AIDS reviews最新文献_第7页

International outbreak of monkeypox in men having sex with men. 猴痘在男男性行为者中的国际暴发。

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-04-01 DOI: 10.24875/AIDSRev.M22000051

Vicente Soriano, Octavio Corral

引用次数: 11

A greater virulent HIV-1 subtype B variant has circulated in The Netherlands since the 1990's. 自20世纪90年代以来，一种毒性更强的HIV-1 B亚型变体在荷兰流行。

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-03-01 DOI: 10.24875/AIDSRev.M22000047

A. Treviño, V. Soriano

引用次数: 0

A Systematic Review and Meta-analysis to Estimate the Time from HIV Infection to Diagnosis for People with HIV. 通过系统回顾和元分析估算艾滋病毒感染者从感染艾滋病毒到确诊的时间。

IF 1.9 4区医学

AIDS reviews Pub Date : 2022-03-01 DOI: 10.24875/AIDSRev.21000007

Semiu O Gbadamosi, Mary Jo Trepka, Rahel Dawit, Rime Jebai, Diana M Sheehan

{"title":"A Systematic Review and Meta-analysis to Estimate the Time from HIV Infection to Diagnosis for People with HIV.","authors":"Semiu O Gbadamosi, Mary Jo Trepka, Rahel Dawit, Rime Jebai, Diana M Sheehan","doi":"10.24875/AIDSRev.21000007","DOIUrl":"10.24875/AIDSRev.21000007","url":null,"abstract":"Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a search of MEDLINE, Embase, and Google Scholar, supplemented by a hand search of bibliographies of articles, was conducted. Study information and outcome measures of time from HIV infection to diagnosis were synthesized. Random-effects metaanalyses were performed. The search identified 12 articles from 4541 unduplicated citations. Studies were conducted in the UK (k = 3), US (k = 3), France (k = 2), Australia (k = 1), Switzerland (k = 1), Netherlands (k = 1), and China (k = 1). The pooled meantime from HIV infection to diagnosis was 3.00 years (95% confidence interval: 2.16-3.84). From 1996 to 2002, meantime reduced from 4.68 to 2.66 years. Subsequently, it increased to 3.20 years in 2003 and remained relatively stable until 2015. In sub-group meta-analyses, men who have sex with men (MSM) had a meantime of 2.62 years (1.91-3.34), while for heterosexuals and people who inject drugs, it was 5.00 (4.15-5.86) and 4.98 (3.97-5.98) years, respectively. In the high- and upper-middle-income countries included in this study, persons live with undiagnosed HIV for about 3 year before being diagnosed. This period is shorter for MSM relative to people with infections attributable to other risk factors.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"24 1","pages":"32-40"},"PeriodicalIF":1.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636511/pdf/nihms-1733127.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9638996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HIV and liver disease. 艾滋病毒和肝病。

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-01-01 DOI: 10.24875/AIDSRev.M22000052

Jordi Navarro

引用次数: 1

Smoking among people living with HIV/AIDS: a bibliometric analysis (GAP_RESEARCH). 艾滋病毒/艾滋病感染者吸烟:文献计量学分析(GAPRESEARCH)。

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-01-01 DOI: 10.24875/AIDSRev.19000098

Bach Xuan-Tran, Carl A Latkin, Hai Thanh-Phan, Huong L Thi-Nguyen, Chi Linh-Hoang, Cyrus S H Ho, Roger C M Ho

