{"title":"[The characteristics of the anti-infectious defenses in newborn infants].","authors":"C Arion, V Popescu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors reviewed the up to date conceptions concerning the temporary alterations of the host defense mechanisms in the neonatal period (natural barriers, macrophages, complement system, cell-mediated and humoral immunity). They try to establish correlations between this temporary alterations and the high infectious risk and the severity of most of the infections in the newborn. A special attention is paid to the peculiar situation of the premature, and also to the modifications needed in the therapeutic schedules for serious neonatal infections.</p>","PeriodicalId":77318,"journal":{"name":"Pediatrie (Bucharest, Romania)","volume":"41 3","pages":"15-24"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12500357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Exocrine pancreas involvement in chronic enteropathies in infants and children].","authors":"N Miu, S Lakatoş","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>On a number of 135 cases of chronic enteropathies in patients aged 6 months--15 years, the trypsin, amilasis and lipasis levels in duodenal aspirate were investigated. In a high number, the decrease of pancreatic enzymes activity was noted and the majority of cases were accompanied by a marked dystrophy (grades II or III). Thus, it was not possible to indicate whether the low levels were primary or secondary determined.</p>","PeriodicalId":77318,"journal":{"name":"Pediatrie (Bucharest, Romania)","volume":"41 3","pages":"66-9"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12554347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Progress in neonatal screening for genetic diseases of metabolism].","authors":"V Popescu, A Zamfirescu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The main inborn errors of metabolism are described and the methods used for their screening. The recent technical progress in the screening tests are envisaged as well as the diagnosis and treatment aspects, insisting upon the fact that the neonatal screening undertaken in this areas are of vital importance, since the treatment of a number of specific inborn errors of metabolism constitutes a main trait of actual preventive pediatrics.</p>","PeriodicalId":77318,"journal":{"name":"Pediatrie (Bucharest, Romania)","volume":"41 3","pages":"25-35"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12500358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Arterial hypertension in children. II. The pathogenetic mechanisms involved in arterial hypertension and the therapeutic correlates].","authors":"D Moraru","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author discussed the principal pathological mechanisms of the essential hypertension, i.e the importance of sodium and natriuretic factor, the importance of the sympathetic nervous system in the adjustment of the blood pressure, the importance of the renin-angiotensin-aldosterone system, as well as the implication of the kidney by its pressor and depressor mechanisms. The authors emphasized the interrelation of the pressor mechanisms in the essential hypertension. He concluded that the essential hypertension is a \"disease of a complex adjustment\" with a clinical, biological, haemodynamic and therapeutic heterogeneity, that the genetic factor is well accepted, thus the identification of other genetic markers would have a great importance. There are also presented the principal groups of drugs used in the essential hypertension, in correlation with the pathological mechanisms.</p>","PeriodicalId":77318,"journal":{"name":"Pediatrie (Bucharest, Romania)","volume":"41 3","pages":"46-59"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12500361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Constitutional thrombocytopathies].","authors":"V Popescu, A Antrasian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper reports, starting from recent data in the literature, an important aspect in a pediatric practice, referring to the congenital qualitative platelet disorders. The authors present a modern classification of platelet disorders, based on functional and biochemical defects: defects of adhesion, of primary aggregation, abnormalities of secretion and procoagulant activity. It is discussed the pathogeny, clinical aspects and laboratory tests of each disease. The authors also present some entities recently individualised an the basis of the most topical literature data and the treatment means used, the evolution and prognosis.</p>","PeriodicalId":77318,"journal":{"name":"Pediatrie (Bucharest, Romania)","volume":"41 3","pages":"3-14"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12500360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The evolutionary profile of HIV infection in children].","authors":"R Mătuşa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The evolution of HIV infection in children is bimodal, not depending on the vertical or horizontal route of transmission and with no assemblence with AIDS evolution in adults. The contaminated children with fast evolution to death in maximum two years, develop a severe neurological and infectious symptomatology. The others even symptomatic show slowly evolution with not so frequent and not so serious acute infectious. The natural history of the HIV infection in children of our country will be better defined in the future for now it is observed only for three years.</p>","PeriodicalId":77318,"journal":{"name":"Pediatrie (Bucharest, Romania)","volume":"41 3","pages":"70-2"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12500364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Lipid metabolism in severely acute diarrheic disease in infants].","authors":"V Lupu, D Popa, M Damian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a group of 34 infants with serious acute diarrheic disease, the authors study the total lipids, total and esterified cholesterol, triglycerides and lipidogram, in the acute phase of the disease and at a 10-day-interval from the first determination. Triglycerides have constantly increased values both at admittance and at the second determination, as a consequence of lipid mobilization in acute stage. This process continues due to the hypolipidic and hypocaloric diet. Esterified fraction of cholesterol has initially important decreases, tending to become normal in the interval studies, more evident in the healthy infant. Total lipids are increased in 10.5% of the cases and the lipidogram shows an increase of alpha-lipoproteins and prebeta-lipoproteins in 10.5% and 17.5% respectively of the cases in the first determination.</p>","PeriodicalId":77318,"journal":{"name":"Pediatrie (Bucharest, Romania)","volume":"41 2","pages":"45-51"},"PeriodicalIF":0.0,"publicationDate":"1992-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12500983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}