{"title":"Retinal pigment epithelial detachments in the elderly.","authors":"A C Bird, J Marshall","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 6) ","pages":"674-82"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14438653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Deschênes, D H Char, W Freeman, R Nozik, M Garovoy
{"title":"Uveitis: lymphocyte subpopulation studies.","authors":"J Deschênes, D H Char, W Freeman, R Nozik, M Garovoy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recent advances in cellular immunology have enabled us to delineate numerous lymphocyte subsets and activation stages using monoclonal antibody techniques. lymphocyte subsets and activation stages using monoclonal antibody techniques. We have used a fluorescence activated cell sorter (FACS) and newer monoclonal antibodies to study lymphocyte subpopulations and activation stages of T lymphocytes in intraocular fluids and peripheral blood of uveitis patients. T lymphocytes predominated in aqueous and vitreous. A statistically significant correlation was observed between the T lymphocyte subsets in aqueous and peripheral blood. No correlation was seen between the intravitreal lymphocyte subsets and peripheral blood. Many intraocular lymphocytes are present in the aqueous secondary to a blood ocular barrier breakdown. Using an anti-interleukin-2 (IL-2) receptor monoclonal antibody as a marker for T-cell activation, activated lymphocytes were found in intraocular and peripheral blood of both idiopathic and non-idiopathic uveitis. A statistically significant correlation was found between in vivo lymphocyte activation and clinical uveitis activity. In uveitis, lymphocyte activation in the eye paralleled levels found in the blood. Systemic and intraocular lymphocyte activation occurs in both idiopathic uveitis as well as in systemic syndromes associated with intraocular inflammation. It is possible that idiopathic uveitis is a systemic disease.</p>","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 2) ","pages":"246-51"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14614924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathogenesis of recurrent corneal erosion: a further aetiological factor?","authors":"G E Rose, M J Lavin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An unmasked, prospective study of the magnitude of Bell's phenomenon in 42 patients with recurrent corneal epithelial erosion has demonstrated an abnormally high prevalence of 'absent' or 'weak' Bell's phenomenon as compared to that in a control group of 189 patients. Those patients without a predisposing factor had a 78 per cent prevalence of abnormal Bell's phenomenon, those with an epithelial or basement membrane dystrophy had a 55 per cent prevalence, whereas those with preceding traumatic corneal abrasion formed an intermediate group (62 per cent abnormal Bell's phenomenon); the prevalence of 'absent' or 'weak' Bell's phenomenon in the control group was 26 per cent. The probable mechanisms of recurrent corneal epithelial erosion are discussed in the light of this newly described association.</p>","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 4) ","pages":"453-6"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14615197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Senile cataract and senile macular degeneration: an investigation into possible risk factors.","authors":"J M Gibson, D E Shaw, A R Rosenthal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Data from the Melton Mowbray Eye Study and Community Health Study have been used to look for possible risk factors for senile cataract and senile macular degeneration. Significant associations with senile cataract were age, female sex, myopia, social class and antihypertensive treatment, whilst for senile macular degeneration age and the absence of arcus senilis were significant. These observations are presented and discussed in relation to findings from other studies.</p>","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 4) ","pages":"463-8"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14615198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cicatrizing conjunctivitis.","authors":"P Wright","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 1) ","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14643266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial conjunctivitis.","authors":"J I McGill","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 1) ","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14644079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computer automated visual acuity testing for visual screening.","authors":"D Wong, A Plumb","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A computer program was designed for automated visual acuity testing, the aim of which was to evaluate the effectiveness of such systems in a busy out-patient department. The time required for explanation and performing the automated test was compared with that taken by nurses measuring visual acuities in the conventional manner using a Snellen's chart. The correlation of the results of the computer system and the manual measurements was tested.</p>","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 4) ","pages":"498-503"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14660455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapy for ocular bacterial infection.","authors":"J Baum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper presents in large part the author's views on the treatment of a variety of bacterial infections of the eye. Emphasis is placed on the management of bacterial corneal ulcers and endophthalmitis.</p>","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 1) ","pages":"69-77"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14583364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brow suspension in the management of ptosis: an analysis of over 100 cases.","authors":"E G Kemp, C R James, J R Collin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study analyses the management of ptosis associated with minimal levator function in 105 cases over an eight-year period. A 96 per cent success rate has been recorded which parallels previous authors' results. Clinical indications and relevant pathology are detailed with early identification and graded operative intervention postulated as suitable management for most cases. The overall success rate depended on the use of autogenous fascia lata, delaying its use until after the age of four, and adopting a bilateral approach whenever possible. Stored fascia lata was used in infants and in certain acquired unilateral cases.</p>","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 1) ","pages":"84-7"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14583368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thermal effects on the trabecular meshwork induced by laser irradiation: clinical implications deduced from ultrastructural studies on the macaca speciosa monkey.","authors":"F Fankhauser, E Van der Zypen, S Kwasniewska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The pressure lowering effect brought about by irradiating the chamber angle with argon laser light according to Wise and Witter was studied by ultrastructural methods and was analysed in order to ascertain the mechanism responsible. To this end, the effects induced in 4 macaca speciosa monkeys by such irradiation were examined using scanning and transmission electron microscopy. It was noted that the phenomena observed depend critically on the precise location of the irradiation site. When the anterior trabecular meshwork is irradiated, a proliferation of monocellular, atypical corneal endothelium cells occurs which tightly surround the irradiation location. In irradiation of the posterior trabecular meshwork, however, this effect is much less prominent. In both cases, by the end of the twelfth week a progressive, lytic degeneration of the entire trabecular meshwork was observed which reached the inner wall of Schlemm's canal.</p>","PeriodicalId":76757,"journal":{"name":"Transactions of the ophthalmological societies of the United Kingdom","volume":"105 ( Pt 5) ","pages":"555-61"},"PeriodicalIF":0.0,"publicationDate":"1986-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14589664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}