{"title":"[22nd annual meeting of the German Work Committee for Histocompatibility Testing. Hamburg, 4-6 October 1990].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 6","pages":"326-50"},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Enteral feeding in oncology].","authors":"G Richter, J Dehnert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nutrition therapy is accepted to represent an important part of therapeutic strategy in cancer patients. In correlation to general clinical state, nutritional condition and anti-cancer therapy, nutrition has to be planned according to a stepwise concept. Under certain circumstances, enteral tube feeding is indicated. This procedure is affected by tumor lesions, digestion, resorption and tumor related metabolic disorders, and side effects of particulate anti-cancer therapy. In tumor patients, elemental (chemically defined) diets are predominant. Polymeric diets, however, occasionally represent another possible nutritional tool.</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 6","pages":"291-9"},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12872801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W Druml, S Zadravec, H Kerbl, G Grimm, B Schneeweiss
{"title":"[Administration of a new fat emulsion in intensive care].","authors":"W Druml, S Zadravec, H Kerbl, G Grimm, B Schneeweiss","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new lipid emulsion for parenteral nutrition, Elolipid, was evaluated for in vitro stability as a component of an all-in-one nutrition solution and, in an open prospective investigation, for clinical tolerance and utilisation in intensive care patients with a broad spectrum of underlying diseases and organ dysfunctions. In vitro stability was determined by photon correlation spectroscopy (mean particle diameter) and Coulter Counter cell sizing (particle size distribution) after 0, 24, 48, 96 h of storage at temperatures of 4 degrees C and 25 degrees C. Mean particle diameter of 330 nm was not altered at any storage time or temperature. The portion of particles with an diameter of greater than 1,000 nm increased mildly during storage of 96 h at room temperature. 31 critically ill patients (mean age 55 +/- 3 years) entered the clinical study: 23 subjects were on artificial ventilation, 15 acquired septicemia, 9 renal insufficiency, and 7 acute or chronic hepatic failure. Fat was given as a component of an all-in-one solution at a rate of 1 g/kg b.w./day for a mean duration of 10 +/- 2 days. Plasma triglycerice concentrations rose mildly between days 3 and 5 only, but in none of the patients the infusion had to be stopped. Lipid-related disturbances of glucose or electrolyte metabolism, hepatic function, cholestasis, induction of disseminated coagulation, impairment of pulmonary gas exchange or renal function were not seen. 7 of 31 patients (22%) died. Side effects of complications attributable to the fat infusion could not be identified. It is concluded that the new lipid emulsion Elolipid is stable as a component of an all-in-one parenteral nutrition solution, is free of side effects and is well-tolerated and utilized even in critically ill patients with multiple organ dysfunctions.</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 6","pages":"306-12"},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13283193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Wittkopf, A Grundmann, W Sibrowski, B von Eisenhart-Rothe, P Kühnl
{"title":"[Analysis of irregular antibodies at the department of transfusion medicine of the Hamburg-Eppendorf University Hospital 1984-1988].","authors":"D Wittkopf, A Grundmann, W Sibrowski, B von Eisenhart-Rothe, P Kühnl","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the University Hospital of Hamburg-Eppendorf (UKE) we performed approximately 80,000 screening tests for irregular RBC antibodies in the years 1984-1988. Among 1,815 (2.27%) positive tests, Rhesus and concomitant antibodies occurred in 0.77% (615/80,000), other clinically important antibodies in 0.37% (293 cases). We found significantly less Rh antibodies than in the previous period of the mid seventies (Rh prophylaxis, completely Rh-compatible transfusions).</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 5","pages":"280-2"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13281251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[German Study Group for Artificial Nutrition. Recommendations for administration of trace elements in parenteral feeding of adults].","authors":"K H Bässler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 5","pages":"283"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13281252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Jung, J Koscielny, C Mrowietz, S Wolf, H Kiesewetter, E Wenzel
