American journal of diseases of children最新文献_第6页

A comparative trial of the reactogenicity and immunogenicity of Takeda acellular pertussis vaccine combined with tetanus and diphtheria toxoids. Outcome in 3- to 8-month-old infants, 9- to 23-month-old infants and children, and 24- to 30-month-old children. 武田无细胞百日咳疫苗与破伤风、白喉类毒素联合疫苗反应原性和免疫原性的比较研究。3- 8个月婴儿、9- 23个月婴儿和儿童以及24- 30个月儿童的结局。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070030017

M. Kimura, H. Kuno-sakai, Y. Sato, H. Kamiya, R. Nii, S. Isomura, K. Horiuchi, T. Kato, M. Deguchi, H. Saikusa

{"title":"A comparative trial of the reactogenicity and immunogenicity of Takeda acellular pertussis vaccine combined with tetanus and diphtheria toxoids. Outcome in 3- to 8-month-old infants, 9- to 23-month-old infants and children, and 24- to 30-month-old children.","authors":"M. Kimura, H. Kuno-sakai, Y. Sato, H. Kamiya, R. Nii, S. Isomura, K. Horiuchi, T. Kato, M. Deguchi, H. Saikusa","doi":"10.1001/ARCHPEDI.1991.02160070030017","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070030017","url":null,"abstract":"The reactogenicity and immunogenicity of the Takeda acellular pertussis vaccine combined with tetanus and diphtheria toxoids were compared in 139 infants aged 3 to 8 months, 60 infants and children aged 9 to 23 months, and 99 children aged 24 to 30 months. Good antibody responses to pertussis toxin (PT), filamentous hemagglutinin (FHA), and agglutinogens occurred in all age groups after both the third and fourth doses. After the fourth (booster) dose, the mean antibody values in initially seronegative infants vaccinated at 3 to 8 months of age were as follows: anti-PT, 67.8 enzyme-linked immunosorbent assay units (EU) per milliliter; anti-FHA, 149.5 EU/mL; the agglutinin titer was 125.6. The values in initially seronegative children vaccinated at 24 to 30 months of age were as follows: anti-PT, 92.9 EU/mL; anti-FHA, 251.7 EU/mL; the agglutinin titer was 275.8. Reactions following immunization were minimal. Except for drowsiness after the first dose in infants, there were no clinically significant differences in reactions between infants and older children. The findings in this study coupled with the recent demonstration of efficacy of this vaccine in 2-year-old children supports the recent Japanese recommendation to lower the age of immunization with acellular pertussis vaccine combined with tetanus and diphtheria toxoids to 3 months.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"2 1","pages":"734-41"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76185009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 69

Seasonal variation in growth during growth hormone therapy. 生长激素治疗期间生长的季节性变化。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070065023

M. Rudolf, Z. Zadik, S. Linn, Z. Hochberg

{"title":"Seasonal variation in growth during growth hormone therapy.","authors":"M. Rudolf, Z. Zadik, S. Linn, Z. Hochberg","doi":"10.1001/ARCHPEDI.1991.02160070065023","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070065023","url":null,"abstract":"Seasonal variation in growth of normal children has been well described, although the mechanism by which it occurs has not been elucidated. The growth of 52 growth hormone-deficient children treated with synthetic human growth hormone was analyzed. A similar seasonal variation was observed, with mean (+/- SEM) peak growth occurring in the summer (8.2 +/- 0.3 cm/y) and winter (7.7 +/- 0.2 cm/y), and trough growth occurring in the autumn (6.9 +/- 0.3 cm/y). Forty-seven percent of subjects grew minimally during the autumn, and only two children showed peak growth in that season. Individual variations between maximal and minimal growth seasons amounted to 3.5 +/- 0.3 cm/y. The seasonal pattern was statistically significant for the group as a whole, for the prepubertal subgroup, and for the boys. The variation persisted when the first year of treatment was excluded to avoid bias of the initial growth spurt. The season of onset of therapy did not affect total growth during the first year. The demonstration of a seasonal pattern in growth of these children suggests that the seasonal variation may be mediated by peripheral rather than central factors. Paired clonidine-provoked growth hormone levels and an integrated concentration of 24-hour growth hormone levels and serum levels of insulinlike growth hormone I measured in a control group of normally growing children were also analyzed and showed no seasonal variation. This further suggests that peripheral rather than central factors are responsible for the seasonal variation in children's growth.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"31 1","pages":"769-72"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88716937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 45

