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Revista espanola de oncologia最新文献

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[Preliminary information on a new technic for the determination of circulating immunocomplexes using L1210 cells and immunoenzyme analysis. Observations in patients with cancer]. 使用L1210细胞和免疫酶分析测定循环免疫复合物新技术的初步信息。癌症患者的观察[j]。
Revista espanola de oncologia Pub Date : 1985-01-01
J Castellanos, Y Alvarez-Rodríguez, M P Valladares
{"title":"[Preliminary information on a new technic for the determination of circulating immunocomplexes using L1210 cells and immunoenzyme analysis. Observations in patients with cancer].","authors":"J Castellanos, Y Alvarez-Rodríguez, M P Valladares","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 4","pages":"583-93"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14995835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Design and synthesis of conjugates between antineoplastic agents and monoclonal antibodies]. 抗肿瘤药物与单克隆抗体偶联物的设计与合成
Revista espanola de oncologia Pub Date : 1985-01-01
J Gallego, M Ribas i Mundó
{"title":"[Design and synthesis of conjugates between antineoplastic agents and monoclonal antibodies].","authors":"J Gallego,&nbsp;M Ribas i Mundó","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The production of conjugates between anti-tumor agents and monoclonal antibodies in order to achieve a more selective therapy of cancer has been a research field in continuous expansion during the last years. The present study is directed towards trying to define a practice guide to be used in the design and synthesis of this type of conjugates. The points considered refer to the characteristics which have to be taken into account of each of the parts which constitute the conjugate (monoclonal antibody or fragments and the anti-tumor agent) and also of the method of synthesis, according to our experience and experience gained in other laboratories. The qualities studied of the antibody are its specificity towards tumour cells, intrinsic cytotoxicity, molecular size, antigenicity, resistance to manipulation, biological half life and antigenic modulation properties. Referent to the cytotoxic agent the properties to deal with are its toxicity, presence of functional groups, hydrophobicity, ionic charge, unspecific interaction sites, molecular weight, resistance to manipulation and antigenicity. The characteristics to take into account of the method of synthesis are its simplicity, the homogeneity of the products obtained, the difficulty in purifying the products, the smoothness of the reaction and the type of conjugate formed (that is, whether the agent has been directly linked to the antibody or linked to it via a \"bridge\" molecule). The ideal characteristics referring to every one of these points have been selected having in mind the possibility of clinical application of this type of conjugates that we expect to have a specific cytotoxic action on tumour cells once the antibody has been selectively localized in the tumour and has targeted there the cytotoxic agent coupled to it. Some of the points studied are, however, still open to further evaluation.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 1","pages":"117-28"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13583609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Neuron-specific serum enolase in patients with non-tumor pathologies]. 【非肿瘤病理患者的神经元特异性血清烯醇化酶】。
Revista espanola de oncologia Pub Date : 1985-01-01
A Ruibal, G Encabo, J Genollá, S Mañé, E M Miralles
{"title":"[Neuron-specific serum enolase in patients with non-tumor pathologies].","authors":"A Ruibal,&nbsp;G Encabo,&nbsp;J Genollá,&nbsp;S Mañé,&nbsp;E M Miralles","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this brief communication, the authors indicate that amounts of neuron-specific enolase higher than 30 ng/ml are observed only in 1% of non-tumoral processes, and that when found in patients with respiratory symptoms a microcytic carcinoma of the lung can be suspected in 97% of the cases.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 1","pages":"183-6"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14959483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Serum levels of sialoglycoproteins soluble in perchloric acid in rats with Yoshida's sarcoma]. [吉田肉瘤大鼠高氯酸可溶性唾液糖蛋白的血清水平]。
Revista espanola de oncologia Pub Date : 1985-01-01
E Osinaga, S Lara Baruque, L Cifuentes de Castro
{"title":"[Serum levels of sialoglycoproteins soluble in perchloric acid in rats with Yoshida's sarcoma].","authors":"E Osinaga,&nbsp;S Lara Baruque,&nbsp;L Cifuentes de Castro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have studied the levels of sialo-glycoprotein in the serum of Yoshida sarcoma-bearing rats, with the aim of exploring its possible value as a tumour marker and the influence upon it of non-neoplastic factors.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 2","pages":"291-300"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14960702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinico-hematic study of lymphoblastic leukemia of childhood]. [儿童淋巴细胞白血病的临床-血液研究]。
Revista espanola de oncologia Pub Date : 1985-01-01
V Muñoz Rodríguez, I Consuegra Ordaz, E Cristo Morón, O Fernández Ramos
