Cell differentiation and development : the official journal of the International Society of Developmental Biologists最新文献_第9页

Contents of volume 30 第30卷内容

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-06-01 DOI: 10.1016/0922-3371(90)90142-J

引用次数: 0

Positional cues and differential gene expression in somatic embryos of higher plants 高等植物体细胞胚胎的位置线索与差异基因表达

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-06-01 DOI: 10.1016/S0922-3371(90)80001-2

Richard H. Racusen, F. Mark Schiavone

{"title":"Positional cues and differential gene expression in somatic embryos of higher plants","authors":"Richard H. Racusen, F. Mark Schiavone","doi":"10.1016/S0922-3371(90)80001-2","DOIUrl":"10.1016/S0922-3371(90)80001-2","url":null,"abstract":"<div><p>Much of the organization of higher vascular plants is determined during the formation of the embryo. In addition to the zygotic embryo which results from sexual fertilization in the ovule, many plants are capable of producing embryos from somatic cells. Of particular interest to plant developmental biologists is the phenomenon of somatic embryogenesis in cultures of the domesticated carrot which, because of its tractable nature in experimental manipulations, is presently regarded as a suitable model for studying pattern formation in plants. This short review considers the state of our knowledge concerning the origin and perception of positional information in plant embryos, and the temporal and spatial expression of genes. The available data provide a number of promising leads for cell-cell interactions in embryos, and there are some clear indications that the spatial distribution of certain gene products is correlated with changes in morphology. However, there is, as yet, insufficient evidence with which to forge a link between positional cues and the expression of genes which influence developmental transitions in embryos.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 3","pages":"Pages 159-169"},"PeriodicalIF":0.0,"publicationDate":"1990-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0922-3371(90)80001-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13359454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 28

Extracellular matrix: an immunological and biochemical (CAT and TOH activity) survey of in vitro differentiation of isolated amphibian neuroblasts 细胞外基质:分离的两栖类神经母细胞体外分化的免疫学和生化(CAT和TOH活性)调查

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-06-01 DOI: 10.1016/0922-3371(90)90141-I

S. Huang, J.P. Saint-Jeannet, P. Kan, A.M. Duprat

{"title":"Extracellular matrix: an immunological and biochemical (CAT and TOH activity) survey of in vitro differentiation of isolated amphibian neuroblasts","authors":"S. Huang, J.P. Saint-Jeannet, P. Kan, A.M. Duprat","doi":"10.1016/0922-3371(90)90141-I","DOIUrl":"10.1016/0922-3371(90)90141-I","url":null,"abstract":"<div><p>After neural induction certain cells in the neuroepithelium immediately acquire the property to express certain neural phenotypes (Duprat et al., 1984, 1987). However, the activity of almost all the specific enzymes involved in the biosynthesis of neurotransmitters is considerably higher when neurectodermal cells are cultured with chordamesodermal cells than when they are cultured alone. The stimulating effects of chordamesoderm do not appear to be due to diffusible factors (Duprat et al., 1985b). The present study was designed to investigate the role of extracellular matrix components in neuronal cell differentiation. We showed that the extracellular matrix cannot replace chordamesoderm in stimulating the biochemical differentiation of neuroblasts, although fibronectin and especially laminin stimulate morphological differentiation. We suggest that interaction between neuronal and non-neuronal cells plays an important part in functional biochemical differentiation, whereas the molecules of extracellular matrix are important for morphological differentiation.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 3","pages":"Pages 219-233"},"PeriodicalIF":0.0,"publicationDate":"1990-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90141-I","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13133600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Chick oviduct differentiation. The effect of estrogen and progesterone on the expression of progesterone receptor 鸡输卵管分化。雌激素和孕激素对孕激素受体表达的影响

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-06-01 DOI: 10.1016/0922-3371(90)90140-R

