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Revista de farmacia e bioquimica da Universidade de Sao Paulo最新文献

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[Evolution of the total volatile basis and trimethylamine in fish and their use as an indicator of its quality]. [鱼中总挥发性碱和三甲胺的演变及其作为质量指标的用途]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
M H Mendes, F M Lajolo
{"title":"[Evolution of the total volatile basis and trimethylamine in fish and their use as an indicator of its quality].","authors":"M H Mendes,&nbsp;F M Lajolo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors followed trimetylamine (TMA) and Total Volatile Basis (TVB) evolution in some Brazilian fishes during ice storage at 4 degrees C for 15 days. The fishes studied were: Micropogon furniere, Umbrina canosai, Centropomus undecimalis, Cysnoscion acoupa; samples were taken and analyzed each 48 h. Each species was stored eviscerated (E) or not-eviscerated (NE) in order to estabilish a possible advantage of on board evisceration. The results showed a log. relation between TVB or TMA percentage in the fish tissues and the days of storage; Mathematical models were established for predicting \"storage life\" for each fish out the basis of its amine content. Evisceration, immediatly after capture retarded deterioration and seem to be a useful practice.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"303-22"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12408042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pharmacokinetics of benziodarone labelled with I-131]. [I-131标记苯并碘酮的药代动力学]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
S Shimizu, J C Barberio
{"title":"[Pharmacokinetics of benziodarone labelled with I-131].","authors":"S Shimizu,&nbsp;J C Barberio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Regarding the importance of benziodarone (Retrangor) -- 2-ethyl-3-(3',5'-diiodo-4'-hidrovibenzoyl)benzofuran -- in medical practic, in respect of its vasodilator and uricosuric action, a working plan was developed intending to study the biological distribution of the drug in rats Wistar and, using the plasmatic curve, to find out the existence of other compartements besides the intravascular one. With these data, the rhytms of benziodarone exchange were established, simulating its distribution in the organism. It was possible to develop this working project because the benziodarone structure could be labelled with iodine-131, using an isotopic exchange reaction, having chloramine T as an oxidant agent. The labelled compound was employed as radioactive tracer, and its specific activities varied from 18 uCi/mg to 20 uCi/mg.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"267-92"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12265586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Latentiation of therapeutic drugs. VI. Preparation of l-amino-4-naphtylazoic ambonates of schistosomicides]. 治疗药物的潜伏期。六、杀血吸虫剂l-氨基-4-萘甲酸酯的制备[j]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
A Korolkovas, G N Yang, T Haraguchi, M Itaya
{"title":"[Latentiation of therapeutic drugs. VI. Preparation of l-amino-4-naphtylazoic ambonates of schistosomicides].","authors":"A Korolkovas,&nbsp;G N Yang,&nbsp;T Haraguchi,&nbsp;M Itaya","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the purpose of obtaining latent forms, with prolonged action and less toxic, of four schistosomicidal 1-amino-4-naphthylazoderivatives synthesized early, embonates of these compounds were prepared by reacting disodium and tetrasodium embonates with hydrochlorides of the four naphthylazoderivatives. The eight embonates thus obtained were sent for biological assays.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"185-91"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12408037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Parasitological survey, with special reference to schistosomiasis mansoni, conducted in the region of Jacupiranga (Ribeira valley, State of São Paulo). Survey of the location and distribution of planorbidian snails in the State of São Paulo. VII]. [在Jacupiranga地区(<s:1>圣保罗州Ribeira山谷)进行了寄生虫学调查，特别涉及曼氏血吸虫病。<s:1>圣保罗州planorbiddian钉螺的分布和分布调查。七)。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
M D Perez, S Hyakutake, J A Areas, F F Filho
{"title":"[Parasitological survey, with special reference to schistosomiasis mansoni, conducted in the region of Jacupiranga (Ribeira valley, State of São Paulo). Survey of the location and distribution of planorbidian snails in the State of São Paulo. VII].","authors":"M D Perez,&nbsp;S Hyakutake,&nbsp;J A Areas,&nbsp;F F Filho","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of a parasitological survey, emphasizing particularly schistosomiasis mansoni, are presented. The area under study was the district of Cajati, situated in the \"município\" of Jacupiranga (State of São Paulo, Brazil) near schistosomiasis-endemic areas in Vale do Ribeira. Though the presence of parasitized people by Schistosoma mansoni has been reported and focuses of Biomphalaria tenagophila, the species responsible for the spreading of the parasites through great areas of the state, has been localized, it has not been reported any autochthonous case nor the presence of schistosoma-infected planorbidian snails. As a contribution to the planorbidical chart of the State, it is reported as original the discovery of the species Drepanotrema cimex and D. depressissimum in that area. The detection of antitoxoplasmic antibodies in a sample of the studied population showed a significant prevalence rate corresponding to 76,4%.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"401-15"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12417745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Preliminary bromatologic study of sorghum grains cultivated in Brazil]. [巴西栽培高粱籽粒的初步色谱学研究]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
H F Oria, M M de Lima
{"title":"[Preliminary bromatologic study of sorghum grains cultivated in Brazil].","authors":"H F Oria,&nbsp;M M de Lima","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"323-36"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12408043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Synthesis and biological trial of 1-methylene-4-naphthylazo polymer derivates]. [1-亚甲基-4-萘偶氮聚合物衍生物的合成及生物学试验]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
