American Journal of Cardiology最新文献

Key Concepts in Cardiovascular Secondary Prevention: A Case-Based Review.

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-04 DOI: 10.1016/j.amjcard.2025.03.035

Shruti Revankar, Nezar Shakra, J Michael DiMaio, Anandita Agarwala

引用次数: 0

The Outcomes of Physiological Ventricular Rhythm Resetting with AV Node Ablation and Left Bundle Branch Pacing in Patients with AF-Induced Cardiomyopathy: A Prospective Cohort Study.

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-04 DOI: 10.1016/j.amjcard.2025.03.044

Wen Yang, Zhixin Jiang, Shengchan Wang, Chun Chen, Xiujuan Zhou, Qijun Shan

{"title":"The Outcomes of Physiological Ventricular Rhythm Resetting with AV Node Ablation and Left Bundle Branch Pacing in Patients with AF-Induced Cardiomyopathy: A Prospective Cohort Study.","authors":"Wen Yang, Zhixin Jiang, Shengchan Wang, Chun Chen, Xiujuan Zhou, Qijun Shan","doi":"10.1016/j.amjcard.2025.03.044","DOIUrl":"https://doi.org/10.1016/j.amjcard.2025.03.044","url":null,"abstract":"The mechanism of AF-induced cardiomyopathy (AF-CM) is still unclear. Expect for heart rate, atrial contraction lost and ventricular rhythm irregularity are believed as possible contributors to AF-CM. This study aimed to investigate ventricular rhythm irregularity effects on AF-CM. The AF-CM patients underwent the physiological ventricular rhythm resetting (PVRR) with atrioventricular node ablation combined with left bundle branch pacing or pharmacological therapy. To avoid heart rate effects, the heart rate (HR) setting according to preoperative Holter averages heart rate for each patient in the PVRR group. The primary endpoint was the echocardiographic response rate, defined as an absolute increase of left ventricular ejection fraction (LVEF) > 5%. Secondary endpoints included heart failure (HF) rehospitalization and worsening HF. Finally, 71 patients (mean age 65±11 years, 36 PVRR and 35 no-PVRR group) were enrolled this study. Compared with no-PVRR group, the PVRR without changed pre-and post-procedure HR significantly enhance echocardiographic response rate (86.1% vs. 31.4%, P<0.001), improve LVEF (12.0±6.6% vs. 4.0±8.1%, P<0.001), and shorten left ventricular end-diastolic diameter, and left ventricular end-systolic diameter (-4.6±4.1mm vs. -1.7±5.5mm, P<0.05; -6.8±3.8mm vs. -2.4±6.3mm, P<0.01, respectively) in 13.1±6.6 months follow-up. Furthermore, HF rehospitalization and worsening HF rates were significantly lower in the PVRR group (5.6% vs. 31.4%, P< 0.01). In conclusion, the ventricular rhythm irregularity is an important reversible contributor for AF-CM. The PVRR significantly enhances cardiac function, lowers HF rehospitalization and worsening HF rates. The PVRR could become a promising therapeutic strategy for AF-CM patients.","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing Unanswered Questions in Hemolysis Following SAPIEN 3 Ultra RESILIA Valve Implantation 解决 SAPIEN 3 Ultra RESILIA 瓣膜植入术后溶血的未解问题。

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-03 DOI: 10.1016/j.amjcard.2025.03.040

Ashfaq Ahmad , Ayesha Ahmad , Javed Iqbal , Arej iltaf , Ayesha Parvaiz Malik

引用次数: 0

Large Bore Sheath Technology and Hemostasis Efficacy After Transfemoral Transcatheter Aortic Valve Implantation 经口经导管主动脉瓣植入术后的大孔径鞘技术和止血效果。

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-03 DOI: 10.1016/j.amjcard.2025.03.045

Fortunato Iacovelli MD, PhD , Alessandro Cafaro MD , Antonio Pignatelli MD , Osvaldo Burattini MD , Francesco Spione MD , Luigi Salemme MD , Angelo Cioppa MD , Armando Pucciarelli MD , Grigore Popusoi MD , Eugenio Stabile MD, PhD , Tullio Tesorio MD

引用次数: 0

Rural/urban Disparities in Cardiovascular Disease in the US - What Can be Done to Improve Outcomes for Rural Americans?

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-02 DOI: 10.1016/j.amjcard.2025.03.033

Jacob B Pierce, Spencer M Ng, Joy A Stouffer, Clark A Williamson, George A Stouffer

引用次数: 0

Comments: Impact of Prereperfusion Left Ventricle Unloading on ST-Segment Elevation Myocardial Infarction According to the Onset-to-Unloading Time.

