{"title":"The Relationship between Food Security and Gestational Diabetes among Pregnant Women.","authors":"Shontreal Cooper, Maura Graham, Chia-Ling Kuo, Raminder Khangura, Adrienne Schmidt, Stephanie Bakaysa","doi":"10.1055/s-0042-1751082","DOIUrl":"https://doi.org/10.1055/s-0042-1751082","url":null,"abstract":"<p><p>The objective were to: (1) evaluate associations between food security and women diagnosed with gestational diabetes mellitus (GDM) and (2) evaluate if women in food insecure (FI) households had adverse maternal and neonatal outcomes. This was an observational study from October 2018 until September 2019. Postpartum resident clinic patients who delivered term, singleton infant at 37 weeks' or longer gestation were screened. Participants completed a survey using the U.S. Household Food Security Survey Module (US HFSSM). Survey responses were classified as: food secure (FS) and FI (marginal, low, very low FS). The primary outcome was GDM. Our secondary outcome was neonatal intensive care unit (NICU) admissions for hypoglycemia. We evaluated the rate of GDM in FS and FI groups. Demographic data included: prepregnancy body mass index, total weight gain during pregnancy, birth weight, and mode of delivery. A logistic regression model was used to analyze the association between food insecurity and GDM. A <i>p</i> -value of less than 0.05 was considered statistically significant. There were 150 patients screened to participate; of these, 70 patients were enrolled (36 GDM and 34 without GDM [NGDM]). More patients in FI households, 71% ( <i>n</i> = 17), were diagnosed with GDM, compared with 33% ( <i>n</i> = 15) in the FS (FS) households (adjusted odds ratio 7.05; <i>p</i> < 0.01). Of patients who reported FI, 50% ( <i>n</i> = 12) were black, 46% ( <i>n</i> = 11) Hispanic, and 4% ( <i>n</i> = 1) Caucasian, compared with 13% ( <i>n</i> = 6) black, 30% ( <i>n</i> = 14) Hispanic, and 57% ( <i>n</i> = 26) Caucasian in patients who reported FS ( <i>p</i> < 0.001). Although not significant, 25% ( <i>n</i> = 6) of neonates from an FI household had an NICU admission for hypoglycemia compared with 7% ( <i>n</i> = 3) from an FS household ( <i>p</i> = 0.054). Pregnant women with GDM are more likely to experience FI than those with NGDM. Infants of mothers in FI households also had increased rates of NICU admission for hypoglycemia.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 3","pages":"e131-e138"},"PeriodicalIF":0.9,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/dc/10-1055-s-0042-1751082.PMC9410985.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33444399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-08-06eCollection Date: 2022-04-01DOI: 10.1055/a-1830-2903
Johannah M Scheurer, Meghan L Fanta, Gretchen A Colbenson, Sophie Arbefeville, Patricia Ferrieri
{"title":"Early-Onset Neonatal Sepsis Caused by Vertical Transmission of <i>Pasteurella multocida</i>.","authors":"Johannah M Scheurer, Meghan L Fanta, Gretchen A Colbenson, Sophie Arbefeville, Patricia Ferrieri","doi":"10.1055/a-1830-2903","DOIUrl":"https://doi.org/10.1055/a-1830-2903","url":null,"abstract":"<p><p>Early-onset neonatal sepsis contributes substantially to neonatal morbidity and mortality. Presenting signs and symptoms vary, and most causes are due to a limited number of common microbes. However, providers must be cognizant of unusual pathogens when treating early-onset sepsis (EOS). We report a case of a term neonate who presented with respiratory distress, lethargy, and hypoglycemia 5 hours after birth. He was treated for presumed EOS with blood culture, revealing an unusual pathogen, <i>Pasteurella multocida</i> . Sepsis from this pathogen is a rarely reported cause of early onset neonatal sepsis. Our report is one of few that implicate vertical transmission with molecular diagnostic confirmation of <i>P</i> . <i>multocida</i> , subspecies septica. The neonate was treated with antibiotics and supportive care and recovered without ongoing complications. Providers should maintain an index of suspicion for rare causes of neonatal EOS. For these unusual cases, precise microbial identification enables understanding to provide best clinical care and anticipation of complications.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 2","pages":"e123-e126"},"PeriodicalIF":0.9,"publicationDate":"2022-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/d6/10-1055-a-1830-2903.PMC9356768.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40612232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-08-06eCollection Date: 2022-04-01DOI: 10.1055/s-0042-1748521
