[尿路上皮肿瘤和无肿瘤膀胱壁石棉纤维的浓度]。

L Pollice, G M Ferri, L Paoletti, A Gentile, U Iacobellis, D Batisti, P Di Tonno, G Caruso, R Molinini
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引用次数: 0

摘要

我们的研究目的是寻找石棉纤维最终存在于13例膀胱癌的肿瘤组织和12例对照病例的正常膀胱组织中,没有瘤变并因其他泌尿系统疾病而手术。对所有患者进行了标准化问卷调查,以确定最终接触石棉的实体。在原子氧等离子体中低温氧化组织中的有机成分,并用透射电镜和能谱法对残余无机成分进行了分析。在25个检测样本中,我们只在两个样本中发现了石棉纤维;在这两个病例中,他们都属于受肿瘤影响的患者,其中一人也受到肺石棉的影响。我们在这项研究中使用的程序,与我们的其他经验相比,使我们能够降低组织被石棉污染的风险,正如纤维阳性发现的病例数量较少以及阳性病例中纤维浓度较低所表明的那样。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Concentration of asbestos fibers in urothelial tumors and in the neoplasm-free bladder wall].

The aim of our study was to search the eventual presence of asbestos fibers in the neoplastic tissue of 13 cases of bladder carcinoma and in the normal vesical tissue of 12 control cases without neoplasia and operated upon for other urologic pathologies. To all patients a standardised questionnaire has been administered in order to ascertain the entity of the eventual exposition to asbestos. The organic component of the tissues has been oxidated at low temperature in atomic oxygen plasma and the residual inorganic component has been analysed by transmission electronic microscopy and energy dispersion spectrometry. We have found asbestos fibers only in two over the 25 examined samples; in both cases they belonged to patients affected by the neoplasia and in one of them also by pulmonary asbestos. The procedures that we used in this study, in respect to our other experiences, allowed us to reduce the risk of contamination of the tissues by asbestos, as it is shown by the lower number of cases with positive finding of fibers and by lower concentration of fibers in the positive cases.

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