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-01 DOI: 10.1016/j.amjcard.2025.03.030

Jayadevan Sreedharan, Anshul Yadav, Neelesh Gupta, Rajeev Gupta

引用次数: 0

Prognostic Value of Resting Heart Rate and Heart Rate Variability in the 12-lead Electrocardiogram: Mortality Data From the CODE Database.

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-01 DOI: 10.1016/j.amjcard.2025.03.038

Diego N Moraes, Bruno R Nascimento, Magda C Pires, Gabriela Miana de M Paixão, Peter W Mac Farlane, Antonio Luiz P Ribeiro

{"title":"Prognostic Value of Resting Heart Rate and Heart Rate Variability in the 12-lead Electrocardiogram: Mortality Data From the CODE Database.","authors":"Diego N Moraes, Bruno R Nascimento, Magda C Pires, Gabriela Miana de M Paixão, Peter W Mac Farlane, Antonio Luiz P Ribeiro","doi":"10.1016/j.amjcard.2025.03.038","DOIUrl":"https://doi.org/10.1016/j.amjcard.2025.03.038","url":null,"abstract":"Resting Heart Rate (HR) and Heart Rate Variability (HRV) reflect cardiovascular autonomic control and are implicated as prognostic factors. We aimed to evaluate the prognostic value of HR and HRV in a tele-ECG cohort network. We assessed unique 12-lead ECGs recorded from patients ≥16 years, from a tele-ECG database in Brazil, between 2010-2017. Variables of interest were HR and standard deviation of normal RR intervals (SDNN). Four Cox models were adjusted to evaluate the association between HR and HRV and the outcomes of interest (all-cause and cardiovascular mortality, assessed by ICD codes from death certificates): model 1. Unadjusted; 2. Adjusted for sex and age; 3. Model 2 + risk factors and clinical comorbidities; 4. Model 3 + adjustment for HRV or HR, respectively. At total 992.611 individuals were included, median age of 55 years. In 6 years, there were 33.292 (3,37%) deaths, 21% due to cardiovascular causes. After adjustments (model 4), all HR quartiles were independently associated with a progressively increased risk of all-cause mortality, being 88% higher for the 4th quartile (HR=1.88 (95%CI 1.77-1.89). Similarly, the 1st and 2nd HRV quartiles remained associated with increased all-cause mortality (1st quartile HR=1.42 (95%CI 1.37-1.47) in the final model. HR (4th quartile: HR=1.77 95%CI 1.65-1.91) and HRV (1st quartile: HR=1.33, 95%CI 1.23-1.44) were also independent predictors (model 4) of cardiovascular mortality. In conclusion, in a large cohort of Brazilian adults, baseline HR and HRV were independent predictors of all-cause and cardiovascular mortality, even when adjusted for each other.","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Site-Level Variation and Factors Associated With an Outpatient Intravenous Diuretic Strategy for Worsening Heart Failure

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-01 DOI: 10.1016/j.amjcard.2025.03.041

Hubert B. Haywood MD, MBA , Lisa A. Kaltenbach MS , Uchechukwu Ikeaba MS , Gregg C. Fonarow MD , Karen Chiswell PhD , Veraprapas Kittipibul MD , Muhammad Shahzeb Khan MD, MSc , Megha Gupta BA , Best Uchehara MD, MBA , Bradley G. Hammill DrPH , Javed Butler MD, MPH, MBA , Adrian F. Hernandez MD, MHS , G. Michael Felker MD, MHS , Stephen J. Greene MD

引用次数: 0

Clinical Characteristics and Outcomes Stratified by Time to ST-Segment Elevation Myocardial Infarction Presentation

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-01 DOI: 10.1016/j.amjcard.2025.03.043

Yosuke Kakimoto MD , Ko Yamamoto MD , Masahiro Natsuaki MD , Goro Yoshioka MD , Yuhei Goriki MD , Kohei Kamishita MD , Kensuke Yokoi MD , Atsushi Kawaguchi PhD , Mitsuhiro Shimomura MD , Keiki Yoshida MD , Shinjo Sonoda MD , Koichi Node MD , SAGA-ACS registry investigators

