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American journal of physiologic imaging最新文献

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Diagnostic and functional implications of pelvocalyceal system nonvisualization on [99m]Tc-DTPA renal images. [99m]Tc-DTPA肾图像上盆腔系统不可见的诊断和功能意义。

American journal of physiologic imaging Pub Date : 1990-01-01

S Sostre, H H Drew, Z Szabo, H Rivera-Luna, E E Camargo

{"title":"Diagnostic and functional implications of pelvocalyceal system nonvisualization on [99m]Tc-DTPA renal images.","authors":"S Sostre, H H Drew, Z Szabo, H Rivera-Luna, E E Camargo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Most functional abnormalities observed on 99mTc-DTPA renal images probably reflect GFR changes and the functional consequences of these changes. We have noted an unexplained failure of the pelvocalyceal system to visualize in some patients during the renal imaging sequence. This led us to study the relationship between pelvocalyceal nonvisualization and GFR, and to search for plausible explanations of the absent visualization. In 41 patients with combined renal imaging and GFR determinations, pelvecalyceal nonvisualization was seen only with GFR values below 20 ml/min. The sign was 100% sensitive and 100% specific predicting GFR less than 20 and serum creatinine above 2.9 mg/dl. In vitro studies revealed markedly reduced amounts of DTPA chelate in the urine of patients with GFR less than 20, but in addition they had decreased tubular water reabsorption leading to dilution of the already reduced urine chelate contents. The reduced amounts of 99mTc-DTPA per ml of pelvocalyceal urine may account for the nonvisualization of this system. It may be that the intensity of the pelvocalyceal system reflects the adequacy of both the GFR, and the water reabsorptive function of the renal tubules.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"5 3","pages":"125-31"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13435504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of diagnostic procedures on stratified populations: application on the quantification of thallium myocardial perfusion scintigraphy. 分层人群诊断程序的验证:铊心肌灌注显像定量的应用。

American journal of physiologic imaging Pub Date : 1989-01-01

M L Goris, J Bretille, S Askienazy, G P Purcell, V Savelli

引用次数: 0

Pulsed Doppler sonography of the hepatoduodenal ligament: efficacy and ease of performance. 肝十二指肠韧带的脉冲多普勒超声检查:有效性和易用性。

American journal of physiologic imaging Pub Date : 1989-01-01

D S Henley, M B Johnson, P M Colletti, W D Boswell, J M Halls, P W Ralls

引用次数: 0

Pharmaceutical quality control of radiolabeled monoclonal antibodies and their fragments. 放射性标记单克隆抗体及其片段的药品质量控制。

American journal of physiologic imaging Pub Date : 1989-01-01

S J DeNardo, G L DeNardo, J S Peng

引用次数: 0

Physiological considerations in radionuclide imaging of the penis during impotence therapy. 阳痿治疗期间阴茎放射性核素显像的生理考虑。

American journal of physiologic imaging Pub Date : 1989-01-01

T K Chaudhuri, S Fink, R H Burger, I C Netto, J D Palmer

引用次数: 0

Technetium-99m haemaccel: a new lymphoscintigraphic agent. 锝-99m血凝素:一种新的淋巴显像剂。

American journal of physiologic imaging Pub Date : 1989-01-01

S Sadek, A Owunwanne, T Yacoub, H M Abdel-Dayem

引用次数: 0

Clinical-physiologic correlates of Alzheimer's disease and frontal lobe dementia. 阿尔茨海默病和额叶痴呆的临床生理学相关性

American journal of physiologic imaging Pub Date : 1989-01-01

W J Jagust, B R Reed, J P Seab, J H Kramer, T F Budinger

{"title":"Clinical-physiologic correlates of Alzheimer's disease and frontal lobe dementia.","authors":"W J Jagust, B R Reed, J P Seab, J H Kramer, T F Budinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thirty patients with degenerative dementia underwent clinical evaluation, neuropsychological testing, and single photon emission computed tomography (SPECT) with the blood flow tracer [123I]-N-isopropyl-p-iodoamphetamine. Five of these patients were clinically and psychologically different from the others, demonstrating predominant behavioral disturbances with relative preservation of memory function. These five patients, who were felt to have a frontal lobe dementia (FLD), showed SPECT perfusion patterns which differed from the remaining 25 patients, who were diagnosed as having Alzheimer's disease (AD), and from 16 healthy control subjects. The FLD patients showed diminished perfusion in orbitofrontal, dorsolateral frontal, and temporal cortex relative to controls, while the AD patients showed lower perfusion in temporal and parietal cortex than controls. The FLD patients also showed hypoperfusion in both frontal cortical regions relative to AD patients. The pattern of performance on neuropsychological testing paralleled these differences in regional perfusion. These results suggest that clinical evaluation and physiological imaging may enable the differentiation of groups of degenerative dementia patients during life.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"4 3","pages":"89-96"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13928878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid MR imaging of renal perfusion: a comparative study of GdDTPA, albumin-(GdDTPA), and magnetite. 肾灌注的快速MR成像:GdDTPA、白蛋白-(GdDTPA)和磁铁矿的比较研究。

