American Journal of Cardiology最新文献

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Abbreviated Duke Activity Status Index for Risk Stratification in Heart Failure. 用于心力衰竭风险分层的缩写杜克活动状态指数:缩写杜克活动状态指数。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-26 DOI: 10.1016/j.amjcard.2024.11.029
Silvio Nunes Augusto, Yuping Wu, Thanat Chaikijurajai, Stanley L Hazen, W H Wilson Tang
{"title":"Abbreviated Duke Activity Status Index for Risk Stratification in Heart Failure.","authors":"Silvio Nunes Augusto, Yuping Wu, Thanat Chaikijurajai, Stanley L Hazen, W H Wilson Tang","doi":"10.1016/j.amjcard.2024.11.029","DOIUrl":"10.1016/j.amjcard.2024.11.029","url":null,"abstract":"<p><p>The Duke activity status index (DASI), a self-administered 12-item questionnaire has been used to estimate functional capacity and recently demonstrated prognostic information. We aimed to develop an abbreviated version for clinical applications. Leveraging the Cleveland Clinic GeneBank Study, we developed an abbreviated DASI questionnaire (aDASI) with the machine learning XGBoost algorithm, with the goal of maintaining the accuracy and reliability of the original DASI. We validated the prognostic value of aDASI in a subset of patients with heart failure from GeneBank and an independent data set from the GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure; ClinicalTrials.gov NCT01685840) trial. The results confirmed the congruence and accuracy between the original and the abbreviated scores while reducing the number of questions (R = 0.97, p <0.001). The original DASI score and the aDASI exhibited a strong correlation in the GeneBank and predictive value for all-cause mortality at different time points in the GUIDE-IT cohort. In conclusion, the abbreviated DASI tracks with original DASI assessment and performs comparably to the original DASI questionnaire in predicting all-cause mortality.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"54-59"},"PeriodicalIF":2.3,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Detection Rate of Late Gadolinium Enhancement in Takotsubo Syndrome: A Systematic Review and Meta-Analysis.
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-26 DOI: 10.1016/j.amjcard.2024.11.017
Luca Fazzini, Matteo Casula, Riccardo Cau, Marta Figueiral, Matteo Castrichini, Giulio Binaghi, Marco Corda, Naveen L Pereira, Luca Saba, Roberta Montisci, Abhiram Prasad
{"title":"The Detection Rate of Late Gadolinium Enhancement in Takotsubo Syndrome: A Systematic Review and Meta-Analysis.","authors":"Luca Fazzini, Matteo Casula, Riccardo Cau, Marta Figueiral, Matteo Castrichini, Giulio Binaghi, Marco Corda, Naveen L Pereira, Luca Saba, Roberta Montisci, Abhiram Prasad","doi":"10.1016/j.amjcard.2024.11.017","DOIUrl":"10.1016/j.amjcard.2024.11.017","url":null,"abstract":"<p><p>The absence of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) is commonly used to distinguish takotsubo syndrome (TTS) from other myocardial diseases. However, case series have reported the presence of LGE in TTS. This study aimed to summarize the evidence on the frequency of LGE in TTS and identify potential variables that may influence the detection of LGE. Electronic databases were systematically searched for studies reporting LGE frequency in patients with TTS. The overall frequency was estimated using the inverse variance method and a random-effects model for a single proportion. Factors influencing LGE detection were analyzed. Of 490 studies screened, 21 were included (703 patients, 90% women). The estimated overall frequency of LGE was 22.4% (95% confidence interval [CI] 8.7% to 39.6%). In patients with TTS who underwent CMR within 3 days of symptom occurrence, the frequency of LGE was 40.7% (95% CI 18.8% to 64.5%), which was significantly higher than in those who performed CMR after 3 days (3.9%, p <0.010). The sensitivity threshold used in the imaging protocols had a statistically significant impact on the frequency of LGE detection (p = 0.030). A total of 10 studies performed a follow-up CMR after at least 3 months, reporting a frequency of LGE of 1.7% (95% CI 0.0% to 8.9%). In conclusion, published studies report the presence of LGE in TTS at presentation in a significant proportion of patients. However, its detection is strongly influenced by the duration between symptom onset and CMR acquisition and by the sensitivity threshold used for the imaging protocol. LGE is rarely present at follow-up.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct Oral Anticoagulants Versus Warfarin for the Treatment of Left Ventricular Thrombus: A Multicenter Retrospective Observational Study. 治疗左心室血栓的直接口服抗凝剂与华法林:一项多中心回顾性观察研究。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-24 DOI: 10.1016/j.amjcard.2024.11.026
