[Incorporation of 1-C14 palmitic acid into liver lipids of rats in different hormanal states].

Revista iberica de endocrinologia Pub Date : 1976-07-01
J M De Gandarias, M Lacort, B Fernández, F Ainz, J J Goiriena De Gandarias, S Rabanal, J M Pamo
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Abstract

Adrenalectomy and/or cortisol-induced variations in the in vivo and in vitro incorporation of 14C-palmitic acid 1 into the different fractions of rat liver lipids were studied. The different fatty acids incorporations follow analogous patterns in every hormonal state in vitro. Incorporation rate is faster in normal animals, but adrenalectomy or the administration of cortisol produces a marded delay. Cortisol does not modify the anomalism observed in the adrenoprival state. In vivo, the incorporation of palmitic acid into the different liver lipids--for the same hormonal state--does not follow the same pattern.

[1-C14棕榈酸在不同激素状态大鼠肝脂中的掺入]。
研究了肾上腺切除术和/或皮质醇诱导的大鼠肝脂不同部位14c -棕榈酸1在体内和体外的掺入变化。在体外实验中,不同的脂肪酸结合在每种激素状态下都遵循类似的模式。正常动物的掺入率更快,但肾上腺切除术或使用皮质醇会产生明显的延迟。皮质醇不能改变在肾上腺素状态下观察到的异常。在体内,棕榈酸与不同肝脏脂质的结合——在相同的激素状态下——并不遵循相同的模式。
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