The British journal of psychiatry. Supplement最新文献_第4页

Where next with residential alternatives to admission? 接下来会有什么住宿替代方案吗？

The British journal of psychiatry. Supplement Pub Date : 2010-08-01 DOI: 10.1192/bjp.bp.110.081125

Sonia Johnson, Brynmor Lloyd-Evans, Louise Howard, David P J Osborn, Mike Slade

引用次数: 0

Service users' experiences of residential alternatives to standard acute wards: qualitative study of similarities and differences. 服务使用者选择住宅替代标准急症病房的经验:异同的质性研究。

The British journal of psychiatry. Supplement Pub Date : 2010-08-01 DOI: 10.1192/bjp.bp.110.081075

Helen Gilburt, Mike Slade, Diana Rose, Brynmor Lloyd-Evans, Sonia Johnson, David P J Osborn

{"title":"Service users' experiences of residential alternatives to standard acute wards: qualitative study of similarities and differences.","authors":"Helen Gilburt, Mike Slade, Diana Rose, Brynmor Lloyd-Evans, Sonia Johnson, David P J Osborn","doi":"10.1192/bjp.bp.110.081075","DOIUrl":"https://doi.org/10.1192/bjp.bp.110.081075","url":null,"abstract":"Background: Little is known about the preferences and experiences of people with mental illness in relation to residential alternatives to hospital.Aims: To explore patients' subjective experiences of traditional hospital services and residential alternatives to hospital.Method: In-depth interviews were conducted with 40 purposively selected patients in residential alternative services who had previously experienced hospital in-patient stays. Transcripts were coded and analysed for thematic content.Results: Patients reported an overall preference for residential alternatives. These were identified as treating patients with lower levels of disturbance, being safer, having more freedom and decreased coercion, and having less paternalistic staff compared with traditional in-patient services. However, patients identified no substantial difference between their relationships with staff overall and the care provided between the two types of services.Conclusions: For patients who have acute mental illness but lower levels of disturbance, residential alternatives offer a preferable environment to traditional hospital services: they minimise coercion and maximise freedom, safety and opportunities for peer support.","PeriodicalId":77411,"journal":{"name":"The British journal of psychiatry. Supplement","volume":"53 ","pages":"s26-31"},"PeriodicalIF":0.0,"publicationDate":"2010-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1192/bjp.bp.110.081075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29162959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 61

Duration of untreated psychosis and pathways to care in first-episode psychosis. Investigation of help-seeking behaviour in primary care. 首发精神病患者未治疗精神病的持续时间和治疗途径。初级保健中求助行为的调查。

The British journal of psychiatry. Supplement Pub Date : 2010-06-30 DOI: 10.1002/9781444318814.CH2

A. Skeate, C. Jackson, M. Birchwood, Chris Jones

{"title":"Duration of untreated psychosis and pathways to care in first-episode psychosis. Investigation of help-seeking behaviour in primary care.","authors":"A. Skeate, C. Jackson, M. Birchwood, Chris Jones","doi":"10.1002/9781444318814.CH2","DOIUrl":"https://doi.org/10.1002/9781444318814.CH2","url":null,"abstract":"BACKGROUND\u0000Studies have consistently found that many individuals with first-episode psychosis experience significant delays before receiving treatment. Current research investigating treatment delays has focused on the relationship between demographic factors and duration of untreated psychosis (DUP). However, treatment-seeking behaviours in this group have not been investigated.\u0000\u0000\u0000AIMS\u0000To examine psychological processes that influence the decision-making process to contact primary care, in individuals with emerging psychosis.\u0000\u0000\u0000METHOD\u0000The influence of coping style, health locus of control and past health help-seeking behaviour on DUP was investigated in clients with a first episode of psychosis. This involved scrutiny of general practitioner (GP) records in an average of 6 years before the first treatment.\u0000\u0000\u0000RESULTS\u0000Shorter DUP was associated with more frequent GP attendance in the 6 years before the onset of psychosis and lower health threat avoidant coping scores.\u0000\u0000\u0000CONCLUSIONS\u0000Patients with short DUP have history of higher contact with their GP and, as a group, tend not to avoid health threats. The study underlines the importance of engaging young people and their families with primary care as one of a series of strategies to reduce DUP.","PeriodicalId":77411,"journal":{"name":"The British journal of psychiatry. Supplement","volume":"42 2","pages":"s73-7"},"PeriodicalIF":0.0,"publicationDate":"2010-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50789486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 34

