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Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress最新文献

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[Regeneration of hyalin cartilage in the knee joint by treatment with autologous chondrocyte transplants--initial clinical results]. 【自体软骨细胞移植治疗膝关节透明质软骨再生——初步临床结果】。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
J Löhnert
{"title":"[Regeneration of hyalin cartilage in the knee joint by treatment with autologous chondrocyte transplants--initial clinical results].","authors":"J Löhnert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Treatment with autologous chondrocyte transplantation (ACT) leads to regeneration of hyaline cartilage. Since September 1996, 52 patients have been treated. Eleven patients were screened clinically and by MRI 18 months later. The biopsy specimen from the transplanted area showed formation of hyaline cartilage.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"1205-7"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20837684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Online infection recording within the scope of total quality management]. 【全面质量管理范围内的在线感染记录】。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
M Ehlebracht, M Birth, M Hilbert, H F Weiser
{"title":"[Online infection recording within the scope of total quality management].","authors":"M Ehlebracht,&nbsp;M Birth,&nbsp;M Hilbert,&nbsp;H F Weiser","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The continuous and exact recording of infections is a condition sine qua non for total quality management. Therefore, at the Diakoniekrankenhaus Rotenburg (Wümme) a program which offers the possibility of online recording of data was integrated into the hospital intranet. The recording is done with network clients. The recording of data is supported by a series of plausibility controls. The advantage consists in immediate evaluation of up to date and extensive statistics of infections. By integration into the existing system, relevant influences and consequences such as the prolongation of hospitalisation, use of material, and frequency of reoperation can by recognized and immediately considered with high validity.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"847-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20837746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Estimation for bugeting and evaluation of surgical procedures within the scope of comparative hospital administration. Value of LKA, PPR and DRG systems]. [比较医院管理范围内外科手术的预算和评价估算。LKA, PPR和DRG系统的价值]。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
R Pinnau, K Rostock, R Gudath, T Mansky, U Meyer-Pannwitt
{"title":"[Estimation for bugeting and evaluation of surgical procedures within the scope of comparative hospital administration. Value of LKA, PPR and DRG systems].","authors":"R Pinnau,&nbsp;K Rostock,&nbsp;R Gudath,&nbsp;T Mansky,&nbsp;U Meyer-Pannwitt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Comparison of costing and performances of individual departments or hospitals are required by the statute book of social affairs (Sozialgesetzbuch V; SGB V), but have not been fully introduced in Germany. LBK Hamburg, a trust of 8 hospitals with 17 surgical departments, evaluated the significance of performance and cost-accounting systems such as performance and cost-accounting (LKA), nursing staff regulation (PPR), and the diagnosis-related group system in order to distribute a three-year budget (1996-1998) and to compare, e.g., performance of surgical departments. The DRG system seems to be the best choice, since it weights all cases by means in 640 groups according to the degree of difficulty. With a given closed budget, the DRG system may compare the actual cost with the target figures.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"864-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20837750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Detection of hepatic micrometastasis in ductal pancreatic carcinoma by K-ras mutation analysis and determination of clinical relevance]. [应用K-ras突变分析检测导管性胰腺癌肝微转移及临床意义的探讨]。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
D Bastian, B Gerdes, A Ramaswamy, C Tschammer, D Bartsch
{"title":"[Detection of hepatic micrometastasis in ductal pancreatic carcinoma by K-ras mutation analysis and determination of clinical relevance].","authors":"D Bastian,&nbsp;B Gerdes,&nbsp;A Ramaswamy,&nbsp;C Tschammer,&nbsp;D Bartsch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this prospective study we evaluated the presence and importance of hepatic micrometastases at the time of operation in patients with resectable pancreatic carcinoma. In 13 patients with pancreatic carcinoma and 5 patients with chronic pancreatitis Truecut-Needle biopsies of the liver were obtained during operation. K-ras mutation analysis was done by the PCR/restriction digestion assay with HphI, followed by an ultrasound of the liver in 3 monthly intervals. Four of 13 (30%) pancreatic cancer patients had K-ras gene mutations in the liver and had a mean survival of 6 months after resection. All chronic pancreatitis patients and 8 of the 9 remaining pancreatic cancer patients without K-ras mutations in the liver biopsies are alive without evidence of liver metastases after a mean follow-up of 9 months. Detection of micrometastases in the liver by K-ras mutation analysis might be a powerful tool to identify occult clinical relevant liver metastases.