{"title":"Clinical Characteristics and Outcomes Stratified by Time to ST-Segment Elevation Myocardial Infarction Presentation","authors":"Yosuke Kakimoto MD , Ko Yamamoto MD , Masahiro Natsuaki MD , Goro Yoshioka MD , Yuhei Goriki MD , Kohei Kamishita MD , Kensuke Yokoi MD , Atsushi Kawaguchi PhD , Mitsuhiro Shimomura MD , Keiki Yoshida MD , Shinjo Sonoda MD , Koichi Node MD , SAGA-ACS registry investigators","doi":"10.1016/j.amjcard.2025.03.043","DOIUrl":"10.1016/j.amjcard.2025.03.043","url":null,"abstract":"<div><div>There were few data on the clinical characteristics of ST-segment elevation myocardial infarction (STEMI) patients with late presentation (long symptom onset to door [hospital arrival] time). Among 719 consecutive patients with STEMI who underwent percutaneous coronary intervention (PCI) in the SAGA-ACS registry, we compared baseline characteristics and clinical outcomes between patients with early presentation (symptom onset to door time <2.3 hours) and late presentation (≥2.3 hours). The cut-off point of 2.3 hours was the median value for the present study population. The median onset to door time was 1.3 hours in the early presentation group, and 4.8 hours in the late presentation group. Door to balloon time was not different between the groups (62.0 minutes vs 60.5 minutes). Late night to early morning onset (OR, 2.03; 95% CI, 1.45 to 2.85), age ≥75 years (OR, 1.56; 95% CI, 1.09 to 2.22), and women (OR, 1.49; 95% CI, 1.03 to 2.16) were independently associated with the late presentation, while culprit lesions in right coronary artery (RCA) was inversely associated the late presentation (OR, 0.62; 95% CI, 0.46 to 0.85). During the median 2.7 years follow-up, the cumulative incidence of all-cause death was numerically, but not statistically, higher in the late presentation group than in the early presentation group (16.3% vs 11.6% at 3 years, HR, 1.42; 95% CI, 0.97 to 2.07; p = 0.07). In conclusion, among patients with STEMI who underwent PCI, late night to early morning onset, advanced age, women, and culprit lesions in non-RCA were strongly associated with the late presentation. Strategies for minimizing symptom onset to door time should be targeted especially in these patients.</div></div>","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":"247 ","pages":"Pages 57-63"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Peripheral Arterial Disease on Clinical Outcomes of Patients Undergoing Complex vs Non-Complex Percutaneous Coronary Intervention.

IF 2.3 3区医学

American Journal of Cardiology Pub Date : 2025-04-01 DOI: 10.1016/j.amjcard.2025.03.037

Michael Gao, Angelo Oliva, Raman Sharma, Frank Kalaba, Samantha Sartori, Serdar Farhan, Kenneth Smith, Birgit Vogel, Prakash Krishnan, George Dangas, Roxana Mehran, Annapoorna Kini, Samin Sharma

{"title":"Impact of Peripheral Arterial Disease on Clinical Outcomes of Patients Undergoing Complex vs Non-Complex Percutaneous Coronary Intervention.","authors":"Michael Gao, Angelo Oliva, Raman Sharma, Frank Kalaba, Samantha Sartori, Serdar Farhan, Kenneth Smith, Birgit Vogel, Prakash Krishnan, George Dangas, Roxana Mehran, Annapoorna Kini, Samin Sharma","doi":"10.1016/j.amjcard.2025.03.037","DOIUrl":"https://doi.org/10.1016/j.amjcard.2025.03.037","url":null,"abstract":"Peripheral arterial disease (PAD) often predicts poor outcomes in patients undergoing percutaneous coronary intervention (PCI). Here we examine the impact of PAD in patients receiving complex PCI (CPCI) and non-complex PCI. Patients undergoing PCI at the Mount Sinai Hospital between 2012 and 2022 were stratified by the presence of CPCI and PAD. The primary outcome was major adverse cardiovascular events (MACE), a composite of death, myocardial infarction, target vessel revascularization, or stroke within 1 year; secondary endpoints included bleeding events. An adjusted Cox proportional hazard method was used to evaluate risks of each outcome within each subgroup. Among 20,376 patients, 8,200 (40.2%) had CPCI and 1,959 (9.6%) had PAD. PAD patients were older and more likely to be female and have risk factors such as diabetes and smoking and were more commonly discharged with anticoagulants. 1-year risk of MACE was significantly higher for patients with PAD in both CPCI (19.6% vs. 14.4%, adj. hazard ratio (HR) 1.31, 95% confidence interval (CI) 1.08-1.58, P= 0.006) and no-CPCI strata (13.9% vs. 9.2%, adj. HR 1.35, 95% CI 1.12-1.64, P = 0.002; P-interaction = 0.349). Bleeding events were also more frequent in PAD patients for CPCI (8.5% vs. 5.5%, adj. HR 1.40, 95% CI 1.07-1.84, P = .014) and no-CPCI (7.1% vs. 4.3%, adj. HR 1.52, 95% CI 1.18-1.96, P = 0.001; P-interaction = 0.608). In conclusion, presence of PAD is associated with a significantly increased risk of MACE and bleeding after PCI, regardless of procedural complexity.","PeriodicalId":7705,"journal":{"name":"American Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0