María López-Díaz , Ester Fernández Díaz , Indalecio Cano Novillo , Elena Bergón , Rocío Morante Valverde , Alberto Galindo Izquierdo , Juan L. Antón-Pacheco
{"title":"Malformaciones pulmonares congénitas: ¿Qué impacto tiene la presencia de síntomas preoperatorios en el resultado quirúrgico?","authors":"María López-Díaz , Ester Fernández Díaz , Indalecio Cano Novillo , Elena Bergón , Rocío Morante Valverde , Alberto Galindo Izquierdo , Juan L. Antón-Pacheco","doi":"10.1016/j.anpedi.2025.503835","DOIUrl":"10.1016/j.anpedi.2025.503835","url":null,"abstract":"<div><h3>Introduction</h3><div>The management of congenital lung malformations (CLMs) is controversial because most of them are asymptomatic. The aim of our study was to analyze the association of preoperative symptoms with surgical outcomes in patients with CLMs treated by means of minimally invasive surgery (MIS).</div></div><div><h3>Patients and methods</h3><div>Retrospective study of patients with CLM treated with MIS in our hospital between 2003 and 2023. We recorded data on the following variables: demographic characteristics, size, type and location of the lesion, mediastinal shift, clinical symptoms, surgical time, conversion to open surgery, duration of chest drainage (days), length of stay and postoperative complications.</div></div><div><h3>Results</h3><div>The sample included 116 patients, 98 (84.4%) asymptomatic and 18 (15.5%) with clinically significant symptom: infectious in 10 (55.5%) and respiratory distress in eight. The most frequent histopathological type was congenital pulmonary airway malformation (35.5%), followed by intralobar sequestration (27.3%), and the lower lobes were most commonly involved (78.4%). Larger lesion size on the CT scan was significantly associated with the development of symptoms (<em>P</em> <!-->=<!--> <!-->.027) and with an increased frequency of conversion to open surgery. However, the incidence of postoperative complications was not greater in the symptomatic group.</div></div><div><h3>Conclusions</h3><div>Postoperative complications were not significantly more frequent in the symptomatic group of patients. Larger lesion size on imaging was associated with a significantly increased probability of developing symptoms, so these patients may benefit from early surgical resection.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503835"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Almudena Alonso-Ojembarrena , Rebeca Gregorio-Hernández , Manuel Sánchez-Luna
{"title":"Registro nacional multicéntrico sobre ecografía pulmonar en el menor de 26 semanas (MINI-LUS)","authors":"Almudena Alonso-Ojembarrena , Rebeca Gregorio-Hernández , Manuel Sánchez-Luna","doi":"10.1016/j.anpedi.2025.503837","DOIUrl":"10.1016/j.anpedi.2025.503837","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503837"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Marcilla Vázquez , Juan Ríos Laorden , Ángeles Lloret Callejo , Francisco Tejada Cifuentes , María José Tirado Peláez , Ignacio Párraga-Martínez
{"title":"Evolución de prescripción antibiótica en Atención Primaria según indicadores del PRAN (Plan Nacional frente a la Resistencia a los Antibióticos)","authors":"Carlos Marcilla Vázquez , Juan Ríos Laorden , Ángeles Lloret Callejo , Francisco Tejada Cifuentes , María José Tirado Peláez , Ignacio Párraga-Martínez","doi":"10.1016/j.anpedi.2025.503840","DOIUrl":"10.1016/j.anpedi.2025.503840","url":null,"abstract":"<div><h3>Introduction</h3><div>Spain is the fourth European country with the highest antibiotic consumption at the community level, and children aged 0 to 4 years are one of the age groups with the highest consumption. The aim of our study was to analyze the evolution of antibiotic prescribing in the paediatric catchment population of a primary care area in Spain according to the indicators established in the National Plan against Antibiotic Resistance (PRAN) over 10<!--> <!-->years (2014-2023) and to assess the impact of the COVID-19 pandemic by comparing the 2020-2021 period with the preceding and subsequent periods (2014-2019 and 2022-2023).</div></div><div><h3>Material and methods</h3><div>Retrospective observational study of the prescribing of antibiotics for systemic use (J01 group of the Anatomical Therapeutic Chemical Classification) in paediatric patients (0-14 years) covered by the primary care system of the Albacete health care administration between 2014 and 2023.</div></div><div><h3>Results</h3><div>The mean antibiotic prescription was 16.90 defined daily doses (DDD) per 1000 inhabitants per day and 12.10 DOT (days of therapy). The corresponding values in the prepandemic period (2014-2019) were 19.32 DDD/1000 inhabitants/day and 13.92 DOT, which decreased to 8.30 DDD/1000 inhabitants/day and 6.05 DOT during the pandemic (2020-2021) and then increased to 18.05 DDD/1000 inhabitants/day and 12.40 DOT in the pospandemic period (2022-2023). There was an improvement in appropriate prescribing after the COVID-19 pandemic, with a reduction in the consumption of amoxicillin-clavulanic acid and greater consumption of penicillin and amoxicillin during prepandemic and pandemic years (<em>P</em> <<!--> <!-->.05).</div></div><div><h3>Conclusions</h3><div>Throughout the study period, there was improvement in the consumption indicators established in the PRAN, with an increase in the use of beta-lactamase sensitive penicillins and amoxicillin and a reduction in the use of amoxicillin-clavulanic acid.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503840"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Font Roset , Isabel Sánchez Bueno , Anton Foguet Vidal , Stephan Otto Schneider
