{"title":"[Primary liver and bile duct tumors: approach to conservative therapy].","authors":"D Henne-Bruns, H G Marks","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In case of non-resectable primary liver cancer the following treatment modalities can be applied: ligation, embolization or balloon occlusion of the hepatic artery, locoregional chemotherapy, percutaneous ethanol or acetic acid injection, microwave application, and cryotherapy, as well as combined therapeutic modalities. The 3-year survival rates for patients with small hepatocellular carcinomas (HCCs) are comparable for the different procedures (resection, ethanol- or acetic acid injection, cryotherapy, microwave application) and range between 60-80%. In patients with larger HCCs the prognosis seems to be improved by a combination treatment of chemoembolization and ethanol injection compared to chemoembolization alone.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"343-7"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20836294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Lempa, P Gerards, G Koch, S Sauerland, J Dietrich, E Vestweber, E Neugebauer
{"title":"[Efficacy of an Acute Pain Service--a controlled comparative study of hospitals].","authors":"M Lempa, P Gerards, G Koch, S Sauerland, J Dietrich, E Vestweber, E Neugebauer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The efficacy of an acute pain service was prospectively evaluated on elective abdominal operations by comparing two surgical departments including a total of 498 patients. The patients of the clinic with an acute pain service reported less pain (at rest and in movement) pre- and postoperatively and received more analgetics. They had more appetite, lower sleep requirements and more independence. The patients' overall satisfaction was greater in the clinic with an acute pain service.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"673-6"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20836803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Biological wound tissue glue systems in wound healing].","authors":"G B Stark, R E Horch, M Voigt, E Tanczos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tissue engineering relies on in vitro cell culture, biocompatible matrix materials and genetic engineering with growth and differentiation factors for guided tissue regeneration. Biogenic or semisynthetic biomaterials are an alternative as cell carriers: To circumvent the disadvantages of conventional keratinocyte sheet grafts, a keratinocyte fibrin glue suspension KFGS (H. W. Kaiser et al., Burns 20: 23, 1994), which mainly consists of epidermal stem cells, has been tested experimentally in nude mice and clinically in extensive burns and chronic wounds. In the \"in vivo culture\" on the wound, the non-confluent keratinocytes form a differentiated epithelium within days. Current research aims at guided dermal regeneration by a combination with allodermis or biomaterials (collagen sponges like TissueFaszie, Microspheres etc.). Fibrin glue (Tissuecol) has also been tested successfully as matrix for other cells like chondrocytes and fibroblasts transfected with growth factor genes (EGF/KGF).</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"683-8"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20836805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Intraoperative isotope-controlled probe localization after somatostatin receptor scintigraphy of occult neuroendocrine tumors].","authors":"N Runkel, M Bäder, B Wiedenmann, H J Buhr","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intraoperative gamma detection of GEP tumors with a manual probe following i.v. 111In-DTPA-D-Phe1-Pentetreotide is a new and expensive procedure. This study analyses its value in nine patients with occult lesions (undetected preoperatively). All lesions with the exception of a 8-mm liver metastasis were correctly diagnosed intraoperatively. The tumor/normal tissue ratios were in vivo 1.3 (1.1-2.0) and ex vivo 23.0 (9.4-24.0). False-positive results were obtained three times in vivo and once ex vivo. Sensitivity was 89% and specificity 57%, respectively. All lesions were successfully detected by careful surgical exploration. We conclude that intraoperative gamma detection offers little additional information over standard diagnostic procedures.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"1034-7"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20836814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pre- and postoperative ultrasound in reconstruction of finger flexor tendons in zone 2].","authors":"M Holch, S Rammelt, B Pflugk, H Zwipp","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty-five patients with 31 zone 2 flexor tendon injuries were evaluated prospectively by means of high-resolution ultrasonography and clinically. Results were assessed according to Buck-Gramcko's Strickland's, LMS and TAM score. Ultrasonic findings led to individual modifications (abbreviation or prolongation) of postoperative hand therapy and were helpful in decision making for secondary surgery like tenolysis or secondary repair.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"1288-91"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20836823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hypothetical and reliable aspects of pre-, intra- and postoperative adjuvant therapy of stomach carcinoma].","authors":"H J Meyer, G J Opitz, J Jähne, H Wilke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of surgical therapy of gastric cancer could not be improved in recent years. Therefore, different perioperative modalities were investigated for this tumor. A series of studies could not show any survival benefit using postoperative adjuvant radio- or chemotherapy after complete resection of the tumor. Data available about preoperative chemotherapy in locally advanced tumor stages may demonstrate an increased R0-resection rate after objective remission resulting in a prolonged survival compared to surgery alone. Furthermore, in others trials intraoperative radiation or intraperitoneal chemotherapy could decrease the incidence of locoregional recurrence or peritoneal carcinomatosis and improve the overall survival rate. These treatment modalities, above all preoperative chemotherapy, must be proven in precisely defined patient populations within prospective trials to achieve clearcut data in the future.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"312-7"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20836978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Basic molecular biology of colon and rectal carcinoma--when differential diagnosis?].","authors":"H K Schackert, C Kruppa, M Hahn","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Colorectal cancer (CRC) is one of the most common cancers in Western populations, striking both women and men at approximately equal rates. A genetic basis for the development of cancer has already been suggested by Karl Heinrich Bauer in 1928 but only since the advancement of molecular biology direct evidence has been obtained to support the notion that cancer is a genetic disease. Recent progress in our understanding of the molecular basis of the most prevalent colorectal cancer syndromes, such as hereditary nonpolyposis colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP), is reflected by modifications in diagnosis and therapy. Identification of genetic risk factors for the development of adenomas and associated carcinomas of the colon and rectum results in predictive molecular diagnosis of malignant disease and enables preventive treatment.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"318-22"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20836979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Basic principles and \"direct nerve\" reconstruction in brachial plexus paralysis].","authors":"P F Graf","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An exact knowledge of the complex anatomy of the brachial plexus is absolutely necessary to carry out this treatment. The most important diagnostic steps are: case history, examination, investigation of muscle function and sensitivity, myelo-CT, MRI, and neurophysiological investigations. The best time for operative revision is between the 6th week and the 3rd month. An individual therapy protocol must be established that includes a large spectrum of reconstructive options like nerve reconstructions, neurotizations, muscle and tendon transposition, muscle transplantation, arthrodesis, orthesis and others.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"547-9"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20837107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N M Meenen, B Rischke, P Adamietz, M Dauner, J Fink, C Göpfert, J M Rueger
{"title":"[Treatment of cartilage defects].","authors":"N M Meenen, B Rischke, P Adamietz, M Dauner, J Fink, C Göpfert, J M Rueger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Articular surface defects will not heal spontaneously. Localized defects, e.g., in the knee joint, should be treated with transplantation of autologous cells containing material of different composition. For transplantation of osteochondral pegs they are grafted from minor loaded joint areas and implanted into highly loaded defect regions. For autologous cartilage cell transplantation they are proliferated in vitro and then implanted into the defect zone under an periostal flap, harvested from the proximal tibia and sutured into the cartilage level around the defect. Autologous paste of cartilage and cancellous bone is transplanted into aggressively prepared defects with the concept of regrowing articular cartilage out of the transplanted cells and the subchondral bone.</p>","PeriodicalId":77239,"journal":{"name":"Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"115 ","pages":"568-76"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20837111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}