American Journal of Cardiology最新文献

{"title":"Evaluating Patients With Chest Pain Using the Recalibrated HEART Score and a Single High Sensitive Cardiac Troponin Measurement.","authors":"Vernon V S Bonarjee","doi":"10.1016/j.amjcard.2024.09.016","DOIUrl":"10.1016/j.amjcard.2024.09.016","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"91-92"},"PeriodicalIF":2.3,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epinephrine for Refractory No-Reflow During Percutaneous Coronary Interventions.","authors":"Fernando Alfonso, Josep Gómez-Lara, Fernando Rivero","doi":"10.1016/j.amjcard.2024.08.023","DOIUrl":"10.1016/j.amjcard.2024.08.023","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"88-90"},"PeriodicalIF":2.3,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Updated Invasive Right Ventricular and Pulmonary Hemodynamics on Long-Term Outcomes in Patients With Mitral Valve Transcatheter Edge-to-Edge Repair.","authors":"Giulia Masiero, Federico Arturi, Elisa Boscolo Soramio, Luca Nai Fovino, Tommaso Fabris, Francesco Cardaioli, Andrea Panza, Giulia Lorenzoni, Massimo Napodano, Chiara Fraccaro, Giuseppe Tarantini","doi":"10.1016/j.amjcard.2024.11.010","DOIUrl":"10.1016/j.amjcard.2024.11.010","url":null,"abstract":"<p><p>Right-sided cardiac catheterization (RHC) is selectively recommended in mitral valve transcatheter edge-to-edge (M-TEER) workup because right ventricle (RV) hemodynamic parameters predict adverse outcomes. This study examines the impact of RV hemodynamics and the prognostic value of the 2022 European Society of Cardiology (ESC) pulmonary hypertension definitions on outcomes after M-TEER. Of 152 patients treated with M-TEER for symptomatic severe mitral regurgitation (MR) between December 2014 and February 2024 at our tertiary center, 71 underwent elective RHC before the procedure. The primary outcomes assessed were all-cause mortality and a composite of heart failure hospitalization and death at the longest available follow-up. In a cohort of 152 mostly male patients (64%) with a median age of 79 years who were treated for symptomatic severe MR, 71 underwent elective RHC. The causes were categorized as degenerative (47%), functional ventricular (41%), and atrial (12%). Pulmonary hypertension (PH) was common, with 74% showing mean pulmonary artery pressure (mPAP) >20 mm Hg and 39% with pulmonary vascular resistance (PVR) >2 Wood Units. Success rates were high, with technical, device, and procedural success at 97%, 88%, and 84%, respectively. At a median follow-up of 681 days, all-cause mortality was 50%, and the composite outcome (death or heart failure hospitalizations) occurred in 61%. Key hemodynamic parameters, including mPAP, PVR, and the tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio, were independently linked to mortality risk. Kaplan-Meier analysis found significant associations with mPAP >20 mm Hg and pulmonary capillary wedge pressure >15 mm Hg for long-term mortality, whereas the 2022 ESC PH thresholds showed greater sensitivity, correlating with increased mortality risk. In patients with severe MR who undergo M-TEER, most RV invasive hemodynamic parameters are linked to adverse long-term outcomes, with mPAP, PVR, and the tricuspid annular plane systolic excursion/systolic pulmonary artery pressure ratio identified as independent predictors of mortality. Despite the study's limited sample size, the updated ESC PH definitions enhance prognostic assessment.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":"99-106"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to 'Non-Invasive Assessment of Left Ventricular Pressure-Volume Relations: Inter- and Intra-Observer Variability and Assessment Across Heart Failure Subtypes' [American Journal of Cardiology 184 (2022) 48-55].","authors":"Jonathan Edlund, Per M Arvidsson, Anders Nelsson, J Gustav Smith, Martin Magnusson, Einar Heiberg, Katarina Steding-Ehrenborg, Håkan Arheden","doi":"10.1016/j.amjcard.2024.12.016","DOIUrl":"10.1016/j.amjcard.2024.12.016","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal Intravascular Ultrasound-Guided