{"title":"[Clinico-hematic study of lymphoblastic leukemia of childhood].","authors":"V Muñoz Rodríguez,&nbsp;I Consuegra Ordaz,&nbsp;E Cristo Morón,&nbsp;O Fernández Ramos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors write their personal experience in 205 children with lymphoblastic leukemia. The disease has its peak incidence between 5 and 14 years, showing a preference for females and white individuals. The clinical form of presentation was \"complete\" (66.8%) or \"incomplete\" (33.2%). Most of the symptoms were due to leukemic infiltration of bone marrow and some other tissues. The amount of leukocytes was variable; most of the cases showed anemia and thrombocytopenia. However, a few patients had normal values of hemoglobin and platelets, whose prognostic significance is discussed. After the FAB classification, the L1 variety predominated. About 3.9% of the patients showed radiological bone alterations suggesting acute leukemia.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 1","pages":"85-94"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14984736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gastric carcinoma in Cantabria: III. Anatomo-pathological factors of prognostic significance]. 坎塔布利亚胃癌:3。解剖病理因素的预后意义]。
Revista espanola de oncologia Pub Date : 1985-01-01
C Blanco García, J F Val Bernal
{"title":"[Gastric carcinoma in Cantabria: III. Anatomo-pathological factors of prognostic significance].","authors":"C Blanco García,&nbsp;J F Val Bernal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present study, we have proceeded to analyze different anatomo-pathological parametres concerning 638 gastric carcinomas, for a twelve year period between 1970-1981, such as location and macroscopic aspect, tumoral extension and histological type, observing their prognosis in the case of curative surgery. We have also proceeded to analyze the rate of survival amounting to 5 years in all the patients being examined, depending on the therapeutical attitude in use. We then proceeded to compare our series with others already published, thus coinciding in the best prognosis as to tumoral location in antrum-pylorus with an ulcerated aspect, less depth as to intraparietal invasion, as well as an absence of ganglionar compromise and visceral metastasis. We also proceeded to analyze the rate of survival concerning the histological type, according to WHO classification.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"507-18"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14987358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Normal and pathological distribution of 131-m-iodobenzylguanidine in children. Contribution to the diagnosis of neuroblastoma]. 131-m-碘苄基胍在儿童中的正常与病理分布。对神经母细胞瘤诊断的贡献[j]。
Revista espanola de oncologia Pub Date : 1985-01-01
J Ferris, O Caballero, A Verdaguer, C Esquembre, V Castel
{"title":"[Normal and pathological distribution of 131-m-iodobenzylguanidine in children. Contribution to the diagnosis of neuroblastoma].","authors":"J Ferris,&nbsp;O Caballero,&nbsp;A Verdaguer,&nbsp;C Esquembre,&nbsp;V Castel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study is made about the normal and abnormal gammagraphic patterns with 131-I-metaiodobenzylguanidine for the diagnosis of neuroblastoma in children. The authors find 100 per 100 positive results.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"519-28"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14987359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of dexamethasone at the level of cerebral metastases. Evaluation by CT and nuclear medicine]. 地塞米松对脑转移瘤水平的影响。CT与核医学评价]。
Revista espanola de oncologia Pub Date : 1985-01-01
S Bascuas Meliz, M T Gutiérrez Amares, L Machuca Munoz, J L Bascuas Asta
{"title":"[Effect of dexamethasone at the level of cerebral metastases. Evaluation by CT and nuclear medicine].","authors":"S Bascuas Meliz,&nbsp;M T Gutiérrez Amares,&nbsp;L Machuca Munoz,&nbsp;J L Bascuas Asta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thirty five patients with brain metastases and edema were treated with dexamethasone. The results were evaluated by cranial computed tomography and nuclear medicine. Edema was alleviated in 32 out of the 35 patients after a two weeks treatment.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"539-42"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14987360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Indications for radiotherapy in the superior vena cava syndrome]. 上腔静脉综合征放疗的适应症。
Revista espanola de oncologia Pub Date : 1985-01-01
J Torras Roselló, S Ripol Girona
{"title":"[Indications for radiotherapy in the superior vena cava syndrome].","authors":"J Torras Roselló,&nbsp;S Ripol Girona","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of radiotherapy upon the superior vena cava syndrome is studied. The treatment is never curative and the patients survive between 3 and 13 months, but it is useful in 80 per 100 of the cases to alleviate the edema and dyspnea that are always grave.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 3","pages":"543-50"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14987362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Colposcopy and early diagnosis of cancer of the uterine cervix]. 阴道镜检查与子宫颈癌的早期诊断
Revista espanola de oncologia Pub Date : 1985-01-01
N López García, S Recio Sánchez, A García Gallego
{"title":"[Colposcopy and early diagnosis of cancer of the uterine cervix].","authors":"N López García,&nbsp;S Recio Sánchez,&nbsp;A García Gallego","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This work shows the indications, procedure, and usefulness of colposcopy in the early detection of cervical carcinoma. Colposcopy is very useful, and 20 per 100 of the false positive cases are generally corrected by the cytological study. The combined use of cytology and colposcopy attains the early diagnosis of most cases of preclinical carcinoma of the cervix.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"32 4","pages":"671-80"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14997156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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