Zeitschrift fur Erkrankungen der Atmungsorgane最新文献_第5页

[Comparative methodologic studies of closing volume and increase in airway resistance volumes]. [闭合容积与气道阻力容积增加的比较方法学研究]。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

E Dörp, K Maass, S Trekel

引用次数: 0

The influence of intratracheal saline upon the dynamic lung-thorax compliance of premature newborn rabbits. 气管内生理盐水对早产家兔动态肺-胸顺应性的影响。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

A Oddoy, S Renner, O D Saugstad

{"title":"The influence of intratracheal saline upon the dynamic lung-thorax compliance of premature newborn rabbits.","authors":"A Oddoy, S Renner, O D Saugstad","doi":"","DOIUrl":"","url":null,"abstract":"A modern therapy for the respiratory distress syndrome in neonates is the substitution of alveolar surfactant. Supplementary surfactant has to be applied to the lung via an aqueous emulsion. To estimate the effects of fluids instilled into the lungs a total of 144 premature newborn rabbits were used. They were delivered by hysterotomy after 27, 28 or 29 gestational days (term = 31 +/- 1 days; mean +/- SD), anaesthetized (0.5 mg ethylurethane/kg b.w.), paralyzed (1 mg pancuronium bromide/kg b.w.) and ventilated by positive pressure (P = 25 hPa; f = 40/min; I:E = 1:1) with 100% oxygen. By means of body-plethysmography the tidal volume (VT) was recorded before and regularly during 90 min after the application of 0 (controls), 5, 10 or 20 ml saline (0.9% NaCl solution) per kg b.w. intratracheally. Dynamic lung-thorax compliance (Crs) was calculated as VT/P and related to the body weight. The initial Crs values (mean +/- SD) were 0.06 +/- 0.02 (27 days), 0.62 +/- 0.52 (28 days) and 1.08 +/- 0.21 (29 days) ml/hPa/kg, respectively (p less than 0.001). Intratracheal saline application had no detectable effect on Crs in rabbit neonates on day 27 of gestation. On day 28 or 29 of gestation there was a transient (approximately 15 min) Crs reduction, increasing with the volume of applied liquid. At a given saline quantity the severity of Crs reduction depended more on the magnitude of the initial Crs values than on the gestational day.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":76840,"journal":{"name":"Zeitschrift fur Erkrankungen der Atmungsorgane","volume":"177 3","pages":"144-50"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12972076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In situ hybridization. Principles and applications in pathology. 原位杂交。病理学原理及其应用。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

H Mullink

引用次数: 0

Functional morphology of the tracheobronchial tree and the lung periphery. 气管支气管树和肺外周的功能形态学。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

H Eckert

引用次数: 0

[Bronchoalveolar lavage in systemic scleroderma and systemic lupus erythematosus--differential cell values and enzyme cytochemistry]. [系统性硬皮病和系统性红斑狼疮的支气管肺泡灌洗-细胞值和酶细胞化学的差异]。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

C Witt, H Eckert, A Brenke, H Renner, F Hiepe

引用次数: 0

[Prednisolone-dependent asthma patients--often under-treated in ambulatory care? Results of a retrospective study]. [强的松龙依赖哮喘患者-经常在门诊治疗不足?]回顾性研究的结果]。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

R Förster

{"title":"[Prednisolone-dependent asthma patients--often under-treated in ambulatory care? Results of a retrospective study].","authors":"R Förster","doi":"","DOIUrl":"","url":null,"abstract":"A retrospective descriptive analysis of 140 asthmatic patients, classified in our hospital as corticosteroid dependent and treated in outpatients departments showed, that 63% received slow release theophylline (SRT). 33% of them were within the therapeutic dose range, 44% did tolerate a further dose increase of SRT and 23% showed signs of intoxication which could be reduced by decreasing the dose. 12% of all patients were not on oral or inhaled corticosteroids at all. Only 52% received a combined antiasthmatic treatment including corticosteroids and both slow release theophylline and beta-agonists. This percentage was reduced to 18% if secretolytics are counted as a part of combination therapy. During hospital treatment it became evident that actually only 3% of all patients did not tolerate Theophylline retard due to side effects. In hospital 94% of all 140 patients received combined treatment (SRT, beta-agonists and corticosteroids). All of them showed a clear-cut improvement of major asthma symptoms (PEF monitoring, symptom scores, consumption of additional bronchodilators). It is concluded, that steroid dependent asthmatic out-patients are often undertreated: a minor part does not receive steroids at all; about one half does not receive drug therapy combined with bronchodilators; 67 per cent of the patients, who receive SRT (about 2/3 of the total number) is not under optimal theophylline dose regimen.","PeriodicalId":76840,"journal":{"name":"Zeitschrift fur Erkrankungen der Atmungsorgane","volume":"177 1-2","pages":"96-102"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12972073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Bronchoalveolar lavage--a diagnostic method in chronic nonspecific bronchopulmonary diseases in childhood? 2. Studies of cellular and humoral parameters in BAL irrigation fluid]. 支气管肺泡灌洗——儿童慢性非特异性支气管肺疾病的诊断方法?2. BAL灌洗液中细胞和体液参数的研究[j]。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

J Hein, E Martens, I Bauer, P Dörfling, J Brock, H U Gülzow, K Breuel, I Rudolph

引用次数: 0

[Serum reactivity of antigen fractions of atypical mycobacteria in patients with lung diseases]. [肺部疾病患者非典型分枝杆菌抗原组分的血清反应性]。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

H Reutgen, J Pokorny, R Christ, E Ritzau

{"title":"[Serum reactivity of antigen fractions of atypical mycobacteria in patients with lung diseases].","authors":"H Reutgen, J Pokorny, R Christ, E Ritzau","doi":"","DOIUrl":"","url":null,"abstract":"In connection with studies on the pathogenesis of sarcoidosis antigen fractions were isolated from 8 mycobacteria species, three out of each strain. These fractions were tested for their reactivity to serum antibodies by means of RIA-technique, using 40 selected sera from controls, and patients with sarcoidosis, tuberculosis and asthma. Comparing the results (average titer steps) sera from asthmatics showed the lowest and those from sarcoidosis patients the highest reactivities to the mycobacterial antigen fractions. The reactivities clearly differed in dependence on the mycobacteria species. The highest mean reactivity in sarcoidosis patients was found with the HIP-antigen fraction of M. xenopi. It was 8 times higher compared to the control sera as well as the tuberculosis sera and 32 times higher than that of the asthma sera. There were also clear differences in the reactivities within the sarcoidosis sera tested. In sera from patients with clinically inactive sarcoidosis there were found nearly the same or only slightly higher titer steps than in control sera as well as tuberculosis sera, however in clinically active sarcoidosis the titer steps were clearly elevated. The findings are seen in connection with the role of atypical mycobacteria (MOTT) in the pathogenesis of sarcoidosis. The potential applications of the HIP- and Triton X-100 antigen fractions for in vitro diagnostics are discussed.","PeriodicalId":76840,"journal":{"name":"Zeitschrift fur Erkrankungen der Atmungsorgane","volume":"177 1-2","pages":"103-10"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12969875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clinical and histomorphologic findings in Wegener's granulomatosis]. [韦格纳肉芽肿病的临床和组织形态学表现]。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

P Fischer, H Eckert

引用次数: 0

[Factors affecting correct use of metered dose aerosols]. [影响正确使用计量气溶胶的因素]。

Zeitschrift fur Erkrankungen der Atmungsorgane Pub Date : 1991-01-01

A Sprossmann, F Kutschka, M Enk, K C Bergmann

引用次数: 0