{"title":"Smoking among people living with HIV/AIDS: a bibliometric analysis (GAPRESEARCH).","authors":"Bach Xuan-Tran, Carl A Latkin, Hai Thanh-Phan, Huong L Thi-Nguyen, Chi Linh-Hoang, Cyrus S H Ho, Roger C M Ho","doi":"10.24875/AIDSRev.19000098","DOIUrl":"https://doi.org/10.24875/AIDSRev.19000098","url":null,"abstract":"Tobacco smoking undermines the effectiveness of antiretroviral therapy (ART) among people living with HIV/AIDS (PLWHA) and potentially associates with other health problems. This study aimed to analyze the growth and content of research on smoking among PLWHA on Web of Science Database. Co-occurrence analysis and Jaccard's' similarity index calculation were performed to identify and visualize networks of countries collaboration, keywords co-occurrence, and research topics. Exploratory factor analysis was applied to the abstracts' contents to uncover research domains and landscapes. The number of publications increased by 14.55% annually in the period of 1991-2017, with 74% of total papers published within 2007-2017. A wide range of topics have been covered, notably co-morbidities, interventions on smoking abstinence and cessation, and the enforcing relationship of smoking cessation with antiretroviral treatment adherence. A shortage of studies on smoking among PLWHA in low- and middle-income countries, limited collaborations between countries outside of close geographical proximity and a lack of discussion on local contexts and psychosocial factors were found. Smoking among PLWHA has been being studied more extensively in recent years, enhancing our knowledge and awareness of the significant and specific effects smoking have on PLWHA, which, in turn, assisting the proposals and implementations of suitable solutions. However, more efforts should be made to examine and understand contextualized aspects, including culture and beliefs specific to each nation or smaller sub-population within a country, especially those currently under-researched, as well as psycho-behavioral factors to implement more effective interventions to reduce smoking among PLWHA.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"25 3","pages":"105-114"},"PeriodicalIF":2.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40670602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Antiretroviral therapy and weight gain in naive HIV-1 infected patient: a narrative review. 抗逆转录病毒治疗和初发HIV-1感染患者体重增加:一项叙述性综述

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-01-01 DOI: 10.24875/AIDSRev.21000092

Emilie Dupont, Jean Cyr-Yombi

{"title":"Antiretroviral therapy and weight gain in naive HIV-1 infected patient: a narrative review.","authors":"Emilie Dupont, Jean Cyr-Yombi","doi":"10.24875/AIDSRev.21000092","DOIUrl":"https://doi.org/10.24875/AIDSRev.21000092","url":null,"abstract":"The prevalence of obesity has increased dramatically in recent decades worldwide. An increase in the prevalence of obesity has also been observed among people living with HIV (PLHIV) in high and low incomes countries. Antiretroviral therapy (ART), by controlling the viral load (VL) and restoring cellular immunity, has improved the health status and life expectancy in PLHIV. However, the risk of developing non-AIDS events (NAEs) remains higher than the general population. Therefore, specific attention is given to managing risk factors associated with NAEs during the follow-up of PLHIV, including obesity. Factors related to weight gain in PLHIV include demographic factors, HIV disease-related factors, and ART-associated factors. In naive PLHIV, weight gain after the initiation of ART is expected. The weight gains observed are generally not severe even if there appear to be risk factors such as the advanced stage of disease (low CD4 cells count and high VL), female sex, black race, and taking integrase strand transfer inhibitors (INSTI) associated or not with tenofovir alafenamide fumarate (TAF). The role of each antiretroviral drug per-se remains to clarify. As INSTI ± TAF has been associated with significant weight gain, further research is needed to identify the individual-level factors predictive of weight gain, the mechanisms of ART-associated weight gain and the clinical relevance of this weight gain. As PLHIV survive longer on effective ART, the prevention and management of NAEs will remain a challenge for healthcare providers.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"25 3","pages":"122-132"},"PeriodicalIF":2.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40472441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Alert for polio outbreaks in developed countries. 发达国家脊髓灰质炎疫情警报。

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-01-01 DOI: 10.24875/AIDSRev.M22000054

Vicente Soriano

引用次数: 1

HIV and aging, biological mechanisms, and therapies: What do we know? 艾滋病毒与衰老，生物机制和治疗:我们知道什么?