Timo K. Joensuu

{"title":"Chick oviduct differentiation. The effect of estrogen and progesterone on the expression of progesterone receptor","authors":"Timo K. Joensuu","doi":"10.1016/0922-3371(90)90140-R","DOIUrl":"10.1016/0922-3371(90)90140-R","url":null,"abstract":"<div><p>Progesterone receptor (PR) is a marker of estrogen action. Its cellular appearance during estrogen (20 mg/kg i.m.)-induced differentiation of the immature chick oviduct was therefore studied by immunohistochemistry. PR was located in the epithelial, mesothelial, submucosal stromal and smooth muscle cells. Progesterone (20 mg/kg i.m.) caused an obvious decrease in PR immunoreactivity without inducing synthesis of progesterone-dependent avidin. Thus mere receptor occupation by ligand is not sufficient for this induction. This paper reports that the expression of PR in the mucosal stromal cell differs from that in other cell types. In the mucosal stromal cell PR was inducible, i.e., not shown without the action of estrogen. The formation of tubular glands did not commence before mucosal stromal cells expressed PR. It would seem that the mucosal stromal cells have a crucial role in mediating epithelial differentiation. The onset of differentiation was preceded by vascularization and invasion of mononuclear cells in the submucosa. It was conspicuous that the smooth muscle cells of arteries also contained PR.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 3","pages":"Pages 207-218"},"PeriodicalIF":0.0,"publicationDate":"1990-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90140-R","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13360646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Identification of specific glomerular cell types in culture by use of lectin and antibody binding 利用凝集素和抗体结合鉴定培养中的特定肾小球细胞类型

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-06-01 DOI: 10.1016/0922-3371(90)90138-M

H. Holthöfer, S. DeCandido, D. Schlondorff

{"title":"Identification of specific glomerular cell types in culture by use of lectin and antibody binding","authors":"H. Holthöfer, S. DeCandido, D. Schlondorff","doi":"10.1016/0922-3371(90)90138-M","DOIUrl":"10.1016/0922-3371(90)90138-M","url":null,"abstract":"<div><p>To characterize the outgrowth of cells from cultured rat glomeruli, we examined the cell morphology in relation to the expression of various antigenic determinants (factor VIII-related antigen, rat Thy 1.1, Heyman nephritogenic antigen, common leucocyte and Ia antigens) and lectin binding patterns. For this purpose, early (3–7 days) to late (4–5 weeks) glomerulus cultures, as well as subcultures of mesangial cells were used. In the early samples, the predominance of small round (type I) cells growing in a cobblestone pattern was noted. These cells failed to express specific binding for any of the antibodies or lectins tested. 5–10% of the outgrowing cells appeared single and morphologically of stellate shape (type II). These cells were reactive for <em>Concanavalia ensiformis</em> (ConA), <em>Triticum vulgaris</em> (WGA) and <em>Ricinus communis</em> (RCA I), and stained for rat Thy 1.1 antigen. Large round, single cells (type III), found mostly at the edges of the outgrowth bound only <em>Bandeiraea simplicifolia</em> (BSI-B4) and FVIII antibodies, a pattern consistent with endothelial cells. A fourth (type IV) cell type, elongated, with cells mostly found in bundles and growing on a layer consisting of other cells, was reactive for ConA, WGA, <em>Limax flavus</em> (LFA) and <em>Maclura pomifera</em> (MPA) lectins. In the late outgrowth (3–5 weeks after explant), the lectin and antibody binding patterns of each cell type remained essentially unchanged. However, considerable changes in the prevalence of the morphologic cell types were noted. Cells that had been subcultured to obtain pure ‘mesangial’ cells, exhibited the same morphology as the type II cells and expressed identical staining patterns with all probes used. The binding of lectins was likewise confirmed by staining frozen sections of rat kidneys.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 3","pages":"Pages 181-194"},"PeriodicalIF":0.0,"publicationDate":"1990-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90138-M","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12863250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Characteristics of embryonic stem cell differentiation: a comparison with two embryonal carcinoma cell lines 胚胎干细胞分化的特点:与两种胚胎癌细胞系的比较

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-06-01 DOI: 10.1016/0922-3371(90)90139-N

