American Journal of Cardiology最新文献

{"title":"Erratum to “Cardiac screening findings and referral patterns in male African-American basketball players: Analysis of the HeartBytes Registry”[The American Journal of Cardiology 243 (2025) 73-80]","authors":"Douglas Corsi MD , Avinash Saraiya BS , Maggie Doyle BS , Vacha Shah BS , Blaise O’Malley MPH , Grace Qiu BS , Renee Lanstaff PA-A , Imran Masood DO , Brian Osler MD , Alexander G. Hajduczok MD , Drew Johnson MD , David Shipon MD","doi":"10.1016/j.amjcard.2025.08.015","DOIUrl":"10.1016/j.amjcard.2025.08.015","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":"255 ","pages":"Page 109"},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Stratifying Acute Total Occlusions in Non-ST-Segment Elevation Myocardial Infarction: Time for a Modified GRACE Score?","authors":"S Elissa Altin, Jennifer Miao","doi":"10.1016/j.amjcard.2025.08.053","DOIUrl":"10.1016/j.amjcard.2025.08.053","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventricular Assist Devices in Patients With Transposition of the Great Arteries.","authors":"S Sekhon, B Cheema, S Argaw, T Wu, R Harap, F S Ahmed, K Ghafourian, M Monge, A Pawale, D T Pham, Y Raza, A Tibrewala, J D Rich, E Vorovich, J Wilcox, Q R Youmans, I S Okwuosa","doi":"10.1016/j.amjcard.2025.09.001","DOIUrl":"10.1016/j.amjcard.2025.09.001","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climbing to the Summit of Guideline Directed Therapy of Heart Failure:A Slippery Slope.","authors":"James L Vacek","doi":"10.1016/j.amjcard.2025.09.002","DOIUrl":"10.1016/j.amjcard.2025.09.002","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Magnesium Bioresorbable Stent May Yet Prevail.","authors":"Harris Majeed, James Blankenship","doi":"10.1016/j.amjcard.2025.08.058","DOIUrl":"10.1016/j.amjcard.2025.08.058","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug Coated Balloons vs Drug Eluting Stents in Elderly Patients: What Matters Most, the Question or the Answer?","authors":"Carlo Briguori, Luca Paolucci","doi":"10.1016/j.amjcard.2025.08.056","DOIUrl":"10.1016/j.amjcard.2025.08.056","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Principles of Coronary Sinus Narrowing to Relieve Myocardial Ischemia and Improve Angina.","authors":"Megha Prasad, Maayan Konigstein, Ranil de-Silva, Amir Lerman, Shmuel Banai","doi":"10.1016/j.amjcard.2025.08.066","DOIUrl":"10.1016/j.amjcard.2025.08.066","url":null,"abstract":"<p><p>Effective therapy for patients suffering from refractory angina remains a major unmet need. Chronic angina, which is refractory to medical and interventional therapies, affects patients who are not suitable for revascularization, patients following successful revascularization, and patients with coronary microvascular dysfunction. Coronary sinus (CS) narrowing has been studied as a potential therapy for patients with angina. Pre-clinical and clinical data, including 2 randomized sham-controlled clinical trials and 2 large prospective multi-center registries, have confirmed the safety and effectiveness of CS narrowing in patients with refractory angina due to obstructive coronary artery disease (CAD). Preliminary pathophysiologic studies suggest that CS narrowing may also improve coronary microvascular function and alleviate microvascular angina. Here, we review the historical perspective, mechanism of action, and clinical applications of CS narrowing. In Conclusion: With the accumulation of new data, the time is ripe to revisit the therapeutic benefits seen in historical CS interventions and demonstrated in recent clinical research to reduce angina and ischemia and improve quality of life of patients with disabling refractory angina.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"128-133"},"PeriodicalIF":2.1,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking Myocardial Bridge-Related Ischemia by Quantitative Flow Ratio Functional Evaluation.","authors":"Francesco Cardaioli, Tommaso Sciarretta, Federico Arturi, Tommaso Fabris, Giulia Masiero, Massimo Napodano, Chiara Fraccaro, Andrea Panza, Luca Nai Fovino, Giuseppe Tarantini","doi":"10.1016/j.amjcard.2025.08.062","DOIUrl":"10.1016/j.amjcard.2025.08.062","url":null,"abstract":"<p><p>A myocardial bridge (MB) is a condition where a segment of an epicardial coronary artery passes through the myocardial muscle. While traditionally regarded as benign, MBs have been associated with various