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Revista iberica de endocrinologia最新文献

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[Basic principles of radioimmunoanalysis]. 放射免疫分析的基本原理。
Revista iberica de endocrinologia Pub Date : 1976-07-01
P Esbrit, F Mata
{"title":"[Basic principles of radioimmunoanalysis].","authors":"P Esbrit,&nbsp;F Mata","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors review the principal characteristics of radioimmunoassay (R.I.A.), in grounds of the so-called \"saturation analysis\" techniques, which are of increasing interest among the chemical laboratory procedures. They study each element of R.I.A. separatedly, and finally they make a brief display of the different applications of radioimmunoassay stressing its significance in the endocrinological field.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 136","pages":"333-55"},"PeriodicalIF":0.0,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12153903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hormone dependence in functional thyroid cancers, survival after total thyroidectomy combined with radioactive iodine and thyroid extract therapy]. [激素依赖对功能性甲状腺癌的影响，甲状腺全切除术联合放射性碘和甲状腺提取物治疗后的生存率]。
Revista iberica de endocrinologia Pub Date : 1976-07-01
J A Sánchez Martín, J M Linazasoro, S Cifuentes Langa, J M Román Terán
{"title":"[Hormone dependence in functional thyroid cancers, survival after total thyroidectomy combined with radioactive iodine and thyroid extract therapy].","authors":"J A Sánchez Martín,&nbsp;J M Linazasoro,&nbsp;S Cifuentes Langa,&nbsp;J M Román Terán","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors reviewed current criteria on hormone-dependence in functional thyroid cancers, presenting data of compared disease evolution based on the casuistics of thyroid carcinomas from the files of the Fundación Jiménez Díaz, with 5 and 10 year follow-up studies in some of the cases. They found a higher number of survivors among the patients with papilliferous carcinoma in both 5 and 10 year follow-up groups whom, aside total surgical removal of the gland and the administration of thyroid extracts, those who had thyroid residues left were given 100 mc of 131I. Among the patients with follicular adenocarcinoma, under the same comparative conditions, differences were not very clear in the 5 year follow-up group, while the 10 year follow-up group showed marked differences. The authors conclude that an adequate combination of the three therapeutic procedures may allow a higher survival rate.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 136","pages":"385-99"},"PeriodicalIF":0.0,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12155879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Incorporation of 1-C14 palmitic acid into liver lipids of rats in different hormanal states]. [1-C14棕榈酸在不同激素状态大鼠肝脂中的掺入]。
Revista iberica de endocrinologia Pub Date : 1976-07-01
J M De Gandarias, M Lacort, B Fernández, F Ainz, J J Goiriena De Gandarias, S Rabanal, J M Pamo
{"title":"[Incorporation of 1-C14 palmitic acid into liver lipids of rats in different hormanal states].","authors":"J M De Gandarias,&nbsp;M Lacort,&nbsp;B Fernández,&nbsp;F Ainz,&nbsp;J J Goiriena De Gandarias,&nbsp;S Rabanal,&nbsp;J M Pamo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Adrenalectomy and/or cortisol-induced variations in the in vivo and in vitro incorporation of 14C-palmitic acid 1 into the different fractions of rat liver lipids were studied. The different fatty acids incorporations follow analogous patterns in every hormonal state in vitro. Incorporation rate is faster in normal animals, but adrenalectomy or the administration of cortisol produces a marded delay. Cortisol does not modify the anomalism observed in the adrenoprival state. In vivo, the incorporation of palmitic acid into the different liver lipids--for the same hormonal state--does not follow the same pattern.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 136","pages":"357-70"},"PeriodicalIF":0.0,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12155876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Etiopathogenesis of true male homosexuality (androgenic insufficiency?)]. [真男同性恋的发病机制(雄激素功能不全?)]。
Revista iberica de endocrinologia Pub Date : 1976-05-01
F A de la Balze
{"title":"[Etiopathogenesis of true male homosexuality (androgenic insufficiency?)].","authors":"F A de la Balze","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Clinical and experimental studies have suggested the author the possibility that an androgenic insufficiency, during embryogenesis or the perinatal period, may be a determinant factor in the pathogenesis of the anomalies of homosexual behavior. In the author's opinion, the androgenic anomalies seen in the genuine male homosexual have no pathogenic significance, but are a repetition of what occured during embryogenesis of the perinatal period, at the time when these anomalies had a pathogenic role.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 135","pages":"225-43"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11974908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dynamics of growth hormone secretion in patients with primary hypothyroidism, before and after treatment with thyroideal hormones]. [原发性甲状腺功能减退患者甲状腺激素治疗前后生长激素分泌的动态变化]。
Revista iberica de endocrinologia Pub Date : 1976-05-01
F Hervás, G Morreale de Escobar, F Escobar del Rey y, V Pozuelo Escudero
{"title":"[Dynamics of growth hormone secretion in patients with primary hypothyroidism, before and after treatment with thyroideal hormones].","authors":"F Hervás,&nbsp;G Morreale de Escobar,&nbsp;F Escobar del Rey y,&nbsp;V Pozuelo Escudero","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Growth hormone (GH) secretion was studied in a group of alut controls and a series of patients with primary hypothyroidism before and after treatment with thyroid hormones. Intravenous insulin-induced hypoglycemia was the stimulus used (0,1 UI/kg body weight). It is concluded that in primary hypothyroidism, GH secretion is almost absent due to relative inactivity of the somatotropic cells and/or lack of GH-RH. This decreased secretory response becomes rapidly normal after treatment with physiological doses of thyroid hormones.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 135","pages":"263-73"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12133816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of the thyroid in the development of intestinal hydroxylases]. [甲状腺在肠道羟化酶发育中的作用]。
