发布求助
文献互助 智能选刊 最新文献

Biomaterials, artificial cells, and artificial organs最新文献

筛选
英文 中文
Transference of hepatic coma to normal rats from galactosamine treated donors by reverse plasma exchange. 半乳糖胺处理供体肝昏迷向正常大鼠的反向血浆交换转移。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009119621
C J Ryan, M Aslam, J M Courtney
{"title":"Transference of hepatic coma to normal rats from galactosamine treated donors by reverse plasma exchange.","authors":"C J Ryan,&nbsp;M Aslam,&nbsp;J M Courtney","doi":"10.3109/10731199009119621","DOIUrl":"https://doi.org/10.3109/10731199009119621","url":null,"abstract":"<p><p>It was possible by exchange transfusion to induce the same grade of hepatic coma in normal recipients as had occurred in donors which had previously been treated with D(+) galactosamine hydrochloride (HCl). The exchange transfusion was carried out by carotid arterial and jugular venous cannulation in conscious and unrestrained recipient rats. Thus, the coma inducing compounds generated as a consequence of acute hepatic failure, appear to circulate in the plasma for a considerable time after galactosamine-HCl is cleared and these substances are able to affect the nervous system in the presence of an intact and functioning normal liver.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 4","pages":"477-82"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009119621","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13436457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Development of selective adsorbent for free-hemoglobin. 游离血红蛋白选择性吸附剂的研制。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009119620
T Tsuchiya, H Kawanishi, M Sugiyama, F Yoshimoto
{"title":"Development of selective adsorbent for free-hemoglobin.","authors":"T Tsuchiya,&nbsp;H Kawanishi,&nbsp;M Sugiyama,&nbsp;F Yoshimoto","doi":"10.3109/10731199009119620","DOIUrl":"https://doi.org/10.3109/10731199009119620","url":null,"abstract":"<p><p>It is well-known that acute renal failure is often caused by hemolysis. Its possible causes may be free-hemoglobin (F-Hb), stroma freed from destroyed red blood cell, and their combined action. Especially, a great amount of F-Hb is liable to flow out during extracorporeal circulation. The plasma fractionation using a membrane has so far been applied to remove F-Hb (1). The molecular weight of F-Hb of 68,000 which is nearly equal to that of albumin has made it still difficult to separate F-Hb effectively. Recently, we have developed an adsorbent that is capable of selectively removing F-Hb and succeeded in obtaining its high adsorption performance.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 4","pages":"471-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009119620","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13436456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Impairment of the post-anoxic recovery of isolated rat hearts by intravascular hypoxanthine and xanthine. 血管内注射次黄嘌呤和黄嘌呤对离体大鼠心脏缺氧后恢复的损害。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117309
M Tarantola, R Motterlini, M Beretta, E Rovida, M Samaja
{"title":"Impairment of the post-anoxic recovery of isolated rat hearts by intravascular hypoxanthine and xanthine.","authors":"M Tarantola,&nbsp;R Motterlini,&nbsp;M Beretta,&nbsp;E Rovida,&nbsp;M Samaja","doi":"10.3109/10731199009117309","DOIUrl":"https://doi.org/10.3109/10731199009117309","url":null,"abstract":"<p><p>Hypoxanthine is the final product of the catabolism of ATP in the stored red cell. Upon transfusion, this purine may be uptaken by the endothelial cell and oxidized in a post-ischemic or post-anoxic environment with production of oxygen-derived free radicals. We have tested this hypothesis with a isolated perfused rat heart model monitoring the recovery of the heart function from 20 min anoxia in the presence of 0.1 mM hypoxanthine or xanthine. Addition of 0.1 mM guanine minimized the fraction of hypoxanthine to be salvaged. The presence of hypoxanthine in the vascular space impaired the recovery of the end-diastolic pressure, left ventricular developed pressure, contraction rate, and coronary perfusion pressure. We conclude that intravascular hypoxanthine is oxidized by the endothelial cell xanthine oxidase contributing to the post-anoxic reoxygenation injury. Since the injury led by equimolar xanthine was nearly half of that observed for hypoxanthine, this injury appears to be correlated to the stoichiometry of the oxygen-derived free radical generating reaction.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 2","pages":"309-20"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13519426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Viscosity measurements of suspensions of hemoglobin-containing liposomes of varying lipid composition. 不同脂质组成的含血红蛋白脂质体悬浮液粘度测量。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117312
B Jopski, V Pirkl, K H Schmidt
