{"title":"Why wait for DTP-E-IPV?","authors":"E. Marcuse","doi":"10.1001/ARCHPEDI.1989.02150210031012","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150210031012","url":null,"abstract":"","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"68 1","pages":"1006-7"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88120862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clear heads and bayesian tales: predictive value and the coin toss?","authors":"R. D. Mauro","doi":"10.1001/archpedi.1989.02150210017009","DOIUrl":"https://doi.org/10.1001/archpedi.1989.02150210017009","url":null,"abstract":"In Reply .—Dr Mauro's remarks would be very pertinent if we had suggested in our reply that platelet antibodies should be detected as part of a screening program of ITP in the general population . This is not so, however. Such a screening test would be unjustifiable, not only because of its immense costs, but mainly because it would offer no therapeutic or preventive advantage to the patients detected in this manner, as compared with those whose thrombocytopenia has been discovered, as is usually the case, on clinical grounds. Thus, the controversy regarding the utility of platelet antibody testing is limited to the population of patients with thrombocytopenia and cannot be extrapolated to the general population. In this setting, our statement on \"coin flipping\" remains correct. Platelet antibody testing has a positive predictive value for ITP of 50%. In other words, the probability for a patient with thrombocytopenia of having ITP if the","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"3 1","pages":"1000-1"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87389966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computers in medicine. Augmenting medical care in pediatric patients with chronic illnesses.","authors":"E. Handler","doi":"10.1001/ARCHPEDI.1989.02150210047016","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150210047016","url":null,"abstract":"The use of computers to aid care for chronically ill pediatric patients is a relatively new concept. We are currently using Filemaker II software and a Macintosh Plus computer to augment overall patient care in children with chronic diseases, such as spina bifida, cerebral palsy, neuromuscular diseases, head injury, and spinal cord injury. This is a computerized medical record with a clinical database for dissemination of information to multidisciplinary team members, generating letters to private health care providers, displaying telephone messages, and assisting inpatient care. Advances in computer technology will provide future applications to aid health care providers in caring for patients with chronic illnesses.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"39 1","pages":"1021-3"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88392804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cynthia C. See, L. Newman, S. Berezin, M. Glassman, M. Medow, A. Dozor, S. Schwarz
{"title":"Gastroesophageal reflux-induced hypoxemia in infants with apparent life-threatening event(s).","authors":"Cynthia C. See, L. Newman, S. Berezin, M. Glassman, M. Medow, A. Dozor, S. Schwarz","doi":"10.1001/ARCHPEDI.1989.02150200111028","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150200111028","url":null,"abstract":"To evaluate relationships between gastroesophageal reflux (GER) and the development and onset of apparent life-threatening event(s) (ALTE), 16 infants presenting with ALTE and 6 control subjects manifesting clinical GER alone were studied using prolonged, esophageal pH monitoring in conjunction with simultaneous pulse oximetry and transthoracic impedance pneumocardiography. Despite the absence of a clinical vomiting history in 14 of 16 patients with ALTE, the incidence of GER was similar in both groups (patients with ALTE vs control subjects, 95% vs 100%). Significant arterial oxygen desaturation (less than 90% for greater than 3 minutes) was monitored during 60 episodes in 14 of 16 infants with ALTE, compared with no episodes of reduced arterial oxygen saturation in control subjects. Fifty-four of 60 of these desaturation events commenced within 3.9 +/- 0.4 minutes (mean +/- SD) of onset of a drop in esophageal pH to less than 4.0. Linear regression analysis indicates a significant correlation between duration of esophageal acidification and length of individual hypoxemic episodes (r = .39). Pneumocardiograms were normal in all patients. These data suggest that unsuspected GER is common in infants presenting with ALTE and, in these patients, GER may be directly associated with reflex hypoxemic episodes. Prolonged intraesophageal pH monitoring, performed simultaneously with evaluation for apnea, should be considered in all infants presenting with ALTE.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"124 1","pages":"951-4"},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87974927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic sinusitis. The disease of all ages.","authors":"G. Rachelefsky","doi":"10.1001/ARCHPEDI.1989.02150200030013","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150200030013","url":null,"abstract":"Sinusitis is one of the most frequently overlooked and poorly understood diseases of childhood. There is a lack of information regarding criteria for diagnosis and the most effective method of management of sinusiSee also p 938. tis in children. Controversy exists regarding whether a sinus cavity is infected, how to diagnose sinusitis, and what the best treatment choice and duration is. The article by Tinkelman and Silk 1 in this issue of AJDC has prompted this editorial to bring the pediatrician up to date regarding these issues. I will limit my remarks to chronic sinusitis, that is, compatible symptoms that have been present for at least 3 weeks. (Some experts in the field would shorten this time to 10 days. 2,3 ) The nasal sinuses are four paired structures: the maxillary, ethmoidal, sphenoidal, and frontal sinuses that develop as evaginations of the mucous membranes of the nasal meatuses. The origin of","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"14 1","pages":"886-8"},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81662685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susan M. Kegeles, Nancy E. Adler, Charles E. Irwin