Revista iberica de endocrinologia Pub Date : 1976-05-01
J M Castellanos Llorens
{"title":"[Effect of the thyroid in the development of intestinal hydroxylases].","authors":"J M Castellanos Llorens","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors studied the saccharidase levels in the intestines of rats during the perinatal period. Sucrase and maltase values increase with advancing time, while lactase values decrease also age-dependently. The thyroid gland has a decisive role in the intestinal maturation of fats. In an assessment of circulating blood thyroxin levels, the authors found that the amount of thyroxin at birth is practically undetectable (less than 0,05 mug/100 ml expressed in iodine), rapidly increasing up to adult levels (3,8 mug/100 ml) 22 days after birth.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 135","pages":"275-87"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12133817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Differences found in serum serotonin between a group of normal and subjects of obese patients following intravenous tolbutamide administration]. [静脉注射托布丁胺后正常和肥胖患者血清血清素的差异]。
Revista iberica de endocrinologia Pub Date : 1976-05-01
C Castel Aznar, J Tamarit Torres, F Hervás Olivares, V Pozuelo Escudero
{"title":"[Differences found in serum serotonin between a group of normal and subjects of obese patients following intravenous tolbutamide administration].","authors":"C Castel Aznar,&nbsp;J Tamarit Torres,&nbsp;F Hervás Olivares,&nbsp;V Pozuelo Escudero","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have studied the effect of the i.v. administration of 1 g tolbutamide upon glycemia, insulinemia and serotoninemia in normal subjects and obese patients. We have seen an elevation of the last two variables in direct relationship with the previous blood sugar levels. The baseline serotonin level in obese people is higher than in normals, but the tolbutamide induced elevation is of a lesser magnitude. We believe this fact is due to the competitive action of insulin, as our obese patients have shown to have a \"hyperinsulinism\" with \"disinsulinism\".</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 135","pages":"239-61"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12133815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of a new hypoglycemic drug on the blood sugar in rats]. [一种新型降糖药对大鼠血糖的影响]。
Revista iberica de endocrinologia Pub Date : 1976-03-01
S Perán, A M De Diego, F Arcas, A Maté, M Morell
{"title":"[Effect of a new hypoglycemic drug on the blood sugar in rats].","authors":"S Perán,&nbsp;A M De Diego,&nbsp;F Arcas,&nbsp;A Maté,&nbsp;M Morell","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A sesquiterpenic lactone has been isolated from an extract of Artemisia cannariensis Lee by Clark's method and column chromatography. The hypoglycemic effects of the drug have been assayed in rats, as compared to different doses of insulin and a known sulphonylures drug. The subatance, which has been identified as vulgarine by professor Gonzalez, has highly significant hypoglycemic effects when administered orally or intravenously in relation to glycemia curves of rats previously injected with saline.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 134","pages":"171-8"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12118276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Secretion of growth hormone in hyperthyroidism]. [甲状腺机能亢进中生长激素的分泌]。
Revista iberica de endocrinologia Pub Date : 1976-03-01
F Hervás, G Morreale de Escobar, F Escobar Del Rey, V Pozuelo
{"title":"[Secretion of growth hormone in hyperthyroidism].","authors":"F Hervás,&nbsp;G Morreale de Escobar,&nbsp;F Escobar Del Rey,&nbsp;V Pozuelo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors studied growth hormone (GH) secretion in a group of adult controls and another group of hyperthyroid patients after stimulation with intravenous insulin-induced (0,1 IU/kg) hypoglycemia, aiming to clear out the problem of discrepancies in literature concerning GH secretion in hyperthyroidism. They concluded that in this syndrome, GH levels are significantly higher than those of controls. The GH releasing response is normal, though it could be expected to be decreased due to decreased pituitary GH contents as a result of permanent somatotrophic cell stimulation.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 134","pages":"147-55"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12118273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical trial with glypentide. Comparison with the hypoglycemic activity of other sulfonylurea compounds]. 格列肽的临床试验。与其他磺脲类化合物的降糖活性比较[j]。
Revista iberica de endocrinologia Pub Date : 1976-03-01
J M López, G Khoury, R C Fernández, J M COBOS, J L Huelva
{"title":"[Clinical trial with glypentide. Comparison with the hypoglycemic activity of other sulfonylurea compounds].","authors":"J M López,&nbsp;G Khoury,&nbsp;R C Fernández,&nbsp;J M COBOS,&nbsp;J L Huelva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 53 sulphonylurea-treated diabetic patients, the activity of glypentide and the patients' general tolerance of the drug were studied. The results show that the new oral hypoglycemic drug has a similar, and superior in many instances, activity to other similar drugs such as glybenclamide and glypizide, and to the activity of the classical sulphonylureas (chlorpropamide and carbutamide). The patients' tolerance of the drug was excellent. No digestive disorders, undesirable side effects or hypoglycemias were seen in the patients. Analysis of lipid levels showed that glypentide induces a significant decrease in total lipid and cholesterol values, being this action more marked in patients with normal body weight non-treated with a hypocaloric diet.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"23 134","pages":"181-96"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11973220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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