure to UV-inactivated measles virus (FF). The","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 5","pages":"377-83"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130156","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16242952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A chromosomal analysis of 25-day-old pig embryos. 25日龄猪胚胎的染色体分析。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130159
J H Smith, T J Marlowe
{"title":"A chromosomal analysis of 25-day-old pig embryos.","authors":"J H Smith, T J Marlowe","doi":"10.1159/000130159","DOIUrl":"https://doi.org/10.1159/000130159","url":null,"abstract":"Nine phenotypically normal gilts were slaughtered on the 25th day following coitus, and the embryos were harvested and cultured for karyotypic analysis. A total of 76 embryos were recovered, 8 of whic","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 6","pages":"385-91"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16257242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Pachytene analysis of human acrocentric chromosomes. 人类顶心染色体的粗线素分析。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130125
V K Bordjadze, A Prokofieva-Belgovskaya
{"title":"Pachytene analysis of human acrocentric chromosomes.","authors":"V K Bordjadze, A Prokofieva-Belgovskaya","doi":"10.1159/000130125","DOIUrl":"https://doi.org/10.1159/000130125","url":null,"abstract":"Analysis of pachytene chromosomes in testicular tissue of 11 subjects was conducted. A total of 158 acrocentric bivalents from group D and 50 from group G were studied. It was established that each of these five acrocentric bivalents showed a characteristic chromomere pattern, that is, number, size, shape, staining intensity, and tendency to aggregation versus disaggregation between adjacent or homologous chromomeres. Specificity of chromomere organization in acrocentric bivalents at the pachytene stage might provide a basis for their identification.","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 1","pages":"38-49"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15214393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Cytogenetic analyses of wild sheep populations in northern Iran. 伊朗北部野生绵羊种群的细胞遗传学分析。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130135
C F Nadler, D M Lay, J D Hassinger
{"title":"Cytogenetic analyses of wild sheep populations in northern Iran.","authors":"C F Nadler, D M Lay, J D Hassinger","doi":"10.1159/000130135","DOIUrl":"https://doi.org/10.1159/000130135","url":null,"abstract":"Seven populations of wild sheep ( Ovis ammon ) were studied in northern Iran. Analysis of 34 individuals demonstrated that the eastern populations possess a 2n = 58, including 1 pair","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 2","pages":"137-52"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130135","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16185111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 45
Sex-chromatin formation in pre-implantation rabbit embryos. 着床前兔胚胎的性染色质形成。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130144
F Plotnick, H P Klinger, A L Kosseff
{"title":"Sex-chromatin formation in pre-implantation rabbit embryos.","authors":"F Plotnick, H P Klinger, A L Kosseff","doi":"10.1159/000130144","DOIUrl":"https://doi.org/10.1159/000130144","url":null,"abstract":"Sex-chromatin frequency and cell number were determined for 250 rabbit embryos recovered 58 to 136 h after fertilization and consisting each of about 40 to 23,000 cells. Of the 37 embryos recovered up","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 4","pages":"244-53"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16213869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Comparison of chromosomal behavior in cultured lymphocytes and fibroblasts from patients with chromosomal disorders and controls. 染色体疾病患者与对照组培养淋巴细胞和成纤维细胞染色体行为的比较。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130147
M Higurashi, P E Conen
{"title":"Comparison of chromosomal behavior in cultured lymphocytes and fibroblasts from patients with chromosomal disorders and controls.","authors":"M Higurashi, P E Conen","doi":"10.1159/000130147","DOIUrl":"https://doi.org/10.1159/000130147","url":null,"abstract":"The occurrence of satellite association, breaks, tetraploidy or endoreduplication, and structural rearrangements was studied and compared in 600 lymphocyte and 600 skin-fibroblast metaphases from 30 k","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 4","pages":"273-85"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16213871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Tetraploidy and 18-trisomy in a six-year-old triple mosaic boy. 六岁三嵌合男孩的四倍体和18-三体。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130150
R L Atnip, R L Summitt
{"title":"Tetraploidy and 18-trisomy in a six-year-old triple mosaic boy.","authors":"R L Atnip, R L Summitt","doi":"10.1159/000130150","DOIUrl":"https://doi.org/10.1159/000130150","url":null,"abstract":"Clinical and cytogenetic studies of a six-year-old boy with multiple anomalies, including growth retardation, mild mental retardation, diffusely scattered minute areas of skin hypopigmentation, and sk","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 5","pages":"305-17"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16242948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Quinacrine fluorescent karyotypes of human diploid and heteroploid cell lines. 人二倍体和异倍体细胞系的Quinacrine荧光核型。
Cytogenetics Pub Date : 1971-01-01 DOI: 10.1159/000130152
O J Miller, D A Miller, P W Allderdice, V G Dev, M S Grewal
{"title":"Quinacrine fluorescent karyotypes of human diploid and heteroploid cell lines.","authors":"O J Miller, D A Miller, P W Allderdice, V G Dev, M S Grewal","doi":"10.1159/000130152","DOIUrl":"https://doi.org/10.1159/000130152","url":null,"abstract":"Quinacrine-fluorescence karyotypes were prepared on a series of human cell lines. WI-38 karyotypes were indistinguishable from those obtained from cultured XX blood leukocytes. WI-L2 lymphoblastoid ce","PeriodicalId":78202,"journal":{"name":"Cytogenetics","volume":"10 5","pages":"338-46"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000130152","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16242950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 90
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