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Atezolizumab-Associated Retiform Purpura. 阿特珠单抗相关视网膜紫癜
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 Epub Date: 2024-02-09 DOI: 10.1097/MJT.0000000000001665
Sabeen Sidiki, Rawish Fatima, Nahimarys Colón Hernández, Nezam Altorok
{"title":"Atezolizumab-Associated Retiform Purpura.","authors":"Sabeen Sidiki, Rawish Fatima, Nahimarys Colón Hernández, Nezam Altorok","doi":"10.1097/MJT.0000000000001665","DOIUrl":"10.1097/MJT.0000000000001665","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e455-e458"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139711256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guanfacine Used With Antipsychotics May Cause Bradycardia to Become Apparent After Discontinuation of Antipsychotics. 关法辛与抗精神病药物合用可能导致停用抗精神病药物后出现心动过缓。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 Epub Date: 2024-01-18 DOI: 10.1097/MJT.0000000000001654
Tsukasa Murata, Katsuaki Uno, Takahiko Nagamine
{"title":"Guanfacine Used With Antipsychotics May Cause Bradycardia to Become Apparent After Discontinuation of Antipsychotics.","authors":"Tsukasa Murata, Katsuaki Uno, Takahiko Nagamine","doi":"10.1097/MJT.0000000000001654","DOIUrl":"10.1097/MJT.0000000000001654","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e440-e444"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139501804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lithium Hemodialysis Removal-Related Recurrent Manic Episode in a Bipolar Patient. 一名躁郁症患者因锂离子血液透析去除导致的复发性躁狂发作。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 Epub Date: 2021-04-29 DOI: 10.1097/MJT.0000000000001382
Hung-Yi Lin, Fan-Hsuan Kung, Yueh-Ming Tai, San-Yuan Huang, Yu-Juei Hsu, Nian-Sheng Tzeng
{"title":"Lithium Hemodialysis Removal-Related Recurrent Manic Episode in a Bipolar Patient.","authors":"Hung-Yi Lin, Fan-Hsuan Kung, Yueh-Ming Tai, San-Yuan Huang, Yu-Juei Hsu, Nian-Sheng Tzeng","doi":"10.1097/MJT.0000000000001382","DOIUrl":"10.1097/MJT.0000000000001382","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e420-e421"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38999087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Favipiravir for the Treatment of Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 法维拉韦治疗 COVID-19 住院患者：随机对照试验的系统回顾和元分析》。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 Epub Date: 2024-01-23 DOI: 10.1097/MJT.0000000000001688
Aiman Naveed, Huzaifa Ahmad Cheema, Abia Shahid, Mohammad Umer, Hassan Ul Hussain, Mohammad Ebad Ur Rehman, Harpreet Singh, Jonathan S Kurman, Syeda Sahra, Faran Ahmad, Sharjeel Ahmad, Sana Iqbal
{"title":"Favipiravir for the Treatment of Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Aiman Naveed, Huzaifa Ahmad Cheema, Abia Shahid, Mohammad Umer, Hassan Ul Hussain, Mohammad Ebad Ur Rehman, Harpreet Singh, Jonathan S Kurman, Syeda Sahra, Faran Ahmad, Sharjeel Ahmad, Sana Iqbal","doi":"10.1097/MJT.0000000000001688","DOIUrl":"10.1097/MJT.0000000000001688","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e478-e482"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139519028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Abrocitinib in a Patient With Chronic Actinic Dermatitis. 阿布替尼治疗慢性光化性皮炎的疗效。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 Epub Date: 2023-11-16 DOI: 10.1097/MJT.0000000000001671
Xinxing Jin, Jianjun Qiao
{"title":"Effectiveness of Abrocitinib in a Patient With Chronic Actinic Dermatitis.","authors":"Xinxing Jin, Jianjun Qiao","doi":"10.1097/MJT.0000000000001671","DOIUrl":"10.1097/MJT.0000000000001671","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e463-e464"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136395903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
JAK Inhibitors for Treating Steroid-Dependent IgA Vasculitis. 治疗类固醇依赖性 IgA 血管炎的 JAK 抑制剂
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 Epub Date: 2024-03-20 DOI: 10.1097/MJT.0000000000001683
Qingmiao Sun, Juan Bai, Su Wang, Hong Fang, Jianjun Qiao
{"title":"JAK Inhibitors for Treating Steroid-Dependent IgA Vasculitis.","authors":"Qingmiao Sun, Juan Bai, Su Wang, Hong Fang, Jianjun Qiao","doi":"10.1097/MJT.0000000000001683","DOIUrl":"10.1097/MJT.0000000000001683","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e476-e477"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140206244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of Adverse Events Using Flumazenil in Patients With Iatrogenic Benzodiazepine Delirium: A Retrospective Study. 使用氟马西尼治疗苯二氮卓类药物所致谵妄患者的不良事件发生率：回顾性研究。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 DOI: 10.1097/MJT.0000000000001686
Michelle A Hieger, Philip W Moore, Kevin F Maskell
{"title":"Incidence of Adverse Events Using Flumazenil in Patients With Iatrogenic Benzodiazepine Delirium: A Retrospective Study.","authors":"Michelle A Hieger, Philip W Moore, Kevin F Maskell","doi":"10.1097/MJT.0000000000001686","DOIUrl":"10.1097/MJT.0000000000001686","url":null,"abstract":"<p><strong>Background: </strong>Flumazenil is a competitive benzodiazepine (BZD) antagonist most used for treating delirium in BZD overdoses. Since its introduction, many have expressed concerns about its safety secondary to the risk of inducing BZD withdrawal and refractory seizures.</p><p><strong>Study question: </strong>What is the incidence of adverse drug events after the administration of flumazenil in patients with suspected iatrogenic BZD delirium?