Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics最新文献

Spectrophotometric measurements of haemoglobin saturation and concentration in skin during the tuberculin reaction in normal human subjects. 结核菌素反应期间正常人皮肤血红蛋白饱和度和浓度的分光光度测定。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/005

D K Harrison, S D Evans, N C Abbot, J S Beck, P T McCollum

{"title":"Spectrophotometric measurements of haemoglobin saturation and concentration in skin during the tuberculin reaction in normal human subjects.","authors":"D K Harrison, S D Evans, N C Abbot, J S Beck, P T McCollum","doi":"10.1088/0143-0815/13/4/005","DOIUrl":"https://doi.org/10.1088/0143-0815/13/4/005","url":null,"abstract":"A non-invasive technique employing light-guide spectrophotometry is described for the measurement of haemoglobin concentration and oxygenation in human skin. Measurements were carried out in the visible wavelength range (500-620 nm) and a series of experiments were carried out in vitro and in vivo in order to calibrate the system. Indices were derived for the measurement of relative haemoglobin concentration and absolute oxygen saturation. The technique was applied to measure the changes in these parameters occurring during the course of the tuberculin reaction in human skin. The results are compared with those from laser Doppler flowmetry and transcutaneous oxygen measurements which were carried out concurrently. Divergence between the intracapillary and tissue oxygenation during the course of the reaction provides evidence for the existence of increased diffusion resistance for oxygen; a model is proposed. The study demonstrates the potential clinical usefulness of light-guide spectrophotometry for the non-invasive investigation of tissue oxygen supply.","PeriodicalId":77070,"journal":{"name":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","volume":"13 4","pages":"349-63"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/0143-0815/13/4/005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12653276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 80

An error study on some linear reconstruction algorithms for electrical impedance tomography. 电阻抗层析成像中几种线性重建算法的误差研究。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/007

Z Q Chen, F J Paoloni

引用次数: 3

Flow measurement using duplex Doppler ultrasound: haemodynamic changes in patients with colorectal liver metastases. 双多普勒超声血流测量:结直肠肝转移患者血流动力学变化。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/001

J Robertson, E Leen, J A Goldberg, W J Angerson, G R Sutherland, C S McArdle

{"title":"Flow measurement using duplex Doppler ultrasound: haemodynamic changes in patients with colorectal liver metastases.","authors":"J Robertson, E Leen, J A Goldberg, W J Angerson, G R Sutherland, C S McArdle","doi":"10.1088/0143-0815/13/4/001","DOIUrl":"https://doi.org/10.1088/0143-0815/13/4/001","url":null,"abstract":"Duplex Doppler ultrasound has been used to make measurements of liver blood flow. The relationship between time average velocity as measured using pulsed Doppler and the true mean velocity was determined using a flow phantom. Correction factors were applied to measured time average velocities of blood in the hepatic artery and portal vein. Blood flow was calculated from the product of corrected velocities and the cross-sectional area of the vessels. There was no significant difference in total liver blood flow for patients with colorectal liver metastases when compared with controls. However, the ratio of the hepatic arterial flow to the sum of the portal and hepatic arterial flows (Doppler perfusion index, DPI) was markedly elevated (P < 0.0001) in the patients with metastases when compared with the controls. The DPI values for a third group of subjects who had undergone resection for colonic cancer but who had no proven liver metastases overlapped the values for the other two groups. When attention is paid to technique, the procedure can detect and quantify the changes in liver blood flow which occur in the presence of metastases.","PeriodicalId":77070,"journal":{"name":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","volume":"13 4","pages":"299-310"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/0143-0815/13/4/001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12653273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Effects of myocardial electrotonic interaction on the sequence of excitation and repolarisation and on T wave polarity. Computer modelling experiments. 心肌电紧张相互作用对兴奋和复极顺序及T波极性的影响。计算机模拟实验。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/006

M Malik, A J Camm

{"title":"Effects of myocardial electrotonic interaction on the sequence of excitation and repolarisation and on T wave polarity. Computer modelling experiments.","authors":"M Malik, A J Camm","doi":"10.1088/0143-0815/13/4/006","DOIUrl":"https://doi.org/10.1088/0143-0815/13/4/006","url":null,"abstract":"A computer model of a 3-dimensional rectangular block of myocardial tissue (3969 cells) has been used to investigate the influence on excitation and repolarisation sequences and on the modelled electrocardiographic T wave of (a) electrotonic interaction, (b) intrinsic distribution of refractoriness, and (c) the speed of repolarisation of action potentials. The model allowed electrotonic interactions to be investigated separately during the depolarisation and repolarisation phases. Scales of 14 values of the strength of electrotonic interaction during the depolarisation phase, 14 values of the strength of electrotonic interaction during the repolarisation phase, 3 shapes of action potential, and 5 distributions of tissue refractoriness were selected and all 2940 combinations were examined. In each experiment, the tissue model was artificially excited and the resulting excitation and repolarisation sequences were simulated. The results of the study suggested that electrotonic interactions between excited cells can cause non-uniform speed of propagation which, by means of the phase shifts of action potentials, contributes to the inversion of the repolarisation sequence and to the physiologic orientation of T waves. Experiments with this model did not support the hypothesis that simple electrotonic smoothing of the differences in repolarisation phases due to the excitation phase shift of action potentials reverses the repolarisation sequence and explains T wave polarity.","PeriodicalId":77070,"journal":{"name":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","volume":"13 4","pages":"365-87"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/0143-0815/13/4/006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12653277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement of surgical diathermy current during trans-urethral resection of the prostate gland. 经尿道前列腺切除术中外科透热电流的测量。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/003

