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[The goal-oriented project "pathology of environmental pollutants" (M.U.R.S.T. 40%)]. [目标导向项目“环境污染物病理学”(M.U.R.S.T. 40%)]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
G Ugazio
{"title":"[The goal-oriented project \"pathology of environmental pollutants\" (M.U.R.S.T. 40%)].","authors":"G Ugazio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study was to estimate to toxicity bound to effluent water, pore water and bed sediment sampled twice during 1994 (spring and autumn) from 16 tributaries of Po river. Toxicity was determined by using a battery of bioassays (Artemia salina, Dugesiagonocephala and Thamnocephalus platyurus) and a battery of phytoassays, including Oryza sativa and Triticum sativum. Results show that practically no toxicity is found in effluent water, mild adverse effects are obtained with sediment pore water, while the most harmful compounds are those bound to sediment particles. These data strengthen the hypothesis that sediment is the true historical memory of the ecotoxicological conditions of a water body. Finally, the map of our results illustrates that pollution severity is progressively increasing from western to eastern tributaries in Po river valley.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"5-10"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19954106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Concentration of asbestos fibers in urothelial tumors and in the neoplasm-free bladder wall]. [尿路上皮肿瘤和无肿瘤膀胱壁石棉纤维的浓度]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
L Pollice, G M Ferri, L Paoletti, A Gentile, U Iacobellis, D Batisti, P Di Tonno, G Caruso, R Molinini
{"title":"[Concentration of asbestos fibers in urothelial tumors and in the neoplasm-free bladder wall].","authors":"L Pollice,&nbsp;G M Ferri,&nbsp;L Paoletti,&nbsp;A Gentile,&nbsp;U Iacobellis,&nbsp;D Batisti,&nbsp;P Di Tonno,&nbsp;G Caruso,&nbsp;R Molinini","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of our study was to search the eventual presence of asbestos fibers in the neoplastic tissue of 13 cases of bladder carcinoma and in the normal vesical tissue of 12 control cases without neoplasia and operated upon for other urologic pathologies. To all patients a standardised questionnaire has been administered in order to ascertain the entity of the eventual exposition to asbestos. The organic component of the tissues has been oxidated at low temperature in atomic oxygen plasma and the residual inorganic component has been analysed by transmission electronic microscopy and energy dispersion spectrometry. We have found asbestos fibers only in two over the 25 examined samples; in both cases they belonged to patients affected by the neoplasia and in one of them also by pulmonary asbestos. The procedures that we used in this study, in respect to our other experiences, allowed us to reduce the risk of contamination of the tissues by asbestos, as it is shown by the lower number of cases with positive finding of fibers and by lower concentration of fibers in the positive cases.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19952045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Herbicides and neoplasms of the hemolymphopoietic system]. [除草剂与造血系统肿瘤]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
E Stagnaro, D Tiberti, G Panniza, M Vercelli
{"title":"[Herbicides and neoplasms of the hemolymphopoietic system].","authors":"E Stagnaro,&nbsp;D Tiberti,&nbsp;G Panniza,&nbsp;M Vercelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study is a population-based case-control study on hematolymphopoietic tumors, conducted in west Liguria with high prevalence of exposure to chemicals suspected (about 10%) of increasing the risk of leukaemias or lymphomas and multiple myeloma (pesticides). Cases and control were identified and confirmed during the period 1/1/1990 through 31/12/1993. Cases are identified through periodic contacts with the Pathology, or Hematology or other relevant Department of the Hospitals of west Liguria and Genoa town or University of Genoa where patients living in these area are referred for hematolymphopoietic malignancies. Controls are a random sample of the general population living in each area (using the demographic health archives). The range of the age is 20-74. After identification each case or control is contacted to have his consent to the interview near the home. Informations collected using a most completed questionnaire regard drinking and smoking habit, the addresses and the conditions of the homes where spending the life, particularly hobbies about exposure of pesticides and/or solvents, more important pathological events on the life and the occupational exposure. Actually we are in the phase of identification of cases and controls.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"17-8"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19952047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Goal-oriented projects of the Emilia Romagna region]. 【艾米利亚-罗马涅大区目标导向型项目】。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