Gregory E Zemtsov, Anthony E Swartz, Jeffrey A Kuller
{"title":"Prenatal Diagnosis of Arhinia.","authors":"Gregory E Zemtsov, Anthony E Swartz, Jeffrey A Kuller","doi":"10.1055/s-0042-1748521","DOIUrl":"https://doi.org/10.1055/s-0042-1748521","url":null,"abstract":"<p><p>Arhinia is a rare congenital anomaly that is not typically associated with known genetic mutations and is usually discovered after an affected infant is born. Prenatal diagnosis is important because neonates with arhinia often require specialized respiratory support with creation of an artificial airway. We present a case of isolated arhinia diagnosed on second-trimester ultrasound. A patient presented for routine ultrasound at 18 weeks gestation, and nasal tissues were absent in an otherwise morphologically normal appearing fetus. Cell free fetal DNA was unremarkable. The patient elected to undergo termination of pregnancy by dilation and evacuation. Subsequent genetic analysis confirmed a normal fetal karyotype and microarray, and no examination of fetal structural anatomy was possible. Antenatal diagnosis of arhinia is important to guide maternal-fetal care decisions and requires methodical sonographic evaluation to identify this malformation prior to delivery.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 2","pages":"e127-e130"},"PeriodicalIF":0.9,"publicationDate":"2022-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/5b/10-1055-s-0042-1748521.PMC9356769.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40612233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-02-04eCollection Date: 2022-01-01DOI: 10.1055/s-0041-1742235
Robert E Murphy, Jane C Ibekwe, Stella I Ibekwe, Jerrie S Refuerzo
{"title":"A Structural, Cognitive, and Behavioral Model for Error Analysis of Group B Streptococcus Prophylaxis in Pregnancy.","authors":"Robert E Murphy, Jane C Ibekwe, Stella I Ibekwe, Jerrie S Refuerzo","doi":"10.1055/s-0041-1742235","DOIUrl":"https://doi.org/10.1055/s-0041-1742235","url":null,"abstract":"<p><p>The objective of this study was to develop a structural-cognitive-behavioral model for error analysis of group B streptococcus (GBS) prophylaxis failure, classify delivery cases into this model, and examine compliance with treatment guidelines. A retrospective, cohort study was conducted of women with liveborn pregnancies greater than 24 weeks in April 2018 at a single hospital. We created a structural-cognitive-behavioral model of five assessments for adherence to GBS prophylaxis guidelines and then classified these into four distinct error stages. A descriptive analysis was performed to determine if the pregnancy had a perfect process, a GBS prophylaxis failure, or a fortuitous outcome. There were 313 women who met the study criteria. The rate of GBS positive was 12.8%, negative 37.4%, and unknown 49.8%. The most common errors were cognitive perception errors related to incorrectly documenting GBS status, 57.7% ( <i>N</i> = 79). Of these errors, 15.2% ( <i>N</i> = 12) led to GBS prophylaxis failure. Perfect outcomes occurred in 62.7% ( <i>N</i> = 196) women, GBS prophylaxis failure occurred in 13.7% ( <i>N</i> = 43), and fortuitous outcomes occurred in 23.6% ( <i>N</i> = 74). In our study, we were able to identify structural, cognitive, and behavioral errors that contribute to GBS prophylaxis failures. In other cases, these errors may contribute to fortuitous outcomes.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 1","pages":"e17-e26"},"PeriodicalIF":0.9,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/14/10-1055-s-0041-1742235.PMC8816629.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39905079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-02-04eCollection Date: 2022-01-01DOI: 10.1055/s-0041-1742236
Arlin Delgado, Jay Schulkin, Charles J Macri
{"title":"Prenatal Genetic Screening and Diagnostic Testing: Assessing Patients' Knowledge, Clinical Experiences, and Utilized Resources in Comparison to Provider's Perceptions.","authors":"Arlin Delgado, Jay Schulkin, Charles J Macri","doi":"10.1055/s-0041-1742236","DOIUrl":"https://doi.org/10.1055/s-0041-1742236","url":null,"abstract":"<p><p><b>Objective</b> This survey study aimed to assess patient knowledge, clinical resources, and utilized resources about genetic screening and diagnostic testing. <b>Study Design</b> A one-time anonymous paper survey was distributed to 500 patients at a major urban obstetrics and gynecology department, and an online survey was sent to 229 providers. Descriptive statistics and chi-squared analyses were performed. <b>Results</b> In all, 466 of 500 patient surveys were completed, and 441 analyzed (88.2% response