【软骨缺损的治疗】

N M Meenen, B Rischke, P Adamietz, M Dauner, J Fink, C Göpfert, J M Rueger
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引用次数: 0

摘要

关节面缺损不会自愈。局部缺陷,如膝关节,应采用含有不同成分材料的自体细胞移植治疗。对于骨软骨钉的移植,它们从小负荷的关节区域移植到高负荷的缺陷区域。对于自体软骨细胞移植,它们在体外增殖,然后在骨膜瓣下植入缺损区,从胫骨近端采集并缝合到缺损周围的软骨水平。自体软骨和松质骨膏体被移植到积极准备的缺损中,其概念是从移植细胞和软骨下骨中再生关节软骨。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Treatment of cartilage defects].

Articular surface defects will not heal spontaneously. Localized defects, e.g., in the knee joint, should be treated with transplantation of autologous cells containing material of different composition. For transplantation of osteochondral pegs they are grafted from minor loaded joint areas and implanted into highly loaded defect regions. For autologous cartilage cell transplantation they are proliferated in vitro and then implanted into the defect zone under an periostal flap, harvested from the proximal tibia and sutured into the cartilage level around the defect. Autologous paste of cartilage and cancellous bone is transplanted into aggressively prepared defects with the concept of regrowing articular cartilage out of the transplanted cells and the subchondral bone.

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