Biomaterials, artificial cells, and artificial organs最新文献_第3页

Bioreactors in medicine. 医学上的生物反应器。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009119628

A S Hoffman

引用次数: 4

Adsorption of bilirubin with polypeptide-coated resins. 多肽包被树脂对胆红素的吸附。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117290

X X Zhu, G R Brown, L E St-Pierre

引用次数: 30

On the hydrodynamic instability of hemoglobin solutions. 血红蛋白溶液的流体动力学不稳定性。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117300

T I Pristoupil, T Marík

引用次数: 3

Morphologic alterations in rat retina after hypervolemic infusion of cross-linked hemoglobin. 大鼠视网膜大容量灌注交联血红蛋白后的形态学改变。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117308

S T Schuschereba, C B Clifford, J A Vargas, D Bunch, P D Bowman

{"title":"Morphologic alterations in rat retina after hypervolemic infusion of cross-linked hemoglobin.","authors":"S T Schuschereba, C B Clifford, J A Vargas, D Bunch, P D Bowman","doi":"10.3109/10731199009117308","DOIUrl":"https://doi.org/10.3109/10731199009117308","url":null,"abstract":"Hypervolemic infusion in rats of bis (3,5-dibromosalicyl) fumarate cross-linked hemoglobin (DBBF-Hb) to 40-60% of blood volume produced histologic lesions in retina which were not observed in rats similarly infused with human serum albumin or lactated Ringer's solution. Rats treated with 40% DBBF-Hb, exhibited intermittent zones of dense retinal pigmented epithelium while 60% DBBF-Hb animals exhibited severe inner retinal edema and retinal pigmented epithelium vacuolization, large focal zones of photoreceptor outer segment disruption and in one animal, subretinal hemorrhage. Light microscopic immunocytochemical evaluation of retinas with antibodies directed to human hemoglobin and albumin, showed the presence of both hemoglobin and albumin in this tissue. Transmission electron microscopy of the lesions demonstrated vacuolated retinal pigmented epithelial cells and large areas of focal photoreceptor outer segment disruption. We conclude that hypervolemic infusion disrupts the blood retinal barrier and that although both DBBF Hb and albumin cross, only hemoglobin produced damage in the retina.","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 2","pages":"299-307"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117308","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13519425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Binding of C1q and DNA to support materials by means of a new coupling procedure. 通过一种新的偶联过程将C1q和DNA结合到支持物质上。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117334

W Schössler, F Hiepe, J Coupek, E Apostoloff

引用次数: 2

Swelling of PHEMA based membranes in ethanol and their nitroglycerin permeabilities. 基于PHEMA的膜在乙醇中的膨胀及其硝酸甘油的渗透性。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117291

R Tekin, M Kiremitçi, A I Serbetçi, E Pişkin

{"title":"Swelling of PHEMA based membranes in ethanol and their nitroglycerin permeabilities.","authors":"R Tekin, M Kiremitçi, A I Serbetçi, E Pişkin","doi":"10.3109/10731199009117291","DOIUrl":"https://doi.org/10.3109/10731199009117291","url":null,"abstract":"The aim of this study is to prepare PHEMA based polymeric membranes for a transdermal delivery system, which includes a skin permeation enhancer (i.e. ethanol) for nitroglycerin. Membranes were prepared by bulk polymerization of HEMA monomer. Polymerization was achieved in the presence of EGDMA, as the cross-linker, and AIBN as the initiator. MMA was used as a comonomer to improve the mechanical properties and to adjust the permeabilities of the resulting membranes. Water was also included in the polymerization mixture to control the matrix structure. Membranes with different chemical and physical structures were prepared. Swelling behaviour of these matrices in ethanol were observed. Nitroglycerin diffusion through swollen membranes (in ethanol) were investigated. It was obtained that the relative amounts of ingredients (i.e., HEMA, MMA, EGDMA and water) in the casting solutions affect both the equilibrium swelling values and the permeabilities. By increasing the water content and by decreasing the amounts of MMA and EGDMA both parameters can be increased. AIBN does not affect these parameters significantly.","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 1","pages":"95-106"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117291","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13265568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

The development of a central register for side effects of biomaterials. 建立生物材料副作用的中央登记系统。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117326

U T Seyfert, G Pindur, C Miyashita, F W Albert, E Wenzel

引用次数: 0

Cell adhesion to the surfaces of polymeric beads. 细胞粘附在聚合物珠的表面。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117327

M Kiremitçi, E Pişkin

{"title":"Cell adhesion to the surfaces of polymeric beads.","authors":"M Kiremitçi, E Pişkin","doi":"10.3109/10731199009117327","DOIUrl":"https://doi.org/10.3109/10731199009117327","url":null,"abstract":"The main goal of this study is to determine the relationship between the surface properties of polymeric materials and fibroblastic cell adhesion. Therefore, two series of polymeric beads, PHEMA and PS, were tested in microcarrier-facilitated cell culture systems. The crosslinked PHEMA beads were prepared by suspension polymerization of HEMA monomer in the presence of various acrylic monomers (i.e. MMA, EGDMA, DMAEMA). The hydrophobic PS beads were used after coated with different alkylamine monomers (i.e. EDA, ALAM, TEA) by plasma polymerization process. The cell culturing studies were performed with BHK cells in stationary culture conditions and the cell adhesion characteristics were determined by the common methods. Attachment of the BHK cells on these microcarriers were satisfactorily modeled by surface saturation type of mathematical expression. The results demonstrated that, there were finite number of sites on the microcarrier surfaces available for adhesion. Number of these sites depends on the surface charge density which was supplied by amine groups and surface wettability. It is possible to achieve desired cell adhesion and also growth, by changing the chemical structure of beads with suitable modification methods.","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 5","pages":"599-603"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117327","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13254708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Rapid adsorption of rheumatoid factor (RF) on suspension of glutaraldehyde-crosslinked immunoglobulin G (IgG)--a method to avoid RF interference. 戊二醛交联免疫球蛋白G (IgG)悬浮液快速吸附类风湿因子(RF)——一种避免RF干扰的方法。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117328

G Kolb

引用次数: 0

Immunosorbents based on uncoated synthetic charcoals: preparation, properties, applications. 基于未包覆合成炭的免疫吸附剂:制备，性能，应用。

Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117336

S V Mikhalovsky, V V Strelko, T A Alekseyeva, S V Komissarenko

引用次数: 5