Allergie et immunologie最新文献_第5页

Preventive symptomatic immunotherapy versus placebo in seasonal rhinitis due to grasses in children and to Parietaria in adult patients. 预防对症免疫疗法与安慰剂在儿童草性季节性鼻炎和成人鼻咽炎患者中的疗效比较。

Allergie et immunologie Pub Date : 2000-06-01

C Troise, D Bignardi, P Modena, C Pissacroia, F Di Berardino

{"title":"Preventive symptomatic immunotherapy versus placebo in seasonal rhinitis due to grasses in children and to Parietaria in adult patients.","authors":"C Troise, D Bignardi, P Modena, C Pissacroia, F Di Berardino","doi":"","DOIUrl":"","url":null,"abstract":"Background: EPD is the only preventive symptomatic immunotherapy available on the market and approved by competent bodies. Recent double-blind placebo controlled (DBPC) studies have demonstrated its efficacy in seasonal and perennial rhinitis. The aim of the study was to confirm the efficacy and safety of a single dose of immunotherapy administered six-eight weeks before the pollen season.Methods: Two simultaneous DBPC trials were carried out. The first consisted of 20 children with grass-pollen seasonal rhinitis (Bollate-Milano, Italy) and the second included 30 adult patients with Parietaria-pollen seasonal rhinitis (Genova, Italy). EPD was administered only to the active groups.Results: A significant difference in favour of the active treatment groups was seen in oral antihistamine use (p < 0.05) during the peak pollen seasons. Throughout the pollen seasons, rhinoconjunctivitis scores for the two groups in both studies presented no significant difference, even if the values were lower in the active groups.Conclusions: The oral antihistamine reduction, observed in the active groups during the seasonal period, supports the efficacy of this treatment, although a significant improvement in the rhinoconjunctivitis symptoms was not observed, probably due to the use of oral antihistamine in the placebo groups. The overall profile of the EPD was good. It could be particularly suited for short term therapy to prevent seasonal symptoms in allergic patients.","PeriodicalId":76988,"journal":{"name":"Allergie et immunologie","volume":"32 6","pages":"246-9"},"PeriodicalIF":0.0,"publicationDate":"2000-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21807384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Value of esophageal scintigraphy in exploration of a gastro-esophageal reflux in a respiratory patient]. [食道闪烁造影在呼吸道病人胃食管反流探查中的价值]。

Allergie et immunologie Pub Date : 2000-05-01

A Sonneville, H Ait-Tahar, F Baulieu, M Eder, I Menelet

引用次数: 0

[Incidence of sensitization to profilin in a population allergic to pollen: responsibility of profilin in pollen polysensitizations in patients with a normal level of total IgE]. [花粉过敏人群中对profile过敏的发生率:总IgE水平正常的患者中profile对花粉多致敏的责任]。

Allergie et immunologie Pub Date : 2000-05-01

R Dubost, N Ruet, P Deviller

{"title":"[Incidence of sensitization to profilin in a population allergic to pollen: responsibility of profilin in pollen polysensitizations in patients with a normal level of total IgE].","authors":"R Dubost, N Ruet, P Deviller","doi":"","DOIUrl":"","url":null,"abstract":"Unlabelled: The study had the aim of establishing the incidence of sensitization to profilin (a panallergen found in pollens and foods of vegetal origin) in pollen-allergic patients. We evaluated the consequences of such sensitizations on the results of specific IgE, the positivity of skin tests and clinical signs.Methods: 94 consenting patients, allergic to pollens (trees and/or grasses and/or weeds) replied to a questionnaire and had skin tests to purified profilin and measurement of serum anti-profilin IgE.Results: Two groups were defined: one group was sensitized to profilin (GSP), with positive skin test and anti profilin IgE of 31 patients, and a group non-sensitive to profilin (GNSP) (negative skin test and anti-profilin IgE) of 41 patients. Discordant results were found in 22 patients. Taking in account the two groups, sensitization to profilin was 43%. The two groups were homogenous for age, sex, ethnics and clinical signs. Food allergy was more frequent but not statistically different (p = 0.09) in the group GSP (51.6%) than the GNSP (31.7%), in particular allergy to fruits of the Rosaceae family. Pollen polysensitization (to three species, trees, weeds and grasses) was more frequent in the GSP group (64.5%) than the GNSP (12.5). Polysensitization to pollens and foods was also more frequent in the sensitized group (65.5%) than in the non-sensitized group (12.5%). In a sub-group with normal levels of total IgE pollen polysensitization was more frequent in patients who were sensitive to profilin. On biological investigation, sensitization to profilin influenced the result of anti-latex IgE and also the IgE to many vegetal allergens. These results show the value of seeking a sensitization to profilin in patients with pollinoses.","PeriodicalId":76988,"journal":{"name":"Allergie et immunologie","volume":"32 5","pages":"199-206"},"PeriodicalIF":0.0,"publicationDate":"2000-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21741959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Educational program for children with peanut allergy. 针对花生过敏儿童的教育项目。