Historical perspective on antipsychotic long-acting injections. 抗精神病长效注射的历史回顾。

The British journal of psychiatry. Supplement Pub Date : 2009-11-01 DOI: 10.1192/bjp.195.52.s7

D A W Johnson

引用次数: 72

Psychopharmacology and adverse effects of antipsychotic long-acting injections: a review. 抗精神病长效注射剂的精神药理学和不良反应:综述。

The British journal of psychiatry. Supplement Pub Date : 2009-11-01 DOI: 10.1192/bjp.195.52.s13

David Taylor

{"title":"Psychopharmacology and adverse effects of antipsychotic long-acting injections: a review.","authors":"David Taylor","doi":"10.1192/bjp.195.52.s13","DOIUrl":"https://doi.org/10.1192/bjp.195.52.s13","url":null,"abstract":"Background: Depot antipsychotics are widely used in clinical practice. Long-acting formulations of second-generation antipsychotics are now being developed and introduced.Aims: To review the pharmacology, pharmacokinetics and adverse effect profiles of currently available antipsychotic long-acting injections (LAIs).Method: The psychopharmacological properties of first- and second-generation antipsychotic LAIs are reviewed using data available up to October 2008.Results: First-generation antipsychotic (FGA) LAIs are associated with a high rate of acute and chronic movement disorders. Risperidone LAI is better tolerated in this respect, but is associated with hyperprolactinaemia and weight gain. Olanzapine LAI causes weight gain and other metabolic effects but appears not to be associated with an important incidence of movement disorders.Conclusions: Dosing of LAIs is complicated by delayed release of drug, changes in plasma levels without change in dose, and by the lack of data establishing clear dose requirements. All LAIs offer the prospect of assured adherence (although patients may still default on treatment) but their use is complicated by adverse effects, complex pharmacokinetics and confusion over dose-response relationships.","PeriodicalId":77411,"journal":{"name":"The British journal of psychiatry. Supplement","volume":"52 ","pages":"S13-9"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1192/bjp.195.52.s13","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28481243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 118

Antipsychotic long-acting injections: prescribing practice in the UK. 抗精神病长效注射:英国的处方实践。

The British journal of psychiatry. Supplement Pub Date : 2009-11-01 DOI: 10.1192/bjp.195.52.s37

Thomas R E Barnes, Amber Shingleton-Smith, Carol Paton

{"title":"Antipsychotic long-acting injections: prescribing practice in the UK.","authors":"Thomas R E Barnes, Amber Shingleton-Smith, Carol Paton","doi":"10.1192/bjp.195.52.s37","DOIUrl":"https://doi.org/10.1192/bjp.195.52.s37","url":null,"abstract":"Background: Data from the USA, Australia and Europe suggest that the proportion of patients with schizophrenia prescribed an antipsychotic long-acting injection (LAI) varies from around a quarter to a third. Use of LAIs has been associated with male gender and younger age.Aims: To characterise the use of LAIs in people with schizophrenia in three clinical settings in the UK.Method: The study used audit data from quality improvement programmes conducted by the Prescribing Observatory for Mental Health.Results: Long-acting injections were found to be prescribed for between a quarter and a third of patients, depending on the clinical setting. Flupentixol, risperidone and zuclopenthixol were most commonly prescribed and were combined with an oral antipsychotic in half of cases, frequently constituting high-dose prescribing. The use of LAIs was not consistently associated with age, gender or ethnicity.Conclusions: Antipsychotic LAIs are commonly prescribed. We did not replicate previous findings with respect to demographic variables associated with their use.","PeriodicalId":77411,"journal":{"name":"The British journal of psychiatry. Supplement","volume":"52 ","pages":"S37-42"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1192/bjp.195.52.s37","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28481246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 108

Clinical guideline recommendations for antipsychotic long-acting injections. 抗精神病长效注射剂的临床指南建议。

The British journal of psychiatry. Supplement Pub Date : 2009-11-01 DOI: 10.1192/bjp.195.52.s63

