Science China Chemistry最新文献

{"title":"Uranium extraction from seawater: methods and challenges","authors":"Zhenli Sun,&nbsp;Zhongshan Chen,&nbsp;Xishi Tai,&nbsp;Xiangke Wang","doi":"10.1007/s11426-025-2784-1","DOIUrl":"10.1007/s11426-025-2784-1","url":null,"abstract":"<div><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 9","pages":"3923 - 3926"},"PeriodicalIF":9.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transglycosylases in peptidoglycan biosynthesis: advances in structure, function, and antimicrobial development","authors":"Xiao-Lin Zhang,&nbsp;Han Ding,&nbsp;Aoxin Guo,&nbsp;Xue-Wei Liu","doi":"10.1007/s11426-024-2601-y","DOIUrl":"10.1007/s11426-024-2601-y","url":null,"abstract":"<div><p>Peptidoglycan (PG), the essential exoskeleton in most bacteria, is synthesized through the action of bacterial transglycosylases (TGases), positioning these enzymes as elegant and desirable targets for antibiotic discovery. This review covers the major TGases involved in PG biogenesis, including TGases from the glycosyltransferase family 51 (GT51) and the newly discovered shape, elongation, division, sporulation (SEDS) family. We discuss the distinct roles of these two TGases during PG synthesis and emphasize the structural and catalytic differences, highlighting their coordination in PG assembly. Moreover, we summarize recent advances in TGase-involved antimicrobial strategies, including substrate-mimicking TGase inhibitors, PG terminators, and TGase-related immunological therapy targeting TGase from the GT51 family, and the first non-substrate-like TGase inhibitor against the SEDS protein. These valuable insights pave the way for the further development of novel TGase-related antimicrobial agents.\u0000</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 9","pages":"4012 - 4024"},"PeriodicalIF":9.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new oxaliplatin(IV) prodrug inducing ferroptosis through a triple-pathway mechanism and activating anti-cancer immunity","authors":"Xinda Yang,&nbsp;Nan Huang,&nbsp;Mingyang Li,&nbsp;Xiaoli Zhu,&nbsp;Chunhui Wang,&nbsp;Yue Zhang,&nbsp;Chuansheng Xu,&nbsp;Niantong Yang,&nbsp;Sirui Chen,&nbsp;Yuheng Pan,&nbsp;Bing Shen,&nbsp;Shuo Shi","doi":"10.1007/s11426-024-2683-9","DOIUrl":"10.1007/s11426-024-2683-9","url":null,"abstract":"<div><p>Ferroptosis inducers exhibit great potential as anticancer drugs but face two key challenges: (1) non-selective toxicity toward both tumor and immune cells may suppress antitumor immunity; (2) tumor resistance driven by antioxidant defense mechanisms or iron metabolism regulation reduces therapeutic efficacy. To address these issues, herein, a new oxaliplatin(IV) prodrug FAOP by coupling artesunate (ART) and (3-carboxypropionyl) ferrocene (ferrocene fragments) was rationally designed. FAOP could release oxaliplatin (OP), ART and ferrocene fragments, exerting a synergistic anti-cancer effect. Firstly, ferrocene fragments would induce ferroptosis by catalyzing Fenton reaction to generate hydroxyl radicals (·OH), causing lipid peroxidation. Secondly, ART inhibited GPX4 by reducing glutathione (GSH) levels and generating reactive oxygen species (ROS), thereby disrupting the redox balance and further sensitizing cells to ferroptosis. Lastly, OP could induce apoptosis while synergizing with intracellular ROS, resulting in enhanced immunogenic cell death (ICD) and activating both innate and adaptive immunity. The immune effector-activated CD8⁺ T cells produced IFN-γ, which inhibited the cystine transport by tumor cells, further impaired GPX4 activation and sensitized ferroptosis. The mutual reinforcement strategy of ICD and ferroptosis mediated by FAOP could overcome the limitations of traditional chemotherapy and reverse immunosuppression caused by ferroptosis inducers, offering a novel idea for designing ferroptosis inducers.\u0000</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 9","pages":"4297 - 4310"},"PeriodicalIF":9.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrocatalytic upcycling of plastics-derived ethylene glycol to carbon-chain-propagated C3+ α-hydroxycarboxylic acids","authors":"Shuoshuo Guo,&nbsp;Huizhi Li,&nbsp;Bin Zhang","doi":"10.1007/s11426-025-2796-6","DOIUrl":"10.1007/s11426-025-2796-6","url":null,"abstract":"","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 8","pages":"3345 - 3346"},"PeriodicalIF":9.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145169474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interfacial modulation engineering for sodium layered oxide cathode: air stability, ion-transfer kinetics, and phase evolution","authors":"Qi-Cong Ling,&nbsp;Qing-Qun Sun,&nbsp;Yan-Jiang Li,&nbsp;Zhuo-Zheng Hong,&nbsp;Han-Shen Xin,&nbsp;Xin-Yu Liu,&nbsp;Yan-Fang Zhu,&nbsp;Shi-Xue Dou,&nbsp;Yao Xiao","doi":"10.1007/s11426-024-2725-6","DOIUrl":"10.1007/s11426-024-2725-6","url":null,"abstract":"<div><p>Sodium-ion batteries (SIBs) have garnered significant attentions for grid-scale energy storage due to the low cost and abundant sodium resources. Among the various cathode materials, sodium layered transition metal oxides (Na_<i>x</i>TMO₂) are considered highly promising for practical applications of SIBs relying on their high theoretical capacities and facile syntheses. However, the poor air stability, sluggish interfacial kinetics, and detrimental phase transitions of Na_<i>x</i>TMO₂ commonly result in unsatisfactory cycling stability as well as inferior rate capability. In this review, recent achievements and progress in interfacial regulations aimed at improving the air stability and electrochemical performances of Na_<i>x</i>TMO₂, such as organic/inorganic coating, interfacial-coating-doping, and heterogeneous phase designing are summarized. Such approaches can not only enable the <i>in-situ</i> conversion of residual alkali and/or enhance the interfacial stability, but also improve the electrochemical reaction kinetics and mitigate phase evolutions. The structural stability enhancement mechanisms of Na_<i>x</i>TMO₂ layered oxides resulted from surface reconstructions are profoundly discussed and the influences on their electrochemical properties are concluded in this work. Finally, we outlook the novel interfacial modification strategies like of layered-tunnel heterostructure building and organic-inorganic co-coating. The state-of-the-art characterization techniques and artificial intelligence are also elaborated to develop high-performance Na_<i>x</i>TMO₂ cathodes in the future. We believe that the insights presented in this review can serve as meaningful guidance for the interfacial modulations of Na_<i>x</i>TMO₂ cathodes.