C.L. Mummery, A. Feyen, E. Freund, S. Shen

{"title":"Characteristics of embryonic stem cell differentiation: a comparison with two embryonal carcinoma cell lines","authors":"C.L. Mummery, A. Feyen, E. Freund, S. Shen","doi":"10.1016/0922-3371(90)90139-N","DOIUrl":"10.1016/0922-3371(90)90139-N","url":null,"abstract":"<div><p>Embryonic stem (ES) cells isolated from late blastocysts can now be maintained in culture in an undifferentiated state provided they are grown in the presence of a specific differentiation inhibitor, known variously as leukaemia inhibiting factor (LIF) or differentiation inhibiting activity (DIA), found at high concentrations in medium conditioned by Buffalo rat liver (BRL) cells. ES cells acquired a differentiated phenotype in monolayer, either when in the absence of LIF/DIA or in the presence of retinoic acid (RA). We have now characterized this bipotential differentiation of ES cells in terms of a series of extracellular matrix and cell surface proteins as well as cytokeratin expression, and compared it with the changes observed during the differentiation of two embryonal carcinoma (EC) cell lines, P19 and F9. ES cells exposed to RA in the presence of LIF/DIA largely resembled F9 EC + RA after 5 days, while ES cells deprived of LIF/DIA formed a culture with mixed phenotype resembling P19 EC + RA. This study therefore establishes the predominantly parietal endoderm-like phenotype of cells derived from ES by RA induction, and suggests that a mixed population of endoderm- and ill-defined mesoderm-like cells are formed after removal of specific inhibitor(s) of differentiation.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 3","pages":"Pages 195-206"},"PeriodicalIF":0.0,"publicationDate":"1990-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90139-N","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12863251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 111

Subject index volume 30 主题索引第30卷

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-06-01 DOI: 10.1016/0922-3371(90)90144-L

引用次数: 0

Experimental analysis of the role of ECM in the patterning of the distal tendons of the developing limb bud ECM在发育中的肢体芽远端肌腱形态中的作用的实验分析

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-05-01 DOI: 10.1016/0922-3371(90)90078-B

J.M. Hurle , M.A. Ros , Y. Gañan , D. Macias , M. Critchlow , J.R. Hinchliffe

{"title":"Experimental analysis of the role of ECM in the patterning of the distal tendons of the developing limb bud","authors":"J.M. Hurle , M.A. Ros , Y. Gañan , D. Macias , M. Critchlow , J.R. Hinchliffe","doi":"10.1016/0922-3371(90)90078-B","DOIUrl":"10.1016/0922-3371(90)90078-B","url":null,"abstract":"<div><p>We have shown previously that from stage 27 the distal growing region of the limb exhibits a tenascin-rich sheet of extracellular matrix termed the “mesenchyme lamina” (ML), which runs from the ectodermal basement membrane in a proximal direction until it contacts the distal tip of the muscle blocks. This study reports experimental evidence that the mesenchyme lamina is a pretendinous structure that controls the spatial organization of the flexor and extensor tendons of the distal part of the chick leg. Two sets of experiments were designed to alter the ML position and examine subsequent tendon pattern formation. In a first series of experiments limbs with digits lacking phalangeal elements were induced by AER removal at stages 26 and 27. This procedure induced an abnormal arrangement of the ML around the distal tip of each terminal phalange of the truncated digit, which was followed by the development of a precisely similar pattern of abnormal extensor and flexor tendons. In the second set of experiments, an extradigit was induced to form in the interdigital mesenchyme through surgical removal of the marginal ectoderm of the third interdigit of stage 29 leg buds. By day 4 post-operation, a chondrogenic extradigit had formed, together with a ML that ran from the cartilage to the normal ventral flexor and dorsal extensor tendons. By day 6 post-operation, the experimentally induced ML had transformed into a tendinous structure connecting with the adjacent normal tendon. Both experiments show that the position of the ML defines the position of subsequent tendon development, thus supporting its role as a pretendinous structure which might be responsible for the alignment of the pretendinous condensing cells.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 2","pages":"Pages 97-108"},"PeriodicalIF":0.0,"publicationDate":"1990-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90078-B","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13534945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 59

Established mouse liver cell lines as a model system for studying epithelio-mesenchymal interactions in morphogenesis 建立小鼠肝细胞系作为研究上皮-间充质相互作用在形态发生中的模型系统

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-05-01 DOI: 10.1016/0922-3371(90)90080-G