John M Kane, Carlos Garcia-Ribera

{"title":"Clinical guideline recommendations for antipsychotic long-acting injections.","authors":"John M Kane, Carlos Garcia-Ribera","doi":"10.1192/bjp.195.52.s63","DOIUrl":"https://doi.org/10.1192/bjp.195.52.s63","url":null,"abstract":"Background: Long-acting injections (LAIs) of antipsychotic drugs were developed over 40 years ago in an attempt to improve the long-term treatment of schizophrenia.Aims: To review existing guidelines concerning antipsychotic use generally, and LAIs in particular, and how patients might be identified as potential candidates for LAI treatment.Method: Literature review.Results: Currently several first-generation and one second-generation antipsychotic LAIs are available, with others under development. Although the use of LAIs is widespread around the world, patterns of use vary widely. Important considerations regarding the use of LAIs include the indications for long-term pharmacotherapy in schizophrenia in general, the indications for LAIs, the risks associated with LAIs, the need to update guidelines and the issue of cost.Conclusions: The use of these injections in first-episode psychosis and treatment-refractory schizophrenia is not currently a focus of recommendations, but should be considered. Long-acting injections remain an underutilised option in many countries despite frequent non-adherence with oral medication and subsequent relapse.","PeriodicalId":77411,"journal":{"name":"The British journal of psychiatry. Supplement","volume":"52 ","pages":"S63-7"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1192/bjp.195.52.s63","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28481162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 145

Antipsychotic long-acting injections: mind the gap. 抗精神病长效注射剂:注意空隙。

The British journal of psychiatry. Supplement Pub Date : 2009-11-01 DOI: 10.1192/bjp.195.52.s1

Maxine X Patel, Mark Taylor, Anthony S David

引用次数: 80

Knowledge about antipsychotic long-acting injections: bridging that gap. 关于抗精神病长效注射的知识:弥合这一差距。

The British journal of psychiatry. Supplement Pub Date : 2009-11-01 DOI: 10.1192/bjp.195.52.s5

Tom Burns

引用次数: 11

First-generation antipsychotic long-acting injections v. oral antipsychotics in schizophrenia: systematic review of randomised controlled trials and observational studies. 第一代抗精神病长效注射与口服抗精神病药物治疗精神分裂症：随机对照试验和观察性研究的系统回顾

The British journal of psychiatry. Supplement Pub Date : 2009-11-01 DOI: 10.1192/bjp.195.52.s20

Peter M Haddad, Mark Taylor, Omair S Niaz

{"title":"First-generation antipsychotic long-acting injections v. oral antipsychotics in schizophrenia: systematic review of randomised controlled trials and observational studies.","authors":"Peter M Haddad, Mark Taylor, Omair S Niaz","doi":"10.1192/bjp.195.52.s20","DOIUrl":"10.1192/bjp.195.52.s20","url":null,"abstract":"Background: Antipsychotic long-acting injections (LAIs) are often used in an attempt to improve medication adherence in people with schizophrenia.Aims: To compare first-generation antipsychotic long-acting injections (FGA-LAIs) with first- and second-generation oral antipsychotics in terms of clinical outcome.Method: Systematic literature review.Results: A meta-analysis of randomised controlled trials (RCTs) showed no difference in relapse or tolerability between oral antipsychotics and FGA-LAIs but global improvement was twice as likely with FGA-LAIs. Four prospective observational studies were identified; two studies reported lower discontinuation rates for FGA-LAIs compared with oral medication and two found that outcome was either no different or better with oral antipsychotics. Mirror-image studies consistently showed reduced in-patient days and admissions following a switch from oral antipsychotics to FGA-LAIs.Conclusions: The results are variable and inconclusive. Some evidence suggests that FGA-LAIs may improve outcome compared with oral antipsychotics. Methodological issues may partly explain the variable results. Selective recruitment in RCTs and lack of randomisation in observational studies are biases against LAIs, whereas regression to the mean in mirror-image studies favours LAIs. In terms of future research, a long-term pragmatic RCT of an FGA-LAI against an oral antipsychotic, in patients with problematic adherence, would be of value.","PeriodicalId":77411,"journal":{"name":"The British journal of psychiatry. Supplement","volume":"52 ","pages":"S20-8"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28481244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0