发布求助
文献互助 智能选刊 最新文献

American journal of therapeutics最新文献

筛选
英文 中文
Efficacy and Safety of Abrocitinib in the Treatment of Prurigo Nodularis: A Real-World Study. 阿布替尼治疗结节性痒疹的有效性和安全性：一项现实世界研究。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 Epub Date: 2026-08-27 DOI: 10.1097/MJT.0000000000002207
Yu-Ting Gan, Xun Zhou
{"title":"Efficacy and Safety of Abrocitinib in the Treatment of Prurigo Nodularis: A Real-World Study.","authors":"Yu-Ting Gan, Xun Zhou","doi":"10.1097/MJT.0000000000002207","DOIUrl":"10.1097/MJT.0000000000002207","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e463-e464"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148823944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Risk Recognition to Risk Mitigation: Time for Pharmacist-Led Management of DOAC-NSAID Interactions. 从风险识别到风险缓解：药剂师主导的DOAC-NSAID相互作用管理的时间。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 DOI: 10.1097/MJT.0000000000002199
Tangxiaoman Wang, Xinyu Tang
{"title":"From Risk Recognition to Risk Mitigation: Time for Pharmacist-Led Management of DOAC-NSAID Interactions.","authors":"Tangxiaoman Wang, Xinyu Tang","doi":"10.1097/MJT.0000000000002199","DOIUrl":"https://doi.org/10.1097/MJT.0000000000002199","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 5","pages":"e461-e462"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disitamab Vedotin-Associated Psoriasis. 维多汀相关银屑病。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 DOI: 10.1097/MJT.0000000000001936
Xiao Qiu, Sheng Li, Yu-Ge Zhang, Hong-Yan Tan, Lv-Yao Wang, Hua Liu, Bing-Jun Shi
{"title":"Disitamab Vedotin-Associated Psoriasis.","authors":"Xiao Qiu, Sheng Li, Yu-Ge Zhang, Hong-Yan Tan, Lv-Yao Wang, Hua Liu, Bing-Jun Shi","doi":"10.1097/MJT.0000000000001936","DOIUrl":"https://doi.org/10.1097/MJT.0000000000001936","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 5","pages":"e405"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Management of SSRI-Related Sexual Dysfunction. ssri相关性功能障碍的治疗。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 DOI: 10.1097/MJT.0000000000002214
Ahmed Naguy, Elham Alduaij
{"title":"The Management of SSRI-Related Sexual Dysfunction.","authors":"Ahmed Naguy, Elham Alduaij","doi":"10.1097/MJT.0000000000002214","DOIUrl":"https://doi.org/10.1097/MJT.0000000000002214","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148862961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SGLT-2 Inhibitors and Mortality in Cardiac Amyloidosis: A Systematic Review and Meta-Analysis. 心脏淀粉样变性患者的SGLT-2抑制剂和死亡率：一项系统综述和荟萃分析。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 DOI: 10.1097/MJT.0000000000002141
Daniel Paulino-González, Miguel A Pardiño-Vega, Andrea C Beltran-De la Fuente, Crystal A Ek-Góngora, Daniel L Samaniego, Daniel A Navarro-Martinez
{"title":"SGLT-2 Inhibitors and Mortality in Cardiac Amyloidosis: A Systematic Review and Meta-Analysis.","authors":"Daniel Paulino-González, Miguel A Pardiño-Vega, Andrea C Beltran-De la Fuente, Crystal A Ek-Góngora, Daniel L Samaniego, Daniel A Navarro-Martinez","doi":"10.1097/MJT.0000000000002141","DOIUrl":"https://doi.org/10.1097/MJT.0000000000002141","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 5","pages":"e410-e413"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous Immunoglobulin Versus Plasma Exchange for Guillain-Barré Syndrome: An Updated Meta-Analysis of Randomized Trials. 静脉注射免疫球蛋白与血浆置换治疗格林-巴勒综合征：一项随机试验的最新荟萃分析
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 Epub Date: 2026-08-03 DOI: 10.1097/MJT.0000000000002189
Tallal M Hashmi, Zain Tariq, Gautham Srinivasan, Ahmed Abbas
{"title":"Intravenous Immunoglobulin Versus Plasma Exchange for Guillain-Barré Syndrome: An Updated Meta-Analysis of Randomized Trials.","authors":"Tallal M Hashmi, Zain Tariq, Gautham Srinivasan, Ahmed Abbas","doi":"10.1097/MJT.0000000000002189","DOIUrl":"https://doi.org/10.1097/MJT.0000000000002189","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 5","pages":"e453-e455"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Sodium-Glucose Cotransporter-2 Inhibitors With Fournier Gangrene: A Disproportionality Analysis Using the Japanese Adverse Drug Event Report Database. 钠-葡萄糖共转运蛋白-2抑制剂与富尼耶坏疽的关联：使用日本不良药物事件报告数据库的歧化分析。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 DOI: 10.1097/MJT.0000000000002144
Xinjuan Sun, Lei Wang, Gai Li, Haitao Zhang, Liyi Li, Guangyuan Xiang, Tianyuan Wang, Leilei Dong, Jin'an Chen, Aiping Wang
{"title":"Association of Sodium-Glucose Cotransporter-2 Inhibitors With Fournier Gangrene: A Disproportionality Analysis Using the Japanese Adverse Drug Event Report Database.","authors":"Xinjuan Sun, Lei Wang, Gai Li, Haitao Zhang, Liyi Li, Guangyuan Xiang, Tianyuan Wang, Leilei Dong, Jin'an Chen, Aiping Wang","doi":"10.1097/MJT.0000000000002144","DOIUrl":"10.1097/MJT.0000000000002144","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the association between sodium-glucose cotransporter-2 (SGLT2) inhibitors and Fournier gangrene (FG), analyzing additional risk factors using pharmacovigilance data.</p><p><strong>Data sources: </strong>Data were extracted from the Japanese Adverse Drug Event Reporting (JADER) database (April 2014-August 2024), encompassing 914,713 adverse event reports, including 5770 involving SGLT2 inhibitors.