Percutaneous Coronary Intervention in Patients with Multivessel Disease and Chronic Kidney Disease.","authors":"Ko Yamamoto, Hiroki Shiomi, Ryusuke Nishikawa, Takeshi Morimoto, Akiyoshi Miyazawa, Toru Naganuma, Satoru Suwa, Takanari Fujita, Takenori Domei, Shojiro Tatsushima, Yukihiro Hamaguchi, Yuji Nishimoto, Kensho Matsuda, Yohei Takayama, Jun Kuribara, Hidekuni Kirigaya, Kohei Yoneda, Masataka Shigetoshi, Takafumi Yokomatsu, Kazushige Kadota, Kenji Ando, Kiyoshi Hibi, Koh Ono, Takeshi Kimura","doi":"10.1016/j.amjcard.2024.12.020","DOIUrl":"https://doi.org/10.1016/j.amjcard.2024.12.020","url":null,"abstract":"<p><p>There is a scarcity of data on clinical outcomes after intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) in patients with multivessel disease and chronic kidney disease (CKD). The OPTIVUS-Complex PCI study multivessel cohort was a prospective multicenter single-arm trial enrolling 1015 patients who underwent multivessel IVUS-guided PCI including left anterior descending coronary artery target with an intention to meet the prespecified OPTIVUS criteria for optimal stent expansion. We compared the clinical outcomes between patients with and without CKD. The primary endpoint was a composite of death, myocardial infarction, stroke, or any coronary revascularization. There were 528 patients (52.0%) without CKD (estimated glomerular filtration rate [eGFR] >=60 mL/min/1.73m²), 391 patients (38.5%) with moderate CKD (60> eGFR >=30 mL/min/1.73m²), and 96 patients (9.5%) with severe CKD (eGFR <30 mL/min/1.73m² or hemodialysis). The rate of meeting OPTIVUS criteria was not different across the 3 groups. The cumulative 1-year incidence of the primary endpoint was 9.1%, 9.0%, and 22.1% in patients without CKD, with moderate CKD, and with severe CKD, respectively (log-rank P<0.001). After adjusting confounders, the higher risk of severe CKD relative to no CKD remained significant for the primary endpoint (HR, 2.42; 95%CI, 1.30-4.25; P=0.01), while the risk of moderate CKD relative to no CKD was not significant for the primary endpoint (HR, 0.97; 95%CI, 0.61-1.53; P=0.88). In conclusion, among patients who underwent multivessel IVUS-guided PCI, and were managed with contemporary clinical practice, 1-year clinical outcomes were worse in patients with severe CKD, while 1-year clinical outcomes were not different between patients without CKD and with moderate CKD.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Ascending Aortic Dissection Masquerading as a ST Elevation Myocardial Infarction.","authors":"Ariane Lemieux, Helen Hashemi, Charles S Roberts, Jeffrey M Schussler","doi":"10.1016/j.amjcard.2024.12.019","DOIUrl":"https://doi.org/10.1016/j.amjcard.2024.12.019","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reader's Comment: Routine Usage of Impella for High-Risk Percutaneous Coronary Intervention.","authors":"William W O'Neill","doi":"10.1016/j.amjcard.2024.12.018","DOIUrl":"https://doi.org/10.1016/j.amjcard.2024.12.018","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors and long-term prognostic significance of bailout stenting during percutaneous coronary interventions with sirolimus-coated balloon: a subanalysis of the EASTBOURNE study.","authors":"Filippo Luca Gurgoglione, Dario Gattuso, Antonio Greco, Giorgio Benatti, Giampaolo Niccoli, Bernardo Cortese","doi":"10.1016/j.amjcard.2024.12.015","DOIUrl":"https://doi.org/10.1016/j.amjcard.2024.12.015","url":null,"abstract":"<p><p>Percutaneous coronary intervention (PCI) with drug-coated balloon (DCB) has been expanding progressively in recent years. Convincing evidence demonstrated the ability of some DCB to promote positive vessel remodeling with potential clinical benefits at follow-up. When PCI with DCB results in suboptimal angiographic results (residual stenosis >30% or type C-F dissection), bailout stenting (BS) implantation is recommended to mitigate the risk of abrupt vessel occlusion or restenosis. However, clinical studies focusing on BS during PCI with DCB are scarce. The aim of this study was to compare the 2-year clinical outcomes of patients requiring