Yuichi Kadoya

{"title":"Established mouse liver cell lines as a model system for studying epithelio-mesenchymal interactions in morphogenesis","authors":"Yuichi Kadoya","doi":"10.1016/0922-3371(90)90080-G","DOIUrl":"10.1016/0922-3371(90)90080-G","url":null,"abstract":"<div><p>Four cell lines were established from both fetal and adult livers of mice (ddY strain) by colony isolation methods, and these were characterized by morphological, immunological and biochemical examination. An epithelial cell line from a fetus (eE1-10) was identified to be derived from the biliary tract epithelium. Another epithelial cell line from an adult (aE3) reconstructed bile canaliculi-like structures in aggregates and secreted several serum proteins, indicating that it was derived from the hepatic parenchyma. The other two lines (eF1 and aF1) are fibroblastic in morphology. These were derived from fetal and adult livers, respectively. Both eE1-10 and the fetal fibroblastic cell line (eF1) are hypotetraploid, whereas both aE3 and the adult fibroblastic cell line (aF1) are hypodiploid. All four cell lines showed both contact inhibition and anchorage dependency of growth. Luminal structures with basal laminar, similar to bile ducts, were reconstituted from eE1-10 cells when co-aggregated with aF1 fibroblastic cells. Luminal structures were also formed from eE1-10 cells embedded in collagen gel. These, however, had no basal lamina and there was less development of microvilli than in aggregates mixed with fibroblastic cells. These results indicate that the fibroblastic cells afford favourable conditions for maintenance of the elaborated luminal structure of epithelial cells through production of the basal lamina.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 2","pages":"Pages 117-128"},"PeriodicalIF":0.0,"publicationDate":"1990-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90080-G","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13534943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Neural-tube-derived melanocyte subsets undergo commitment to their distinct lineages in culture 神经管来源的黑素细胞亚群在培养中经历其独特谱系的承诺

Cell differentiation and development : the official journal of the International Society of Developmental Biologists Pub Date : 1990-05-01 DOI: 10.1016/0922-3371(90)90081-7

Raymond E. Boissy , Linda S. Trinkle, James J. Nordlund

{"title":"Neural-tube-derived melanocyte subsets undergo commitment to their distinct lineages in culture","authors":"Raymond E. Boissy , Linda S. Trinkle, James J. Nordlund","doi":"10.1016/0922-3371(90)90081-7","DOIUrl":"10.1016/0922-3371(90)90081-7","url":null,"abstract":"<div><p>Neural-crest-derived melanocytes populate two anatomical sites in the chicken, the epidermis of regenerating feathers and the uveal tract of the eyes. These two anatomical populations of melanocytes differ morphologically and functionally. Morphologically, feather and uveal melanocytes synthesize structurally different pigment granules (melanosomes). Feather melanosomes are rod-shaped, 0.2 × 0.8 μm, whereas uveal melanosomes are larger and more oval, 0.6 × 0.9 μm. Functionally, feather melanocytes continuously synthesize melanosomes during feather regeneration, and transfer these melanosomes to neighboring keratinocytes. Ocular melanocytes, on the other hand, synthesize melanosomes until their cytoplasm becomes congested with melanosomes, at which time the melanocytes become melanogenically dormant and do not transfer granules to neighboring cells. Cultures of melanocytes established from neural tubes of Light Brown Leghorn chick embryos produce two populations of melanocytes containing small (0.45 μm) or larger (0.90 μm) melanosomes which resemble the two types described in situ. Both types of melanocytes emigrate from along the entire length of the neural tube during several embryonic stages. Melanocyte cultures developed from neural tubes of the Recessive White breed of chicken, which has tyrosinase-negative, feather melanocytes and pigmented, functionally normal uveal melanocytes, also develop a mixture of amelanotic and pigmented melanocytes which maintain their respective characteristics even after separation by flow cytometry and reculture. These findings suggest that epidermal and uveal melanocytes are two distinct sub-populations of melanocytes whose commitment to separate lineages can occur in culture in the absence of their respective target tissue environment.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"30 2","pages":"Pages 129-145"},"PeriodicalIF":0.0,"publicationDate":"1990-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90081-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13534944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9