[Bronchoalveolar lavage--a diagnostic method in chronic nonspecific bronchopulmonary diseases in childhood? 2. Studies of cellular and humoral parameters in BAL irrigation fluid].

J Hein, E Martens, I Bauer, P Dörfling, J Brock, H U Gülzow, K Breuel, I Rudolph
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Abstract

With a view of the pathogenesis of chronic bronchopulmonary diseases the interrelations between infections and evolving defense system are of interest, they are perhaps detectable by means of diagnostic bronchoalveolar lavage. We carried out cytodifferentiation, investigated adenosine deaminase activities and interleukin 1 formation of macrophages, determined immunoglobulin concentrations (secretory IgA), lysozyme, alpha 2-macroglobulin, alpha 1-antitrypsin, albumin. Because the cytodifferentiation yields insight into topical inflammatory reactions, shows diagnostic useful informations in single cases and because it is simple to carry out we can recommend it for each bronchological examination. There were no results specific for any disease group for parameters mentioned above.

支气管肺泡灌洗——儿童慢性非特异性支气管肺疾病的诊断方法?2. BAL灌洗液中细胞和体液参数的研究[j]。
鉴于慢性支气管肺疾病的发病机制,感染和进化的防御系统之间的相互关系是感兴趣的,它们可能通过诊断支气管肺泡灌洗来检测。我们进行了细胞分化,研究了巨噬细胞的腺苷脱氨酶活性和白细胞介素1的形成,测定了免疫球蛋白浓度(分泌IgA)、溶菌酶、α 2-巨球蛋白、α 1-抗胰蛋白酶、白蛋白。由于细胞分化可以深入了解局部炎症反应,在单个病例中显示诊断有用的信息,并且因为它简单易行,我们可以推荐在每次支气管检查中使用它。对于上述参数,没有特定于任何疾病组的结果。
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