{"title":"Viscosity measurements of suspensions of hemoglobin-containing liposomes of varying lipid composition.","authors":"B Jopski,&nbsp;V Pirkl,&nbsp;K H Schmidt","doi":"10.3109/10731199009117312","DOIUrl":"https://doi.org/10.3109/10731199009117312","url":null,"abstract":"<p><p>The viscosity of suspensions of hemoglobin-containing liposomes (Hb liposomes) and of liposomes without Hb was determined as a function of the shear rate. Liposomes of varying lipid composition were prepared by detergent dialysis. All liposome suspensions showed non-Newtonian viscous behavior, as did erythrocyte suspensions. The viscosity of suspensions of Hb liposomes with a bilayer consisting of egg yolk lecithin and phosphatidylserine was almost identical to erythrocyte suspension viscosity. When cholesterol was included in the lipid component of the Hb liposomes, the dependence of viscosity on the shear rate decreased (flattening of the curve), but overall suspension viscosity became higher than that of erythrocyte suspensions. Evidence is provided for the lipid concentration at which liposomes can be applied intravenously.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 2","pages":"345-58"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117312","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13519429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
New method to quantitate platelets adhered on biomaterials using monoclonal antibodies to human platelet membrane glycoprotein SZ-21. 人血小板膜糖蛋白SZ-21单克隆抗体定量测定粘附在生物材料上血小板的新方法。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01
T F Xi, J C Zhang, W H Tian, C R Wang, X H Lei, H Y Wai, C G Ruan
{"title":"New method to quantitate platelets adhered on biomaterials using monoclonal antibodies to human platelet membrane glycoprotein SZ-21.","authors":"T F Xi,&nbsp;J C Zhang,&nbsp;W H Tian,&nbsp;C R Wang,&nbsp;X H Lei,&nbsp;H Y Wai,&nbsp;C G Ruan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study developed a new technique to quantitate platelets adhered on biomaterials surfaces in vitro, based on a surface phased radioimmunoassay using a monoclonal antibody SZ-21, directed specifically against the membrane glycoprotein complex IIIa of human platelets. In vitro perfusion is performed in system which consists of testing tubes and infusion pump. After 5 minutes perfusion with fresh ACD anticoagulated human whole blood at 2,000s-1 platelets deposition on surface precoated with proteins determined using anti-human platelet antibody (125 I-SZ-21) are 4,173 +/- 932 (Albumin), 59,032 +/- 25,554 (Fibrinogen), and 71,253 +/- 11,484 (Collagen). Meanwhile, platelets adhered on surfaces of four polymers were determined (platelet/mm2): 19,493 +/- 2,050 (Silicone), 48,193 +/- 4,055 (Polytetrafluoroethylene), 50,375 +/- 8,675 (Polyvinyl chloride) and 101,906 +/- 5,916 (Polyethylene). These results were confirmed by SEM. This method is not only applied for evaluating rapidly and reliably blood compatibility of biomaterials in vitro, but will be used at basic study for interaction of blood materials.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 3","pages":"423-35"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13533368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanistic aspects of cellular interactions with artificial dialyzer membrane surfaces. 细胞与人工透析器膜表面相互作用的机理。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117324
T Matsuda, Y Takemoto, T Kishimoto, M Maekawa, T Akutsu
{"title":"Mechanistic aspects of cellular interactions with artificial dialyzer membrane surfaces.","authors":"T Matsuda,&nbsp;Y Takemoto,&nbsp;T Kishimoto,&nbsp;M Maekawa,&nbsp;T Akutsu","doi":"10.3109/10731199009117324","DOIUrl":"https://doi.org/10.3109/10731199009117324","url":null,"abstract":"<p><p>The platelet adhesion on adhesive protein-coated surfaces was significantly reduced by the addition of the synthetic tetrapeptide, RGDS (Arg-Gly-Asp-Ser), which was identified as the common amino acid sequence of adhesive site of adhesive proteins. The inhibitory effect was also observed for leukocyte(WBC) in complement-inactivated serum. No significant effect was observed for WBC in complement-activated serum. These indicate that the RGDS ligand-receptor mechanism operates on adhesive protein-adsorbed surfaces for both cellular systems and that activated complement factor (C3b)-membrane receptor (CR3) interaction operates for WBC as the complement is activated.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 5","pages":"579-84"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117324","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13125112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Hemoglobin in a coacervate system. 凝聚系统中的血红蛋白。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117313
J Ecanow, D Ecanow, B Ecanow