\u0000</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 9","pages":"4068 - 4090"},"PeriodicalIF":9.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distance effect of carbon defects as design principles for metal-free oxygen reduction electrocatalysts","authors":"Yun Han,&nbsp;Xin Mao,&nbsp;Xuecheng Yan,&nbsp;Qilong Wu,&nbsp;Qingchao Fang,&nbsp;Yi Jia,&nbsp;Qin Li,&nbsp;Xiangdong Yao,&nbsp;Aijun Du","doi":"10.1007/s11426-024-2705-2","DOIUrl":"10.1007/s11426-024-2705-2","url":null,"abstract":"<div><p>The experimental design of defective carbon-based catalysts currently mainly focuses on the arrangement and combination of various types of defects. The distance effect of defects and defect-defect interaction on the oxygen reduction reaction (ORR) catalytic activity remains fully unexplored. Herein, we first investigated the potential effect of inter-defect distance on ORR activity along zigzag and armchair directions through density functional theory (DFT) calculations, and pronounced catalytic activity anisotropy was observed. The shortest inter-defect distance along the zigzag distance results in the highest ORR activity with an ORR overpotential of 0.50 V on the Stone-Wales defect. While the shortest inter-defect distance along the armchair direction cannot influence or even impede the ORR process. Meanwhile, restricting the expansion of intra-defect distance caused by variations in the inter-defect distance could further enhance the ORR activity with an ultralow overpotential of 0.43 V on the C585 defect. Furthermore, the <i>p</i>_<i>z</i> band centers of carbon active sites exhibit a linear relationship with the binding strength of O intermediates, which can be a good catalytic descriptor to describe the ORR activity of carbon defects. Our findings highlight interesting avenues for controllable design and synthesis of catalysts in the field of high-density defect catalysis.\u0000</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 9","pages":"4183 - 4193"},"PeriodicalIF":9.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supramolecular host-guest recognition enables X-ray structure determination of “stubborn” molecules","authors":"Jian Yang,&nbsp;Qing-Fu Sun","doi":"10.1007/s11426-025-2778-y","DOIUrl":"10.1007/s11426-025-2778-y","url":null,"abstract":"","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 8","pages":"3338 - 3339"},"PeriodicalIF":9.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145169065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning in photocatalysis: accelerating design, understanding, and environmental applications","authors":"Siqing Tunala,&nbsp;Shaochong Zhai,&nbsp;Fangcao Wu,&nbsp;Yi-Hung Chen","doi":"10.1007/s11426-024-2656-6","DOIUrl":"10.1007/s11426-024-2656-6","url":null,"abstract":"<div><p>Photocatalysis is a transformative strategy with wide applications in environmental remediation, energy conversion, and chemical synthesis. However, optimizing photocatalysts is challenging due to the complex interplay of factors like material composition, light absorption, and surface reactivity. Traditional trial-and-error approaches are time-consuming and resourceintensive, often requiring extensive experimentation under varied conditions. Machine learning (ML) has recently emerged as a powerful tool to accelerate photocatalyst discovery and optimization. By analyzing large datasets, ML algorithms can predict material properties, identify optimal reaction conditions, and reduce the need for exhaustive experimentation. This data-driven approach enables faster exploration of complex chemical spaces and reaction environments. This review focuses on recent advancements in integrating ML into photocatalysis, emphasizing its role in catalyst design and environmental applications. It also addresses key challenges such as data quality and model interpretability while highlighting future research directions to fully harness the potential of ML in photocatalytic systems.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 8","pages":"3415 - 3428"},"PeriodicalIF":9.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145169064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circular 3D photo-printing: the future of sustainable additive manufacturing","authors":"Da-Hui Qu,&nbsp;He Tian","doi":"10.1007/s11426-025-2749-0","DOIUrl":"10.1007/s11426-025-2749-0","url":null,"abstract":"","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 8","pages":"3340 - 3341"},"PeriodicalIF":9.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145168723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-assembly of 2D Kagome superlattices governed by curvature-guided depletion interactions","authors":"Huihong Li,&nbsp;Datao Tu,&nbsp;Xueyuan Chen","doi":"10.1007/s11426-025-2733-5","DOIUrl":"10.1007/s11426-025-2733-5","url":null,"abstract":"","PeriodicalId":772,"journal":{"name":"Science China Chemistry","volume":"68 8","pages":"3335 - 3337"},"PeriodicalIF":9.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145168694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}