Effect of necrotizing enterocolitis on urinary epidermal growth factor levels. 坏死性小肠结肠炎对尿表皮生长因子水平的影响。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070100029

Susan M. Scott, Cathy Rogers, Pamela Angelus, Conra Backstrom

引用次数: 55

Objective structured clinical examination in a pediatric residency program. 目的:对儿科住院医师进行结构化临床检查。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070053021

B. Joorabchi

{"title":"Objective structured clinical examination in a pediatric residency program.","authors":"B. Joorabchi","doi":"10.1001/ARCHPEDI.1991.02160070053021","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070053021","url":null,"abstract":"This report describes and evaluates a 42-station objective structured clinical examination (OSCE) administered to 29 pediatric residents and six medical students. In half of the stations, residents spent 5 minutes performing a clearly defined clinical task while being rated by an observer. In the other half of the stations, they answered questions based on the data just gathered. There were six interviews with real or simulated patients, four physical examinations, six laboratory tests or procedures, and one chart review. Eight rest stops were provided. The results of the OSCE were compared with those of resident performance ratings and the Pediatric Board's in-training examination. The OSCE scores could clearly separate the students from the residents and each class of residents from all others (construct validity). The in-training examination could not separate first-year post-graduate level and second-year postgraduate level residents. Resident performance ratings could distinguish only first-year postgraduate level from third-year postgraduate level residents. Residents uniformly agreed that the OSCE measured important clinical objectives attesting to its content validity. Reliability for the OSCE was calculated at the 0.8 to 0.83 range. It is concluded that valid and reliable clinical examinations in pediatrics are feasible, practical, and highly desirable.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"172 1","pages":"757-62"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77524566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 70

Effects of obesity on aerobic fitness in adolescent females. 肥胖对青春期女性有氧适能的影响。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070060022

T. Rowland

{"title":"Effects of obesity on aerobic fitness in adolescent females.","authors":"T. Rowland","doi":"10.1001/ARCHPEDI.1991.02160070060022","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1991.02160070060022","url":null,"abstract":"Obesity impairs performance in most athletic events, but the influence of increased body fat on cardiopulmonary function has not been clearly delineated. An understanding of the fatness-fitness relationship is important in the optimal design of exercise programs for obese subjects. In this study, 27 adolescent females with body fat levels ranging from normal to gross obesity were evaluated to determine the impact of adiposity on physiologic factors during maximal and submaximal treadmill walking. Increased skinfold measures correlated significantly with absolute maximal oxygen uptake throughout the range of body fat levels (r = .72), and oxygen consumption per kilogram of body weight and treadmill endurance time both declined as fatness increased (r = -.49 and -.42, respectively). Obesity did not affect submaximal walking economy. These findings indicate that increased fat levels are associated with increased cardiopulmonary exercise capacity, but that functional fitness declines because of the inert load created by excess body fat. Therefore, therapeutic exercise programs for obese adolescents are best designed to increase caloric expenditure and decrease body fat rather than to improve aerobic fitness.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"32 1","pages":"764-8"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84236703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 125

Predictors of neurodevelopmental outcome following bronchopulmonary dysplasia. 支气管肺发育不良后神经发育结局的预测因素。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070109031

Jean M. Luchi, Forrest C. Bennett, J. C. Jackson

引用次数: 40

Saving money with home care. 通过家庭护理节省开支。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070021014

R. Schoumacher

引用次数: 2

Home care cost-effectiveness for respiratory technology-dependent children. 依赖呼吸技术儿童的家庭护理成本效益。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070025016

A. I. Fields, A. Rosenblatt, M. Pollack, J. Kaufman

引用次数: 77

The fallacy of the hemorrhagic shock and encephalopathy syndrome. 失血性休克和脑病综合征的谬论。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070012003

M. Bass

引用次数: 3

War souvenir poisoning. 战争纪念品中毒。

American journal of diseases of children Pub Date : 1991-07-01 DOI: 10.1001/ARCHPEDI.1991.02160070018011

E. Secord, S. Claude, C. Newton

引用次数: 18