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-01-01 DOI: 10.24875/AIDSRev.21000085

Tomás M Grosso, José Alcamí, José R Arribas, Marta Martín, Irini Sereti, Philip Tarr, Pedro Cahn, Bonaventura Clotet, Omar Sued, Eugenia Negredo

{"title":"HIV and aging, biological mechanisms, and therapies: What do we know?","authors":"Tomás M Grosso, José Alcamí, José R Arribas, Marta Martín, Irini Sereti, Philip Tarr, Pedro Cahn, Bonaventura Clotet, Omar Sued, Eugenia Negredo","doi":"10.24875/AIDSRev.21000085","DOIUrl":"https://doi.org/10.24875/AIDSRev.21000085","url":null,"abstract":"Aging, a time-dependent loss of physiological function, and its drivers are turning into a significant topic of researchas the population's mean age increases. Epigenetic alterations, telomere shortening or dysfunction, mitogenic stress,oxidative stress, or accumulation of DNA damage can drive the cell to senescence a permanent cell cycle arrest sometimes associated with a secretory phenotype and inflammatory consequences in the surrounding tissue. The amount of senescent cellsgrows over time in older organisms and may induce tissue inflammation and threaten overall tissue homeostasis, favoring aging. Senolytic and senomorphic therapeuticsare an emerging approach to eliminate senescent cells or to block their secretoryphenotypes respectively. Given that people living with HIV suffer non-AIDS comorbidities in a higher prevalence than the general population, aging is accentuated among them. Inflammation biomarkers may be helpful to assess prognosis or act as surrogate endpoints for studies of strategies focused on reversal of HIV-associated accelerated aging. This review summarizes the latest findings in aging and its major drivers, under the light of HIV infection. Since the number of older PLWH is currently rising, it will be of great importance to address and treat their age-related conditions, as well as to better decipher their biological mechanisms.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"25 2","pages":"79-86"},"PeriodicalIF":2.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40639531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The role of nurses in the prevention of anal cancer in HIV-infected men having sex with men - a focus on papillomavirus vaccination and anal cytology screening. 护士在预防感染艾滋病毒的男男性行为者肛门癌中的作用——重点是乳头瘤病毒疫苗接种和肛门细胞学检查。

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-01-01 DOI: 10.24875/AIDSRev.M22000053

Jèssica Muñoz-Rodríguez, Lucia Millán-Revilla

引用次数: 0

COVID-19 vaccination in people living with HIV: current data and perspectives. 艾滋病毒感染者COVID-19疫苗接种:当前数据和观点

IF 2.2 4区医学

AIDS reviews Pub Date : 2022-01-01 DOI: 10.24875/AIDSRev.22000017

Roland Thomas, Jean Cyr Yombi

{"title":"COVID-19 vaccination in people living with HIV: current data and perspectives.","authors":"Roland Thomas, Jean Cyr Yombi","doi":"10.24875/AIDSRev.22000017","DOIUrl":"https://doi.org/10.24875/AIDSRev.22000017","url":null,"abstract":"There is no correlation between HIV per se and other risk factors for severe COVID-19 disease. Pivotal studies have shown that vaccination is one of the effective ways to prevent severe COVID-19 illness in the general population. Studies on people living with HIV (PLWH) are scarce. The majority of these studies with mRNA (BNT126b2 and mRNA-1273) and adenovirus vector (Ad26.COV2.2 and ChAdOx1) vaccines with a low number of patients included shows that PLWH on antiretroviral treatment and with CD4 count > 200/mm³ has a robust immune response. These vaccines are thus effective in preventing severe infection caused by severe acute respiratory syndrome coronavirus 2 in PLWH. However, PLWH with a CD4 count of < 200/mm³ and uncontrolled viral load (VL) seems to have a lower immune response. COVID-19 vaccines are safe in PLWH; adverse effects are mild or moderate, and their incidence is similar to non-HIV people (NHP). The CD4 count decreased significantly and transiently, and the VL rebounded insignificantly in a few patients. A complete vaccination including a third dose is, therefore, recommended. A booster dose with an mRNA vaccine is recommended in PLWH with an advanced stage of their disease.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"24 4","pages":"173-182"},"PeriodicalIF":2.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10831937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0