M Biocca
{"title":"[Goal-oriented projects of the Emilia Romagna region].","authors":"M Biocca","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Region of Emilia Romagna, on the basis of a 1983 specific regional law, funded two triennal plans of applied health researches. The fundamental criteria and the characteristics of these two plans are described. A particular attention is devoted to the projects concerning environmental and occupational health. The role of the local occupational health services in performing research activities and in using the results of the research projects are also described.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"111-3"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19954098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Employment and alcohol: analysis of a clinical casuistic]. [就业与酒精:临床诡辩者的分析]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
G Biscaldi, G Vittadini, R Fonte, P Gabanelli, R Maglio, E Finozzi
{"title":"[Employment and alcohol: analysis of a clinical casuistic].","authors":"G Biscaldi,&nbsp;G Vittadini,&nbsp;R Fonte,&nbsp;P Gabanelli,&nbsp;R Maglio,&nbsp;E Finozzi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The relationship between alcohol and work was studied in a group of 537 voluntary patients (393 male and 144 female) admitted to the department of Medicina del Lavoro, Pavia University for alcohol rehabilitation. The highest incidence of alcohol abuse was found in non-working subjects (pensioners, unemployed, housewives) although the start of excessive drinking takes place after beginning a working activity; a cause-effect relationship between these two factors can not be clearly determined, however. It is true that the stress provoked by this new condition (introduction to the work experience) can, in certain subjects, be a contributing factor in alcohol abuse. The increasingly lower age of initiation to alcohol reconfirms the need for prevention and instruction even at scholastic level. We can deduce how no working condition, low age and low education can constitute makers of risk for alcohol abuse.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19953273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Participation of tachykinins in experimental models of lung damage]. [速激肽在肺损伤实验模型中的作用]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
L Atzori, A M Corriga, L Congiu
{"title":"[Participation of tachykinins in experimental models of lung damage].","authors":"L Atzori,&nbsp;A M Corriga,&nbsp;L Congiu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present investigation a possible involvement of tachykinins during sulfur dioxide-(SO2) and metabisulfite-(MBS) induced bronchoconstriction, and paraquat (PQ)-induced mortality was studied. SO2 (250ppm) inhalation and MBS (3mM) perfusion induced a marked decrease of compliance and conductance in the isolated and perfused lung. SO2-induced bronchoconstriction was associated with release of Calcitonin Gene Related Peptide, suggesting activation of capsaicin sensitive sensory nerves. Pretreatment of animals with capsaicin, in order to deplete the tachykinin content of sensory nerves, significantly reduced SO2- and MBS-induced bronchoconstriction. PQ (25mg/Kg) treatment induced high mortality (75%) after 3 weeks. Pretreatment with capsaicin significantly protected versus PQ induced mortality (25%). The results suggest that tachykinin content in the respiratory airways participate to SO2- and MBS-induced bronchoconstriction and PQ mortality.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"65-70"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19954102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drinking habits and occupational exposure to xenobiotics: a review. 饮酒习惯和职业暴露于外源性抗生素:综述。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
S Bisio, G Franco
{"title":"Drinking habits and occupational exposure to xenobiotics: a review.","authors":"S Bisio,&nbsp;G Franco","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The evaluation of health status of workers exposed to a variety of chemicals is usually performed by means of several laboratory indices. Our aim is to review literature data in order to evaluate the influence of some lifestyle characteristics (alcohol intake) on these parameters. Since alcohol intake is responsible for a modification of some laboratory parameters in healthy workers, the medical surveillance of workers exposed to chemicals should include a careful evaluation of alcohol intake.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19904506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Medico-legal aspects of the 89/931 act of the EEC]. [89/931号欧共体法案的医疗法律方面]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
G Arcudi, C Bracci, S Mauriello