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 Suppl I","pages":"45-7"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40830634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Disorders of hepatic microcirculation as early manifestation of rejection in clinical liver transplantation]. 肝微循环障碍是临床肝移植排斥反应的早期表现。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
E Klar, M Angelescu, C Zapletal, W Hofmann, T Kraus, C Herfarth
{"title":"[Disorders of hepatic microcirculation as early manifestation of rejection in clinical liver transplantation].","authors":"E Klar,&nbsp;M Angelescu,&nbsp;C Zapletal,&nbsp;W Hofmann,&nbsp;T Kraus,&nbsp;C Herfarth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By means of thermodiffusion, monitoring of hepatic microcirculation was performed in 43 patients during the first week after liver transplantation. A significant decrease of liver perfusion was registered in 15 patients with early rejection. The disturbance of hepatic microcirculation preceded the increase of transaminases by 36 hours and the subsequent biopsy by 60 hours. Already 12 hours after the beginning of corticoid therapy liver perfusion started to recover. The quantification of hepatic microcirculation may facilitate faster diagnosis and treatment of early rejection following liver transplantation.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 Suppl I","pages":"371-5"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40830644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Endothelin receptor block in acute pancreatitis--improvement of microcirculation and decrease of capillary permeability also distant from the pancreas]. [内皮素受体阻断急性胰腺炎-微循环改善和远端毛细血管通透性降低]。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
T Foitzik, H G Hotz, G Eibl, J Faulhaber, M Kirchengast, H J Buhr
{"title":"[Endothelin receptor block in acute pancreatitis--improvement of microcirculation and decrease of capillary permeability also distant from the pancreas].","authors":"T Foitzik,&nbsp;H G Hotz,&nbsp;G Eibl,&nbsp;J Faulhaber,&nbsp;M Kirchengast,&nbsp;H J Buhr","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have previously demonstrated that therapy with a new specific endothelin-1 receptor antagonist (ET-RA) significantly reduced mortality in acute necrotizing pancreatitis (ANP) in the rat. Improved survival was not associated with decreased intrapancreatic trypsinogen activation or parenchymal necrosis but with reduced fluid sequestation into the third space suggesting that ET-RA counteracts systemic rather than local sequelae of severe pancreatitis. The present study further tests this hypothesis by evaluating the effect of the specific ET-1 antagonist LU-135252 on capillary blood flow, capillary density, and capillary permeability not only in the pancreas but also in the colon, and monitoring fluid losses and renal and respiratory function. The experiments demonstrate that therapy with the specific ET-RA started 6 hours after disease onset stabilizes increased capillary permeability in ANP not only in the pancreas but also in the colon. This is associated with reduced ascites and improved renal and respiratory function. Furthermore, ET-RA enhances decreased capillary blood flow and capillary density in the pancreas and colon. The present results are consistent with our previous observation that ET-RA improves outcome in ANP by counteracting systemic microcirculatory disorders (particularly capillary leakage) which are believed to contribute to organ failure in early pancreatitis in this model as well as in severe human pancreatitis.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 Suppl I","pages":"427-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40831102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[New aspects of anti-inflammatory potential of AT III: reduction of reperfusion injury after warm liver ischemia]. [AT III抗炎潜能的新进展:减轻肝热缺血后再灌注损伤]。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
S M Maksan, M M Gebhard, M O Maksan, C Herfarth, E Klar
{"title":"[New aspects of anti-inflammatory potential of AT III: reduction of reperfusion injury after warm liver ischemia].","authors":"S M Maksan,&nbsp;M M Gebhard,&nbsp;M O Maksan,&nbsp;C Herfarth,&nbsp;E Klar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hepatic microcirculation after warm hepatic ischemia in rats can be significantly enhanced by Antithrombin III. The number of sinusoidal stickers as a tool for characterizing the leukocyte-endothelial cell interaction was significantly reduced. The peak of serum transaminases as an indicator of hepatocellular damage was significantly decreased after the AT III application. It has to be concluded that AT III application before Pringle maneuver might significantly reduce the reperfusion damage after liver resection.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 Suppl I","pages":"383-5"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40831146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Reduction of local and systemic complications of acute pancreatitis by monoclonal antibody to ICAM-1]. [ICAM-1单克隆抗体减少急性胰腺炎的局部和全身并发症]。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