rate). Among providers, 66 of 229 (29.0% response rate) responded. Patients were on average 32 years old, 27 weeks pregnant, and most often reported a graduate degree level of education (47.4%). Over 75% of patients reported accurate knowledge of basic genetic statements. Patients reported that discussing screening and diagnostic testing with their provider was significantly associated with properly defining screening and diagnostic testing ( <i>p</i> < 0.001). Less than 10% of patients reported providers distributing web/video links, books, or any other resource; however, patients most often independently accessed web links (40.1%). <b>Conclusion</b> Our findings suggest a positive impact from patient and provider discussions in office on patient knowledge and understanding. Discrepancies between educational resources distributed in the clinic and individually accessed resources highlight possible areas of change. Future work should evaluate and implement differing resources to increase patient knowledge.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 1","pages":"e27-e32"},"PeriodicalIF":0.9,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/61/10-1055-s-0041-1742236.PMC8816620.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39905080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-02-04eCollection Date: 2022-01-01DOI: 10.1055/s-0041-1742268
Chase R Cawyer, Christina Blanchard, Kenneth H Kim
{"title":"Financial Literacy and Physician Wellness: Can a Financial Curriculum Improve an Obstetrician/Gynecologist Resident and Fellow's Well-Being?","authors":"Chase R Cawyer, Christina Blanchard, Kenneth H Kim","doi":"10.1055/s-0041-1742268","DOIUrl":"https://doi.org/10.1055/s-0041-1742268","url":null,"abstract":"<p><p><b>Objective</b> This study aimed to evaluate the effects of a financial literacy curriculum on resident and fellow's sense of well-being and financial stress. <b>Study Design</b> This single institution pilot study prospectively enrolled obstetrician/gynecologist (OB/GYN) medical trainees (residents and fellows) to take part in a five-part personal financial literacy curriculum during the 2019 to 2020 academic year. Topics covered included the following: financial education and its relationship to personal well-being, overview of financial terms and principles, budgeting, debt planning, and investing and giving. Primary outcomes were the improvement in well-being as measured by the Expanded Well-Being Index (E-WBI) and financial stress as measured by the Financial Stress Scale-College Version (FSS-CV) survey. <b>Results</b> Of the 35 residents and fellows who participated in the study, 21 (60%) completed the postintervention survey. After course completion, there was significant improvement in the individual's E-WBI ( <i>p</i> < 0.05) and no significant improvement in their FSS-CV ( <i>p</i> = 0.06). After completing the course, trainees agreed that financial literacy improved their sense of well-being ( <i>p</i> = 0.018). <b>Conclusion</b> Cultivating financial literacy is associated with an improvement in the sense of well-being in residents and fellows and should be considered for inclusion in other graduate medical education (GME) programs.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 1","pages":"e64-e68"},"PeriodicalIF":0.9,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/93/dc/10-1055-s-0041-1742268.PMC8816634.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39766916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-02-04eCollection Date: 2022-01-01DOI: 10.1055/s-0041-1741540
Catherine M Caponero, Dani G Zoorob, Victor Heh, Hind N Moussa
{"title":"The Effect of Video Education on Skin-to-Skin Contact at the Time of Delivery: A Randomized Controlled Trial.","authors":"Catherine M Caponero, Dani G Zoorob, Victor Heh, Hind N Moussa","doi":"10.1055/s-0041-1741540","DOIUrl":"https://doi.org/10.1055/s-0041-1741540","url":null,"abstract":"<p><p><b>Objective</b> The objective of this study was to measure the impact of video education at the time of admission for delivery on intent and participation in skin-to-skin contact (SSC) immediately after birth. <b>Methods</b> This study was a randomized controlled trial of educational intervention in women ( <i>N</i> = 240) of 18 years or older admitted in anticipation of normal spontaneous term delivery. Alternate patients were randomized into video ( <i>N</i> = 120) and no video ( <i>N</i> = 120) groups. Both groups received a survey about SSC. The video group watched an educational DVD and completed a postsurvey about SSC. <b>Results</b> During the preintervention survey, 