American journal of physiologic imaging Pub Date : 1989-01-01

P F Daly, J B Zimmerman, J S Gillen, G L Wolf

{"title":"Rapid MR imaging of renal perfusion: a comparative study of GdDTPA, albumin-(GdDTPA), and magnetite.","authors":"P F Daly, J B Zimmerman, J S Gillen, G L Wolf","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>MR contrast agents injected intravenously reach the kidney very rapidly. Modification of a gradient recalled echo sequence allowed acquisition of 32 sequential MR images each 3.9 s apart on a 1.5 T clinical imager. This sequence was then used to observe the renal accumulation of contrast agent following an intravenous bolus of 100 microns/kg GdDTPA, 60 microns/kg albumin-(GdDTPA) or 9.6 and 40 mg/kg of 0.7 mu magnetic latex microspheres in rats or rabbits. Serial changes in image intensity were obtained with 3.9 s temporal and 0.08 ml spatial resolution. The renal cortical response to GdDTPA was similar to changes in blood 1/T1, but the medulla showed first a signal enhancement owing to the initial increased T1 relaxation followed by loss of signal as increased concentrations caused T2 relaxation to become predominant. Changes in intensity caused by magnetite and albumin-(GdDTPA) correlated with the 1/T1 changes observed in blood samples consistent with the predominantly intravascular location of these two agents. We conclude that MRI provides high spatial resolution with sufficient temporal resolution to record tissue response to an intravenous bolus of MR contrast agents.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"4 4","pages":"165-74"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13837005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of indium-111 oxine to study pulmonary and hepatic leukocyte sequestration in endotoxin shock and effects of the beta-2 receptor agonist terbutaline. 利用铟-111氧研究内毒素休克时肺和肝白细胞的隔离及β -2受体激动剂特布他林的作用。

American journal of physiologic imaging Pub Date : 1989-01-01

G H Sigurdsson, J T Christenson, M al-Mousawi, A Owunwanne

{"title":"Use of indium-111 oxine to study pulmonary and hepatic leukocyte sequestration in endotoxin shock and effects of the beta-2 receptor agonist terbutaline.","authors":"G H Sigurdsson, J T Christenson, M al-Mousawi, A Owunwanne","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The dynamic behavior of indium-111 oxine-labeled leukocytes was simultaneously recorded in multiple organs during endotoxin shock in sheep. Also, the effects of the beta-2 receptor agonist terbutaline were studied. An experimental protocol was designed to mimic a clinical condition in an intensive care setting as far as possible. The animals were ventilated with 50% oxygen to avoid hypoxemia and were given large amounts of intravenous fluids to reduce adverse effects of hypovolemia. A moderate dose of E. coli endotoxin (10 micrograms/kg bwt) was given by intravenous infusion to 14 adult sheep, seven of them receiving continuous intravenous infusion of terbutaline (20 micrograms/kg/hr) during 4 hr, starting 30 min after endotoxin, when signs of lung injury had developed. The other seven acted as controls. A marked pulmonary and hepatic leukocyte sequestration together with a sharp drop in leukocyte counts in peripheral blood occurred within minutes after start of the endotoxin infusion in both groups. However, no changes were observed in the kidneys or the gut. After 60 min and until the end of the experiment, there was a significantly lower activity in the lungs and in the liver of the animals treated with terbutaline than in the controls (P less than .01). Furthermore, less marked hemodynamic and respiratory alterations occurred in the terbutaline group compared with the controls. This study confirms the results of other investigators showing that significant leukocyte sequestration occurs in the lungs during endotoxemia, but it also demonstrates that leukocytes sequestrate in the liver, although slightly less than in the lungs.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"4 4","pages":"136-42"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13718865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of infarct size of acute myocardial infarction in dogs by magnetic resonance imaging and gadolinium-DTPA: comparison with indium-111 antimyosin imaging. 磁共振成像和钆- dtpa测定犬急性心肌梗死梗死面积:与铟-111抗肌球蛋白显像的比较。

American journal of physiologic imaging Pub Date : 1989-01-01

T Nishimura, Y Yamada, M Hayashi, T Kozuka, T Nakatani, H Noda, H Takano

{"title":"Determination of infarct size of acute myocardial infarction in dogs by magnetic resonance imaging and gadolinium-DTPA: comparison with indium-111 antimyosin imaging.","authors":"T Nishimura, Y Yamada, M Hayashi, T Kozuka, T Nakatani, H Noda, H Takano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acute myocardial infarctions were produced in nine dogs by ligation of the left anterior descending coronary artery. Twenty-four hours after ligation, 0.5 mM/kg of gadolinium (Gd)-DTPA was injected intravenously, followed by cardiectomy 30 min later. Indium-111 antimyosin was administered intravenously 6 hr before cardiectomy to compare the infarct size with Gd-DTPA contrast enhancement. Areas of Gd-DTPA contrast enhancement were closely correlated with those of indium-111 antimyosin uptake (r = .86), although the former showed slightly greater than the latter. Partial and complete enhancements were observed in three and six dogs, respectively. In the T1 and T2 maps, T1 relaxation times of the infarcted area showed greater T1 shortening compared with normal myocardium, whereas T2 relaxation times were not different between infarcted and normal myocardium. Thus, Gd-DTPA showed significant contrast enhancement of the infarcted area because of greater T1 shortening and the extent of Gd-DTPA contrast enhancement expressed the infarct size precisely.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"4 3","pages":"83-8"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13928877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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