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Annales de l'Institut Pasteur. Immunology最新文献

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Techniques immunoenzymatiques immunoenzymatiques技术
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90154-7
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引用次数: 0
Endogenous and exogenous TNF therapy (EET therapy): conceptual and experimental grounds. 内源性和外源性TNF治疗(EET治疗):概念和实验依据。
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01
D Mizuno, G I Soma
{"title":"Endogenous and exogenous TNF therapy (EET therapy): conceptual and experimental grounds.","authors":"D Mizuno, G I Soma","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"282-5"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14180752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural lymphocyte activation in postnatal development of germ-free and conventional mice 天然淋巴细胞活化在无菌和常规小鼠出生后发育中的作用
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90138-9
L. Forni , C. Heusser , A. Coutinho
{"title":"Natural lymphocyte activation in postnatal development of germ-free and conventional mice","authors":"L. Forni ,&nbsp;C. Heusser ,&nbsp;A. Coutinho","doi":"10.1016/0769-2625(88)90138-9","DOIUrl":"10.1016/0769-2625(88)90138-9","url":null,"abstract":"<div><p>The degree of activation of B and T cells in the developing spleen during postnatal life was studied in germ-free (GF) and specific-pathogen-free (SPF) BALB/c mice of the same breeding stock. We found that the progeny of GF mothers up to 3 weeks of age contain higher numbers of activated splenic cells than baby SPF mice, thus suggesting qualitative differences in maternally-derived antibodies. This «advantageå of GF mice is also indicated by anticipated maturation of the splenic lymphoid compartment and is reflected in higher frequencies of B and T lymphocytes in adult life.</p><p>In both kinds of mice, the frequency of activated cells is very high at birth and then declines, reaching minimal valyes by 4 weeks of age. Later, activated B cells increase sharply in SPF mice, suggesting polyclonal activation mediated by bacterial products. Results are discussed on the basis of the mutual influences between B and T cells in the establishment of a functional network.</p></div>","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"Pages 245-256"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90138-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14391528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
23rd forum in immunology. Non-specific lymphoid effectors: characterization and activation mechanisms. 第23届免疫学论坛。非特异性淋巴效应器:表征和激活机制。
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01
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引用次数: 0
In vivo anti-tumour activity of recombinant human tumour necrosis factor-alpha against Meth-A sarcoma requires L3T4-positive T cells 重组人肿瘤坏死因子- α对甲基a型肉瘤的体内抗肿瘤活性需要l3t4阳性T细胞
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90144-4
M.A. Palladino, I.S. Figari
{"title":"In vivo anti-tumour activity of recombinant human tumour necrosis factor-alpha against Meth-A sarcoma requires L3T4-positive T cells","authors":"M.A. Palladino,&nbsp;I.S. Figari","doi":"10.1016/0769-2625(88)90144-4","DOIUrl":"10.1016/0769-2625(88)90144-4","url":null,"abstract":"","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"Pages 299-301"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90144-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14038914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Nuclear location of the p55 subunit of the IL-2 receptor following activation of the HT-2 T helper cell line ht - 2t辅助细胞系激活后IL-2受体p55亚基的核定位
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90137-7
S. Jothy , A. Abadie , P. Froussard , M. Duphot , J. Thèze
