Prostaglandins and medicine最新文献

Platelet aggregation induced by arachidonic acid and thromboxane generation in patients with hypertension or cerebrovascular disease 花生四烯酸和血栓素在高血压或脑血管病患者中诱导血小板聚集

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90045-8

Masayasu Matsumoto, Masahito Kusunoki, Osamu Uyama, Atsushi Fujisawa, Tomohiro Matsuyama, Shotaro Yoneda, Kazufumi Kimura, Hiroshi Abe

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引用次数: 16

Inhibition of vasoconstrictor and vasodilator responses by PGE1 in the intestinal vascular bed of the cat PGE1对猫肠血管床血管收缩和血管扩张反应的抑制作用

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90044-6

H.L. Lippton, P.J. Kadowitz

{"title":"Inhibition of vasoconstrictor and vasodilator responses by PGE1 in the intestinal vascular bed of the cat","authors":"H.L. Lippton, P.J. Kadowitz","doi":"10.1016/0161-4630(81)90044-6","DOIUrl":"10.1016/0161-4630(81)90044-6","url":null,"abstract":"<div>The effects of PGE1 on vascular resistance, vasoconstrictor responses to sympathetic nerve stimulation and pressor hormones and vasodilator responses to bradykinin and nitroglycerin were investigated in the feline mesenteric vascular bed. Infusions of PGE1, 1.0 and 0.1 μg/min, into the superior mesenteric artery dilated the mesenteric vascular bed and markedly inhibited vasoconstrictor responses to sympathetic nerve stimulation, norepinephrine and angiotensin and to vasodilator responses to bradykinin and nitroglycerin. The response to the highest dose of bradykinin was reversed to a pressor response during infusion of PGE1. In contrast, mesenteric perfusion pressure and vasoconstrictor responses to nerve stimulation and pressor hormones and vasodilator responses to bradykinin and nitroglycerin were unchanged during the lowest rate of infusion of PGE1, 0.01 μg/min. When the decrease in (initial value) vascular resistance was taken into account by expressing vasodilator responses on a percent decrease basis, infusion of PGE1 reduced or reversed the vasodilator responses to bradykinin whereas the vasodilator responses to nitroglycerin were not altered. Results of these studies suggest that PGE1 may influence vasomotor tone and responses to pressor hormones and bradykinin in the mesenteric vascular bed of the cat.</div>","PeriodicalId":76381,"journal":{"name":"Prostaglandins and medicine","volume":"7 6","pages":"Pages 537-552"},"PeriodicalIF":0.0,"publicationDate":"1981-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0161-4630(81)90044-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17850697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Bioconversion of arachidonic acid to prostaglandins by graafian follicles and stroma from the human ovary 花生四烯酸在人卵巢毛囊和基质中向前列腺素的生物转化

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90042-2

Kazuo Satoh, Naoki Mitsuhashi, Yasuo Kawai, Katsuyuki Kinoshita, Shoichi Sakamoto

引用次数: 5

Indomethacin inhibits arachidonic acid metabolism via lipoxygenase and cyclo-oxygenase in hamster isolated lungs 吲哚美辛通过脂加氧酶和环加氧酶抑制仓鼠离体肺花生四烯酸代谢

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90049-5

Pekka Uotila, Jussi Männistö, Niklas Simberg, Kaarlo Hartiala

引用次数: 34

Effect of protein aggregation on murine splenic prostaglandin F2α levels 蛋白聚集对小鼠脾前列腺素F2α水平的影响

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90037-9

Kenneth J. Wieder, David R. Webb

引用次数: 1

An intrauterine silastic system for the sustained release of indomethacin 一种用于吲哚美辛缓释的宫内弹性系统

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90046-X

P.V. Peplow, P.R. Hurst

引用次数: 10

Effects of arachidonic acid hydroperoxides on vascular and non-vascular smooth muscle 花生四烯酸氢过氧化物对血管和非血管平滑肌的影响

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90043-4

David Aharony, J.Bryan Smith, Edward F. Smith III, Allan M. Lefer

引用次数: 20

Ethanol inhibits the formation of endoperoxide metabolites in human platelets 乙醇抑制人血小板内过氧化物代谢物的形成

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90041-0

Daniel H. Hwang

引用次数: 32

Monthly bibliography on prostaglandins prepared by the University of Sheffield Biomedical Information Service Sheffield S10 2TN, England November 1981 由英国谢菲尔德大学生物医学信息服务中心谢菲尔德s102tn于1981年11月编写的前列腺素月度参考书目

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90050-1

引用次数: 0

Feedback moduiaticn of gilcose-induced insulin secretion by arachidonic acid meiabol: Possible molecular mechanisms and relevance to diabetes mellitus 花生四烯酸代谢对葡萄糖诱导的胰岛素分泌的反馈调节:可能的分子机制及其与糖尿病的关系

Prostaglandins and medicine Pub Date : 1981-12-01 DOI: 10.1016/0161-4630(81)90048-3

Stewart A. Metz

引用次数: 17