Allergie et immunologie Pub Date : 2000-05-01

P Rancé, E Bidat

引用次数: 0

Asthma and respiratory symptoms among school children in United Arab Emirates. 阿拉伯联合酋长国学龄儿童的哮喘和呼吸道症状。

Allergie et immunologie Pub Date : 2000-04-01

F al-Maskari, A Bener, A al-Kaabi, N al-Suwaidi, N Norman, J Brebner

{"title":"Asthma and respiratory symptoms among school children in United Arab Emirates.","authors":"F al-Maskari, A Bener, A al-Kaabi, N al-Suwaidi, N Norman, J Brebner","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To determine the prevalence of asthma, wheezing, hay fever, and eczema among primary school children aged 6-13 years in United Arab Emirates (UAE).Design: A cross-sectional study on school children was performed using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires.Setting: Government primary school children in seven Emirates, in UAE.Subjects: Subjects were selected by a multi-stage stratified sampling design. 4200 children targeted for this study, but only 3200 children aged 6-13 years were agreed to participate and responded to the study. The overall response rate was 69.8%.Results: The prevalence of physician diagnosed asthma was 13%, in addition, the wheeze by history was 15.6%. Furthermore, the prevalence of nocturnal cough was 21%. On the other hand, the prevalence of eczema was 11% and hay fever was 14.9%. Parental asthma but not parental atopy was associated with an increased risk of asthma and wheezing in children.Conclusions: The prevalence of asthma and wheezing in UAE is consistent with that in neighbouring Gulf countries.","PeriodicalId":76988,"journal":{"name":"Allergie et immunologie","volume":"32 4","pages":"159-63"},"PeriodicalIF":0.0,"publicationDate":"2000-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21742190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Summaries from the annual reunion of the National Aerobiology Surveillance Network (RNSA). Part 2]. [国家航空生物学监测网(RNSA)年度聚会摘要]第2部分)。

Allergie et immunologie Pub Date : 2000-04-01

引用次数: 0

Concentration of airborne pollen from Cupressaceae in Lisbon. 里斯本柏科空气中花粉的浓度。

Allergie et immunologie Pub Date : 2000-03-01

A P Ramos, M J Marques, A Fabiao, J Santos-Pereira, A Todo-Bom, L Fontes, N Neuparth, P L da Mata

引用次数: 0

[AFEDA (Association Francaise d'Etudes des Ambroisies), its history, actions, and politics]. [AFEDA (Association Francaise d'Etudes des Ambroisies)，它的历史、行动和政治]。

Allergie et immunologie Pub Date : 2000-03-01

C Déchamp

引用次数: 0

Pathogenesis of allergic diseases: interactions between pollutants and pollens really important? 过敏性疾病的发病机制:污染物与花粉的相互作用真的重要吗?

Allergie et immunologie Pub Date : 2000-03-01

H Okudaira

{"title":"Pathogenesis of allergic diseases: interactions between pollutants and pollens really important?","authors":"H Okudaira","doi":"","DOIUrl":"","url":null,"abstract":"Nowadays, the prevalence of atopic diseases in so-called developed countries is estimated to exceed 30%. Furthermore, it may reach over 50% in two generations. Based on such facts, the so-called \"atopic predisposition\" can not be defined as an abnormal genotype consisting of certain \"atopic gene(s)\" possessed by a minority of unfortunate people. Rather, the gene(s) that cause atopic diseases reside in the common human gene repertoire, and several environmental factors would cause the overexpression of some constitutive gene(s), leading to the development of atopic diseases. The author considers that overexpression and production of Th2 cytokines, especially IL-5, may be a key event. The recent prevalence of atopic diseases in developed countries may be mediated by a change of Th2 polarization due to modern retrogression of environmental factors such as bacterial and viral infections that favor Th1 polarization. The \"atopic trait\" might be actually an \"atopic phenotype\" rather than an \"atopic genotype\". In other words, the atopic trait seems not to be a genotype that decides the development of an atopic disease on an all or nothing basis, but a phenotype that determines the susceptibility to the disease. Of course, the familial nature of atopic diseases is undeniable, but this does not necessarily indicate the genetic nature of atopic diseases. For example, if a parent suffers from tuberculosis, the possibility that the children will develop tuberculosis markedly increased. However, tuberculosis is a truly infectious disease. In this article, several environmental factors those may affect the recent sharp increase of atopic diseases are discussed.","PeriodicalId":76988,"journal":{"name":"Allergie et immunologie","volume":"32 3","pages":"94-6"},"PeriodicalIF":0.0,"publicationDate":"2000-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21661054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Variability of pollination and of pollen in Cypress]. [柏树传粉和花粉的变异性]。

Allergie et immunologie Pub Date : 2000-03-01

C Pichot

引用次数: 0