</p><p><strong>Main findings and limitations: </strong>Among 40 identified FG cases (0.69% of SGLT2 reports), empagliflozin showed the strongest association (reporting odds ratio = 78.62) and canagliflozin the weakest. Male patients demonstrated significantly higher FG risk than female patients (P = 0.004), particularly with tofogliflozin. No significant correlation existed between obesity and FG occurrence. Onset timing varied widely (12-1515 days). Limitations include potential data incompleteness inherent to spontaneous reporting systems, limited sample size, and inability to establish definitive causality.</p><p><strong>Conclusions: </strong>All 5 SGLT2 inhibitors were associated with FG, with empagliflozin carrying the highest risk. Male patients exhibited elevated susceptibility. Continuous monitoring throughout treatment is essential. Further clinical trials are warranted to clarify causal relationships.</p>","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 5","pages":"e414-e417"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and Safety of Baricitinib in Refractory Juvenile Dermatomyositis: A Retrospective Study. 巴西替尼治疗难治性青少年皮肌炎的疗效和安全性：回顾性研究。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 Epub Date: 2026-08-28 DOI: 10.1097/MJT.0000000000002143
Shi Yan, Yu-Ting Gan, Qin Hu, Qi He, Bin Zhang, Qing-Chun Diao
{"title":"Efficacy and Safety of Baricitinib in Refractory Juvenile Dermatomyositis: A Retrospective Study.","authors":"Shi Yan, Yu-Ting Gan, Qin Hu, Qi He, Bin Zhang, Qing-Chun Diao","doi":"10.1097/MJT.0000000000002143","DOIUrl":"10.1097/MJT.0000000000002143","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e418-e420"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Steroid-free Clearance of Refractory Leukocytoclastic Vasculitis With Abrocitinib. 阿布替尼快速无类固醇清除难治性白细胞破碎性血管炎。
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 DOI: 10.1097/MJT.0000000000002057
Yu-Ting Gan, Shi Yan, Yi Liu, Feng-Lin Chen
{"title":"Rapid Steroid-free Clearance of Refractory Leukocytoclastic Vasculitis With Abrocitinib.","authors":"Yu-Ting Gan, Shi Yan, Yi Liu, Feng-Lin Chen","doi":"10.1097/MJT.0000000000002057","DOIUrl":"https://doi.org/10.1097/MJT.0000000000002057","url":null,"abstract":"","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":"33 5","pages":"e447-e448"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148910662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the Safety and Efficacy of Outpatient Parenteral Antibiotic Therapy Versus Hospital-Based Antibiotic Therapy in Patients with Infective Endocarditis: A Systematic Review and Meta-Analysis. 比较门诊肠外抗生素治疗与医院抗生素治疗对感染性心内膜炎患者的安全性和有效性：一项系统回顾和荟萃分析
IF 3.5 4区 医学
American journal of therapeutics Pub Date : 2026-09-01 Epub Date: 2026-08-28 DOI: 10.1097/MJT.0000000000002213
Mohanad A Alkuwaiti, Faisal A Al-Harbi, Feras A Alkuwaiti, Ahmed K Alsaif, Hamza Ashraf
{"title":"Comparing the Safety and Efficacy of Outpatient Parenteral Antibiotic Therapy Versus Hospital-Based Antibiotic Therapy in Patients with Infective Endocarditis: A Systematic Review and Meta-Analysis.","authors":"Mohanad A Alkuwaiti, Faisal A Al-Harbi, Feras A Alkuwaiti, Ahmed K Alsaif, Hamza Ashraf","doi":"10.1097/MJT.0000000000002213","DOIUrl":"10.1097/MJT.0000000000002213","url":null,"abstract":"<p><strong>Introduction: </strong>Infective endocarditis (IE) requires 4 to 6 weeks of intravenous antibiotics. Outpatient parenteral antibiotic therapy (OPAT) is increasingly used and guideline endorsed, but IE-specific comparative evidence is limited, as prior meta-analyses pooled single-arm data without an inpatient comparator. We compared the safety and efficacy of OPAT versus continued hospital-based antibiotic therapy.</p><p><strong>Methods: </strong>This systematic review and meta-analysis followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020. PubMed/MEDLINE, Embase, Cochrane CENTRAL, and Web of Science were searched to 18 April 2026 for comparative studies of adults with IE. Two reviewers screened using Rayyan and extracted data, and risk of bias was assessed with Risk Of Bias In Non-randomized Studies of Interventions. Random-effects meta-analyses (DerSimonian-Laird) produced risk ratios with 95% confidence intervals (CIs) (RevMan 5.4).</p><p><strong>Results: </strong>Five comparative studies (3497 adults) were included. OPAT was associated with lower all-cause mortality (risk ratio [RR]: 0.40, 95% CI: 0.18-0.90; I 2 = 87%, P = 0.03) and with lower acute kidney failure (RR: 0.71, 95% CI: 0.59-0.86, P = 0.0004). No significant differences were seen for readmission (RR: 1.09), relapse (0.73), valve replacement (1.15), arrhythmia, sepsis, stroke, embolic complications, or heart failure.</p><p><strong>Conclusions: </strong>In appropriately selected, stabilized patients, OPAT was associated with lower all-cause mortality and acute kidney failure, with no significant differences in major other adverse events. Protocol: CRD420261410723 .</p>","PeriodicalId":7760,"journal":{"name":"American journal of therapeutics","volume":" ","pages":"e384-e394"},"PeriodicalIF":3.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148838999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书