</p><p><strong>Study design: </strong>This is a retrospective cross-sectional study of patients from a single center from 2010 to 2013. Patients experiencing delirium after receiving BZDs in the hospital were included if they had a bedside toxicology consult and were administered flumazenil. Patients were excluded if they were given BZDs for ethanol withdrawal or if they did not have mental status documentation before and after flumazenil administration. Descriptive statistics were calculated.</p><p><strong>Measures and outcomes: </strong>The primary outcome was the incidence of adverse drug events after flumazenil administration. The secondary outcome was the efficacy of flumazenil determined by the patient's mental status.</p><p><strong>Results: </strong>A total of 501 patient records were reviewed, and 206 patients were included in the final analysis. Of those patients, 172 (83.5%) experienced an objective improvement in their mental status within 1 hour after flumazenil administration. A total of 5 patients experienced adverse events (2.4%), 95% confidence interval (0.78, 5.54). Of these, 3 patients experienced minor agitation or restlessness without pharmacologic intervention. Two patients experienced moderate agitation or restlessness that resolved with haloperidol or physostigmine administration. No patients had a reported seizure, 95% confidence interval (0.0, 1.77).</p><p><strong>Conclusions: </strong>Flumazenil seems to be a safe and effective intervention for the reversal of delirium secondary to iatrogenic BZD administration.</p>","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 4","pages":"e356-e361"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141557853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lactococcus lactis Strain Plasma for the Treatment of Verruca Plana Juvenilis. 用于治疗幼年疣的乳酸乳球菌菌株血浆。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 DOI: 10.1097/MJT.0000000000001718
Yasuhiro Horiuchi
{"title":"Lactococcus lactis Strain Plasma for the Treatment of Verruca Plana Juvenilis.","authors":"Yasuhiro Horiuchi","doi":"10.1097/MJT.0000000000001718","DOIUrl":"10.1097/MJT.0000000000001718","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 4","pages":"e516-e518"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141557854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tofacitinib for the Treatment of Trachyonychia. 治疗软骨病的托法替尼
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 DOI: 10.1097/MJT.0000000000001676
Xinyue Zhong, Taoming Liu, Linwei Wei, Juan Bai, Hong Fang, Jianjun Qiao
{"title":"Tofacitinib for the Treatment of Trachyonychia.","authors":"Xinyue Zhong, Taoming Liu, Linwei Wei, Juan Bai, Hong Fang, Jianjun Qiao","doi":"10.1097/MJT.0000000000001676","DOIUrl":"10.1097/MJT.0000000000001676","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 4","pages":"e468-e470"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141557863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attitudes and Knowledge of Medical Students in South of Israel Toward Medical Cannabis. 以色列南部医科学生对医用大麻的态度和认识。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2024-07-01 DOI: 10.1097/MJT.0000000000001749
Shira Mirzayov, Roni Peleg, Tamar Freud
{"title":"Attitudes and Knowledge of Medical Students in South of Israel Toward Medical Cannabis.","authors":"Shira Mirzayov, Roni Peleg, Tamar Freud","doi":"10.1097/MJT.0000000000001749","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001749","url":null,"abstract":"<p><strong>Background: </strong>Public and medical interest in the use of cannabis has increased in Israel and the world over recent years.</p><p><strong>Study question: </strong>The aim of the study was to assess the attitudes of medical students from the Faculty of Health Sciences of Ben-Gurion University of the Negev on the use of medical cannabis.</p><p><strong>Study design: </strong>This is a cross-sectional study using a self-administered questionnaire completed by medical students from Ben-Gurion University of the Negev, Beer-Sheva, Israel.</p><p><strong>Measures and outcomes: </strong>Attitudes and knowledge toward the use of medical cannabis were evaluated.</p><p><strong>Results: </strong>A total of 243 medical students participated in the study. Of these, 111 (46.1%) were from preclinical years. The mean age was 27.31 ± 3.07, and 138 (57.3%) were female students. Most students (N = 193, 79.4%) agreed to a great degree or to a very great degree that there was a role for cannabis for medical purposes. Most students thought that medical cannabis should be recommended for use by pain specialists (N = 231, 95.1%), by oncologists (N = 208, 85.6%), and by psychiatrists (N = 192, 79%). A little more than half of the participants (N = 127, 52.5%) would agree to be licensed, as future physicians, to prescribe medical cannabis. A logistic regression analysis found that the students strongly agreed with legalization of medical cannabis and students who strongly agreed that medical cannabis should be in the health basket predicted a very strong agreement about its use (OR = 2.623, P ≤ 0.002, and OR = 3.285, P ≤ 0.001, respectively).</p><p><strong>Conclusions: </strong>Most medical students support the use of medical cannabis for medical purposes and are in favor of its legalization. As physicians of the future, it is important to assess the attitudes of medical students on medical cannabis.</p>","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"31 4","pages":"e372-e381"},"PeriodicalIF":2.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141557844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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