J Werner, W Hartwig, E Schmidt, M M Gebhard, C Herfarth, E Klar
{"title":"[Reduction of local and systemic complications of acute pancreatitis by monoclonal antibody to ICAM-1].","authors":"J Werner,&nbsp;W Hartwig,&nbsp;E Schmidt,&nbsp;M M Gebhard,&nbsp;C Herfarth,&nbsp;E Klar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The prognosis of acute necrotizing pancreatitis is dependent on systemic complications. The endothelial adhesion molecule ICAM-1 mediates both leukocyte adhesion and migration. Expression of ICAM-1 was investigated at various time points in mild and severe necrotizing pancreatitis in the pancreas, lungs and intestine. A possible therapeutic effect of monoclonal antibodies against ICAM-1 was evaluated in severe necrotizing disease. The expression of ICAM-1 preceded the fulminant leukocyte Infiltration of the organs. In contrast to mild pancreatitis, ICAM-1 expression was increased at an earlier time point and systemically in severe necrotizing disease. Treatment with antibodies against ICAM-1 improved microcirculation and reduced local and systemic organ damage in severe pancreatitis.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 Suppl I","pages":"725-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40831156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Role of endothelin-nitrogen monoxide equilibrium in ischemia/reperfusion damage of the liver]. 内皮素-一氧化氮平衡在肝脏缺血再灌注损伤中的作用。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
D Uhlmann, S Scommotau, H Witzigmann, J Hauss, H U Spiegel
{"title":"[Role of endothelin-nitrogen monoxide equilibrium in ischemia/reperfusion damage of the liver].","authors":"D Uhlmann,&nbsp;S Scommotau,&nbsp;H Witzigmann,&nbsp;J Hauss,&nbsp;H U Spiegel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Elevated levels of endothelin (ET) are measured during ischemia and reperfusion, but no adequate increase of nitric oxide (NO) can be observed. Thus, the balance of both substances, which occurs under physiological conditions and regulates microcirculatory vessel widths, is disturbed. This leads to microcirculatory damages. As well ET receptor blocking using a mixed ET receptor antagonist as increase of NO production after L-arginine treatment influenced this pathomechanism. The preischemic sinusoidal diameters were maintained and leukocyte endothelial interactions reduced. Concomitantly, sinusoidal perfusion rate and local hepatic tissue pO2 were increased. Because of significant reduced hepatocellular damage in both therapy groups both therapeutical ways might exert beneficial effects to attenuate ischemia/reperfusion induced microvascular and tissue injury.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 Suppl I","pages":"329-33"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40831289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of normal human hepatocytes in a hybrid organ system]. [在混合器官系统中使用正常人类肝细胞]。
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01
M K Auth, M Okamoto, Y Ichida, S H Auth, J Gerlach, A Encke, P McMaster, A J Strain
{"title":"[Use of normal human hepatocytes in a hybrid organ system].","authors":"M K Auth,&nbsp;M Okamoto,&nbsp;Y Ichida,&nbsp;S H Auth,&nbsp;J Gerlach,&nbsp;A Encke,&nbsp;P McMaster,&nbsp;A J Strain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using the bioreactor model developed by J. Gerlach, we examined the potential of normal human hepatocytes for application in bioartificial liver devices. From normal human donor livers 1.5 x 10(8) hepatocytes were isolated. Hepatocytes were perfused in a woven multi-compartment capillary system in serum-free culture medium containing ammoniachloride over a period of 2 weeks. These cells demonstrated a well differentiated ultrastructure with formation of junctional complexes and bile canaliculi between adjacent cells. During reactor run, a constant albumin synthesis with levels above 11 mg/ml and maintenance of urea production and lignocaine metabolism (MEGX-test) were detected. These initial results indicate that normal human hepatocytes express typical morphology and ultrastructure and are able to keep differentiated functions in suitable perfusion models. Combination of the distinct human liver cell populations might enable promotion of further specific functions (clotting factors) and induction of liver cell proliferation.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 Suppl I","pages":"665-8"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40831299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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