{"title":"[Effect of hemodilution on systemic and capillary hematocrit].","authors":"F Jung, J Koscielny, C Mrowietz, S Wolf, H Kiesewetter, E Wenzel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a cross-over study including 10 clinically healthy male volunteers, the hematocrit in the macro- and microcirculation was investigated prior to and 1 h, 3 h, 6 h and 24 h after iso- or (3 months later) hypervolemic hemodilution using 500 ml hydroxyethyl starch. The dilution effect observed after isovolemic hemodilution is more pronounced than after hypervolemic hemodilution. While isovolaemic hemodilution with 500 ml medium molecular weight hydroxyethyl starch leads to a reduction in the systemic hematocrit by 8.5% by volume, the capillary hematocrit at the time of the most marked dilution (1 h after hemodilution) decreases by only 1.3 hematocrit points in the cutaneous capillaries. After hypervolemic hemodilution, the systemic hematocrit decreases significantly by maximally 5.4% by volume, while the capillary hematocrit does not change significantly.</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 5","pages":"268-75"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12869309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F X Lackner, W Graninger, W Ilias, S Panzer, E Schulz
{"title":"[Preoperative autologous blood donation, effect of hydroxyethyl starch on the reticuloendothelial system and opsonins].","authors":"F X Lackner, W Graninger, W Ilias, S Panzer, E Schulz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of 6% low molecular weight (LMW) HES (MW 270,000) on reticuloendothelial function was studied in 9 male patients, median of age 50 years, who were scheduled for vascular surgery. An erythrocyte clearance test (Anti Rh) labeled with 99 mTc, evaluating primarily the splenic section of the RES, showed a considerable variation (37-87%) prior to hemodilution. 24 hours after replacement of 15 ml/kg body weight of blood, there was no significant change of the clearance rate, a follow up weeks later approached the base line values. Plasma opsonins like fibronectin, complement fraction 3, complement fraction 4 and immunoglobulin G showed a proportional decrease following hemodilution, and after 24 hours approached control levels. Changes at this time seemed to be independent from the course of the hematocrit. It is concluded that LMW HES does not adversely influence the spleen dependent phagocytic capacity of the RES system.</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 5","pages":"276-9"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12869310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antioxidant status after surgical stress].","authors":"U Kreinhoff, I Elmadfa, F Salomon, B Weidler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Trauma and anaesthetics are responsible for local and general change in the organism. The characteristic changes in metabolism are caused by hormones. In addition, the increased glycogenolysis, gluconeogenesis, proteolysis and lipolysis are characteristic of this catabolic metabolism. Three groups (injured patients, patients with pulmonary disease, multiple trauma patients) showed an elevated lipid peroxidation as indicated by increased formation of TBA-reactive substances in the post-trauma or after surgery phase. The production of free radicals is supported by several stress factors. In this connection, the state of metabolism of the patients, several anaesthetics and the artificial respiration is very important. Enzymatic protecting systems (SOD, GSH-Px, Catalase) react to oxidative stress by positive adaptation. The non-enzymatic antioxidative systems (tocopherol, ascorbic acid, selen) are diminished, indicating an increased requirement.</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 5","pages":"261-7"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13440230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comparative studies of administration of xylitol or glucose in parenteral infusion of amino acids in critical care patients].","authors":"V Fässle, F W Ahnefeld, A Grünert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a prospective, randomized study, two different concepts of carbohydrate application in the postoperative state were investigated and statistically analyzed in 20 intensive care patients in each group. Aim of the study was to evaluate influences of glucose or xylitol infusions in critically ill patients. Under the strict control of prerequisites for the application of parenteral nutrition in general and the application of specific substrates specifically, the study is based on the hypothesis that adverse reactions of the substrates like hyperglycemia should not occur. As a main result of the study, statistical significances of differences between the two groups could not be substantiated. The only difference between the two groups of severely ill patients with ventilation and hemodynamic support was an instability in glucose concentrations in blood under the application of glucose. Some patients in that group showed an increase in glucose concentration, which made insulin therapy necessary. We conclude that glucose is also applicable under the marked hormonally fixed conditions of postoperative metabolism if a narrow control of glucose is performed with an interruption of glucose application when concentrations increase. Also, on the basis of our data, xylitol showed a higher degree of security because under application of this substrate changes of glucose did not occur. In all cases where physiological conditions are achieved, glucose is the first choice of carbohydrates. In all those cases where the possibility exists that behind a normalized glucose concentration alterations of metabolism may be hidden, the application of xylitol offers the possibility to avoid imbalances and substrate load.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"17 5","pages":"251-6"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13281249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}