{"title":"[Medico-legal aspects of the 89/931 act of the EEC].","authors":"G Arcudi,&nbsp;C Bracci,&nbsp;S Mauriello","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The act 391/89 which introduces some substantial news regarding the protection of public welfare and the safety of workers, will be taken in account in a next future. The A.A. examine these innovations and underline the way they will reassert the importance of a concrete application of the principles of primary prevention. Moreover, this act will have a large impact on forensic medicine as it will allow the acquisition of objective elements to asses the casual nexus between occupational exposure and injury, while evaluating the occupational etiology of the damage.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"83-5"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19953272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Protective effect on nephropathy and on cataract in the streptozotocin-diabetic rat of the vanadium-lazaroid combination]. [类钒联用对链脲佐菌素-糖尿病大鼠肾病和白内障的保护作用]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
S Bosia, E Burdino, F Grignolo, G Ugazio
{"title":"[Protective effect on nephropathy and on cataract in the streptozotocin-diabetic rat of the vanadium-lazaroid combination].","authors":"S Bosia,&nbsp;E Burdino,&nbsp;F Grignolo,&nbsp;G Ugazio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Experimental work from our laboratory has confirmed the protective power of vanadium compounds on hyperglycemia and glycosuria in streptozotocin (STZ) diabetes. Furthermore, the diabetic cataract too has been partially prevented. The protection slightly increased, when vanadium was administered in combination with vitamin E. This investigation has introduced a combination of Na3VO4 plus the lazaroid U-83836E, a liposoluble antioxidant much more efficacious than tocopherol, in order to improve the insufficient protection when vitamin E was used. Male Wistar rats, rendered diabetic with STZ, were treated for 12 weeks with Na3VO4 in drinking water, U-83836E carried by the food, or both. The most significant metabolic parameters (food and fluid intake, diuresis and excreted feces) were studied monthly by means of metabolic cages. Body weight, glycemia, glycosuria and proteinuria were also recorded. At week 6 and 12 of the treatment, the opaqueness of the eye lenses was controlled. Circulation glycosylated hemoglobin (HbA1c), fructosamine, N-acetyl-beta-D-glucosaminidase (NAG) and fluorescent peroxides were evaluated at the end of the experiment. After the first month of treatment U-83836E improved significantly the protective effect of vanadate alone on polydipsia and polyuria, but more efficiently on hyperglycemia and glycosuria. The further ameliorating effect of the lazaroid was observed also on HbA1c, NAG and, most important, on the cataract. In conclusion, these findings demonstrate that the lazaroid U-83836E succeeds in further protecting the most important symptoms of diabetes treated with vanadate, and that this antioxidant acts effectively even when it is administered per os, in a non invasive manner.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"71-5"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19954103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Importance of the specific surface area in the study of the biological effects of dusts of industrial use]. [比表面积在工业粉尘生物效应研究中的重要性]。
Giornale italiano di medicina del lavoro Pub Date : 1995-01-01
M Governa, M Valentino, I Visonà, F Monaco, M Amati
{"title":"[Importance of the specific surface area in the study of the biological effects of dusts of industrial use].","authors":"M Governa,&nbsp;M Valentino,&nbsp;I Visonà,&nbsp;F Monaco,&nbsp;M Amati","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have studied a sample of commercial sepiolite and two samples of commercial vermiculite which are advised to replace asbestos, and we have in vitro tested their abilities to activate the complement and to lyse erythrocytes. Their behaviours has been compared with those of asbestos fibres given by Union Internationale Contre le Cancer (UICC) as reference standards. We have first measured the specific surface area and the weight of each mineral. Sepiolite has been inactive in complement activation and little able to lysis red blood cells on the base of surface area; on the base of the weight it has been unreactive in complement activations but very reactive in red blood cells lysis. We believe that in the in vitro assays to evaluate the biological effects of the substitutes of asbestos it is very important to considerate as the weight and as the specific surface are of each clay mineral.</p>","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"17 1-6","pages":"105-9"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19952046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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