P D Hill, A G Timoney, W S Ng

{"title":"Measurement of surgical diathermy current during trans-urethral resection of the prostate gland.","authors":"P D Hill, A G Timoney, W S Ng","doi":"10.1088/0143-0815/13/4/003","DOIUrl":"https://doi.org/10.1088/0143-0815/13/4/003","url":null,"abstract":"A system is described that has been developed to measure the surgical diathermy current passing through the patient during each cut of a trans-urethral resection of the prostate gland (TURP), with 1.5% glycine solution as irrigant. The immediate aim was to distinguish capsular tissue of the male prostate gland from the hyperplastic adenomatous tissue within it. The ultimate aim was to prevent resection into the surgical capsule which can easily result in excessive blood loss and absorption of irrigant. The system was used in a conventional theatre setting with a commercial diathermy system (Eschmann TD 411-S) of known output characteristics. Measurements were made in 12 patients during resection with a standard loop, involving typically 75 cuts in each patient (60 in adenoma and 15 in capsule). In 8 of these patients this was followed by roller ball placement on typically 10 sites each of capsule or residual adenoma at very low diathermy settings. The results showed great variability both between patients, and between different cuts in the same patient, with no consistent difference between tissues identified under direct vision as adenoma and surgical capsule. Physical reasons are suggested for the observed variability, and it is concluded that it is not possible to use this technique to guide tissue resection in the prostate.","PeriodicalId":77070,"journal":{"name":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","volume":"13 4","pages":"323-34"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/0143-0815/13/4/003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12457352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimony electrode for the determination of the intramyocardial pH during open-heart surgery. 心内直视手术中测定心内pH值的锑电极。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/004

Y Ota, M Tsunemoto, M Shimada

{"title":"Antimony electrode for the determination of the intramyocardial pH during open-heart surgery.","authors":"Y Ota, M Tsunemoto, M Shimada","doi":"10.1088/0143-0815/13/4/004","DOIUrl":"https://doi.org/10.1088/0143-0815/13/4/004","url":null,"abstract":"The development of an antiomony electrode (Sb) and a pH meter as a substitute for a glass electrode(G) to measure the intramyocardial pH is reported, and the results of their clinical application. The determination of the pH of CPD (citrate-phosphate-dextrose) blood by Sb showed small differences when compared to G (less than 0.1). Sb was also temperature sensitive. The temperature coefficient of Sb was determined in buffers by varying their temperatures, and an antimony-thermocouple electrode and a temperature-compensated pH meter were subsequently constructed. In CPD blood of varying temperatures Sb showed similar tendencies to G. The results of the application of the new apparatus to 28 patients were statistically no different from those obtained previously by G on 22 patients, either in baseline pH or its fall following aortic cross-clamping. It is concluded that although Sb is not as accurate as G, it is a reasonable alternative for the determination of myocardial acidosis during open-heart surgery.","PeriodicalId":77070,"journal":{"name":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","volume":"13 4","pages":"335-47"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/0143-0815/13/4/004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12653275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Changes of erythropoietic and storage iron components in certain clinical situations as evaluated by ferrokinetic investigations. 铁动力学研究评价某些临床情况下红细胞生成和储存铁成分的变化。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/008

M M Gupta, P Roth, E Werner

{"title":"Changes of erythropoietic and storage iron components in certain clinical situations as evaluated by ferrokinetic investigations.","authors":"M M Gupta, P Roth, E Werner","doi":"10.1088/0143-0815/13/4/008","DOIUrl":"https://doi.org/10.1088/0143-0815/13/4/008","url":null,"abstract":"A method is described for the quantitative analysis of in vivo organ measurements of 59Fe activity in ferrokinetic investigations. The time-activity curves obtained by sequential surface monitoring over sacrum, liver and spleen can be resolved quantitatively into their different components contributing to the recorded count rate. The analysis is performed in three steps: (1) Count rate contributions from activity in other organs and from scattered radiation from regions outside the organ under investigation are corrected. (2) Distinction is made between radioactivity uptake of the tissue and radioactivity contained in the perfusing blood. (3) The resulting net organ activity is then further resolved into an erythropoietic and a storage iron component by use of a computer program (SAAM-27) and assuming a compartmental model for internal iron exchange. The method was tested in three groups of patients with different haematological disorders and in normal controls. Characteristic patterns of the parameters are found for different diseases and the results correlated well with the clinical findings. It is concluded that in vivo organ measurements of 59Fe activity, when performed and analysed with sufficient care, can provide an insight into the dynamics of the iron exchange that is taking place in an organ. This analytical approach may improve the diagnostic predictions of ferrokinetic investigations.","PeriodicalId":77070,"journal":{"name":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","volume":"13 4","pages":"411-8"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/0143-0815/13/4/008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12653279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A thermal clearance probe for continuous monitoring of cerebral blood flow. 用于连续监测脑血流的热清除探头。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-11-01 DOI: 10.1088/0143-0815/13/4/002

I R Chambers, M S Choksey, A Clark, A Green, A Jenkins, A D Mendelow

引用次数: 3

Non-invasive determination of systolic blood pressure by heart sound pattern analysis. 心音模式分析无创测定收缩压。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-08-01 DOI: 10.1088/0143-0815/13/3/004

A Bartels, D Harder

引用次数: 32

Mechanical parameters of human hair: possible application in the diagnosis and follow-up of hair disorders. 人类头发的力学参数:在头发疾病的诊断和随访中的可能应用。

Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics Pub Date : 1992-08-01 DOI: 10.1088/0143-0815/13/3/008

G Nikiforidis, C Balas, D Tsambaos

引用次数: 15