Abdullah Al-Abcha, Shannon Clay, Ling Wang, Rohan Madhu Prasad, Mohammad Fahad Salam, Shaurya Srivastava, Manel Boumegouas, George S Abela, Yehia Saleh, Essa M Essa
{"title":"Direct Oral Anticoagulants Versus Warfarin for the Treatment of Left Ventricular Thrombus: A Multicenter Retrospective Observational Study.","authors":"Abdullah Al-Abcha, Shannon Clay, Ling Wang, Rohan Madhu Prasad, Mohammad Fahad Salam, Shaurya Srivastava, Manel Boumegouas, George S Abela, Yehia Saleh, Essa M Essa","doi":"10.1016/j.amjcard.2024.11.026","DOIUrl":"10.1016/j.amjcard.2024.11.026","url":null,"abstract":"<p><p>Vitamin K antagonists remain the mainstay of therapy in patients with left ventricular thrombus (LVT) because the efficacy of direct oral anticoagulants (DOACs) is not well-established. We performed a multicenter retrospective analysis of adults admitted between January 2015 and December 2021 and diagnosed with LVT to compare the safety and efficacy of warfarin versus DOACs. The primary outcome was thrombus resolution. Secondary outcomes included all-cause mortality, bleeding events, and stroke or systemic embolism. A total of 189 patients were included. The rate of thrombus resolution was similar in patients with LVT treated with DOACs compared with those treated with warfarin (DOACs 73.9%vs warfarin 68.5%, p = 0.489). In addition, all-cause mortality (DOACs 13.04% vs warfarin 9.79%, p = 0.583), bleeding events (DOACs 19.57% vs warfarin 13.99%, p = 0.361), and stroke or systemic embolism (DOACs 10.87% vs warfarin 15.38%, p = 0.446) were all similar in the 2 groups. In the propensity-matched group, 90 patients were included. Multivariate analysis showed no significant difference of using warfarin or DOACs on thrombus resolution (odds ratio [OR] 0.94, 95% confidence interval [CI] 0.858 to 1.029, p = 0.18), all-cause mortality (OR 1.032, 95% CI 0.906 to 1.176, p = 0.6354), bleeding events (OR 1.694, 95% CI 0.168 to 17.097, p = 0.655), or stroke or systemic embolism (OR 1.947, 95% CI 0.087 to 4.756, p = 0.6747). In conclusion, in our retrospective analysis, DOACs had similar efficacy and safety compared with warfarin in the treatment of LVT.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"21-24"},"PeriodicalIF":2.3,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invasive Coronary Angiography Versus Noninvasive Computed Tomography Coronary Angiography as Preoperative Coronary Imaging for Valve Surgery. 有创冠状动脉造影与无创 CT 冠状动脉造影作为瓣膜手术术前冠状动脉成像的对比。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-23 DOI: 10.1016/j.amjcard.2024.11.015
Tulio Caldonazo, Hristo Kirov, Ivan Dochev, Johannes Fischer, Angelique Runkel, Marc Dewey, Rhanderson Cardoso, Ulf Teichgräber, Murat Mukharyamov, Stephanie Gräger, Torsten Doenst
{"title":"Invasive Coronary Angiography Versus Noninvasive Computed Tomography Coronary Angiography as Preoperative Coronary Imaging for Valve Surgery.","authors":"Tulio Caldonazo, Hristo Kirov, Ivan Dochev, Johannes Fischer, Angelique Runkel, Marc Dewey, Rhanderson Cardoso, Ulf Teichgräber, Murat Mukharyamov, Stephanie Gräger, Torsten Doenst","doi":"10.1016/j.amjcard.2024.11.015","DOIUrl":"10.1016/j.amjcard.2024.11.015","url":null,"abstract":"<p><p>Coronary computed tomography angiography (CCTA) has emerged as a noninvasive alternative to invasive coronary angiography (ICA) for diagnosing coronary artery disease (CAD). Hence, the question of CCTA's ability to guide surgical decision-making moves into the center of attention. CCTA is specifically powerful in ruling out CAD. We, therefore, performed a meta-analysis and systematic review to compare the clinical end points between patients who received ICA or CCTA to rule out CAD before valve surgery. A