{"title":"Injuries and poisonings in out-of-home child care and home care.","authors":"W. Gunn, P. Pinsky, J. Sacks, L. Schonberger","doi":"10.1001/ARCHPEDI.1991.02160070075025","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070075025","url":null,"abstract":"As part of a national telephone survey regarding health events associated with out-of-home child care, data regarding poisonings and injuries were collected. Of 171 reported poisonings, none occurred during out-of-home child care. The rate of injury during out-of-home child care was 1.69 per 100,000 child-hours compared with 2.66 for home care. Overall injury rates were slightly higher for children who attended out-of-home child care than for those who do not. This occurred because children who attended out-of-home child care had a higher injury rate during home care than did the children who did not attend out-of-home child care at all. Although out-of-home child care may carry an increased risk of infectious disease relative to home care, it does not appear to carry an increased risk of injury and, in fact, may confer a lower risk.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"26 1","pages":"779-81"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85841152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Roberts, C. Szelc, S. Scates, M. T. Boyd, K. Soderstrom, M. W. Davis, J. Glaspy
{"title":"Neutropenia in an extremely premature infant treated with recombinant human granulocyte colony-stimulating factor.","authors":"R. Roberts, C. Szelc, S. Scates, M. T. Boyd, K. Soderstrom, M. W. Davis, J. Glaspy","doi":"10.1001/ARCHPEDI.1991.02160070104030","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070104030","url":null,"abstract":"Neutropenia in the newborn is often associated with sepsis, maternal hypertension, or prematurity. We describe a 654-g infant born at 30 weeks' gestation by cesarean section due to severe maternal hypertension. His course was complicated by five episodes of sepsis, including three with group B streptococcus. The results of hematologic and immunologic studies were normal except that absolute neutrophil counts were low (less than 1 x 10(9)/L) with intermittent increases during sepsis. Human recombinant granulocyte colony-stimulating factor administered subcutaneously (10 micrograms/kg per day initially) resulted in an absolute neutrophil count of greater than 30 x 10(9)/L within 2 weeks. The dosage was lowered and the absolute neutrophil counts were maintained at 8 to 12 x 10(9)/L with no further septic episodes. The human recombinant granulocyte colony-stimulating factor therapy was discontinued after 7 months, and the patient remained healthy with an absolute neutrophil count of greater than 2 x 10(9)/L. Thus, treatment with human recombinant granulocyte colony-stimulating factor may be useful as a temporary measure for neonatal neutropenia associated with sepsis. A controlled, clinical trial is warranted.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"8 1","pages":"808-12"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84696784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Black, J. Cherry, H. Shinefield, B. Fireman, P. Christenson, D. Lampert
{"title":"Apparent decreased risk of invasive bacterial disease after heterologous childhood immunization.","authors":"S. Black, J. Cherry, H. Shinefield, B. Fireman, P. Christenson, D. Lampert","doi":"10.1001/ARCHPEDI.1991.02160070042019","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070042019","url":null,"abstract":"To investigate the possibility that there might be an increased risk of heterologous invasive bacterial disease after routine childhood immunization with measles, mumps, and rubella vaccine live; diphtheria and tetanus toxoids and pertussis vaccine; and oral poliovirus vaccine live, a case-control study was conducted within the Kaiser Permanente Northern California pediatric population. Contrary to the premise, an apparent protective effect against invasive bacterial disease was detected after all childhood vaccinations. However, when adjustment was made for frequency of well-care visits and day-care attendance, no significant relationship was seen between receipt of routine childhood immunizations and risk of invasive heterologous bacterial disease for any individual vaccine, although a statistically significant protective effect was detected within 1 or 3 months after the receipt of any vaccine. Since a decreased risk of invasive bacterial disease was also noted to be related to the receipt of routine well-child pediatric care, other preventive health care measures may be responsible for the apparent immunization protective effect.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"259 1","pages":"746-9"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75392364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dose-related immunogenicity of Haemophilus influenzae type b capsular polysaccharide-Neisseria meningitidis outer membrane protein conjugate vaccine.","authors":"V. Wong, R. Quagliata, R. Adler, K. Kim","doi":"10.1001/ARCHPEDI.1991.02160070038018","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070038018","url":null,"abstract":"We studied the immunologic responsiveness to Haemophilus influenzae type b capsular polysaccharide-Neisseria meningitidis group b outer membrane protein conjugate vaccine (PRP-NOMP) in children 2 to 42 months of age with vaccine dosages containing 7.5, 15, or 30 micrograms of PRP. Overall, PRP-NOMP was highly immunogenic. Geometric mean titers of anti-PRP antibody increased from 0.09 to 3.3 mg/L and 6.6 mg/L following each dose of vaccine, respectively, in the 2- to 18-month age group. Similarly, anti-PRP antibody geometric mean titers increased from 0.12 to 5.9 mg/L in the older than 18-month age group. However, we noted an apparent inverse relationship between vaccine dosages and immune responses following two doses of PRP-NOMP in 2- to 18-month-old children. Anti-PRP antibody geometric mean titers were 12.0, 6.9, and 3.5 mg/L, respectively, after the second dose of vaccine containing 7.5, 15, or 30 micrograms of PRP. Additional studies are needed to understand the mechanisms responsible for this inverse relationship and also to determine the optimal dosage of PRP-NOMP for young children.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"47 1","pages":"742-5"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78683185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Blanchette, H. Hume, Levy Gj, N. Luban, R. Strauss