A Korolkovas, J Pellegrino, G N Yang
{"title":"[Synthesis and biological trial of 1-methylene-4-naphthylazo polymer derivates].","authors":"A Korolkovas,&nbsp;J Pellegrino,&nbsp;G N Yang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the purpose of preparing latent forms of six naphthylazoderivatives (five of them are schistosomicidal agents), polymers of these chemotherapeutic agents were synthesized in a two-step reaction. First, polymeric 1-methyleneaminonaphthalene (II) was synthesized by condensing 1-naphthylamine with formaldehyde. Subsequently, coupling of II with five sulfonamides (of which four are moieties of schistosomicidal agents) and 5-aminouracil (which is a part of another schistosomidical agent) yielded polymeric 1-methyleneamino-4-naphthylazoderivaties (IIIa-f). In bioligical tests in mice experimentally infected by Schistosoma mansoni, the six new polymers were found inactive.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"227-36"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12408039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Preliminary study of 3 algae of the Ulvaceae family from the Mãe Luisa beach (RN)]. [来自m<e:1> e Luisa海滩(RN)的3种Ulvaceae科藻类的初步研究]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
M de Jesus Torres Caldas, M A Campos
{"title":"[Preliminary study of 3 algae of the Ulvaceae family from the Mãe Luisa beach (RN)].","authors":"M de Jesus Torres Caldas,&nbsp;M A Campos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Samples of marine algae from Brazilian coast were analysed for the proximate composition, calcium, phosphorus, iron and aminoacids. Ulva fasciata, Enteromorpha intestinalis and Enteromorpha flexuosa have been studied, specimens being collected at \"Mãe Luisa\" beach in the State of Rio Grande do Norte, between the months of September and November 1973. Quantitative determinations of the aminoacid composition of each were made and a comparison of the results pointed to the similarity of composition of all species examined. Limiting aminoacids were methionine, lysine, isoleucine, tryptophan and cystine, except for Enteromorpha intestinalis and Enteromorpha flexuosa, in which triptophan and cystine, respectively, were not limiting.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"337-50"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12408046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Methods of studing intestinal absorption in vivo and in vitro]. [体内和体外肠道吸收的研究方法]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
T L de Medina, N L Rodrigues, D M Nogueira, H S Medina
{"title":"[Methods of studing intestinal absorption in vivo and in vitro].","authors":"T L de Medina,&nbsp;N L Rodrigues,&nbsp;D M Nogueira,&nbsp;H S Medina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors describe a simple method for the perfusion of everted and in situ intestine. The technique offers the same advantages of other methods and allows the measurement of the uptake of substances from the intestinal lumen and estimates the absorption by the intestinal wall. The technique affords the biochemical studies of the action and effects of drugs on the mechanism of the intestinal absorption.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"381-9"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12410383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prevalence of anti-Toxoplasma gondii antibodies in blood donors of Natal (RN)]. [新生儿献血者抗刚地弓形虫抗体的流行情况]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
I F de Araujo, B S Anna, S Hyakutake
{"title":"[Prevalence of anti-Toxoplasma gondii antibodies in blood donors of Natal (RN)].","authors":"I F de Araujo,&nbsp;B S Anna,&nbsp;S Hyakutake","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors present the results of survey to detect anti-Toxoplasma gondii antibodies in 183 sera samples from donors in five blood banks in Natal -- Rio Grande do Norte, Brazil, through indirect immunofluorescence test. In this survey 151 reactive cases were found, starting with the titer of 1:16, in a rate of 82,5%. Considering as valid dilutions only titers equal or superior to 1:256, the rate found is of 43.7%. The higher titer found was 1:16.000 (1.3%). In the examined cases, the minimal age was 17 and maximal, 58. The age of most donors (91 cases) ranged from 21 to 30 years. Comparative studies were carried out with similar inquiries performed in other regions.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"417-25"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12410388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Coconut (Cocos nucifera L.) and the preparation of a milk substitute]. [椰子(Cocos nucifera L.)和牛奶替代品的制备]。
Revista de farmacia e bioquimica da Universidade de Sao Paulo Pub Date : 1975-07-01
M I Chitarra, M A Campos
{"title":"[Coconut (Cocos nucifera L.) and the preparation of a milk substitute].","authors":"M I Chitarra,&nbsp;M A Campos","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coconut (Cocos nucifera, L.) is an abundant product in Brazil. The authors studied the use of the protein fraction to prepare \"milk-substitute\" beverages. The analyses were made on albumen, copra and cake. Protein coconut extraction was tried with water; NaCl solutions in different concentrations; HCl and NaOH solutions in different concentrations; HCl and NaOH solutions at different pH values. The extracted proteins were analysed for aminoacid composition and chemical score. The best results of protein extraction were obtained with NaCl 1 M solution using the ratio 100:75 (coconut:solution). The extracted proteins were coagulated with trichloroacetic acid and separated with water and analysed for aminoacid composition and solubility.</p>","PeriodicalId":76437,"journal":{"name":"Revista de farmacia e bioquimica da Universidade de Sao Paulo","volume":"13 2","pages":"351-74"},"PeriodicalIF":0.0,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12420962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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