total of 3 databases were assessed. The primary outcome was perioperative mortality. Secondary outcomes were acute kidney injury (AKI), myocardial infarction (MI), stroke, and major adverse cardiovascular events (MACEs). The odds ratio (OR) and the respective confidence interval (CI) was calculated. A random-effects model was performed. A total of 5 studies with 6,654 patients qualified for the analysis. There was no significant difference between the 2 groups regarding the primary end point (OR 1.20, 95% CI 0.67 to 2.15, p = 0.53). The secondary outcomes also did not show any significant differences in AKI (OR 1.14, 95% CI 1.14, 0.88 to 1.49, p = 0.32), MI (OR 0.89, 95% CI 0.65 to 1.22, p = 0.45), stroke (OR 1.12, 95% CI 0.48 to 2.60, p = 0.79), or MACEs (OR 1.17, 95% CI 0.86 to 1.59, p = 0.33) incidences. The analysis suggests that CCTA is a safe and reliable noninvasive alternative to ICA for coronary imaging before valve surgery. Conceivable differences in imaging modalities were not associated with increases in perioperative mortality, AKI, MI, stroke, or MACEs.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"1-5"},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Angiography-Derived Fractional Flow Reserve: Newer Data and Future Directions. 血管造影得出的分流量储备:最新数据与未来方向
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-23 DOI: 10.1016/j.amjcard.2024.11.021
Dimitrios Strepkos, Jaskanwal Deep Singh Sara, Pedro E P Carvalho, Michaella Alexandrou, Deniz Mutlu, Ozgur S Ser, Arnold H Seto, William F Fearon, Bavana V Rangan, Olga C Mastrodemos, Sandeep Jalli, Konstantinos Voudris, M Nicholas Burke, Yader Sandoval, Emmanouil S Brilakis
{"title":"Angiography-Derived Fractional Flow Reserve: Newer Data and Future Directions.","authors":"Dimitrios Strepkos, Jaskanwal Deep Singh Sara, Pedro E P Carvalho, Michaella Alexandrou, Deniz Mutlu, Ozgur S Ser, Arnold H Seto, William F Fearon, Bavana V Rangan, Olga C Mastrodemos, Sandeep Jalli, Konstantinos Voudris, M Nicholas Burke, Yader Sandoval, Emmanouil S Brilakis","doi":"10.1016/j.amjcard.2024.11.021","DOIUrl":"10.1016/j.amjcard.2024.11.021","url":null,"abstract":"<p><p>Several novel software systems have been developed for the reconstruction of the coronary artery tree and the calculation of fractional flow reserve (FFR) from coronary artery angiography images without coronary artery instrumentation: FFR<sub>angio</sub>, Computational pressure-flow dynamics derived FFR, quantitative flow ratio (QFR), and vessel FFR. In this report, we review the current evidence on each software, their contemporary use, and future directions.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"1-8"},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142708962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of Aortic Arch Tears Using Epiaortic Ultrasound During Surgical Management of Acute Type A Aortic Dissection. 在手术治疗急性 A 型主动脉夹层期间使用主动脉外膜超声检测主动脉弓撕裂。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-23 DOI: 10.1016/j.amjcard.2024.11.020
Taylor Pickering, Kyle McCullough, Cody Dorton, Emily Shih, Austin Kluis, Jasjit Banwait, Swapnil Gupta, Madhura Kapil Shah, Julius Ejiofor, William Brinkman, Justin Schaffer, J Michael DiMaio, Katherine Harrington, Lee Hafen
{"title":"Detection of Aortic Arch Tears Using Epiaortic Ultrasound During Surgical Management of Acute Type A Aortic Dissection.","authors":"Taylor Pickering, Kyle McCullough, Cody Dorton, Emily Shih, Austin Kluis, Jasjit Banwait, Swapnil Gupta, Madhura Kapil Shah, Julius Ejiofor, William Brinkman, Justin Schaffer, J Michael DiMaio, Katherine Harrington, Lee Hafen","doi":"10.1016/j.amjcard.2024.11.020","DOIUrl":"10.1016/j.amjcard.2024.11.020","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"14-16"},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Effectiveness of On-Pump Versus Off-Pump Coronary Surgical Revascularization Related to Postoperative Acute Kidney Injury. 与术后急性肾损伤相关的冠状动脉外科血管重建术(On-Pump)与非Off-Pump的疗效比较。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-23 DOI: 10.1016/j.amjcard.2024.11.016
Santhosh K G Koshy, Ajit K Tharakan, Lekha K George, Gregory F Petroski, Martin H Gregory, Jamie B Smith, Taha Mansoor, Robin L Kruse
