Annales de l'Institut Pasteur. Immunology最新文献_第5页

2es Journées internationales de biologie médicale et de biotechnologie 第二届国际医学生物学和生物技术日

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-09-01 DOI: 10.1016/0769-2625(88)90122-5

引用次数: 0

Trois réunions sur le thème du cancer 三次关于癌症的会议

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-09-01 DOI: 10.1016/0769-2625(88)90113-4

引用次数: 0

Immune recognition of cytochrome c I. — Molecular requirements for antibody recognition and immune response stimulation studied in vitro with synthetic peptides 细胞色素c的免疫识别——体外合成肽对抗体识别和免疫反应刺激的分子要求研究

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-09-01 DOI: 10.1016/0769-2625(88)90097-9

S.V Komissarenko , M.V Skok , E.M Kavoon , V.S Chudnovets , R.P Evstigneeva

{"title":"Immune recognition of cytochrome c I. — Molecular requirements for antibody recognition and immune response stimulation studied in vitro with synthetic peptides","authors":"S.V Komissarenko , M.V Skok , E.M Kavoon , V.S Chudnovets , R.P Evstigneeva","doi":"10.1016/0769-2625(88)90097-9","DOIUrl":"10.1016/0769-2625(88)90097-9","url":null,"abstract":"<div>The epitope specificity of antibodies to horse cytochrome c (cyt.c) in the primary and secondary immune response of C57BL mice was studied by means of the ELISA technique with synthetic peptides of cyt.c. It was found that, in the early primary response, N- and C-end fragments of cyt.c (peptides 2–13, 14–22 and 92–104) were preferentially recognized. In the secondary response, more antibodies to the epitopes of the central part of the molecule (peptides 61–69 and 46–56) were found. This was presumed to be due to the mode of cyt.c processing and presentation in the course of immune response: at first, cyt.c was recognized in the native form and then in the processed one. The capacity of cyt.c peptides to stimulate the formation of cyt.c-specific antibody-secreting cells (ASC) was studied in splenocyte culture of C57BL mice. Peptides stimulated more ASC than cyt.c did, but larger molar doses of peptides were required. Comparison of the capacity of related peptides (1–13 and 2–13, 61–69, 61–77 and 57–77) to be recognized by antibodies produced to native cyt.cin vivo and to stimulate anti-cyt.c ASC in vitro suggested certain molecular requirements for cyt.c epitope and agretope formation. These were partially confirmed by computer analysis.</div>","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 5","pages":"Pages 517-530"},"PeriodicalIF":0.0,"publicationDate":"1988-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90097-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13610310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Structure and function of a thymic peptide is mimicked by Plasmodium falciparum peptides 一种胸腺肽的结构和功能被恶性疟原虫肽所模仿

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-09-01 DOI: 10.1016/0769-2625(88)90100-6

P. Dubois , M. Dardenne , T. Fandeur , O. Mercereau-Puijalon , D. Mattei , B. Müller-Hill , T. Blisnick , L. Pereira da Silva

引用次数: 10

Immunopathologie chez le chien et le chat 狗和猫的免疫病理学

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-09-01 DOI: 10.1016/0769-2625(88)90116-X

引用次数: 0

Polymorphism of the seventh component of complement (C7) in a healthy caucasian population: An immunoblotting study with neuraminidase-treated samples 健康高加索人群补体第七组分(C7)多态性:神经氨酸酶处理样本的免疫印迹研究

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-09-01 DOI: 10.1016/0769-2625(88)90096-7

G Dewald

引用次数: 3

Isolation of an antiidiotypic antibody with acetylcholine-receptor-like binding properties from myasthenia gravis patients 重症肌无力患者乙酰胆碱受体样结合抗独特型抗体的分离

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-09-01 DOI: 10.1016/0769-2625(88)90101-8

H Eng, A.K Lefvert

引用次数: 8

Enseignement de statistique en médecine, épidémiologie et biologie 医学、流行病学和生物学统计学教学

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-07-01 DOI: 10.1016/0769-2625(88)90093-1

引用次数: 0

Le diagnostic et la lutte contre le SIDA: la situation actuelle 艾滋病的诊断和防治:现状

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-07-01 DOI: 10.1016/0769-2625(88)90080-3

引用次数: 0

4e symposium d'immunodermatologie 免疫皮肤病学研讨会

Annales de l'Institut Pasteur. Immunology Pub Date : 1988-07-01 DOI: 10.1016/0769-2625(88)90085-2

引用次数: 0