89.2% of those in the video group compared with 83.3% of those in the no video group indicated that they planned to use SSC ( <i>p</i> = 0.396). After the video, 98.3% planned to do SSC after delivery ( <i>p</i> < 0.001). However, only 59.8% started SSC within 5 minutes of delivery in the video group and only 49.4% started SSC within 5 minutes of delivery in the no video group ( <i>p</i> = 0.17). <b>Conclusion</b> Video education alters the intention and trends toward participation in SSC within 5 minutes of delivery. Despite the plans for SSC, however, there was no significant difference in rates between the two groups. These findings support that obstacles, other than prenatal education, may affect early SSC. <b>Key Points</b> Significant obstacles impact skin-to-skin rate.Video education alters skin-to-skin intent.Video education can improve skin-to-skin rate.Education can happen at the time of delivery.Video education can impact mothers and infants.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 1","pages":"e10-e16"},"PeriodicalIF":0.9,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9c/1b/10-1055-s-0041-1741540.PMC8816630.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39905078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-02-04eCollection Date: 2022-01-01DOI: 10.1055/s-0041-1742270
Ernesto A Figueiro-Filho, Na T S Robinson, Jose Carvalho, Johannes Keunen, Monique Robinson, Cynthia Maxwell
{"title":"Hemodynamic Assessment of Pregnant People with and without Obesity by Noninvasive Bioreactance: A Pilot Study.","authors":"Ernesto A Figueiro-Filho, Na T S Robinson, Jose Carvalho, Johannes Keunen, Monique Robinson, Cynthia Maxwell","doi":"10.1055/s-0041-1742270","DOIUrl":"https://doi.org/10.1055/s-0041-1742270","url":null,"abstract":"<p><p><b>Objective</b> This study aimed to identify cardiovascular differences between pregnant people with and without obesity for trimester-specific changes in hemodynamic parameters using noninvasive cardiac output monitoring (NICOM). <b>Study Design</b> This study is a pilot prospective comparative cohort between pregnant people with and without obesity. Hemodynamic assessment was performed with NICOM (12-14, 21-23, and 34-36 weeks) during pregnancy. <b>Results</b> In first trimester, pregnant people with obesity had higher blood pressure, stroke volume (SV), total peripheral resistance index (TPRI), and cardiac output (CO). Pregnant people with obesity continued to have higher SV and cardiac index (second and third trimesters). During the first trimester, body mass index (BMI) positively correlated with SV, TPRI, and CO. Fat mass showed a strong correlation with TPRI. BMI positively correlated with CO during the second trimester and fat mass was positively associated with CO. During the third trimester, TPR negatively correlated with BMI and fat mass. <b>Conclusion</b> Fat mass gain in the period between the first and second trimesters in addition to the hemodynamic changes due to obesity and pregnancy contribute to some degree of left ventricular diastolic dysfunction which was manifested by lower SVs. Future work should investigate the possible causative role of obesity in the cardiovascular changes identified in people with obesity.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 1","pages":"e69-e75"},"PeriodicalIF":0.9,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/c5/10-1055-s-0041-1742270.PMC8816622.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39766917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-02-04eCollection Date: 2022-01-01DOI: 10.1055/s-0041-1742267
Robert L Thurer, Sahar Doctorvaladan, Brendan Carvalho, Andrea T Jelks
{"title":"Limitations of Gravimetric Quantitative Blood Loss during Cesarean Delivery.","authors":"Robert L Thurer, Sahar Doctorvaladan, Brendan Carvalho, Andrea T Jelks","doi":"10.1055/s-0041-1742267","DOIUrl":"https://doi.org/10.1055/s-0041-1742267","url":null,"abstract":"<p><p><b>Objective</b> This study examined the accuracy, sources of error, and limitations of gravimetric quantification of blood loss (QBL) during cesarean delivery. <b>Study Design</b> Blood loss determined by assays of the hemoglobin content on surgical sponges and in suction canisters was compared with QBL in 50 parturients. <b>Results</b> QBL was moderately correlated to the actual blood loss ( <i>r</i> = 0.564; <i>p</i> < 0.001). Compared with the reference assay, QBL overestimated blood loss for 44 patients (88%). QBL deviated from the assayed blood loss by more than 250 mL in 34 patients (68%) and by more than 500 mL in 16 cases (32%). Assayed blood loss was more than 1,000 mL in