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American journal of therapeutics最新文献

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Obinutuzumab in Patients With Active Lupus Nephritis: A Meta-Analysis. Obinutuzumab治疗活动性狼疮性肾炎：荟萃分析
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-27 DOI: 10.1097/MJT.0000000000001988
Allahdad Khan, Shree Rath, Shaista Khadim, Zahid Ullah, Muhammad Junaid, Syed Ahtisham Halim, Asad Ali Ahmed Cheema
{"title":"Obinutuzumab in Patients With Active Lupus Nephritis: A Meta-Analysis.","authors":"Allahdad Khan, Shree Rath, Shaista Khadim, Zahid Ullah, Muhammad Junaid, Syed Ahtisham Halim, Asad Ali Ahmed Cheema","doi":"10.1097/MJT.0000000000001988","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001988","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Methotrexate as a Pain-Relieving Therapy for Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Trials. 甲氨蝶呤缓解骨关节炎疼痛的疗效：随机试验的系统回顾和荟萃分析。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-22 DOI: 10.1097/MJT.0000000000001957
Shree Rath, Osama Ahmad, Mohamed Saad Sayed, Arwa Mohamed Ibrahim, Qasim Mehmood
{"title":"Efficacy of Methotrexate as a Pain-Relieving Therapy for Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Trials.","authors":"Shree Rath, Osama Ahmad, Mohamed Saad Sayed, Arwa Mohamed Ibrahim, Qasim Mehmood","doi":"10.1097/MJT.0000000000001957","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001957","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Flow Nasal Cannula Versus Noninvasive Ventilation in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trial. 慢性阻塞性肺疾病急性加重期患者的高流量鼻插管与无创通气：随机临床试验的系统回顾和荟萃分析
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-22 DOI: 10.1097/MJT.0000000000001985
Allahdad Khan, Sushma Rathi, Hussain Salim, Ali Jawwad Karim, Arisha Akhtar, Kumail Mustafa Ali, Sheema Saadia, Raza Aslam
{"title":"High-Flow Nasal Cannula Versus Noninvasive Ventilation in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trial.","authors":"Allahdad Khan, Sushma Rathi, Hussain Salim, Ali Jawwad Karim, Arisha Akhtar, Kumail Mustafa Ali, Sheema Saadia, Raza Aslam","doi":"10.1097/MJT.0000000000001985","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001985","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Empagliflozin Versus Placebo in Type 2 Diabetes and Cardiovascular Disease: A Systematic Review and Meta-Analysis. 恩格列净与安慰剂在2型糖尿病和心血管疾病中的疗效：一项系统综述和荟萃分析
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-22 DOI: 10.1097/MJT.0000000000001983
Adarsh Raja, Hafsah Alim Ur Rahman, Ali Abdullah, Saad Ashraf, Muhammad Ahmed, Muhammad Ahmed Ali Fahim, Bazil Azeem, Shafin Bin Amin, Muhammad Sohaib Asghar
{"title":"Empagliflozin Versus Placebo in Type 2 Diabetes and Cardiovascular Disease: A Systematic Review and Meta-Analysis.","authors":"Adarsh Raja, Hafsah Alim Ur Rahman, Ali Abdullah, Saad Ashraf, Muhammad Ahmed, Muhammad Ahmed Ali Fahim, Bazil Azeem, Shafin Bin Amin, Muhammad Sohaib Asghar","doi":"10.1097/MJT.0000000000001983","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001983","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is Artificial Intelligence Always for the Benefit of Patients? 人工智能总是为患者造福吗？
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-22 DOI: 10.1097/MJT.0000000000001804
George Koulaouzidis, Lamprini Tsigkriki, Fotis Dimitriadis, Maria Kalaitzoglou, Nikolaos Antoniou, Adam Tsaousidis, Michail Siarkos, Pinelopi Giannakopoulou, Dafni Charisopoulou
{"title":"Is Artificial Intelligence Always for the Benefit of Patients?","authors":"George Koulaouzidis, Lamprini Tsigkriki, Fotis Dimitriadis, Maria Kalaitzoglou, Nikolaos Antoniou, Adam Tsaousidis, Michail Siarkos, Pinelopi Giannakopoulou, Dafni Charisopoulou","doi":"10.1097/MJT.0000000000001804","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001804","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continued Versus Interrupted Oral Anticoagulation During Transcatheter Aortic Valve Replacement in Patients With Atrial Fibrillation: A Meta-Analysis. 心房颤动患者经导管主动脉瓣置换术期间持续口服抗凝与中断口服抗凝：一项荟萃分析
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-21 DOI: 10.1097/MJT.0000000000001979
Hritvik Jain, Nandan Patel, Muhammad Daoud Tariq, Ali Saad Al-Shammari, Rozi Khan, Jyoti Jain, Rahul Patel, Faizan Ahmed, Raheel Ahmed, Thomas Alexander