{"title":"Nuclear location of the p55 subunit of the IL-2 receptor following activation of the HT-2 T helper cell line","authors":"S. Jothy ,&nbsp;A. Abadie ,&nbsp;P. Froussard ,&nbsp;M. Duphot ,&nbsp;J. Thèze","doi":"10.1016/0769-2625(88)90137-7","DOIUrl":"10.1016/0769-2625(88)90137-7","url":null,"abstract":"<div><p>After mitogenic or antigenic stimulation, T cells express interleukin-2 receptors (IL-2R). The mechanism and control of signal transduction following binding of IL-2 to IL-2R are poorly understood.</p><p>Using two rat monoclonal antibodies (5A2 and 7D4) specific for two distinct epitopes of the p55 subunit of mouse IL-2R, we have studied the cellular localization of this molecule by immunocytochemistry during the IL-2-mediated activation of mouse T helper cell clone HT-2. During the activation cycle, nuclear staining for the p55 subunit of the IL-2 receptor was transiently observed. It is suggested that the transient nuclear location of the IL-2R may play a critical role in the control of T-cell activation, proliferation and/or differentiation.</p></div>","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"Pages 237-244"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90137-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14105546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
TNF as an activator of vascular endothelium TNF作为血管内皮的激活剂
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90149-3
J.S. Pober
{"title":"TNF as an activator of vascular endothelium","authors":"J.S. Pober","doi":"10.1016/0769-2625(88)90149-3","DOIUrl":"10.1016/0769-2625(88)90149-3","url":null,"abstract":"","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"Pages 317-323"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90149-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14180759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 33
Sensitizing effects and mechanisms of desensitization in regulation of the in vivo response to TNF 致敏效应和脱敏机制在调节TNF体内反应中的作用
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90150-X
D. Wallach, H. Holtmann, D. Aderka, T. Hahn, H. Engelmann, Y. Nophar
{"title":"Sensitizing effects and mechanisms of desensitization in regulation of the in vivo response to TNF","authors":"D. Wallach,&nbsp;H. Holtmann,&nbsp;D. Aderka,&nbsp;T. Hahn,&nbsp;H. Engelmann,&nbsp;Y. Nophar","doi":"10.1016/0769-2625(88)90150-X","DOIUrl":"10.1016/0769-2625(88)90150-X","url":null,"abstract":"","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"Pages 323-327"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90150-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14180760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Sjögren's syndrome clinical and immunological aspects Sjögren's综合征的临床和免疫学方面
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90160-2
G. Dighiero
{"title":"Sjögren's syndrome clinical and immunological aspects","authors":"G. Dighiero","doi":"10.1016/0769-2625(88)90160-2","DOIUrl":"10.1016/0769-2625(88)90160-2","url":null,"abstract":"","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"Page 345"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90160-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"95944904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells 辅助T细胞失活后，克氏锥虫感染小鼠的寄生负荷增加，心肌炎症减少
Annales de l'Institut Pasteur. Immunology Pub Date : 1988-05-01 DOI: 10.1016/0769-2625(88)90136-5
M. Russo , N. Starobinas , P. Minoprio , A. Coutinho , M. Hontebeyrie-Joskowicz
{"title":"Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells","authors":"M. Russo ,&nbsp;N. Starobinas ,&nbsp;P. Minoprio ,&nbsp;A. Coutinho ,&nbsp;M. Hontebeyrie-Joskowicz","doi":"10.1016/0769-2625(88)90136-5","DOIUrl":"10.1016/0769-2625(88)90136-5","url":null,"abstract":"<div><p>In order to characterize the role played by CD4<sup>+</sup> T lymphocytes in the immunopathology of acute <em>Trypanosoma cruzi</em> infection, we compared the numbers of blood and tissue parasites and the heart inflammatory reaction in normal and anti-CD4 antibody-treated C3H mice. Treatment of mice with anti-CD4 mAb during acute infection markedly inhibited T-helper-cell-dependent activities, as measured by peritoneal macrophage activation and immunoglobulin secretion by splenic B lymphocytes. After <em>in vivo</em> inactivation of helper T cells, the number of blood and tissue parasites significantly increased, while the inflammatory cellular infiltrates of heart muscles diminished.</p><p>Our results indicate that CD4<sup>+</sup> T lymphocytes play a dual role in the immunopathology of acute experimental Chagas' disease.</p></div>","PeriodicalId":77665,"journal":{"name":"Annales de l'Institut Pasteur. Immunology","volume":"139 3","pages":"Pages 225-236"},"PeriodicalIF":0.0,"publicationDate":"1988-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0769-2625(88)90136-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14038913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 79
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