cardiovascular conditions. Therefore, assessing their hemodynamic impact is crucial for informed treatment decisions. Intracoronary functional assessments, such as fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR), have proven useful, especially under inotropic stimulation. However, their invasive nature limits their widespread clinical application. The Quantitative Flow Ratio (QFR) has emerged as a minimally invasive alternative for functional evaluation of MBs, though data on its use are still limited. This study aims to compare the diagnostic efficacy of FFR, iFR, and QFR for evaluating MBs both at rest and under stress conditions. Patients with confirmed MB on the LAD and typical angina (or abnormal noninvasive tests indicating myocardial ischemia) were included. According to a prespecified protocol, all patients underwent functional intracoronary evaluation with FFR and iFR at rest and after dobutamine and atropine intravenous infusion. QFR was also calculated for all cases both at rest and during dobutamine infusion. FFR values ≤0.80, iFR values ≤0.89 and QFR values ≤0.84 were considered indicative of significant myocardial ischemia. A total of 21 patients were included. Median FFR remained unchanged from rest (0.85) to stress (0.85), with only 1 patient showing a positive stress-FFR. In contrast, median iFR significantly decreased from 0.91 to 0.79 (p <0.001), with stress-iFR ≤0.89 in 18 patients. Resting QFR did not indicate significant hemodynamic impact of the MB (median 0.90), but under inotropic stimulation, ischemia was detected in 18 patients (median 0.79, p <0.001). QFR and iFR were concordant during stress in 19 patients, showing a significant positive correlation (Spearman's ρ = 0.702, p = 0.037) and comparable sensitivity (0.86). QFR, computed during inotropic infusion, shows high sensitivity for detecting MB-related ischemia, comparable to stress-iFR and superior to stress-FFR. The correlation between stress-induced iFR and QFR suggests QFR as a reliable, minimally invasive alternative for functional lesion-specific evaluation in MB patients. Larger studies are necessary to confirm these preliminary findings and standardize QFR use in dynamic coronary stenosis assessments.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"112-118"},"PeriodicalIF":2.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Ostial Left Anterior Descending Coronary Artery Lesions: to Cross or not to Cross.","authors":"Fernando Alfonso, Manuel Pan, Héctor M García-García","doi":"10.1016/j.amjcard.2025.08.057","DOIUrl":"10.1016/j.amjcard.2025.08.057","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction of Risk of Death and Improvement in Functional Capacity After Cardiac Rehabilitation on Heart Failure Prognosis","authors":"Domenico Scrutinio ,&nbsp;Pietro Guida ,&nbsp;Andrea Passantino","doi":"10.1016/j.amjcard.2025.08.054","DOIUrl":"10.1016/j.amjcard.2025.08.054","url":null,"abstract":"<div><div>Whether risk of death interacts with change in 6-minute walking test (6MWT) distance after cardiac rehabilitation (CR) on heart failure (HF) prognosis is unknown. We studied 1,569 patients with HF admitted to 6 inpatient CR units. A 6MWT was performed at admission to and at discharge from CR. The primary outcome was 3-year mortality. The interaction of baseline risk and 50-meter increase in 6MWT distance on the primary outcome was tested using a Cox regression model with an interaction term between baseline risk and 50-meter increase. To further illustrate the interaction between baseline risk and change in 6MWT distance, participants were stratified into low- and high-risk subgroups. The p value for the interaction was 0.588. Three-year mortality was 16.1% in the low-risk and 53.7% in the high-risk subgroup. 43.0% of the low-risk and 43.4% of the high-risk patients achieved an increase ≥50 meters in 6MWT distance. The adjusted hazard ratio of 3-year mortality for the patients who achieved a 50-meter increase in 6MWT distance was 0.67 (0.47–0.96; p = 0.030) in the low-risk and 0.75 (0.61–0.91; p = 0.005) in the high-risk subgroup. These findings suggest that improvement in functional capacity after CR is associated with improved survival regardless of baseline risk of death.</div></div>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":"258 ","pages":"Pages 41-48"},"PeriodicalIF":2.1,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}