{"title":"Continued Versus Interrupted Oral Anticoagulation During Transcatheter Aortic Valve Replacement in Patients With Atrial Fibrillation: A Meta-Analysis.","authors":"Hritvik Jain, Nandan Patel, Muhammad Daoud Tariq, Ali Saad Al-Shammari, Rozi Khan, Jyoti Jain, Rahul Patel, Faizan Ahmed, Raheel Ahmed, Thomas Alexander","doi":"10.1097/MJT.0000000000001979","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001979","url":null,"abstract":"<p><strong>Introduction: </strong>A substantial number of patients undergoing transcatheter aortic valve replacement (TAVR) require long-term oral anticoagulants (OAC) owing to comorbidities. This study examined whether continuing oral anticoagulation periprocedurally during TAVR is as safe and effective as interrupting it.</p><p><strong>Methods: </strong>A systematic search of the major databases was performed to identify relevant studies. Effect estimates were calculated using risk ratios (RR) and 95% CIs by pooling the data using the inverse-variance random effects model. Statistical significance was set at P < 0.05.</p><p><strong>Results: </strong>Four studies were included, with 2962 patients undergoing TAVR with continued OAC (n = 1318) and interrupted OAC (n = 1644). The pooled analysis demonstrated that TAVR with continued OAC had comparable risks for all-cause mortality (RR: 0.91; 95% CI, 0.62-1.34; P = 0.64), cardiovascular mortality (RR: 0.89; 95% CI, 0.43-1.84; P = 0.76), stroke (RR: 0.67; 95% CI, 0.42-1.08; P = 0.09), closure device failure (RR: 0.86; 95% CI, 0.47-1.59; P = 0.64), major/life-threatening bleeding (RR: 0.93; 95% CI, 0.74-1.15; P = 0.49), and major vascular complications (RR: 0.97; 95% CI, 0.79-1.20; P = 0.80) compared with TAVR with interrupted OAC.</p><p><strong>Conclusions: </strong>In patients undergoing TAVR, continued OAC showed comparable safety and efficacy with interrupted OAC. These findings demonstrate that continuing OAC in the periprocedural period may be a viable option in patients with atrial fibrillation because of comorbidities requiring anticoagulants.</p>","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Herpes Simplex Infection in Treatment-Refractory Plasma Cell Vulvovaginitis. 单纯疱疹感染治疗难治性浆细胞外阴阴道炎。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-20 DOI: 10.1097/MJT.0000000000001916
SiWen Lu, Gaozhong Ding, YuXin Cheng, Han Li, Lan Sun
{"title":"Herpes Simplex Infection in Treatment-Refractory Plasma Cell Vulvovaginitis.","authors":"SiWen Lu, Gaozhong Ding, YuXin Cheng, Han Li, Lan Sun","doi":"10.1097/MJT.0000000000001916","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001916","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Normobaric Oxygen Therapy Adjunctive to Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials. 常压氧治疗辅助血管内血栓切除术治疗急性缺血性卒中：一项随机对照试验的meta分析。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-20 DOI: 10.1097/MJT.0000000000001954
Umama Alam, Muhammad Abdullah Ali, Sufyan Shahid, Fatima Sajjad, Furqan Ahmad Sethi, Fazia Khattak, Abdullah Afridi
{"title":"Normobaric Oxygen Therapy Adjunctive to Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials.","authors":"Umama Alam, Muhammad Abdullah Ali, Sufyan Shahid, Fatima Sajjad, Furqan Ahmad Sethi, Fazia Khattak, Abdullah Afridi","doi":"10.1097/MJT.0000000000001954","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001954","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nelonemdaz as a Neuroprotective Agent in Acute Ischemic Stroke: A Meta-analysis of RODIN and SONIC Trials. Nelonemdaz作为急性缺血性卒中的神经保护剂：RODIN和SONIC试验的荟萃分析。
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-20 DOI: 10.1097/MJT.0000000000001969
Muhammad Abdullah Ali, Fatima Sajjad, Sufyan Shahid, Umama Alam, Fazia Khattak, Zaryab Bacha, Abdullah Afridi, Asad Iqbal
{"title":"Nelonemdaz as a Neuroprotective Agent in Acute Ischemic Stroke: A Meta-analysis of RODIN and SONIC Trials.","authors":"Muhammad Abdullah Ali, Fatima Sajjad, Sufyan Shahid, Umama Alam, Fazia Khattak, Zaryab Bacha, Abdullah Afridi, Asad Iqbal","doi":"10.1097/MJT.0000000000001969","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001969","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluid Restriction vs Normal Fluids in Infants With Hypoxic-Ischemic Encephalopathy: A Systematic Review and Meta-analysis. 婴儿缺氧缺血性脑病的液体限制与正常液体：系统回顾和荟萃分析
IF 2.9 4区 医学
American journal of therapeutics Pub Date : 2025-05-16 DOI: 10.1097/MJT.0000000000001960
Shree Rath, Allahdad Khan, Shaista Khadim, Umama Alam, Muhammad Junaid, Hamza Khan, Fareeda Brohi
{"title":"Fluid Restriction vs Normal Fluids in Infants With Hypoxic-Ischemic Encephalopathy: A Systematic Review and Meta-analysis.","authors":"Shree Rath, Allahdad Khan, Shaista Khadim, Umama Alam, Muhammad Junaid, Hamza Khan, Fareeda Brohi","doi":"10.1097/MJT.0000000000001960","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001960","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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