four patients. For three of these patients, QBL was more than 1,000 mL (sensitivity = 75%). QBL was more than 1,000 mL in 12 patients. While three of these had an assayed blood loss of more than 1,000 mL, 9 of the 46 patients with blood losses of less than 1,000 mL by the assay (20%) were incorrectly identified as having postpartum hemorrhage by QBL (false positives). The specificity of quantitative QBL for detection of blood loss more than or equal to 1,000 mL was 80.4%. <b>Conclusion</b> QBL was only moderately correlated with the reference assay. While overestimation was more common than underestimation, both occurred. Moreover, QBL was particularly inaccurate when substantial bleeding occurred. <b>Key Points</b> QBL is inaccurate in cesarean delivery.QBL deviated from the assay result by more than 500 mL in 32% of cases.QBL sensitivity and specificity for hemorrhage is 75.0% (95% confidence interval [CI]: 0.19-0.93) and 80.4% (95% CI: 0.69-0.92), respectively.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 1","pages":"e36-e40"},"PeriodicalIF":0.9,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/83/10-1055-s-0041-1742267.PMC8816625.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39905082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AJP ReportsPub Date : 2022-02-04eCollection Date: 2022-01-01DOI: 10.1055/s-0041-1742269
Megan S Varvoutis, Azza E Abdalla, Sarah K Dotters-Katz
{"title":"Does the Degree of Maternal Fever in the Setting of Chorioamnionitis Lead to Adverse Neonatal Outcomes?","authors":"Megan S Varvoutis, Azza E Abdalla, Sarah K Dotters-Katz","doi":"10.1055/s-0041-1742269","DOIUrl":"https://doi.org/10.1055/s-0041-1742269","url":null,"abstract":"<p><p><b>Objective</b> The effect of the degree of maternal fever in the setting of chorioamnionitis on neonatal morbidity is unclear. The objective of this study is to assess the association between high maternal fevers (≥ 39°C) on neonatal morbidity. <b>Study Design</b> Secondary analysis of Maternal-Fetal Medicine Units (MFMU) Cesarean Registry data obtained from 1999 to 2002 among singleton gestations with chorioamnionitis. Women with a temperature less than 39°C (low fever) compared with those with greater than or equal to 39°C (high fever). Primary outcome was a composite of adverse neonatal outcomes such as death, sepsis, necrotizing enterocolitis, grade-3 or -4 intraventricular hemorrhage, seizure within 24 hours of delivery, intubation within 24 hours of delivery, and requiring cardiopulmonary resuscitation. Demographic characteristics compared using Fisher's exact and Wilcoxon's rank-sum test as appropriate. Multivariate logistic regression analysis with performed to control for cofounders. Stratified analysis also performed to assess outcomes in term infants. <b>Results</b> Of 1,313 included women, 1,200 (91.3%) were in the low fever group and 113 (8.7%) were in the high fever group. Women in the high fever group were more likely to be African American and group B <i>Streptococcus</i> positive. No difference in primary outcome was noted between the groups (38.9% high fever vs. 35.8% low fever, <i>p</i> = 0.54). High maternal fever was associated with increased risk of NICU admission (48.1 vs. 50.4%, <i>p</i> = 0.02). When controlling for African American race, preterm birth, and delivery route, patients with high fever were not more likely to have adverse neonatal outcomes (adjusted odds ratio [aOR] = 1.28, 95% confidence interval [CI]: 0.84, 1.98). In the analysis limited to term infants, when controlling for confounders, high fever, similarly, was not associated with increased odds of adverse neonatal outcomes (aOR = 1.59, 95% CI: 0.96, 2.65). <b>Conclusion</b> The degree of maternal fever does not appear to be associated with an increased likelihood of adverse neonatal outcomes. Better understanding maternal factors that affect neonatal morbidity in the setting of chorioamnionitis is critical. <b>Key Points</b> High maternal fever in the setting of chorioamnionitis does not appear to have an increased likelihood of adverse neonatal outcomes.It is important to identify factors that may increase the risk of adverse outcomes such as early onset sepsis.Maternal fever may not be a strong indicator for neonatal outcomes and antibiotic protocols.</p>","PeriodicalId":7645,"journal":{"name":"AJP Reports","volume":"12 1","pages":"e58-e63"},"PeriodicalIF":0.9,"publicationDate":"2022-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/4e/10-1055-s-0041-1742269.PMC8816624.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39905085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}