{"title":"Guidelines for auditing pediatric blood transfusion practices.","authors":"V. Blanchette, H. Hume, Levy Gj, N. Luban, R. Strauss","doi":"10.1001/ARCHPEDI.1991.02160070083027","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070083027","url":null,"abstract":"Although transfusion of blood products is an essential and potentially life-saving measure, not all blood transfusions are beneficial to patients. The associated risks, particularly transfusion-transmitted viral illnesses, such as hepatitis and acquired immunodeficiency syndrome, require that careful consideration be given before a decision is made to transfuse any blood product. Many institutions have established a local committee to monitor transfusion practices and audit such practices regularly. To assist in this task, the Pediatric Hemotherapy Committee of the American Association of Blood Banks has developed guidelines for the conduct of pediatric blood transfusion audits. These guidelines, summarized herein, cover transfusion of red blood cells, platelets, white blood cells, fresh-frozen plasma, albumin, and clotting concentrates. The use of cytomegalovirus low-risk and irradiated blood products is also discussed. Throughout the report, special attention is given to the transfusion needs of newborn infants.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"9 1","pages":"787-96"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77640931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Puncture wound-induced Achromobacter xylosoxidans osteomyelitis of the foot.","authors":"D. M. Hoddy, L. Barton","doi":"10.1001/ARCHPEDI.1991.02160060015006","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160060015006","url":null,"abstract":"Sir . —Achromobacter xylosoxidans is a gram-negative bacteria, found in the vertebrate intestinal tract and isolated from aqueous environments. The majority of infections caused by A xylosoxidans are either nosocomially acquired or involve immunocompromised hosts, but sporadic communityacquired infections in presumed normal patients have been described. 1 Osteomyelitis of the foot following puncture wounds through sneakers is most often associated with Pseudomonas aeruginosa or other Pseudomonas species. 2-4 We describe a child with community-acquired A xylosoxidans osteomyelitis of the foot that resulted from a puncture wound. Patient Report .—A previously healthy 11-year-old boy stepped on two nails 2.5 weeks before seeking care. The nails penetrated his tennis shoe to a presumed depth of about 2 inches. Immediately after the injury, the foot was soaked in hydrogen peroxide and alcohol. The wounds initially appeared to be healing well without evidence of drainage, pain, or swelling. In the week before admission the child","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"7 1","pages":"599-600"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84359793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Little, L. Snell, C. Rosenfeld, L. Gilstrap, N. Gant
{"title":"Failure to recognize fetal alcohol syndrome in newborn infants.","authors":"B. Little, L. Snell, C. Rosenfeld, L. Gilstrap, N. Gant","doi":"10.1097/00006254-199105000-00011","DOIUrl":"https://doi.org/10.1097/00006254-199105000-00011","url":null,"abstract":"A clinically distinct constellation of major and minor anomalies, termed the fetal alcohol syndrome, occurs among infants whose mothers abuse alcohol during pregnancy. In addition, significantly higher rates of pregnancy complications, including perinatal deaths and fetal growth retardation, occur among these women and their offspring. We studied the medical records of 40 infants born to 38 alcohol abusers and the frequency of characteristics associated with fetal alcohol syndrome. Physical examinations of 6 infants revealed primary features consistent with a diagnosis of fetal alcohol syndrome. Postnatal growth and development were very poor in 17 (50%) of 34 liveborn alcohol-exposed infants. The diagnosis of fetal alcohol syndrome did not appear in the medical records of any of these infants despite the fact that the mothers' obstetric records included a history of alcohol abuse during pregnancy. This finding emphasizes the importance of good communication between obstetric and pediatric medical staff at this hospital, particularly when providing care for pregnant women and newborn infants at high risk for complications due to maternal alcohol or other drug abuse.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"51 1","pages":"1142-6"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79811068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Far from the ideal. The plight of poor children in the United States.","authors":"V. Fulginiti","doi":"10.1001/ARCHPEDI.1991.02160050013001","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160050013001","url":null,"abstract":"The child on the cover of this month's issue ofAJDCwas visualized as an ideal by an unknown painter in colonial times. The child is beautiful, well nourished, placid, and obviously well cared for. This is the ideal that many think of when asked to picture our aspirations for our children. Unfortunately, in the United States today, we fall far short of providing that ideal for millions of infants, children, adolescents, and young adults. This issue ofAJDCis devoted to exploring the dimensions of and reasons for the problems as well as offering potential corrective actions that might be applied to the plight of our underserved or unserved youth. We embarked on this issue as part of the family of American Medical Association journals' efforts to highlight what has become a national disgrace: 47 000 000 or more individuals are neglected at a time when many in the","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"57 1","pages":"489-90"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85824801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Allison, C. Stephenson, T. Angtuaco, C. Glasier, B. Wood
{"title":"Radiological case of the month. Tuberous sclerosis with myocardial and central nervous system involvement at birth.","authors":"J. Allison, C. Stephenson, T. Angtuaco, C. Glasier, B. Wood","doi":"10.1001/ARCHPEDI.1991.02160040133022","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160040133022","url":null,"abstract":"","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"69 1","pages":"471-2"},"PeriodicalIF":0.0,"publicationDate":"1991-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86141263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}