{"title":"Comparative Effectiveness of On-Pump Versus Off-Pump Coronary Surgical Revascularization Related to Postoperative Acute Kidney Injury.","authors":"Santhosh K G Koshy, Ajit K Tharakan, Lekha K George, Gregory F Petroski, Martin H Gregory, Jamie B Smith, Taha Mansoor, Robin L Kruse","doi":"10.1016/j.amjcard.2024.11.016","DOIUrl":"10.1016/j.amjcard.2024.11.016","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"9-11"},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Multicenter Evaluation of the Impact of Therapies on Deep Learning-Based Electrocardiographic Hypertrophic Cardiomyopathy Markers. 多中心评估疗法对基于深度学习的心电图肥厚型心肌病标志物的影响。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-23 DOI: 10.1016/j.amjcard.2024.11.028
Lovedeep S Dhingra, Veer Sangha, Arya Aminorroaya, Robyn Bryde, Andrew Gaballa, Adel H Ali, Nandini Mehra, Harlan M Krumholz, Sounok Sen, Christopher M Kramer, Matthew W Martinez, Milind Y Desai, Evangelos K Oikonomou, Rohan Khera
{"title":"A Multicenter Evaluation of the Impact of Therapies on Deep Learning-Based Electrocardiographic Hypertrophic Cardiomyopathy Markers.","authors":"Lovedeep S Dhingra, Veer Sangha, Arya Aminorroaya, Robyn Bryde, Andrew Gaballa, Adel H Ali, Nandini Mehra, Harlan M Krumholz, Sounok Sen, Christopher M Kramer, Matthew W Martinez, Milind Y Desai, Evangelos K Oikonomou, Rohan Khera","doi":"10.1016/j.amjcard.2024.11.028","DOIUrl":"10.1016/j.amjcard.2024.11.028","url":null,"abstract":"<p><p>Artificial intelligence-enhanced electrocardiography (AI-ECG) can identify hypertrophic cardiomyopathy (HCM) on 12-lead ECGs and offers a novel way to monitor treatment response. Although the surgical or percutaneous reduction of the interventricular septum (SRT) represented initial HCM therapies, mavacamten offers an oral alternative. We aimed to assess the use of AI-ECG as a strategy to evaluate biologic responses to SRT and mavacamten. We applied an AI-ECG model for HCM detection to electrocardiography images from patients who underwent SRT across 3 sites: Yale New Haven Health System (YNHHS), Cleveland Clinic Foundation (CCF), and Atlantic Health System (AHS) and to electrocardiography images from patients receiving mavacamten at YNHHS. A total of 70 patients underwent SRT at YNHHS, 100 at CCF, and 145 at AHS. At YNHHS, there was no significant change in the AI-ECG HCM score before versus after SRT (before SRT: median 0.55 [interquartile range 0.24 to 0.77] vs after SRT: 0.59 [0.40 to 0.75]). The AI-ECG HCM scores also did not improve after SRT at CCF (0.61 [0.32 to 0.79] vs 0.69 [0.52 to 0.79]) and AHS (0.52 [0.35 to 0.69] vs 0.61 [0.49 to 0.70]). Of the 36 YNHHS patients on mavacamten therapy, the median AI-ECG score before starting mavacamten was 0.41 (0.22 to 0.77), which decreased significantly to 0.28 (0.11 to 0.50, p <0.001 by Wilcoxon signed-rank test) at the end of a median follow-up period of 237 days. In conclusion, we observed a lack of improvement in AI-based HCM score with SRT, in contrast to a significant decrease with mavacamten. Our approach suggests the potential role of AI-ECG for serial point-of-care monitoring of pathophysiologic improvement after medical therapy in HCM using ECG images.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"35-40"},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142708960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Prognostic Impact of Diabetes in Takotsubo Syndrome: Insights from the Tokyo Cardiovascular Care Unit Network Registry. 糖尿病在 Takotsubo 综合征中的患病率和预后影响:来自东京心血管护理单位网络登记的启示。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-23 DOI: 10.1016/j.amjcard.2024.11.022
Yukihiro Watanabe, Tsutomu Yoshikawa, Kenshiro Arao, Toshiaki Isogai, Tetsuo Yamaguchi, Toru Egashira, Yoichi Imori, Hiroki Mochizuki, Takeshi Yamamoto, Kuniya Asai, Shun Kohsaka, Morimasa Takayama
