[Constitutional thrombocytopathies].

Abstract

The paper reports, starting from recent data in the literature, an important aspect in a pediatric practice, referring to the congenital qualitative platelet disorders. The authors present a modern classification of platelet disorders, based on functional and biochemical defects: defects of adhesion, of primary aggregation, abnormalities of secretion and procoagulant activity. It is discussed the pathogeny, clinical aspects and laboratory tests of each disease. The authors also present some entities recently individualised an the basis of the most topical literature data and the treatment means used, the evolution and prognosis.