{"title":"Hemoglobin in a coacervate system.","authors":"J Ecanow,&nbsp;D Ecanow,&nbsp;B Ecanow","doi":"10.3109/10731199009117313","DOIUrl":"https://doi.org/10.3109/10731199009117313","url":null,"abstract":"<p><p>Hemoglobin dissolved in a coacervate system shows the properties of a resuscitation fluid. In the coacervate system used, the equilibrium phase was the colloid rich phase. We propose a new definition of the coacervate phase to be that phase in a coacervate system which is most dissimilar to water in its physical chemical properties.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 2","pages":"359-65"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117313","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12859759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Hemodialysis-hemoperfusion in fulminant viral hepatitis. 暴发性病毒性肝炎的血液透析-血液灌流。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009117338
C P Ramos, J S Almario
{"title":"Hemodialysis-hemoperfusion in fulminant viral hepatitis.","authors":"C P Ramos,&nbsp;J S Almario","doi":"10.3109/10731199009117338","DOIUrl":"https://doi.org/10.3109/10731199009117338","url":null,"abstract":"<p><p>It is theorized that charcoal hemoperfusion and hemodialysis with a highly permeable membrane should be synergistic in the management of fulminant hepatic failure. Previous studies have shown marked differences between these two treatments in their effects in the various biochemical abnormalities of this serious clinical problem. Survival rates in patients treated with charcoal hemoperfusion approximate the rates in those treated with hemodialysis with a highly permeable membrane but are only slightly better than in untreated cases. The excellent recovery of two patients with fulminant viral hepatitis in stage III and IV coma treated with this combined regimen indicates that further studies should be done to confirm this thesis.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 5","pages":"689-92"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009117338","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13253905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Novel endotoxin adsorbing materials, polymyxin-sepharose and polyporous polyethylene membrane for removal of endotoxin from dialysis systems. 新型内毒素吸附材料:多粘菌素-sepharose和多孔聚乙烯膜去除透析系统中的内毒素。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009119623
M Umeda, M Niwa, S Yamagami, T Kishimot, M Maekawa, Y Sawada
{"title":"Novel endotoxin adsorbing materials, polymyxin-sepharose and polyporous polyethylene membrane for removal of endotoxin from dialysis systems.","authors":"M Umeda,&nbsp;M Niwa,&nbsp;S Yamagami,&nbsp;T Kishimot,&nbsp;M Maekawa,&nbsp;Y Sawada","doi":"10.3109/10731199009119623","DOIUrl":"https://doi.org/10.3109/10731199009119623","url":null,"abstract":"<p><p>In order to remove contaminated endotoxin from dialysis systems, we prepared and investigated two novel endotoxin adsorbing materials, Polymyxin-Sepharose (PxSeph) and polyporous polyethylene hollow fiber membrane (EHF). PxSeph was prepared by covalently immobilizing polymyxin B on Sepharose 4B beads by CNBr coupling method. It adsorbed various endotoxins with a high affinity constant and could effectively remove endotoxin from aqueous solution and human plasma. EHF also removed endotoxins from contaminated water by filtration through EHF modules, and its adsorption nature was demonstrated. Both PxSeph and EHF are stable in physiological conditions and proved to be useful adsorbents for removal of contaminated endotoxin from the hemodialysis systems.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 4","pages":"491-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009119623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13436459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Encapsulation of liver microsomes--a further procedure for detoxication. 包封肝微粒体——进一步的解毒程序。
Biomaterials, artificial cells, and artificial organs Pub Date : 1990-01-01 DOI: 10.3109/10731199009119626
E Brugmann, J Strange, D Falkenhagen, W Dummler, B Ernst, H Dautzeberg
{"title":"Encapsulation of liver microsomes--a further procedure for detoxication.","authors":"E Brugmann,&nbsp;J Strange,&nbsp;D Falkenhagen,&nbsp;W Dummler,&nbsp;B Ernst,&nbsp;H Dautzeberg","doi":"10.3109/10731199009119626","DOIUrl":"https://doi.org/10.3109/10731199009119626","url":null,"abstract":"<p><p>Due to their partial permeability and their good mechanical properties, the symplex capsules are technically suited for an application in extracorporal detoxification. By this newly developed procedure the activity of encapsulated enzymes is considerably increased; thus, application for extracorporal detoxification seems to be advisable.</p>","PeriodicalId":77498,"journal":{"name":"Biomaterials, artificial cells, and artificial organs","volume":"18 4","pages":"513-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731199009119626","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13437109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书