{"title":"Prevalence and Prognostic Impact of Diabetes in Takotsubo Syndrome: Insights from the Tokyo Cardiovascular Care Unit Network Registry.","authors":"Yukihiro Watanabe, Tsutomu Yoshikawa, Kenshiro Arao, Toshiaki Isogai, Tetsuo Yamaguchi, Toru Egashira, Yoichi Imori, Hiroki Mochizuki, Takeshi Yamamoto, Kuniya Asai, Shun Kohsaka, Morimasa Takayama","doi":"10.1016/j.amjcard.2024.11.022","DOIUrl":"10.1016/j.amjcard.2024.11.022","url":null,"abstract":"<p><p>Diabetes is a major risk factor for cardiovascular diseases. However, some reports have shown that diabetes has a low prevalence and is associated with favorable outcomes in takotsubo syndrome (TTS). This phenomenon, known as the \"diabetes paradox,\" in which diabetes plays a protective role in the development of TTS, remains controversial. Therefore, we investigated the prevalence of diabetes and the prognostic impact of diabetes and glycemic control in patients with TTS. Using the Tokyo Cardiovascular Care Unit Network registry between 2015 and 2021, we identified 1,226 eligible patients with TTS (median age 77 years, male proportion 21%). The prevalence of diabetes, its clinical characteristics, and its association with in-hospital mortality were assessed. The prevalence of diabetes was 17.0% in TTS and 15.8% in the general population, with no significant difference (p = 0.445). Patients with diabetes were older and had higher body mass index, brain natriuretic peptide, and C-reactive protein levels than patients without diabetes. Patients with diabetes tended to have a higher in-hospital mortality rate than those without (6.3% vs 3.4%, p = 0.057). The multivariable analysis revealed that neither diabetes (odds ratio 1.83, 95% confidence interval 0.88 to 3.80, p = 0.106) nor hemoglobin A1c level was significantly associated with in-hospital mortality. In conclusion, diabetes is not uncommon and not a good prognostic factor in this multicenter registry. Our observations do not support a protective effect of diabetes on the emergence and outcomes of TTS.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"29-34"},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Results of Transcatheter Intervention of Coarctation of the Aorta: A 12-Year Single-Center Experience. 主动脉粥样硬化经导管介入治疗的长期结果:12 年单中心经验。
IF 2.3 3区 医学
American Journal of Cardiology Pub Date : 2024-11-23 DOI: 10.1016/j.amjcard.2024.11.027
Ruitao Li, Qiao Li, Xiang Li, Yijian Li, Zhicheng Chen, Qianbei He, Zhen-Gang Zhao, Yuan Feng
{"title":"Long-Term Results of Transcatheter Intervention of Coarctation of the Aorta: A 12-Year Single-Center Experience.","authors":"Ruitao Li, Qiao Li, Xiang Li, Yijian Li, Zhicheng Chen, Qianbei He, Zhen-Gang Zhao, Yuan Feng","doi":"10.1016/j.amjcard.2024.11.027","DOIUrl":"10.1016/j.amjcard.2024.11.027","url":null,"abstract":"<p><p>Stent implantation has become the treatment of choice in patients with coarctation of the aorta (CoA). However, long-term results are limited. We sought to evaluate the long-term results after CoA intervention based on a 12-year experience. This study aimed to evaluate the long-term outcomes of CoA patients after transcatheter intervention and our innovative techniques. All patients who underwent transcatheter intervention of CoA at our institution between January 2010 and October 2022 were included. Clinical and echocardiographic follow-ups were carried out. A total of 103 patients with a median age of 27 (age range 21 days to 63 years) years underwent transcatheter intervention of CoA. Of them, 15 patients with concomitant cardiac anomalies underwent hybrid (n = 5) or staged (n = 10) procedures. In all 6 (5.8%) patients, subclavian artery protection techniques were used and successfully avoided subclavian artery obstruction. Systolic blood pressure decreased from 148.5 ± 21.9 mm Hg to 121.7 ± 14.5 mm Hg (p <0.001), which remained stable during a median follow-up of 37.7 months. The left ventricular mass index decreased from 128.6 [100.9, 181.7] to 99.1 [82.1, 137.4] g/m<sup>2</sup> in men (p = 0.006) and from 106.2 [93.5, 140.8] to 78.8 [59.2, 99.5] g/m<sup>2</sup> in women (p <0.001). The overall survival during the follow-up was 98.1%. A total of 6 patients (5.8%) required reintervention, otherwise, there were no cardiac, aortic, or neurologic events. In conclusion, this study provides promising long-term results of transcatheter intervention in CoA patients. The subclavian artery protection and hybrid strategy appeared valuable in complex anatomies.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"65-71"},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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