{"title":"Poliorquidismo: un hallazgo ecográfico poco frecuente","authors":"Maria Font Roset , Isabel Sánchez Bueno , Anton Foguet Vidal , Stephan Otto Schneider","doi":"10.1016/j.anpedi.2025.503769","DOIUrl":"10.1016/j.anpedi.2025.503769","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503769"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Catarino , Lídia Carvalho , Angélica Ramos , Manuela Rodrigues , Ana Reis-Melo
{"title":"Sífilis congénita en aumento. Revisión de 5 años en un hospital de referencia en Portugal","authors":"Sara Catarino , Lídia Carvalho , Angélica Ramos , Manuela Rodrigues , Ana Reis-Melo","doi":"10.1016/j.anpedi.2025.503800","DOIUrl":"10.1016/j.anpedi.2025.503800","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503800"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Israel Pérez-López, Marta Cebolla-Verdugo, Ricardo Ruiz-Villaverde
{"title":"Flebolitos como marcador radiológico de malformación venosa","authors":"Israel Pérez-López, Marta Cebolla-Verdugo, Ricardo Ruiz-Villaverde","doi":"10.1016/j.anpedi.2024.503748","DOIUrl":"10.1016/j.anpedi.2024.503748","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503748"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Al-wattar-Ceballos, Marina Montero-García, Mónica Gómez-Manzanares, Carlos Mendoza-Chaparro
{"title":"Herpes-zóster en un paciente vacunado recientemente de varicela","authors":"Omar Al-wattar-Ceballos, Marina Montero-García, Mónica Gómez-Manzanares, Carlos Mendoza-Chaparro","doi":"10.1016/j.anpedi.2024.503723","DOIUrl":"10.1016/j.anpedi.2024.503723","url":null,"abstract":"","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503723"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Dolores Pastor-Vivero , Jordi Costa i Colomer , Carlos Martín de Vicente , Saioa Vicente-Santamaria , Ruth García Romero , David González Jiménez , Carmen Luna Paredes
{"title":"Avances en el tratamiento de la fibrosis quística: los moduladores de la CFTR","authors":"Maria Dolores Pastor-Vivero , Jordi Costa i Colomer , Carlos Martín de Vicente , Saioa Vicente-Santamaria , Ruth García Romero , David González Jiménez , Carmen Luna Paredes","doi":"10.1016/j.anpedi.2025.503857","DOIUrl":"10.1016/j.anpedi.2025.503857","url":null,"abstract":"<div><div>Cystic fibrosis is a severe genetic disease caused by variants in the <em>CFTR</em> gene. Although it is a multisystem disease, respiratory involvement is the main cause of morbidity and mortality. Cystic fibrosis transmembrane conductance regulator modulator (CFTRm) therapies have advanced the treatment of this disease by improving function of this protein. Ivacaftor, the first CFTRm, has been found to significantly improve lung function and quality of life in patients with certain gating variants. However, only a small percentage of patients in Spain are eligible for this treatment. Combinations of correctors and potentiators, such as lumacaftor-ivacaftor or tezacaftor-ivacaftor, have been developed for treatment of patients with the most frequent variant (F508del), although with limited benefits. Triple therapy with elexacaftor-tezacaftor-ivacaftor has been found to significantly improve respiratory, gastrointestinal and nutritional outcomes as well as quality of life, thus changing the management of CF in eligible patients. The impact of triple therapy is also reflected in an increase in life expectancy and a decrease in mortality and lung transplantation. As regards hepatic and pancreatic involvement, while CFTR modulators have exhibited promising effects, further research is required. The use of CFTR modulators has also shifted nutritional status trends in patients with CF, reducing the risk of undernutrition but increasing the risk of obesity. The use of these drugs for treatment of less frequent variants and for potential antenatal treatment is currently being investigated. Despite these advances, there is still a subset of patients who are ineligible for treatment with modulators or highly effective therapy.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 5","pages":"Article 503857"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Consentimiento sexual en la adolescencia. Influencia del consumo de la «nueva pornografia» en la toma de decisiones","authors":"Ester Barrios Miras , Montserrat Esquerda Areste","doi":"10.1016/j.anpedi.2025.503791","DOIUrl":"10.1016/j.anpedi.2025.503791","url":null,"abstract":"<div><div>Adolescence is a transitional stage of development, with imprecise age limits, during which the individual progressively develops the maturity required for decision-making. Sexual consent is part of the right to sexual freedom, a fundamental right that must be promoted and taught from childhood. At present, there is considerable social alarm in relation to the risks associated with the increased consumption of pornography from an early age. Pornography provides a distorted image of sexual relations that does not feature the elements of consent or respect to the other, commonly offering visual content that normalizes violence, humiliation and the objectification of human beings. The lack of comprehensive sex education with an affective component, combined with the emergence of “new pornograph” as a school of sexuality, means that adolescents may come to accept and/or normalize nonconsensual sexual relations that can violate the dignity of the individual. The aim of the study was to perform a critical review of the literature available in the main databases published from 2015 to present in order to characterize the consumption of pornography by adolescents and its associated risks. Lastly, it addresses individual and social factors involved in sexual consent, as well as aspects related to the autonomy required for the individual to be able to consent.</div></div>","PeriodicalId":7783,"journal":{"name":"Anales de pediatria","volume":"102 4","pages":"Article 503791"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}