BS with those who underwent sirolimus-coated balloon (SCB)-only PCI and to investigate clinical and angiographic predictors of BS. We conducted a post-hoc analysis of the prospective, multicenter, EASTBOURNE study. The overall cohort was stratified into two study groups: patients requiring BS versus those who underwent SCB-only PCI. The primary endpoint was target lesion revascularization (TLR) at 24-month follow-up. Propensity Score Matching (PSM) was utilized to balance clinical and procedural characteristics between the two study groups. The study population included 2084 patients for a total of 2318 treated lesions. Of them, 181 [7.8%] required BS for suboptimal results during PCI with SCB. Coronary lesions requiring BS were more frequently de-novo stenoses (p = 0.016) and were longer (p = 0.012) and with a smaller median reference vessel diameter (p < 0.001). At 24 months, TLR occurred in 133 [6.4%] patients. The two study groups experienced a similar rate of TLR both in the unmatched cohort (6.3% in the SCB-only group vs. 7.3% in the BS group, p=0.683) and after PSM analysis (4.2% in the SCB-only group vs. 8.5% in the BS group, p=0.223). These results were consistent when considering subpopulations with de-novo lesions, ISR, large and small vessel disease. Revascularization of de-novo lesions and smoking habit were independent positive predictors of BS, while the SCB inflation time was an independent negative predictor of BS by multivariable logistic analysis in the overall population. On the other hand, we did not record any case of vessel thrombosis during follow up. In conclusion, bailout stenting was associated with similar 2-year outcomes compared to SCB-only PCI and thus appear to be a safe bailout strategy for suboptimal angiographic results after DCB angioplasty.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Transcatheter Approach to Partial Anomalous Pulmonary Venous Return: A Case Series.","authors":"Omar Abdel-Razek, Nhi Vo, Jeffrey Weinstein, Cyrus A Koldani, David Liu, Roger Laham","doi":"10.1016/j.amjcard.2024.12.014","DOIUrl":"https://doi.org/10.1016/j.amjcard.2024.12.014","url":null,"abstract":"<p><p>Our study presents cases demonstrating the technique and safety of percutaneous occlusion of adult patients with partial anomalous pulmonary venous return (PAPVR). PAPVR is a rare condition that is traditionally treated surgically. Percutaneous interventions are rarely reported. Most patients with PAPVR present in youth and are surgical candidates. Among non-surgical candidates or those who prefer a percutaneous approach there is little available data to guide therapy. Patients with PAPVR and indications for intervention were treated with percutaneous techniques to occlude anomalous venous return and relieve the hemodynamic effects of these anomalies. Several different percutaneous techniques were used, sometimes in tandem to achieve occlusion. Percutaneous closure was achieved successfully in three cases with improvement in symptoms as well as improvement in hemodynamic status. Two patients achieved positive remodeling in right chamber sizes. In conclusion, Percutaneous occlusion of PAPVR is feasible with a multitude of transcatheter options available. This represents a novel approach to the adult patient with PAPVR, specifically those without a surgical option. Condensed Abstract: Partial anomalous pulmonary venous return (PAPVR) is a rare congenital condition which is traditionally treated surgically. Adult patients with congenital heart disease are potentially non-surgical candidates and as such benefit from percutaneous approaches. Our study describes the safety and feasibility of percutaneous closure of PAPVR as well as the positive impact on hemodynamic and chamber measures.</p>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of atrial fibrillation and smoking history on brain deficits.","authors":"Ashwin Balu, Gregory Y H Lip","doi":"10.1016/j.amjcard.2024.12.010","DOIUrl":"https://doi.org/10.1016/j.amjcard.2024.12.010","url":null,"abstract":"","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}