{"title":"Adolescents and condoms. Associations of beliefs with intentions to use.","authors":"Susan M. Kegeles, Nancy E. Adler, Charles E. Irwin","doi":"10.1001/ARCHPEDI.1989.02150200063019","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150200063019","url":null,"abstract":"Sexually active adolescents should use condoms to prevent the transmission of sexually transmitted diseases, including human immunodeficiency virus. This study examined, among male and female adolescents, which beliefs about condoms are associated with intentions to use them if they have coitus in the next year. Teenagers attending adolescent health clinics completed self-administered surveys. Although most adolescents knew that condoms prevent sexually transmitted diseases, an increasing belief in the preventive effects of condoms was not associated with an increased motivation to use them. Instead, other immediate, short-term consequences, such as the ease with which they can be used and discomfort associated with their use, were most strongly associated with adolescents' intentions to use condoms. To encourage condom use, messages from physicians and other health care professionals must focus on adolescents' beliefs that are most likely to encourage or inhibit use of condoms. Health considerations should not be the sole emphasis of such communications if the goal is to increase the use of condoms among sexually active adolescents.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"1 1","pages":"911-5"},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80154834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Campylobacter pylori gastritis and peptic ulcer in children.","authors":"B. Dahms, S. Czinn, P. Kilbridge","doi":"10.1001/ARCHPEDI.1989.02150200014004","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150200014004","url":null,"abstract":"In Reply. —Chiesa et al and Oderda et al agree with us regarding the high prevalence of CP infection and its relationship to antral gastritis and duodenal ulcer. The highly effective results of antimicrobial therapy reported by Chiesa et al are interesting. To date, we have en unsuccessful in eradicating CP with amoxicillin monotherapy. Our results are in agreement with recently reported adult studies by Rauws et al, 1 as well as pediatric studies by De Giacomo et al. 2 The latter group had no success in eradicating CP or improving the underlying gastritis in their pediatric patients. The experience cited above by Oderda et al also indicates failure to achieve permanent eradication of the organism with ampicillin. We look forward to the publication of the study done by Chiesa et al. Perhaps we may be able to determine why we and others have not been successful in our efforts to eradicate","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"11 1","pages":"877-8"},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84484875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Eldridge, Martha Bridge Denckla, Ellen Bien, Susan E. Myers, Muriel I. Kaiser-Kupfer, A. Pikus, Sandra Schlesinger, D. M. Parry, James M. Dambrosia, Michael Zasloff, John J. Mulvihill
{"title":"Neurofibromatosis type 1 (Recklinghausen's disease). Neurologic and cognitive assessment with sibling controls.","authors":"R. Eldridge, Martha Bridge Denckla, Ellen Bien, Susan E. Myers, Muriel I. Kaiser-Kupfer, A. Pikus, Sandra Schlesinger, D. M. Parry, James M. Dambrosia, Michael Zasloff, John J. Mulvihill","doi":"10.1001/ARCHPEDI.1989.02150190083027","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150190083027","url":null,"abstract":"Neurologic and cognitive function in neurofibromatosis type 1 (NF1) were assessed in a controlled pilot study of 13 pairs of siblings aged 6 to 27 years. One subject in each pair was affected with NF1, and the other, the control subject, was unaffected. Subjects with evidence of focal central nervous system disease were excluded. The 13 subjects with NF1 had no excess of mental retardation, attention-deficit disorder, or specific learning disorders (using Wilcoxon's Signed Rank Test and McNemar's Test for Symmetry). These subjects, however, had significantly higher scores for subtle neurologic abnormalities (21 vs 6) and significantly lower full-scale IQ scores (94 vs 105) than their unaffected siblings. The IQ scores of the affected subjects were not clustered at the lower end of the scale but showed a slight downward shift in distribution compared with those of their siblings. In addition, a visual-spatial orientation deficit was present in eight of nine affected subjects so evaluated. The findings suggest that subjects with NF1 have a widespread alteration of the brain during development that manifests as one or more specific types of neuropsychologic deficits.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"24 1","pages":"833-7"},"PeriodicalIF":0.0,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87358275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. E. Wilson, J. Weiner, J. Bender, S. Bergstrom, B. Starfield
{"title":"Does a residents' continuity clinic provide primary care?","authors":"M. E. Wilson, J. Weiner, J. Bender, S. Bergstrom, B. Starfield","doi":"10.1001/ARCHPEDI.1989.02150190059021","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150190059021","url":null,"abstract":"Pediatric residents are required to care for a group of children over a period of time. For many, this \"continuity\" experience is in a hospital outpatient department that may or may not provide primary care. We applied a measure of primary care to the Primary Care Clinic, the continuity clinic at The Johns Hopkins Hospital, Baltimore, Md, and found that it compared favorably with private pediatric practices in the Baltimore area, providing significantly more \"principal care\" (93% vs. 84.5% of encounters), and to the Harris Lane Home walk-in clinic, where only 51% of encounters were \"principal care\". The Primary Care Clinic scored higher on a primary care index, a measure of the extent to which the facility serves as a primary care source for patients, suggesting that hospital-based training can provide residents with an opportunity to provide primary care.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"66 1","pages":"809-12"},"PeriodicalIF":0.0,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81115880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adolescence. What is normal?","authors":"D. Offer, E. Ostrov, K. I. Howard","doi":"10.1001/ARCHPEDI.1989.02150180113031","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1989.02150180113031","url":null,"abstract":"We present in some detail what constitutes normal behavior, or mental health, among teenagers. Our data are based on the results of a specially devised psychological questionnaire by one of us (D.O.). This questionnaire has been shown to reliably distinguish mentally healthy from psychiatrically disturbed populations. Results are presented across three decades (1960s, 1970s, and 1980s), across genders, and across the high school years. A conceptual framework is presented to help the clinician working with adolescents to understand the fluctuation in psychopathology among youth. Adolescent density in the total population is shown to be a significant factor in determining the rate of disturbance among teenagers. Our research findings demonstrate that the rate of behavioral disturbance among adolescents is the same as in other parts of the life cycle. The clinician working with adolescents tends to underestimate the severity of adolescent problems because of the near-universal belief that all adolescents undergo \"adolescent turmoil.\" We have found that adolescents who are experiencing turmoil need professional help.","PeriodicalId":7654,"journal":{"name":"American journal of diseases of children","volume":"75 1","pages":"731-6"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85299476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}